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Host Defense Mushrooms Lion's Mane - Supplement Capsules for Brain Health Support - Mushroom Support for Focus & Memory Function - Immune & Nervous System Supplement - 30 Capsules (15 Servings)*

  • Based on 14,463 reviews
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Arrives Sunday, Dec 7
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Size: 30 Count (Pack of 1)


Features

  • Lion's Mane for Brain Support: This mushroom supplement supports immune and nervous system health as well as brain health, making it an ideal dietary supplement for those wanting to aid their focus and memory*
  • Dietary Supplement with Mushroom Mycelium: Our brain and focus support supplement is formulated with Lion's Mane, "The Smart Mushroom," for daily brain support*
  • About Host Defense: Host Defense Mushrooms was founded by renowned mycologist Paul Stamets; our mushroom mycelium is certified organic, non-GMO, gluten-free, and grown in the USA*
  • Powered by Mushroom Mycelium: Our organic mushroom mycelium is grown on organic brown rice substrate; third-party studies show that mushroom mycelium and fermented rice substrate support your health*
  • Lion's Mane Dietary Supplement: As a dietary supplement, take 2 mushroom capsules once daily with food or on an empty stomach, or as recommended by your healthcare advisor

Brand: Host Defense


Item Form: Capsule


Manufacturer: Host Defense


Item Package Quantity: 1


Package Information: Bottle


Is Discontinued By Manufacturer ‏ : ‎ No


Product Dimensions ‏ : ‎ 1.88 x 1.88 x 3.5 inches; 1.76 ounces


Item model number ‏ :


Date First Available ‏ : ‎ June 17, 2013


Manufacturer ‏ : ‎ Host Defense


Best Sellers Rank: #2,465 in Health & Household (See Top 100 in Health & Household) #6 in Mushrooms Herbal Supplements


#6 in Mushrooms Herbal Supplements:


Customer Reviews: 4.6 4.6 out of 5 stars 14,463 ratings


Frequently asked questions

If you place your order now, the estimated arrival date for this product is: Sunday, Dec 7

This item is non-returnable:

Non-returnable due to Food safety reasons

View our full returns policy here.

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Top Amazon Reviews


  • THESE WORK! great supplement amount.
Size: 60 Count (Pack of 1)
I am thrilled with my experience using these Lion's Mane mushroom supplements! They have truly made a noticeable difference in my cognitive clarity and mental focus. I have been taking them for a year now, the quality of the supplement is excellent, and I feel more alert and energized throughout the day. I appreciate that it's a natural way to support brain health and boost my overall well-being. Highly recommend to anyone looking to enhance their mental performance and support their nervous system naturally! The amount of actual lions mane in these is what is suggested to actually make a difference. I absolutely notice if I miss a month. No weird after taste. ... show more
Reviewed in the United States on August 28, 2025 by Scott and Amber

  • I Absolutely Love This Supplement – Clearer Mind, Better Focus!
Size: 120 Count (Pack of 1)
Host Defense Lion’s Mane has been a total game-changer for me. I started taking it to help with focus and mental clarity—and within about a week, I noticed a real difference. My brain fog started to lift, and my ability to stay on task noticeably improved. I feel more present and mentally sharp throughout the day. What makes me feel confident is the quality and integrity behind the brand. Paul Stamets and the Host Defense team are serious about mushroom science—this isn’t some generic powder. It’s organic, sustainably grown, and made in the USA, which gives me peace of mind. The capsules are easy on the stomach, and I love that it’s a whole mushroom mycelium extract, not just isolated compounds. I’ve also found it supports my mood and reduces some of the scattered thinking I struggle with due to ADHD. If you’re looking for a natural cognitive boost that actually feels clean and sustainable, this is it. I truly love it and recommend it to anyone who wants better brain health—without the crash or side effects. ... show more
Reviewed in the United States on July 14, 2025 by Joey

  • Host Defense Lion's Mane Capsules: Nurturing Cognitive Well-Being Naturally
Size: 30 Count (Pack of 1)
The Host Defense Lion's Mane Capsules have become an integral part of my daily wellness routine, offering a natural and effective solution for promoting mental clarity, focus, and memory. This mushroom supplement, with its unflavored simplicity, stands out as a holistic approach to cognitive well-being. Mushroom Power for Cognitive Enhancement: Host Defense's Lion's Mane Capsules harness the power of Lion's Mane mushrooms, known for their potential cognitive benefits. The capsules provide a convenient and concentrated form of this natural ingredient, offering a holistic approach to nurturing mental clarity, focus, and memory. Promotes Mental Clarity: One of the standout benefits of this supplement is its ability to promote mental clarity. Regular use has resulted in a noticeable improvement in my cognitive function, creating a sense of mental sharpness and alertness that enhances my daily activities and decision-making. Enhanced Focus: The Lion's Mane Capsules have proven to be a reliable ally in enhancing focus. Whether tackling work tasks, engaging in creative pursuits, or simply navigating a busy day, the supplement contributes to a heightened ability to concentrate and stay on task. Memory Support: Memory support is a crucial aspect of cognitive well-being, and Host Defense's Lion's Mane Capsules deliver in this area. The natural properties of Lion's Mane mushrooms are believed to have neuroprotective effects, contributing to improved memory recall and cognitive function over time. Easy Incorporation into Daily Routine: The convenience of encapsulated Lion's Mane mushrooms makes it easy to incorporate into my daily routine. The unflavored nature of the capsules eliminates any taste concerns, allowing for a seamless addition to my wellness regimen without the need for flavor masking or mixing with other substances. Natural and Mushroom-Derived: What sets Host Defense apart is its commitment to providing natural, mushroom-derived supplements. The capsules contain pure Lion's Mane mushroom mycelium and fruitbodies, free from unnecessary additives or fillers. This dedication to natural ingredients aligns with my preference for clean and authentic wellness solutions. Trusted Brand and Quality Assurance: Host Defense has established itself as a trusted brand in the realm of mushroom supplements. The company's commitment to quality assurance, sustainable practices, and rigorous testing ensures that each capsule meets the highest standards. This reliability adds an extra layer of confidence in the effectiveness of the Lion's Mane Capsules. Unflavored Simplicity: The unflavored nature of the capsules is a welcome simplicity. It eliminates any concerns about taste preferences or flavor interactions with other supplements. The straightforward delivery of Lion's Mane benefits without added flavors aligns with the purity and authenticity of Host Defense products. Highly recommended for anyone looking to prioritize their cognitive well-being naturally. ... show more
Reviewed in the United States on January 9, 2024 by Mrs Sunshine

  • No more struggle with word finding
Size: 120 Count (Pack of 1)
Post menopausal, I struggled with word finding. It caused me tremendous anxiety because the word was right there but I couldn’t grasp it so I would scurry around for a substitute. I have been on Lions Mane for a month now and the difference is night and day. All I can say is thank you Host Defense for developing this amazing product. ... show more
Reviewed in the United States on September 15, 2025 by Sophia

  • Been a positive experience
Size: 60 Count (Pack of 1)
Giving my honest review for all the skepticals like me out there: I've been taking Lion's Mane every day for over a month now. If I talk about how I'm "feeling" it could be all placebo effect and situational changes but the real physical change I've noticed after a week of taking it is the improved quality of sleep. So I guess waking up from a good night sleep trickles down to higher energy, improved mood, better focus, and memory. Another thing is I'm a woman in my 30's with bad PMS such as depressed mood and fatigue and this supplement seems to ease the symptoms a little. Lastly, don't expect drastic changes in your mind, it's a subtle and gradual change but it's for the better. I'm starting to slowly noticing the benefits after a month of taking it. ... show more
Reviewed in the United States on September 10, 2022 by Aryan F

  • Anxiety relief
Size: 60 Count (Pack of 1)
Took in past for anxiety. Works well. I'm much calmer
Reviewed in the United States on September 22, 2025 by Satinvalentine

  • Great Stuff
Size: 60 Count (Pack of 1)
Great product! Helps with pain. Helps with memory. Wonder what else it does 😲
Reviewed in the United States on July 31, 2025 by Curtis

  • Wonderful for focus
Size: 60 Count (Pack of 1)
I have noticed a difference in my focus and mood after a couple weeks. I subscribe now.
Reviewed in the United States on September 5, 2025 by Amazon Customer

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