Search  for anything...

Seresto Large Dog Vet-Recommended Flea & Tick Treatment & Prevention Collar for Dogs Over 18 lbs. | 2-Pack

  • Based on 109,552 reviews
Condition: New
Checking for the best price...
$107.98 Why this price?

Buy Now, Pay Later


As low as $18.00 / mo
  • – 6-month term
  • – No impact on credit
  • – Instant approval decision
  • – Secure and straightforward checkout

Ready to go? Add this product to your cart and select a plan during checkout.

Payment plans are offered through our trusted finance partners Klarna, PayTomorrow, Affirm, Afterpay, Apple Pay, and PayPal. No-credit-needed leasing options through Acima may also be available at checkout.

Learn more about financing & leasing here.

Selected Option

Free shipping on this product

FREE 30-day refund/replacement

To qualify for a full refund, items must be returned in their original, unused condition. If an item is returned in a used, damaged, or materially different state, you may be granted a partial refund.

To initiate a return, please visit our Returns Center.

View our full returns policy here.


Availability: In Stock.
Fulfilled by Amazon

Arrives Friday, Sep 26
Order within 16 hours and 31 minutes
Available payment plans shown during checkout

Size: 2 Pack


Features

  • Vet-recommended, premium flea and tick protection for dogs and puppies without the price tag
  • Long-lasting flea and tick collar kills and repels fleas for 8 continuous months
  • Seresto is veterinarian recommended flea and tick collar
  • Starts working within 24 hours to kill and repel fleas by contact so pests dont have to bite your dog to die
  • Hassle-free, non-greasy, easy-to-use flea and tick protection

Description

Give your dog long-lasting protection against fleas and ticks with a Seresto Large Dog flea and tick collar. Unlike other flea and tick protection, Seresto Large Dog flea and tick collars kill and repel fleas and ticks for eight continuous months. Seresto Large Dog flea and tick collars are recommended by veterinarians, stocked by 8,000 vet clinics and have been trusted by pet owners for nearly a decade.Seresto Large Dog collars make your dog’s comfort a priority by killing fleas and ticks on contact, so pests don’t have to bite your dog to die. Existing fleas die within 24 hours after initial application of the collar. After 24 hours, any new fleas on the dog are killed within 2 hours with protection against further flea infestation lasting 8 months. The prevention of infestations with new ticks starts at 48 hours after application of the collar. 48 hours after application, any new ticks are repelled and/or killed in as quickly as 6 hours. Seresto Large Dog collars protect against common pests like deer ticks, American dog ticks, brown dog ticks, and Lone Star ticks; they’re also effective against chewing lice. Fleas and ticks not only cause discomfort; fleas can transmit bartonellosis or tapeworm. Ticks can transmit Borrelia burgdorferi which causes Lyme Disease. Check the product label for information on potential side effects.Seresto Large Dog flea and tick collars are for dogs at least 7 weeks old, and there’s no prescription needed. They’re odorless, non-greasy and water resistant to swimming, exposure to rain or sunlight, bathing, and shampoo treatment.Seresto is a trademark of Elanco or its affiliates.Elanco Animal Health, data on file Seresto Large Dog is water resistant and remains effective following a shampoo treatment, swimming or after exposure to rain or sunlight. Under normal conditions, effectiveness lasts for 8 months. In order to maintain an eight- month duration, dogs must not be bathed more than once per month. For dogs that swim once a month or more, the control duration is reduced to 5 months for flea control and reduced to 7 months for tick control.Seresto is rigorously regulated worldwide with your pet in mind. Fake Seresto collars are ineffective and can put your furry friend at risk for expensive flea and tick infestations and painful flea and tick bites which can result in transmission of certain diseases. One of the best ways to make sure your Seresto collar is authentic is by making sure it’s “Sold By” one of our authorized sellers. Check out the trusted list before shopping: , Petco, Entirelypets, Petstoreusa, Pets Go Here - Pet Store, Heartland Veterinary Supply.

Brand: Seresto


Item Form: Collar


Scent: Unscented


Item Weight: 0.55 Pounds


Active Ingredients: Imidacloprid, Flumethrin


Item Volume: 27 Cubic Inches


Allergen Information: Allergen-Free


Dog Breed Size: Large


Age Range (Description): 7 weeks and older


UPC:


Is Discontinued By Manufacturer ‏ : ‎ No


Product Dimensions ‏ : ‎ 3 x 5 x 5 inches; 8.8 ounces


Manufacturer recommended age ‏ : ‎ 1 month and up


Item model number ‏ : ‎ 86904616


Department ‏ : ‎ Unisex-Adult


Date First Available ‏ : ‎ April 3, 2015


Manufacturer ‏ : ‎ Elanco US Inc


Best Sellers Rank: #95 in Pet Supplies (See Top 100 in Pet Supplies) #1 in Dog Flea Collars


#1 in Dog Flea Collars:


Item Weight: 8.8 ounces


Department: Unisex-Adult


Manufacturer: Elanco US Inc


Item model number: 86904616


Date First Available: April 3, 2015


Item Package Dimensions L x W x H: 5.28 x 5.08 x 3.19 inches


Item Dimensions LxWxH: 3 x 5 x 5 inches


Item Weight: 0.55 Pounds


Brand Name: Seresto


Target Audience Keyword: dogs


Directions: How to apply the Seresto collar on your dog 1. Remove the collar from its packaging. 2. Unroll the collar and remove the small plastic connectors from inside the collar, ensuring that no remnants remain. 3. Insert the end of the collar through the buckle and loops. 4. Adjust the collar around your dog's neck until it fits comfortably on them. 5. Two fingers should fit beneath the collar and neck to ensure it's not too tight. Any excess length of the collar beyond an inch past the loops should be cut off, unless it is on a growing puppy, where some additional length may be needed for adjustment as the puppy grows. 6. Check periodically and adjust fit if necessary, especially on growing puppies.


Model Name: Seresto


Color: Grey


Size: 2 Pack


Material: Plastic


Age Range Description: 7 weeks and older


Number of Items: 2


Style: Large Dog Only


Breed Recommendation: Large


Specific Uses for Product: Parasites


Frequently asked questions

If you place your order now, the estimated arrival date for this product is: Friday, Sep 26

Yes, absolutely! You may return this product for a full refund within 30 days of receiving it.

To initiate a return, please visit our Returns Center.

View our full returns policy here.

  • Klarna Financing
  • Affirm Pay in 4
  • Affirm Financing
  • Afterpay Financing
  • PayTomorrow Financing
  • Financing through Apple Pay
Leasing options through Acima may also be available during checkout.

Learn more about financing & leasing here.

Top Amazon Reviews


  • Perfect and worth the money
Size: 1 Pack
I highly recommend this collar. Well worth the money! It is durable and it works great. Have been using this for two years and it protects my adorable fur baby from fleas and ticks. He is picky and won't do chews or pills, so this is perfect! I don't have to put monthly treatments on him and when my eight months is near I just put another collar on him. I did the math and this is well worth it and cheaper than the chews! ... show more
Reviewed in the United States on August 26, 2025 by Selena

  • LONG THOROUGH REVIEW from a skeptical pessimist
Size: 1 Pack
This collar is PERFECT. Okay so I was really really super skeptical about buying this for several reasons: - I hate the thought of my two pups having to constantly wear an extra collar - I've tried the flea/tick collars from Walmart and they were greasy and had a weird smell but even worse, they did NOT work. - I've read some of the horrifying reviews - I'm just a skeptical person and simply didn't think this would work. BUT IM A BELIEVER NOW. For context, I have a 3yr old short haired ~45lbs pup (pitbull, lab, corgi mix) and and a 7yr old long haired ~30-35lbs pup (Lhasa Apso terrier mix). I live in Maryland where the weather is just always unpredictable. I feel like we have like 6 seasons instead of 4. We have woods in the back of our house which deer always like to frequent, along with a swamp/pond across the street. This spring and the start of this summer we had a monsoon season where afterwards, there was an annoying infestation of ticks (mostly Lone Star and Deer ticks). It was disgusting. I legitimately could not take my dogs out for a walk without finding at least 4 ticks on them afterwards and on me!!! And this is on top of treating my dogs with the monthly tick/flea topical oil treatment. That's how bad it was, which is what prompted me to buy the Seresto collars. (I bought Large for both of them) Once I did and placed them on my dogs, after maybe like 1-2 days, I have not found a single tick on them. I know that sounds so far fetched but I don't know what else to say because it's absolutely true. It does take about 1-2 days for the medication to get into the system (from experience and from *I think* what the package said) because I still did find a few ticks on them the next day. But after that, not a single tick! They've been wearing the collars for about 1.5 months now so I'm still keeping an eye on them (I plan on updating this review after 7-8 months to see if the claim of lasting 8 months is legitimate). Right now though, I am sooo happy. Now I want to address some of the other reviews I saw. After I saw some of the pictures of rashes this collar left on some dogs, I was worried, especially cause my smaller one already has exist in skin issues. But both are doing perfectly well with no skin issues from the collar. I don't want to be presumptuous and I may be totally wrong, but I'm thinking maybe the rashes the other dogs had were because they're not used to wearing collars? So they just kept itching at it? Maybe? I say that because for me at least, my dogs are used to wearing their regular collars nearly 24/7 since they were babies. So when I added the Seresto collars, they were unphased. But then again I'm also aware that just like humans, each dog reacts differently. Luckily, My dogs have no rash problems from the collars. As for some claiming that the collar doesn't work.. I'm not sure what to say other than that they really truly work for my dogs, and I live in a heavily tick infested area. It really is like night and day in terms of how well this collar works at preventing tick bites. Especially with my long haired dog since ticks would easily hide in her fur. The collar isn't greasy nor does it have a strong emanating odor. BUT it's still medicated so it still has a very slight residue to it but nothing that interferes with everyday life. I'm sold and plan on continuing with this product from here on out. NO MORE GREASY NASTY SMELLY TOPICAL MONTHLY TICK GREASE! **Side note** Make sure you read the packaging instructions carefully!! They mention a few things like about how the efficacy is shortened to something like 5 months for dogs who swim a lot, or how the collar is designed to unlatch if the dog pulls incase it gets stuck on something (which I thoroughly appreciate) so you CANNOT substitute this as a walking collar! The collar DOES unlatch if you hold onto it and your dog pulls (personal experience: guests came over, one jumps and I accidentally grabbed the Seresto collar and it unlatched). But you CAN reattach it!! So definitely take the time to read the package instructions. Hope this helps! I really loveeeee this collar. THANK YOU SERESTO!!! ... show more
Reviewed in the United States on July 16, 2016 by Amazon Customer

  • Great purchase!
Size: 1 Pack
Great purchase. It has worked to keep my 80lb pit-mix rescue dog free of fleas and ticks all spring and summer, on one collar. When compared to the monthly topical treatments, the price is great. It stays in place really well and there’s no residue coming from it. My dog tolerates it well, with no skin irritation or scratching. It’s durable and flexible. It was super easy to put on him and I plan on sticking with this collar in the future. It ... show more
Reviewed in the United States on September 13, 2025 by Dacy

  • My honest thoughts, great purchase
Size: 1 Pack
f you’re tired of remembering monthly flea treatments or dealing with messy spot-ons, the Seresto flea collar might be your new best friend (besides your actual pet, of course). I!ve used them for my dogs (30lb, 50lb, & 160 lb) and here’s the deal: it actually works. It claims to protect against fleas and ticks for up to 8 months, and surprisingly, it kind of delivers. Within a couple days, I noticed way fewer fleas, and ticks? Haven’t seen one since. What I like: • Super low-maintenance – You put it on and forget about it (well, mostly). • No gross smell or sticky stuff – It’s not greasy, and you won’t smell chemicals every time your pet walks by. • Water-resistant – Bath time or a quick swim doesn’t kill the magic (though too many baths might shorten its life a bit). • Long-term win – It’s a bit pricey upfront, but if you break it down over 8 months, it’s cheaper than monthly treatments. A few things to watch out for: • Skin sensitivity – Some pets might react to it. Mine have been completely fine. • Not a bug shield – It doesn’t repel fleas and ticks, it just kills them once they make contact. • Fake products online – Definitely buy from a trusted store or your vet. There are some sketchy knockoffs floating around that don’t work (or worse). Bottom line: If your pet tolerates wearing it, the Seresto collar is a total game-changer. It saves you time, mess, and gives your pet long-lasting protection. Just keep an eye on them for the first couple days after putting it on, and you’re good to go. ... show more
Reviewed in the United States on June 5, 2025 by Karen & Shane

  • Does the job and lasts long time!!
Size: 1 Pack
I love using this collar on my dog! I e used it for over 5 years and she’s never had any fleas or ticks! I’ve even seen a mosquito lite on her and die. I also like that it lasts for 8 months! She seems to have no side effects from it at all! Great product!!
Reviewed in the United States on July 3, 2025 by T. Scales

  • Peace of Mind for You and Your Dog — Works as Promised
Size: 1 Pack
I’ve tried multiple flea and tick treatments over the years, but the Seresto Large Dog Collar stands out in ways that typical reviews often overlook. This isn’t just a “long-lasting flea and tick collar”. Instead, it’s a genuinely stress-free solution that actually works. My dog wears it comfortably all day, and I haven’t had to worry about monthly spot-on treatments or messy applications. What really differentiates this collar is the consistent protection it provides. Fleas and ticks simply don’t stick around, and I’ve noticed a real improvement in my dog’s comfort and coat condition. The collar is adjustable and secure, so it fits well without restricting movement, and it’s vet-recommended, which gives me extra confidence in its safety and efficacy. If you’re looking for a reliable, low-maintenance way to keep your dog protected from pests year-round, this is one of the few products that actually delivers on its promises. Ordering from Amazon is easy, and it arrives ready to use, making it incredibly convenient for busy pet owners. No bad smell, leakage and seems to work immediately, speed is not a concern. ... show more
Reviewed in the United States on September 21, 2025 by Michelle Kim

Can't find a product?

Find it on Amazon first, then paste the link below.
Checking for best price...