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Systane

Systane PRO PF Lubricating Eye Drops for Dry Eyes, 2 x 10 mL, Preservative Free with Hyaluronate, Triple-Action Formula to Hydrate, Restore & Protect, Multi-Dose Bottle

  • Based on 2,666 reviews
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Availability: Only 6 left in stock, order soon!
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Arrives Aug 16 – Aug 18
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Features

  • Triple-Action Dry Eye Relief: Systane PRO Preservative Free Lubricant Eye Drops hydrate, restore, and protect dry eyes for up to 12 hours of relief. This triple-action formula provides rapid, continued relief from ocular discomfort due to environmental causes such as wind and sun
  • Long-Lasting Hydration: Provides temporary relief from burning and irritation due to dryness of the eye. Systane PRO with Hyaluronate lubricating eye drops are formulated to support extended hydration for dry eye relief
  • Tear Evaporation Protection: Hydrating eye drops helps lock in moisture and reduce tear evaporation
  • Preservative-Free Formula: The gentle, preservative-free formula is suitable for sensitive eyes and helps prevent further dryness and irritation. It offers multi-symptom dry eye relief and may be used with soft contact lenses, but it is not a rewetting drop
  • Trusted Brand, Convenient Design: Systane is a trusted name in eye care, recommended by eye care professionals for reliable dry eye relief. The multi-dose easy-application bottle offers on-the-go hydration, keeping eyes refreshed and moisturized wherever your day takes you

Description

Systane PRO PF Multi-Dose Eye Lubricant Drops for Dry Eyes, Hydrate, Restore & ProtectExperience long-lasting comfort with Systane PRO PF Preservative Free Lubricant Eye Drops, a triple-action formula that hydrates, restores, and protects dry eyes for up to 12 hours of dry eye relief. Helps soothe irritation caused by dryness or environmental factors like wind and sun, this formula helps lock in moisture to reduce tear evaporation, and provides long lasting hydration for dry, irritated eyes.Formulated with the active ingredient Propylene Glycol to lubricate and soothe dry eyes, these drops help lock in moisture and support extended hydration.Systane PRO, with lipids, restores the tear film to prevent further evaporation, helping to ensure your eyes stay comfortably moisturized. Ideal for sensitive eyes, the preservative- free formula provides multi-symptom relief without harsh ingredients or irritation.Systane is a trusted name in eye care, recommended by eye care professionals for reliable dry eye relief. The convenient multi-dose bottle is suitable for daily, on-the-go use, helping you keep your eyes refreshed, hydrated, and protected wherever your day takes you. Safe for use with soft contact lenses (not a rewetting drop).

Product Dimensions ‏ : ‎ 1.25 x 2.56 x 4.25 inches; 0.68 ounces


Date First Available ‏ : ‎ February 1, 2025


Manufacturer ‏ : ‎ Alcon Laboratories


Best Sellers Rank: #9,464 in Health & Household (See Top 100 in Health & Household) #17 in Dry Eye Relief Products #203 in Vision Products


#17 in Dry Eye Relief Products:


#203 in Vision Products:


Customer Reviews: 4.6 4.6 out of 5 stars (2,666)


Brand Name: Systane


Product Benefits: Eye Care


Specific Uses For Product: Dry Eye


Active Ingredients: propylene glycol


Item Form: Liquid


Age Range Description: Adult


Target Audience: Unisex-Adults


Dosage Form: Drops


Global Trade Identification Number: 57


Manufacturer: Alcon Laboratories


UPC: 300653290057


Item Weight: 0.68 Ounces


Item Dimensions: 1.25 x 2.56 x 4.25 inches


Number of Items: 1


Unit Count: 2 Count


Net Content Count: 2 Bottle


Additional Features: Fast-Acting


Frequently asked questions

If you place your order now, the estimated arrival date for this product is: Aug 16 – Aug 18

This item is non-returnable:

Non-returnable due to Food safety reasons

View our full returns policy here.

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Similar Products

Top Amazon Reviews

    • Excellent preservative-free drops that actually last
I’ve tried quite a few eye drops for dry, irritated eyes, and these Systane PRO PF drops are easily one of the best. The fact that they’re preservative-free is a huge plus, especially if you use drops multiple times a day or have sensitive eyes. What really stands out is how long the relief lasts. Unlike basic drops that wear off quickly, these feel more moisturizing and keep my eyes comfortable for hours. The “triple action” formula seems to make a difference, it doesn’t just soothe instantly but helps prevent dryness from coming back too fast. I also appreciate the multi-dose bottle design. You get the convenience of a regular bottle without worrying about preservatives, which is hard to find. The drops come out easily and consistently, and the bottle feels clean and well-designed. The 2-pack is a great value too, I keep one at home and one in my bag. Overall, if you deal with dry eye, screen fatigue, or irritation, these are absolutely worth trying. Reliable, gentle, and effective. ... show more
Reviewed in the United States on April 3, 2026 by Jay Kekoa
    • The Unblinking Solution
Dry eye is not a glamorous complaint. It is the affliction of too many screens, too little sleep, and the particular cruelty of forced air heating. You reach for a bottle. You tilt your head back. And then you get that horrible blur, the one that makes you look like you have been crying over a spreadsheet. Systane PRO PF understands the assignment. The "PF" stands for preservative free, which matters if you use these more than twice a day, and let us be honest, you probably do. They come in single use vials, which feels wasteful until you remember that a multi dose bottle with preservatives is essentially pickling your eyeballs. The drop itself is thick but not goopy. It lands softly. There is no sting, no medicinal burn, just a quiet, immediate sense of relief that lasts a respectable few hours. Not the greasy film of cheaper brands. Not the vanishing act of the watery ones. A proper lubricating drop that actually lets you blink without feeling like sandpaper under the lid. ... show more
Reviewed in the United States on May 25, 2026 by Bernie Lomax
    • Unbelievably good eye drops
Didn't think I'd be leaving a passionate review about eye drops, but maybe other dry eye sufferers will understand why I feel the need to! I've tried a few brands and formulas for eye drops and none have even come close to the relief I feel using Systane's. I used the complete formula for a long while and was more than happy to apply the eye drops 3-4 times a day, but I noticed they came out with the Pro version and decided to try it. I'm so glad I did. I have no idea what they changed in the formula, but it lasts significantly longer. On days where I have very heavy screen use, I might need to apply twice in a day. Over the weekend, I can apply it once on Saturday morning and not need it again until I work again on Monday. To compare, most other brands I tried I'd need to apply every 2 hours - and even then, they only provided about half the relief that these provide me. The price is high, but the drops last much longer so it costs less in the long run compared to any other product, plus it works SO much better. It's seriously life changing. I hope it works as well for you as it does for me! ... show more
Reviewed in the United States on April 20, 2026 by V
    • Good product but the bottle design could be better
This product is effective and it does help. But the design of the bottle isn't great. I miss my eyes, even though I try and position the blue dot correctly, and the pressure required to dispense a drop makes too much come out. But it does help my dry eyes, and I can use it fewer times a day than other Systane drops. ... show more
Reviewed in the United States on March 27, 2026 by Patti
    • Effective Relief for Dry Eyes, but Expect Brief Blurriness After Use
I spend long hours in front of screens and started dealing with frequent dry, irritated eyes. This Systane product came in highly recommended for something strong enough to actually relieve discomfort, but gentle enough for regular use without preservatives. Been using these drops consistently for over a year now, usually once or twice a day, especially after long work sessions. The soothing effect is noticeable almost immediately. Within seconds, my eyes feel more comfortable and less strained, which makes it easier to keep working or reading. They feel effective without causing stinging or irritation, and I haven’t had any negative skin reactions around the eyes, even with frequent use. For me, right after applying the drops, my vision gets slightly blurry for the first few minutes. It clears up on its own, but it’s something to plan around, especially if you need to look at a screen or drive right away. Another minor issue is the bottle design. Some bottles don’t open smoothly, and when squeezing, it’s easy to dispense more drops than intended. That can be wasteful, especially for a product that isn’t cheap. These feel more substantial than basic artificial tears. They don’t just coat the eye briefly; the relief lasts a reasonable amount of time. Because of the preservative-free formula, I feel comfortable using them regularly, which helps justify the price, though I do wish the value for money were slightly better given the packaging issues. ... show more
Reviewed in the United States on January 6, 2026 by Stan Ohis
    • Very Soothing Relief
These eye drops feel gentle and provide quick relief for dry eyes. The preservative-free formula is great for sensitive eyes, and they help keep eyes comfortable for hours. Very effective and easy to use!
Reviewed in the United States on May 23, 2026 by leili Hatami
    • Excellent choice
I bought these because my eye doctor recommended the brand and the Systane website ranked these as some of their best. I really like the bottle because I can just focus on the blue dot and not miss my eye. So, easy to use.I feel like I have to moisturize less using these cuz they're hydrating. Very effective I guess you could say. They feel fine, zero burn. Big bottle with plenty of drops. Only downside is my eyes can be a bit crusty after multiple uses. ... show more
Reviewed in the United States on March 4, 2026 by Jillian
    • Okay but inefficient
More difficult to use than earlier versions. Difficult to get liquid to drop.
Reviewed in the United States on June 1, 2026 by Dotgirl

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