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Capstar for Dogs (nitenpyram), Fast-Acting Oral Flea Treatment for Dogs Over 25+ lbs, Vet-Recommended Flea Medication Tablets Start Killing in 30 Minutes, 6 Doses

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Availability: In Stock.
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Arrives Friday, Mar 20
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Size: 6 Count


Style: Large Dog 25+ lbs


Features

  • Fast-Acting Flea Treatment: CAPSTAR (nitenpyram) oral flea medicine for dogs starts killing adult fleas in just 30 minutes
  • Tackle Flea Infestations Fast: With one dose of CAPSTAR flea treatment, you can watch the dead fleas fall off your pet
  • Treat Reinfestations Fast: If your pet gets reinfested with fleas, simply give another dose of this dog flea treatment as often as once a day
  • No Prescription Needed: Fast, effective flea treatment at home with nitenpyram for dogs that's available over the counter
  • Intended Use: CAPSTAR Oral flea tablets for dogs (57 mg) is safe for puppies 4 weeks and older that weigh 25.1-125 pounds

Description

CAPSTAR flea tablets for dogs (nitenpyram) is a fast-acting flea treatment tablet that starts killing fleas in only 30 minutes. A single dose of CAPSTAR dog flea medicine kills 90% of adult fleas within 4 hours for dogs. Pet parents can give this oral flea treatment and watch the dead fleas fall off your pet. CAPSTAR flea tablets are available for dogs and puppies 25.1-125 pounds, and 4 weeks of age or older.

Brand: Capstar


Item Form: Tablets


Scent: Unscented


Item Weight: 0.01 Pounds


Active Ingredients: Nitenpyram


Item Volume: 0.01 Fluid Ounces


Allergen Information: Dairy Free


Dog Breed Size: Large


Age Range (Description): All Life Stages


UPC:


Is Discontinued By Manufacturer ‏ : ‎ No


Product Dimensions ‏ : ‎ 0.63 x 5.75 x 4.5 inches; 0.1 ounces


Item model number ‏ : ‎ CA4925Y07AMZ1


Date First Available ‏ : ‎ July 25, 2014


Manufacturer ‏ : ‎ Vetio Animal Health


Best Sellers Rank: #540 in Pet Supplies (See Top 100 in Pet Supplies) #1 in Dog Flea Pills


#1 in Dog Flea Pills:


Customer Reviews: 4.1 4.1 out of 5 stars (55,221)


Item Weight: 0.096 ounces


Manufacturer: Vetio Animal Health


Item model number: CA4925Y07AMZ1


Date First Available: July 25, 2014


Item Package Dimensions L x W x H: 4.96 x 3 x 0.87 inches


Item Dimensions LxWxH: 0.63 x 5.75 x 4.5 inches


Item Weight: 0.01 Pounds


Brand Name: Capstar


Target Audience Keyword: dogs


Directions: CAPSTAR Tablets should be administered orally, at a minimum dosage rate of 1.0 mg/kg (0.45 mg/lb) body weight, according to the Recommended Dosage Schedule below. Weigh your pet prior to administration to ensure proper dosage. Do not administer to pets under 2 pounds. CAPSTAR may be used as needed, as often as once per day, whenever you see fleas on your pet.


Model Name: Capstar Flea Treatment for Dogs


Color: Green


Size: 6 Count


Age Range Description: All Life Stages


Number of Items: 1


Style: Large Dog 25+ lbs


Breed Recommendation: Medium & Large Dogs


Included Components: Capstar Flea Tablet for Dogs 57 mg


Specific Uses for Product: Parasites


Frequently asked questions

If you place your order now, the estimated arrival date for this product is: Friday, Mar 20

Yes, absolutely! You may return this product for a full refund within 30 days of receiving it.

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View our full returns policy here.

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Top Amazon Reviews


  • **Effective and Easy Flea Control for My Dog**
Size: 6 Count Style: Large Dog 25+ lbs
**Effective and Easy Flea Control for My Dog** I’ve been using CAPSTAR flea medicine for my dog, and I’m really happy with the results. The pill is easy to give—no mess, no topical residue, and no fighting with my dog to apply it. Within a short time, I noticed a big reduction in scratching and flea activity, which was such a relief. What I like most is the convenience of a monthly pill. It fits easily into our routine and gives me peace of mind knowing my dog is protected. My dog didn’t have any noticeable side effects and took the pill without any issues. Overall, CAPSTAR has been a reliable and stress-free solution for keeping fleas under control. I’d definitely recommend it to dog owners looking for an effective oral flea treatment for anyone searching for a value on their dollar! ... show more
Reviewed in the United States on February 4, 2026 by Anna Watson

  • The best EVER for fleas
Size: 6 Count Style: Large Dog 25+ lbs
This is cheaper than what the vet offered Works BETTER than what he vet offered Kills fleas quicker than anything I have found Doesn't seem to bother the dogs when they take it Starts working within the first 30-45 minutes after they took it Couldn't be happier with this product EXCELLENT 👌👍
Reviewed in the United States on February 6, 2026 by Mae Bingman

  • Great flea medication works in 15 minutes
Size: 6 Count Style: Large Dog 25+ lbs
Was trying to find something that would not harm my pets and it would work very quick. Was recommended this. Let me tell you if you want to get rid of a flea infestation on an animal. These things are great. They work within 15 minutes within 24 hours all the fleas are gone your pet is happy and healthy fair warning some pets will get diarrhea from them not all but some I have 10 cats that I use these on two out of the 10 always get diarrhea when I get these pills to them like I said, they are great for getting rid of fleas fast and seem to be pretty harmless. Been using them for about eight months so far. ... show more
Reviewed in the United States on December 29, 2025 by Ric Copeland

  • Works as intended for new flea infestations. Not for ongoing ones.
Size: 6 Count Style: Large Dog 25+ lbs
This works best if you just discovered a new flea infestation on your pet. If you have an ongoing flea problem, I suggest getting one that targets all stages of the flea life cycle (your local veterinarian should help with suggesting the best products for your pet).
Reviewed in the United States on January 16, 2026 by W

  • Didn't work at all for Alaskan Malamutes
Size: 6 Count Style: Large Dog 25+ lbs
First, let me point out that CapStar is NOT a preventative! It is supposed to kill adult fleas on the dog but it doesn't prevent them from getting fleas again - not does it kill anything but adult fleas, which means you still need something (monthly topical or oral flea medicine) to kill the eggs and the larvae or those will obviously mature into adults and you and your pet are stuck in the vicious cycle. That being said, here is my first and only experience with CapStar. We have never had flea issues until this year. I have two Alaskan Malamutes - one 105 pound "short hair" and one 110 pound long hair. Clearly, they both have the Malamute thick double coat. We usually like K9 Advantix II for flea treatment/prevention. Early this summer, I bought the Amazon brand that has the same ingrediens as K9 Advantix II. It arrived with no expiration date and I'm not sure if that's the reason that it doesn't seem to work, that it's not the same formula or perhaps the fleas have become resistant... or it's just an especially overwhelming year for fleas. Either way, I thought by trying this first and THEN putting their prevention on within a day or two, it would work. I gave them each a CapStar pill, nervously watched for adverse reactions and thanked God they didn't seem to have any issues. It also didn't seem to help the flea situation - they continued scratching and biting as before. Because I didn't want to give them back to back, I waited for about 48 hours before giving another CapStar to each of them. Once again, no reaction but the scratching and chewing hasn't subsided at all nine hours later. In fact, I almost feel like both times, they were actually scratching more after the CapStar tablets?? It makes me wonder if it is actually not killing the fleas but just irritating them and making them more active and angry (or at least more hungry LOL). I really needed this to work and was hoping that in conjunction with a topical preventative, we would be able to both kill AND prevent reinfstation with a two prong attack. Sadly, we are just out more money, time and effort. I should mention that along side this effort, I treated the bedrooms that have carpet (the rest of the house has hard floors and we have a no-knap, outdoor rug in the living room because it can be power washed). Anyway, I sprayed the Vet's Best Flea & Tick Home Spray on the carpet, mattresses and washed bedding & blankets. It's difficult to get every possible location that a flea could be hiding but I was fortunate to be able to see a flea and spray Vet's Best directly on it. The Vet's Best spray killed it in less than 10 seconds. It does say that you can apply it to your dog's coat and rub it in down to their skin. That sounded too unrealistic with their thick coats but because it is natural, smells really nice IMO and obviously works, I think I will still attempt that on most of their coat/body, add Diatomaceous Earth to the floors, dog beds, rugs, etc and THEN try reapplying topical prevention. I just have to decide if I am going to use some of the 8 tubes I have left of the Amazon brand or try something else - I might pick up the Frontline Plus that's on sale at Costco tomorrow. *Edit* - I called my vet after posting this review to ask if Frontline Plus was working on fleas in our area (mid-Michgan in lower peninsula). I also spoke with the vet directly when taking this guy (in photo) in for his appointment that fall. The vet said that fleas had become more resistant to topicals and developed a thicker exoskeleton. In her opinion, she said the only thing that was working was oral prevention (like Nexgard). Ultimately, that's what we did - put them both on Nexgard until the cold Michigan winters helped kill the outdoor population and we could all breathe a sigh of relief. We never returned to topicals since this experience but have friends with multiple dogs (2 German Shepherds and a long hair Alaskan Malamute) who continued to use Advantix II (the name brand version) directly from their vet and said they haven't experienced issues. Hope my struggle and experience was helpful in some way but no matter which way you go, I think you can skip the unnecessary step of Capstar and not only save a bit of money but save your dog from extra chemicals that don't offer any real relief or added benefit. ... show more
Reviewed in the United States on September 22, 2023 by Kimberly W. Kimberly W.

  • It works wonders
Size: 6 Count Style: Large Dog 25+ lbs
Ok so I have 3 small dogs 25lb, 20lb and around 18lb I bought the big dog pack give and split one pill for my 2 smaller dogs, I just used it today and so far is good, now I want to add that it takes more than 30 to act also your dog will itch like crazy at around the 20min mark, this happened with all 3 dogs I got a little concerned for a minute because they were all scratching like crazy but I could see the fleas just running around so I guess I make sense unfortunately they were probably eating them up :( after like 20 more minutes I started seeing the fleas just walking slowly and defended but nothing crazy, also most of them didn’t just fall off they died there and I had to comb them out with a flea comb, I was locked on a small bathroom with all 3 of them and after like 45 minutes I gave them a bath with equal parts dish soap, apple c vinegar and like a spoon of baking soda let them marinate for a good 5-10 min and rinse after all that I saw a lot of them just washing out so make sure you bath them after treatment unless you want to find the nasty bugs around your home. I also bought fleas collar to help protect them and groomed them pretty short so I can keep an eye on them. ... show more
Reviewed in the United States on January 4, 2026 by Mother of 3 Mother of 3

  • Doesn't work as well as I had hoped, but it can kill some fleas
Size: 6 Count Style: Small Dog 2-25 lbs
Fleas on dog do not all die off after feeding to dog, but it does get rid of some. Had an easier time spraying dog with a safe to use flea spray bottle and getting more results. The price isn't worth the product either, should be cheaper.
Reviewed in the United States on January 4, 2026 by Chris Bartolo

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