Capstar for Dogs (nitenpyram), Fast-Acting Oral Flea Treatment for Dogs Over 25+ lbs, Vet-Recommended Flea Medication Tablets Start Killing in 30 Minutes, 6 Doses
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Availability:
In Stock.
Arrives
Sep 4 – Sep 5
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Size: 6 Count
Style: Over 25 lbs
Features
- Fast-Acting Flea Treatment: CAPSTAR (nitenpyram) oral flea medicine for dogs starts killing adult fleas in just 30 minutes
- Tackle Flea Infestations Fast: With one dose of CAPSTAR flea treatment, you can watch the dead fleas fall off your pet
- Treat Reinfestations Fast: If your pet gets reinfested with fleas, simply give another dose of this dog flea treatment as often as once a day
- No Prescription Needed: Fast, effective flea treatment at home with nitenpyram for dogs that's available over the counter
- Intended Use: CAPSTAR Oral flea tablets for dogs (57 mg) is safe for puppies 4 weeks and older that weigh 25.1-125 pounds
Description
CAPSTAR flea tablets for dogs (nitenpyram) is a fast-acting flea treatment tablet that starts killing fleas in only 30 minutes. A single dose of CAPSTAR dog flea medicine kills 90% of adult fleas within 4 hours for dogs. Pet parents can give this oral flea treatment and watch the dead fleas fall off your pet. CAPSTAR flea tablets are available for dogs and puppies 25.1-125 pounds, and 4 weeks of age or older.
Brand: Capstar
Item Form: Tablets
Scent: Unscented
Item Weight: 4.54 g
Active Ingredients: Nitenpyram
Item Volume: 0.01 fluid ounces
Allergen Information: Dairy Free
Dog Breed Size: Large
Unit Count: 6 Count
Color: Green
Product Dimensions : 0.63 x 5.75 x 4.5 inches; 0.1 ounces
Item model number : CA4925Y07AMZ1
Date First Available : July 25, 2014
Manufacturer : Vetio Animal Health
Best Sellers Rank: #131 in Pet Supplies (See Top 100 in Pet Supplies) #1 in Dog Flea Pills
#1 in Dog Flea Pills:
Customer Reviews: 4.2 4.2 out of 5 stars (32,792)
Brand Name: Capstar
Unit Count: 6 Count
Age Range Description: All Life Stages
UPC: 073091033387
Global Trade Identification Number: 87
Included Components: Capstar Flea Tablet for Dogs 57 mg
Item Type Name: Elanco Animal Health Capstar Flea Tablet for Dogs 57 mg (26-125 lbs)
Manufacturer: Vetio Animal Health
Model Number: CA4925Y07AMZ1
Manufacturer Part Number: CA4925Y07AMZ1
Warranty Description: Contact manufacturer for warranty information.
Item Form: Tablets
Scent Name: Unscented
Dog Breed Size: Large
Target Species: Dog
Item Weight: 4.54 g
Volume: 0.01 fluid ounces
Allergen Information: Dairy Free
Active Ingredients: Nitenpyram
Frequently asked questions
If you place your order now, the estimated arrival date for this product is:
Sep 4 – Sep 5
Yes, absolutely! You may return this product for a full refund within 30 days of receiving it.
To initiate a return, please visit our Returns Center.
View our full returns policy here.
To initiate a return, please visit our Returns Center.
View our full returns policy here.
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Top Amazon Reviews
Size: 6 Count
Style: Over 25 lbs
This works great! We started seeing dead fleas within an hour of taking these. My vet did warn me that these only last 24 hours so they are good for any fleas that are already on the dogs. They do not prevent future fleas so flea prevention is still needed. Will definitely be using again if I see active fleas on my dogs.
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Reviewed in the United States on July 31, 2026 by Serah Bechtel
Only stuff I've found so far this year that seems to be working -- sorry to say, both Advantage and Frontline seem to have lost their "oomph" against the current strains of fleas in my (Pacific Northwest) area. Wish this had residual effect, but then, it has never claimed to, so I certainly can't ding it for not doing what it very clearly states it can't do! Updated 11/7/2016: Still SO glad that at least this one product still works! With a house full of indoor-only cats, it seems pretty strange that fleas managed to get such a foothold, but somehow they had. Using Capstar every day for a couple of weeks, then every other day, was the ONLY thing that has finally gotten us flea-free. (Having read a technical article -- on the FDA web site -- years ago that showed nitenpyram is effective even at far, far, FAR lower doses than what is marketed -- and having read the package inserts and verified that ON THIS PRODUCT (please DON'T assume this applies to other products!!!) the only difference between the large dog and small dog/cat products is the dosage -- I buy the large dog doses and chop each tablet up into approximately 25-30 small pieces. Then for each cat I form a chicken flavor Whisker Lickin's soft treat around one of those tiny pieces, and most of the cats will happily eat the treat. (Some of them I have to give the tiny piece as a pill, but if they expect a Whisker Lickins or Friskies Party Mix treat right away afterward, almost all of them are cooperative.) Not only does chopping up each large dog tablet into about 25 cat-sized doses bring the cost down phenomenally, but it also makes me a LOT calmer about how much chemical I'm inflicting on the cats on a daily or every-other-day basis. (Although I'm now down to a "maintenance" program of only using it a couple of times a week, having gotten rid of the original infestation.)
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Reviewed in the United States on September 15, 2016 by Michelle A.
Size: 6 Count
Style: Over 25 lbs
Bought for my two dogs (husky and cane corso)..live in PNW- infestation is bad this year. I've tried almost everything. I called my vet and they recommended me this OTC oral med. Was a little hesitant but fleas was driving me nuts so I decided to purchase this oral med. This works but only kills fleas that is on your pet. This is not a preventative. Been on top of vacuuming, sprays, flea comb and laundry. Flea infestation is slowly going away inside my house. Will definitely purchase again and will recommend.
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Reviewed in the United States on December 4, 2025 by Gisel
Size: 6 Count
Style: Over 25 lbs
My labradoodle got fleas for the first time and it’s been 2 months fighting them on and off. To be honest, I’m not having a “massive” flea problem in the sense I’ve only caught a total of 5 fleas on her since it started, and I look for them with a flea comb daily. That being said, I know she has fleas because I keep finding flea dirt on her. It’s driving me mad. I have hardwood floors and have treated the house by vacuuming daily, washing all washable items in hot water, and spraying the “organic” pet-safe flea spray on rugs and furniture. My dog is also on monthly topical anti flea meds. But something’s clearly not working, so yesterday I sprayed all rugs and furniture with a black label raid flea killer. The smell is super strong and toxic for humans and animals, so you have to leave for a few hours. At night when I came back, I was sitting on my couch playing ball with my dog and I looked down and saw a giant flea on my arm. It bit me and I had to squish it a million times to die. I was bamboozled! I had NEVER seen a single flea NOT on my dog, and this one had jumped on me! I’d like to think the black label spray made it dizzy, and because my dog is covered in sprays, it jumped on me as a last resort. However, this was my last straw. I had not wanted to give her capstar because I’ve tried to stay away from oral preventatives and the possibility of neurological side effects terrifies me. But I had to do something. I got the capstar, fed it after breakfast, and anxiously watched her like a hawk for the following 6 hours to make sure she was okay. I was terrified and I’m so happy to report she had no side effects at all. Not even a sick stomach! Now, I gave her this pill thinking I would suddenly see a million fleas jump off my dog that had been previously hiding, but I did not see a single flea come off. I went in with a flea comb after as well, and did not find dead ones either. About 8h post pill, she’s still a little itchy, but I cannot find any fleas. I don’t know if this meant she had no fleas to begin with, or had very few ones that died and fell off without me noticing, but I was certainly expecting to see much more (or any at all??) coming off after reading other reviews. I’m hoping this means there are no more alive fleas on her, but I’m skeptical I didn’t see a SINGLE one besides the fat one on my arm last night. I am currently locked in my room with my dog as I re-sprayed the black label stuff everywhere else and will let it air overnight, and will give her a flea bath in the morning. So long story short, this might work better if you have a massive flea problem where you can easily find fleas on your dog. She’s only 45lb, so it’s not like she would’ve needed two pills. I will likely not use it again as I’m so confused, but at least happy we didn’t experience side effects.
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Reviewed in the United States on August 17, 2024 by Kathy
Size: 6 Count
Style: Over 25 lbs
Def seemed to work there were no more fleas on my dog for at almost 2 days…. I had also bought natural care home and tick room spray just in case. Hadn’t had an issue in the house yet at the time but you never know…. So Sprayed the whole house too. but then all of a sudden the 2nd day, in the room they decided to lay in for that night of the capstar treatment, I noticed suddenly had multitudes of fleas in it….like more fleas then I had def seen on the dogs or anywhere. Like I know larva falls off but I feel like the fleas were just temporarily knocked out onto the floor because we still had adults. & they actually don’t lay in this room often. Vacuumed cause I said maybe it was eggs larvae … And then ofc fleas were then obviously back on my dog because the pills are only for 24 hrs. used it again…just in case with the room spray again …& the same amount of fleas were present in the floor but not on the dogs. So I figured must be the natural care flea and tick spray. Maybe? So I Bought diamectrous earth bought another round of capstars & laid out DE. (And not just in cracks like everywhere all over the entire floor etc. The adults are gone now it seems (yay) but there’s still lil tiny ones jumping round like lunatics Apparrently it takes a while for DE to work on young fleas and doesn’t kill larvae. But kills adult fleas fast. So since the DE killed the adults and not capstar and since it’s only for a 24hr period that it at least gets them off the dogs I don’t feel like it was effective enough to be worth it so I bought nextstar instead this time. It apparrently lasts a whole month and hopefully that combination with them at least keeping the fleas off and the DE murdering them slowly, then this combo should hopefully be more effective. Def crossing my fingers. Cause my ankles werent bit up until after buying flea stuff. How ironic… & I just cannot take it anymore.
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Reviewed in the United States on August 5, 2023 by Jessica unlisted
Size: 6 Count
Style: Over 25 lbs
I didn’t believe some of the reviews when they were saying the fleas literally started jumping off and dying in 30 minutes. At about the 15-20 minute mark my dog started scratching a ton, roughly 20-25 minutes, literally had fleas falling off of him and coming to the surface of his coat and dying. I have a husky so it’s very hard to see any fleas on him, even during baths… I pulled off roughly 40ish dead fleas in the first hour of him taking it.. I feel terrible because I had no idea he had that many on him. Especially since I had put frontline on him 3-4 weeks prior. People are saying that it’s not a preventative, more of just to kill off what’s currently there. Most definitely killed a good chunk of them off. He’s still a little scratchy, but I would say majority of the fleas died.
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Reviewed in the United States on August 27, 2026 by Robert Carter
Size: 6 Count
Style: Over 25 lbs
First, let me point out that CapStar is NOT a preventative! It is supposed to kill adult fleas on the dog but it doesn't prevent them from getting fleas again - not does it kill anything but adult fleas, which means you still need something (monthly topical or oral flea medicine) to kill the eggs and the larvae or those will obviously mature into adults and you and your pet are stuck in the vicious cycle. That being said, here is my first and only experience with CapStar. We have never had flea issues until this year. I have two Alaskan Malamutes - one 105 pound "short hair" and one 110 pound long hair. Clearly, they both have the Malamute thick double coat. We usually like K9 Advantix II for flea treatment/prevention. Early this summer, I bought the Amazon brand that has the same ingrediens as K9 Advantix II. It arrived with no expiration date and I'm not sure if that's the reason that it doesn't seem to work, that it's not the same formula or perhaps the fleas have become resistant... or it's just an especially overwhelming year for fleas. Either way, I thought by trying this first and THEN putting their prevention on within a day or two, it would work. I gave them each a CapStar pill, nervously watched for adverse reactions and thanked God they didn't seem to have any issues. It also didn't seem to help the flea situation - they continued scratching and biting as before. Because I didn't want to give them back to back, I waited for about 48 hours before giving another CapStar to each of them. Once again, no reaction but the scratching and chewing hasn't subsided at all nine hours later. In fact, I almost feel like both times, they were actually scratching more after the CapStar tablets?? It makes me wonder if it is actually not killing the fleas but just irritating them and making them more active and angry (or at least more hungry LOL). I really needed this to work and was hoping that in conjunction with a topical preventative, we would be able to both kill AND prevent reinfstation with a two prong attack. Sadly, we are just out more money, time and effort. I should mention that along side this effort, I treated the bedrooms that have carpet (the rest of the house has hard floors and we have a no-knap, outdoor rug in the living room because it can be power washed). Anyway, I sprayed the Vet's Best Flea & Tick Home Spray on the carpet, mattresses and washed bedding & blankets. It's difficult to get every possible location that a flea could be hiding but I was fortunate to be able to see a flea and spray Vet's Best directly on it. The Vet's Best spray killed it in less than 10 seconds. It does say that you can apply it to your dog's coat and rub it in down to their skin. That sounded too unrealistic with their thick coats but because it is natural, smells really nice IMO and obviously works, I think I will still attempt that on most of their coat/body, add Diatomaceous Earth to the floors, dog beds, rugs, etc and THEN try reapplying topical prevention. I just have to decide if I am going to use some of the 8 tubes I have left of the Amazon brand or try something else - I might pick up the Frontline Plus that's on sale at Costco tomorrow. *Edit* - I called my vet after posting this review to ask if Frontline Plus was working on fleas in our area (mid-Michgan in lower peninsula). I also spoke with the vet directly when taking this guy (in photo) in for his appointment that fall. The vet said that fleas had become more resistant to topicals and developed a thicker exoskeleton. In her opinion, she said the only thing that was working was oral prevention (like Nexgard). Ultimately, that's what we did - put them both on Nexgard until the cold Michigan winters helped kill the outdoor population and we could all breathe a sigh of relief. We never returned to topicals since this experience but have friends with multiple dogs (2 German Shepherds and a long hair Alaskan Malamute) who continued to use Advantix II (the name brand version) directly from their vet and said they haven't experienced issues. Hope my struggle and experience was helpful in some way but no matter which way you go, I think you can skip the unnecessary step of Capstar and not only save a bit of money but save your dog from extra chemicals that don't offer any real relief or added benefit.
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Reviewed in the United States on September 22, 2023 by Kimberly W.
Size: 6 Count
Style: Over 25 lbs
My dogs, long hair chihuahua and Chinook, were infested with fleas! And we live in a house with 9 other dogs and 4 cats all infested with fleas. We got in on the 18th, gave it to them, and next day when we check the fleas we're all gone. The infestation was so bad when you picked up my chihuahua all you could see on his stomach were the fleas running all over the place, and I don't just mean a few here and there, it's a really bad infestation. But picked him up this morning and nothing. THIS IS A TEMPORARY FIX! The packaging even tells you this, it only kills adult fleas no the eggs. If you use this product I recommend treating your home immediately after. It does tell you you can use it daily, I haven't tried, but I'm going to wait a day or so for the eggs to hatch before reapplying. I'll try to remember to update the review to let you guys know how it goes. Both dogs are free of fleas even after interacting with the other dogs who still has fleas(they aren't my dogs, and these are really expensive to be buying for 11 dogs.) It's really nice to see my dog actually be able to sleep comfortably. These worked great and I will definitely be buying again. Gonna recommend this to everyone else in my house so they can give it to their pets as well and hopefully finally beat this infestation
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Reviewed in the United States on November 20, 2023 by Nikki