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Capstar for Dogs (nitenpyram), Fast-Acting Oral Flea Treatment for Dogs Over 25+ lbs, Vet-Recommended Flea Medication Tablets Start Killing in 30 Minutes, 6 Doses

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Availability: In Stock.
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Arrives Sunday, Jul 19
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Size: 6 Count


Style: Large Dog 25+ lbs


Features

  • Fast-Acting Flea Treatment: CAPSTAR (nitenpyram) oral flea medicine for dogs starts killing adult fleas in just 30 minutes
  • Tackle Flea Infestations Fast: With one dose of CAPSTAR flea treatment, you can watch the dead fleas fall off your pet
  • Treat Reinfestations Fast: If your pet gets reinfested with fleas, simply give another dose of this dog flea treatment as often as once a day
  • No Prescription Needed: Fast, effective flea treatment at home with nitenpyram for dogs that's available over the counter
  • Intended Use: CAPSTAR Oral flea tablets for dogs (57 mg) is safe for puppies 4 weeks and older that weigh 25.1-125 pounds

Description

CAPSTAR flea tablets for dogs (nitenpyram) is a fast-acting flea treatment tablet that starts killing fleas in only 30 minutes. A single dose of CAPSTAR dog flea medicine kills 90% of adult fleas within 4 hours for dogs. Pet parents can give this oral flea treatment and watch the dead fleas fall off your pet. CAPSTAR flea tablets are available for dogs and puppies 25.1-125 pounds, and 4 weeks of age or older.

Brand: Capstar


Item Form: Tablets


Scent: Unscented


Item Weight: 0.01 Pounds


Active Ingredients: Nitenpyram


Item Volume: 0.01 Fluid Ounces


Allergen Information: Dairy Free


Dog Breed Size: Large


Unit Count: 6 Count


Age Range (Description): All Life Stages


Is Discontinued By Manufacturer ‏ : ‎ No


Product Dimensions ‏ : ‎ 0.63 x 5.75 x 4.5 inches; 0.1 ounces


Item model number ‏ : ‎ CA4925Y07AMZ1


Date First Available ‏ : ‎ July 25, 2014


Manufacturer ‏ : ‎ Vetio Animal Health


Best Sellers Rank: #226 in Pet Supplies (See Top 100 in Pet Supplies) #1 in Dog Flea Pills


#1 in Dog Flea Pills:


Customer Reviews: 4.1 4.1 out of 5 stars (56,166)


Brand Name: Capstar


Age Range Description: All Life Stages


UPC: 073091033387


Global Trade Identification Number: 87


Manufacturer Part Number: CA4925Y07AMZ1


Model Number: CA4925Y07AMZ1


Unit Count: 6 Count


Included Components: Capstar Flea Tablet for Dogs 57 mg


Manufacturer: Vetio Animal Health


Item Type Name: Elanco Animal Health Capstar Flea Tablet for Dogs 57 mg (26-125 lbs)


Item Form: Tablets


Scent Name: Unscented


Dog Breed Size: Large


Target Species: Dog


Item Weight: 0.01 Pounds


Volume: 0.01 Fluid Ounces


Allergen Information: Dairy Free


Active Ingredients: Nitenpyram


Frequently asked questions

If you place your order now, the estimated arrival date for this product is: Sunday, Jul 19

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To initiate a return, please visit our Returns Center.

View our full returns policy here.

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Top Amazon Reviews


  • Temporary flea control
Size: 12 Count Style: Small Dog 2-25 lbs
Capstar works wonderfully on fleas. But it is only a temporary solution; about 24 hours. It can be given several consecutive days but it is quite expensive and is not a preventative. I still recommend it for fast, temporary flea control. But I wish I had bought a collar sooner.
Reviewed in the United States on May 24, 2026 by Leslie

  • Nuclear Option for a Flea Emergency
Size: 6 Count Style: Large Dog 25+ lbs
There's a specific panic that sets in when you see your dog scratching like they're auditioning for a cartoon and you realize the situation has escalated. That's exactly what Capstar is for. Pop one of these 57mg tablets and within 30 minutes you'll start seeing results. Within a few hours, the vast majority of adult fleas are gone. It's genuinely impressive to watch it work. The tablet is easy to give directly or hidden in a small amount of food, and in my experience larger dogs rarely put up a fight about it. The important thing to understand going in is what Capstar is and what it isn't. It's a one-day emergency treatment for adult fleas on the animal, not a preventative and not an egg-killer. Once the 24-hour window passes, fleas from the environment can re-infest your dog. That means Capstar works best as part of a broader strategy: treat the dog, treat the environment, then follow up with a longer-acting preventative. Used correctly, this is one of the most effective tools in the flea-fighting arsenal. The six-dose pack gives you flexibility for multiple dogs or repeat treatments if needed. Safe for dogs four weeks and older weighing over 25 pounds, and compatible with most other medications. A genuinely useful product when you need fast relief. ... show more
Reviewed in the United States on May 8, 2026 by John

  • Works quickly. My dog didn't turn her nose up at the pill. very easy.
Size: 6 Count Style: Large Dog 25+ lbs
I completely stand buy this product. It starts working in less than an hour. I don't like having my dog on meds all the time so I really appreciate being able to treat fleas when she gets them. It's a great product.
Reviewed in the United States on June 6, 2026 by ryan crawford

  • Effective.
Size: 6 Count Style: Small Dog 2-25 lbs
I think this Product would work good.
Reviewed in the United States on June 7, 2026 by Auristel M.

  • Didn't work at all for Alaskan Malamutes Didn't work at all for Alaskan Malamutes
Size: 6 Count Style: Large Dog 25+ lbs
First, let me point out that CapStar is NOT a preventative! It is supposed to kill adult fleas on the dog but it doesn't prevent them from getting fleas again - not does it kill anything but adult fleas, which means you still need something (monthly topical or oral flea medicine) to kill the eggs and the larvae or those will obviously mature into adults and you and your pet are stuck in the vicious cycle. That being said, here is my first and only experience with CapStar. We have never had flea issues until this year. I have two Alaskan Malamutes - one 105 pound "short hair" and one 110 pound long hair. Clearly, they both have the Malamute thick double coat. We usually like K9 Advantix II for flea treatment/prevention. Early this summer, I bought the Amazon brand that has the same ingrediens as K9 Advantix II. It arrived with no expiration date and I'm not sure if that's the reason that it doesn't seem to work, that it's not the same formula or perhaps the fleas have become resistant... or it's just an especially overwhelming year for fleas. Either way, I thought by trying this first and THEN putting their prevention on within a day or two, it would work. I gave them each a CapStar pill, nervously watched for adverse reactions and thanked God they didn't seem to have any issues. It also didn't seem to help the flea situation - they continued scratching and biting as before. Because I didn't want to give them back to back, I waited for about 48 hours before giving another CapStar to each of them. Once again, no reaction but the scratching and chewing hasn't subsided at all nine hours later. In fact, I almost feel like both times, they were actually scratching more after the CapStar tablets?? It makes me wonder if it is actually not killing the fleas but just irritating them and making them more active and angry (or at least more hungry LOL). I really needed this to work and was hoping that in conjunction with a topical preventative, we would be able to both kill AND prevent reinfstation with a two prong attack. Sadly, we are just out more money, time and effort. I should mention that along side this effort, I treated the bedrooms that have carpet (the rest of the house has hard floors and we have a no-knap, outdoor rug in the living room because it can be power washed). Anyway, I sprayed the Vet's Best Flea & Tick Home Spray on the carpet, mattresses and washed bedding & blankets. It's difficult to get every possible location that a flea could be hiding but I was fortunate to be able to see a flea and spray Vet's Best directly on it. The Vet's Best spray killed it in less than 10 seconds. It does say that you can apply it to your dog's coat and rub it in down to their skin. That sounded too unrealistic with their thick coats but because it is natural, smells really nice IMO and obviously works, I think I will still attempt that on most of their coat/body, add Diatomaceous Earth to the floors, dog beds, rugs, etc and THEN try reapplying topical prevention. I just have to decide if I am going to use some of the 8 tubes I have left of the Amazon brand or try something else - I might pick up the Frontline Plus that's on sale at Costco tomorrow. *Edit* - I called my vet after posting this review to ask if Frontline Plus was working on fleas in our area (mid-Michgan in lower peninsula). I also spoke with the vet directly when taking this guy (in photo) in for his appointment that fall. The vet said that fleas had become more resistant to topicals and developed a thicker exoskeleton. In her opinion, she said the only thing that was working was oral prevention (like Nexgard). Ultimately, that's what we did - put them both on Nexgard until the cold Michigan winters helped kill the outdoor population and we could all breathe a sigh of relief. We never returned to topicals since this experience but have friends with multiple dogs (2 German Shepherds and a long hair Alaskan Malamute) who continued to use Advantix II (the name brand version) directly from their vet and said they haven't experienced issues. Hope my struggle and experience was helpful in some way but no matter which way you go, I think you can skip the unnecessary step of Capstar and not only save a bit of money but save your dog from extra chemicals that don't offer any real relief or added benefit. ... show more
Reviewed in the United States on September 22, 2023 Reviewed in the United States on September 22, 2023 by Kimberly W.

  • Not Effective
Size: 6 Count Style: Small Dog 2-25 lbs
I didn’t find this to be effective within 30 minutes or after for our small dogs. Unfortunately this product did not work for us at all.
Reviewed in the United States on May 29, 2026 by Melynda Stanfield

  • Reliable Tick Protection for Rural Dogs 🐾
Size: 6 Count Style: Small Dog 2-25 lbs
Capstar works well for helping keep ticks under control. Ticks are very common in our rural area, and our dog spends time outdoors several times a day. We’ve been pleased with how effective it has been and appreciate the extra peace of mind when she’s outside playing. Easy to use and a helpful addition to her routine. ... show more
Reviewed in the United States on May 24, 2026 by Christie

  • Works well.
Size: 6 Count Style: Large Dog 25+ lbs
This is to kill adult fleas; not for eggs or baby fleas. Great to use to immediately kill fleas for infestation; then use a different application for longer term "killing" of fleas . I recommend.
Reviewed in the United States on May 31, 2026 by TC Ward

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