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Douxo

Douxo S3 Pyo Shampoo, Contains 3% Chlorhexidine & 0.5% Ophytrium, Antiseptic & Hydrating, For Bacterial or Yeast Skin Infections, For Dogs and Cats, 6.7 fl. oz. (200mL)

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Availability: In Stock.
Fulfilled by Amazon
Arrives Monday, Jul 27
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Size: 6.7 oz


Features

  • #1 non-prescription topical brand used and recommended by U.S. veterinarians for dogs and cats with infections/inflammatory dermatological disease
  • Proven to disinfect, hydrate and help support the skin's ecosystem and reduce yeast counts in 7 days
  • Contains ophytrium, a purified natural ingredient that helps support the skins physical barrier for supple hydrated skin and helps soothe irritated skin
  • Free from soaps, sulfates, parabens, dyes and nanoparticles
  • For best results use with the DOUXO PYO Mousse

Description

Soothes, cleans and strengthens the skin barrier. Moisturizes and detangles the fur to leave the coat soft and shiny. DOUXO is the 1 non-prescription topical brand used and recommended by U.S. veterinarians for treatment of dogs and cats with inflammatory dermatological diseases.

Brand: Douxo


Scent: Coconut, Vanilla


Product Benefits: Soothing,Moisturizing,Detangle


Recommended Uses For Product: For Bacterial or Yeast Skin Infections For Dogs and Cats


Material Type Free: Paraben Free,Sulfate Free


Package Dimensions ‏ : ‎ 5.94 x 2.48 x 1.81 inches; 6.7 ounces


Item model number ‏ : ‎ D98410M


Date First Available ‏ : ‎ May 5, 2021


Manufacturer ‏ : ‎ Douxo S3


Best Sellers Rank: #385 in Pet Supplies (See Top 100 in Pet Supplies) #3 in Dog Shampoos


#3 in Dog Shampoos:


Customer Reviews: 4.7 4.7 out of 5 stars (7,530)


Brand Name: Douxo


UPC: 850002593426


Manufacturer: Douxo S3


Manufacturer Part Number: D98410M


Model Number: D98410M


Item Weight: 6.7 Ounces


Included Components: Shampoo


Unit Count: 1 Count


Item Type Name: Shampoos & Conditioners


Scent Name: Coconut, Vanilla


Product Benefits: Soothing,Moisturizing,Detangle


Item Form: Liquid


Target Species: dog, cat


Pet Type: Cat, Dog


Recommended Uses For Product: For Bacterial or Yeast Skin Infections For Dogs and Cats


Allergen Information: Hypoallergenic


Material Type Free: Paraben Free,Sulfate Free


Special Ingredients: ophytrium


Liquid Volume: 6.7 Fluid Ounces


Frequently asked questions

If you place your order now, the estimated arrival date for this product is: Monday, Jul 27

Yes, absolutely! You may return this product for a full refund within 30 days of receiving it.

To initiate a return, please visit our Returns Center.

View our full returns policy here.

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Top Amazon Reviews

    • Miracle in a bottle!
Size: 16.9 oz
My senior French Bulldog recently developed very dry, brittle fur that felt like hay/straw and was shedding like crazy. Her skin was also VERY greasy, smelly, and slightly bumpy, even just a week after bathing. She also had dried skin flakes that looked like dandruff. In just one wash her fur was noticeably soft and conditioned; her skin was supple and moisturized; and the best part — no more shedding, dandruff, greasy skin or odor! The bumps on her skin subsided and were no longer inflamed. She also smells amazing! A light coconut scent that is soft and subtle and not overwhelming. We used to use Douxo S3 PYO 10 yrs ago when she was a puppy but stopped after they changed formulas, afraid that it wouldn’t be the same. Boy I wish we hadn’t. For the first time ever, my senior puppy had zoomies after her bath! This will be our go-to shampoo for flare-ups from now on! ... show more
Reviewed in the United States on March 25, 2026 by _
    • Amazing product, good stuff!
Size: 6.7 oz
My Maltese has always had skin allergies, but as he’s gotten older it has gotten worse, especially with yeast on his skin. This shampoo has been the best product I have ever used (I have tried several) and I am going to also let my vet know about it. It took all the stickies off his fur and skin and made his fur shiny and soft again. He’s no longer scratching himself to a point where he makes his skin bleed and he looks much more comfortable.. Amazing product! ... show more
Reviewed in the United States on April 18, 2026 by Azita C.
    • 5 Stars - HIGHLY Recommend! Works Amazing for Allergies!
Size: 16.9 oz
Hands down the best dog shampoo I've ever used.y American Pitbull is allergic to everything,I even had him undergo the prick test with the Dermatologist & he's allergic to 40 out of 46 items tested for. So his skin is always broken out, even while doing the Allergy Immunotherapy injections, I'm averaging every 3rd day on giving him another bath & this shampoo is helping him so much! He will be completely broken out, red bumps & hives all over his body, I'll give him a bath & within a few hours, or by the next morning (since I usually bathe right before bed) his skin has significantly improved, half the bumps will be gone, most of the hives are completely gone & the redness is nonexistent! The smell is really great as well, it's a lighter scent, I don't smell any chemicals or any of the normal medicated smell at all & it's light enough you can smell it on your pup if you're up close, but otherwise it's not noticeable. The formula is decently thick, it's not runny at all, but it suds up so great as well - another huge thing most medicated shampoos don't do! You also only need a small amount, it actually advises how much to use on the bottle depending on how large your dog is, but it's so easy to suds up, that you don't need much at all. I have a 64lbs Pitbull & I only use 2 pumps on his whole back, 1 on each side & 1 pump on each leg & that's about it. So the cost is a bit expensive, but it lasts forever with how little you need & with how well it works, its 100% worth it. The pump works great, it has the locking mechanism when you turn the pump to the side, so you don't have to worry about it leaking, we transport it every weekend to our MIL's house, and I just throw it in the bag, never leaked before, you don't have to worry about it. I can't recommend this shampoo enough or stress how well its been working for our 4 dogs! ... show more
Reviewed in the United States on September 15, 2025 by Heather
    • Amazing Stuff - fixed my dog's skin issues!
Size: 6.7 oz
My dog had maybe a yeast infection, skin allergies... idk. He had scabs and dandruff all over his back and belly, and lots of discoloration on his belly which came out of nowhere, He was constantly itching and I felt so bad for him ): I decided to look into it and found people with similar issues. So, with recommendations, I found this shampoo, and also switched his dog food to a better one. With the switch of his dog food, I can't say that one or the other fixed his skin, or both was the solution, but either way, his skin and coat has made a DRASTIC change in just one month. I have been washing him every 3-4 days with this shampoo for a month now, scrubbing him very well and leaving it to sit on him for 5-10 mins. He hates baths but it's what we have to do! This stuff smells great, it suds up and has a nice lather, rinses well, and leaves his coat feeling soft and clean! I can't complain at all. Yes it is pricey as heck, but if it works how can I complain. when I was researching on the internet for my dog's specific issues, I saw people with similar issues say their dog had a yeast infection, and when they took their dog to the vet, this is what their vet recommended! This is what made me take the jump on the purchase and I was not disappointed. ... show more
Reviewed in the United States on November 3, 2025 by Taylor S
    • Seems to help, just slower than expected
Size: 6.7 oz
I’ve been using this on my 2-year-old Golden Retriever who developed a skin rash and after about 3 weeks I can say it does seem to be helping. The redness has gone down a bit and overall his skin looks calmer, so it’s definitely doing something. That said, I was expecting more noticeable results by now. The improvement feels a bit slower than I hoped, especially given the price. Overall it’s a solid product and I’ll keep using it, but just be aware it may take some time to see stronger results. ... show more
Reviewed in the United States on April 1, 2026 by Christine S
    • Great for yeasty dogs!
Size: 6.7 oz
My frenchie has the worst skin allergies. She is always yeasty. This is the best shampoo for her. We also get the wipes and the foam. As much as she HATES baths, she’s not so itchy after using. 10/10 recommend!!!
Reviewed in the United States on April 29, 2026 by Briana A.
    • Very soothing for my dog
Size: 6.7 oz
The shampoo really helps my dog. So glad I found it. The smell is nice, it rinses out clean, and it helps with my dogs, skin irritation.
Reviewed in the United States on March 25, 2026 by Know

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