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Zymox Topical Hot Spot Spray for Dogs and Cats with 1% Hydrocortisone, 2oz

  • Based on 1,905 reviews
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Arrives Tuesday, Oct 20
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Features

  • Spray for dogs and cats; veterinarian-strength with 1% Hydrocortisone
  • For relief, apply directly to the skin; no need for pre-cleaning
  • Soothing no-sting formula for pet wound care and skin infections caused by germs, fungi and yeast
  • LP3 Enzyme System for relief from itchy, infected or irritated skin plus soothing aloe vera
  • Non-toxic, safe, and gentle if your pet licks the application site; promotes healthy skin

Description

Veterinarians and pet parents alike have been using ZYMOX products to successfully manage pet’s ear infections and irritated skin for more than 20 years. The ZYMOX range of pet products includes: Together, they can soothe your pets’ ear and skin problems. ZYMOX products help manage the symptoms of fungal and yeast infections without using harsh chemical ingredients. ZYMOX hot spot spray for dogs and cats promotes relief from itching, allergies and hot spots. ZYMOX Topical Spray is a Hydrocortisone-free formula for sensitive, pregnant or lactating pets. It is also available with 1% Hydrocortisone to calm irritated skin and aloe vera to soothe redness and inflammation. Our anti-itch spray for dogs and cats also soothes skin wounds and infections. The no-sting formula with the ZYMOX LP3 Enzyme System aids recovery from skin infections caused by germs, fungi and yeast. ZYMOX Spray is Ideal for use on: ZYMOX Spray is simple to use - spray onto the affected area once or twice a day, for up to seven days. Because ZYMOX hot spot spray for dogs and cats only contains safe, gentle and non-toxic ingredients, it’s safe if your inquisitive pet licks the application site. Recurrent skin infections, hot spots and irritation can lead to a distressed pet and repeat visits to your veterinarian. They can also mean repeat courses of medication, which can lead to problems with resistant bugs that don’t respond to conventional medicinal treatment. The ZYMOX LP3 Enzyme System is effective on a broad spectrum of germs, fungi and yeast that cause skin problems. Enzymes are naturally-occurring proteins, and the LP3 Enzyme System from ZYMOX helps destroy microorganisms without attacking healthy cells or irritating the skin. Enzymes don’t develop a resistance to microbes and will continue to work for your pet when they need them. There’s no need to pre-clean sore areas first. Simply spray without cleaning. The enzymes react with organic matter within the skin helping to manage infections and hot spots. ZYMOX Topical Spray includes 1% Hydrocortisone for relief from itching and inflammation. ZYMOX Topical Spray is also available without Hydrocortisone for sensitive animals, rodents, exotics, pets sensitive to Hydrocortisone and pets that are pregnant or lactating. ZYMOX Topical Spray is an all-in-one solution for infections caused by germs, fungi and yeast. Enzymes do not develop a resistance to microbes, so this spray will continue to work for your pet. The LP3 Enzyme System reacts with biological materials in the skin to form its powerful soothing properties. Simple, effective relief. Apply once or twice a day by spraying the entire affected area. There’s no need to cause fear or upset in your pet, as there’s no painful pre-cleaning necessary. Pre-cleaning and cleaning during use disrupts the biological system and will negatively affect results.

Package Dimensions ‏ : ‎ 4.8 x 2.56 x 1.81 inches; 2 ounces


Date First Available ‏ : ‎ July 20, 2011


Manufacturer ‏ : ‎ Pet King Brands


Best Sellers Rank: #6,609 in Pet Supplies (See Top 100 in Pet Supplies) #13 in Non-Prescription Dog Medications


#13 in Non-Prescription Dog Medications:


Customer Reviews: 4.5 4.5 out of 5 stars (1,905)


Frequently asked questions

If you place your order now, the estimated arrival date for this product is: Tuesday, Oct 20

This item is non-returnable:

Non-returnable due to Food safety reasons

View our full returns policy here.

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Top Amazon Reviews


  • Helps ease itching
Along with a daily gentle , hygiene routine, this product helped me get my furbaby through a rough sore that appeared on his neck . Helps stop the itch so they will stop scratching .
Reviewed in the United States on September 9, 2026 by White

  • This works!
I am a retired veterinary hospital owner. Wonderful product, inexpensive cure for most canine skin issues! It’s a basic in my medicine supplies.
Reviewed in the United States on October 11, 2026 by sandra shackelford

  • Great spray- recommend for contact allergies!
Cleared my dog’s grass allergy on chest after two days of application! No chemical smells and after it dried she was not tempted to lick it. The spray had a thick and heavy stream as well as a wide coverage area.
Reviewed in the United States on August 7, 2026 by Miranda Zuelke

  • It works
It worked really well for our little girl.
Reviewed in the United States on September 17, 2026 by Amazon Customer

  • works fast
works well on the skin
Reviewed in the United States on September 11, 2026 by don case

  • Itch Relief
For dogs but I spray it on bug bites for itch relief
Reviewed in the United States on August 18, 2026 by Kindle Customer

  • Buy It
Worked quickly on my dogs hot spots. Better than any creams I've tried.
Reviewed in the United States on August 19, 2026 by Nutsy

  • Not worth it. Shop around.
My advice is only purchase this for very small hotspots that are uncommon in your dog. My dog gets large ones often and this bottle is so small, several squirts and it was completely gone. It’s not for problem skin dogs and barely helped b/c it only treated hot spot for 2 days and was empty. VERY EXPENSIVE for the amount of product in bottle. ... show more
Reviewed in the United States on February 8, 2026 by CAROL SILVESTRI

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