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THORNE 5-HTP, 100 mg 5-Hydroxytryptophan & Active Vitamin B6, 90 Capsules

Based on 1,042 reviews
Condition: New
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$39.00

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Availability: Only 5 left in stock, order soon!
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Arrives Oct 28 – Oct 29
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At a glance

Condition
New
Model
SA503-R
Dimensions
1.83 x 1.83 x 3.22 in
Weight
22.68 g
Color
Red
Item Form
Capsule
Diet Type
Vegetarian

Features 5

  • Sleep: Supports restful sleep*
  • Stress: Nutritional support for stress*
  • Cravings: Helps decrease sugar cravings*
  • Positivity: Supports a healthy outlook*

Description

5-Hydroxytryptophan Basic Nutrients Creatine Magnesium Glycinate Super EPA Berberine Magnesium Bisglycinate What makes Thorne supplements high quality? Thorne produces high-quality supplements through rigorous testing, well-researched ingredient sourcing, and strict manufacturing standards. We avoid unnecessary additives, binders, and fillers that may interfere with nutrient absorption. How does Thorne test its supplements for quality? To confirm the purity of our ingredients, the potency of our formulas, and the absence of all contaminants, we carry out a minimum of four rounds of testing on every product we manufacture. 100+ Thorne employees are dedicated to ensuring quality. Are Thorne supplements clinically tested and safe? Thorne partners with researchers and conducts clinical trials to support the efficacy of our products. Our team of doctors and medical experts substantiate each ingredient in every formula based on extensive clinical research and medical literature. Why are Thorne products more expensive than other supplements? When it comes to the health of our customers, we never settle. Thorne products may be priced higher than some others because of our commitment to quality at every step. We don’t simply meet the standard in dietary supplements — we set the standard. Where are Thorne supplements made and where are the ingredients sourced from? Located in South Carolina, Thorne manufactures supplements in the USA using globally sourced ingredients. When it comes to ingredient sourcing, we seek out only the highest-quality ingredients, selecting each one for its purity and effectiveness.

Specs 24

Product Dimensions 1.83 x 1.83 x 3.22 inches; 0.8 ounces
Manufacturer Thorne Research
Brand Name THORNE
Primary Supplement Type 5-HTP
Item Form Capsule
Diet Type Vegetarian
Product Benefits Emotional Wellness, Sleep Support*
Age Range Description Adult

Frequently asked questions

If you place your order now, the estimated arrival date for this product is: Oct 28 – Oct 29

This item is non-returnable:

Non-returnable due to Food safety reasons

View our full returns policy here.

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Top Amazon Reviews


Works
Easy to use. Helps support my adhd medication. I noticed a difference.
Reviewed in the United States on August 14, 2026 by Jamie Hussey

Really helps with depression and anxiety.
I have been tapering from 60mg of Cymbalta (I'm down to about 2.5mg now) for almost 3 years. It's been totally brutal and horrible despite how slow I have taken it. I've been taking 5htp since I got down to about 25mg of Cymbalta. THERE IS NO WAY I would ever make it through the taper without taking this 5htp. Not all 5htp brands are equal. This is the best one I have found, probably because it has the methylated B-6, and because Thorne is a generally a good quality brand to begin with. Cymbalta is an SNRI- the 5htp only boosts serotonin and not norepinephrine (just a side note, on the off chance that someone reading this is tapering off an SNRI), but still, I can't emphasize enough how much it has helped me. There are other supplements one can take to help with Norepinephrine...I haven't found one that works for me yet, but everyone is different. Also, other vitamins I take, such as vitamin d, methylated b12, and methylated b complex, have been game changers. My son (17) also has depression and anxiety. He takes this 5htp, a super high quality fish oil, vitamin D, methylated vitamin b complex, and a multivitamin. He is literally two different people depending on whether he is taking his supplements regularly (we're on good streak currently, he's been taking them nearly every day for over two months and is feeling great). I almost never write reviews, but something told me to tonight. Who knows, maybe it will help someone. :) ... show more
Reviewed in the United States on February 20, 2021 by Sara Hagen

Sleep
Two capsules at bedtime help me sleep.
Reviewed in the United States on September 26, 2026 by VV

Rave party recovery supplement! Serotonin booster
This stuff is amazing after a night of raving and partying hard all night long. Helps restore serotonin levels.
Reviewed in the United States on September 3, 2026 by Jonathan Gray

works
good
Reviewed in the United States on September 3, 2026 by Joseph Patrick Fair

Great supplement for sleep!
My sister and I have suffered from stress sleep deprivation for years. I’ve tried all the prescribed and OTC sleep aids, nothing works. My sister put her foot down and asked our doctor what VITAMINS there are that support sleep and stress and finally, 5-htp was mentioned. My husband and I have been using Thorne supps for years so I was very excited to see they had this product. I bought it immediately and I am elated to share that 2 months later, I am sleeping like a BABY!!! Like a freakin BABY!!! I take it 45 mins before I want to be asleep and I don’t even make it through an episode of my show before I’m knocked out. I especially love the fact that it doesn’t make me feel like a zombie when I wake up. In fact, I now wake up on my first alarm. No more snoozing until the last minute. My boss loves that I’m taking 5-htp too now that I’m regularly on time to work! ... show more
Reviewed in the United States on December 29, 2025 by Leanna Bortle

Trusted brand
Excellent product, my doctor recommended.
Reviewed in the United States on August 18, 2026 by BarbaraW

Be careful if you use this and look for these side effects. Stop using if you get them, they fade.
Bad side affects after one week of use, worse at three weeks and stopped using it. Side effects include Hyperness, insomnia, depression.
Reviewed in the United States on August 14, 2026 by Joel
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