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Systane Hydration Lubricating & Hydrating Eye Drops, 0.34 fl oz, Pack of 1

  • Based on 3,828 reviews
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Availability: In Stock.
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Arrives Saturday, Sep 26
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Size: 0.34 Fl Oz (Pack of 1)


Features

  • Hydrating Relief for Dry, Irritated Eyes: Systane HYDRATION Preservative-Free Lubricant Eye Drops provide long-lasting hydration for dry, tired, or irritated eyes, including those with aqueous-deficient dry eye. Helps ease dryness that can be caused by environmental stressors, or prolonged screen use
  • Long-Lasting Dry Eye Relief: Combines a Lubricant, HP-Guar and Hyaluronic Acid. This advanced hydration formula is suitable for post surgical patients, aqueous dry eye & moderate dry eye sufferers seeking dependable everyday dry eye relief
  • For Eyes Sensitive to Preservatives: Systane Hydration Preservative-Free Eye Drops are formulated to be gentle on eyes sensitive to preservatives and can be used throughout the day as needed for those who spend long hours on computers, mobiles, and laptops. Suitable for use with soft contact lenses, but it is not a rewetting drop
  • Easy, Sterile Dosing: The preservative-free multi-dose bottle helps ensure hygienic application and reduces the risk of spillage with its ergonomic design. Instill 12 drops as needed throughout your day, whenever needed
  • Trusted Brand, Convenient Design: Systane is a trusted name in eye care, recommended by eye care professionals for reliable dry eye relief.

Description

Eye Drops for Dry Eyes, Long-Lasting Dry Eye ReliefGet long-lasting dry eye relief with Systane HYDRATION Preservative Free Lubricant Eye Drops for Dry Eyes, designed to deliver advanced dual-action hydration for moderate dry eye sufferers.Formulated with a unique combination of a lubricant, HP-Guar & Hyaluronic Acid, these dry eye drops are suitable for post surgical patients to provide soothing hydration for aqueous-deficient dry eyes, reducing irritation, dryness. Comes in a convenient multi-dose bottle, a hygienic, easy-to-use experience. Suitable for use with soft contact lenses, not a rewetting drop, this solution provides hydration whenever your eyes need it most. Systane is a trusted name in eye care, recommended by eye care professionals for reliable dry eye relief.

Product Dimensions ‏ : ‎ 1.25 x 1.75 x 3.88 inches; 0.34 ounces


Item model number ‏ : ‎ 0065151006


Date First Available ‏ : ‎ February 1, 2021


Best Sellers Rank: #14,916 in Health & Household (See Top 100 in Health & Household) #57 in Moisturizing Eye Drops #333 in Vision Products


#57 in Moisturizing Eye Drops:


#333 in Vision Products:


Customer Reviews: 4.6 4.6 out of 5 stars (3,828)


Brand Name: Systane


Product Benefits: Hydration, Soothing


Specific Uses For Product: Dry Eye


Active Ingredients: Aspirin


Item Form: Drop


Age Range Description: Adult


Target Use Body Part: Eyes


Container Type: droplet


Flavor: Unflavored / No taste; ophthalmic solution only.


Package Type Name: R


Model Number: 0065151006


Dosage Form: Drops


Global Trade Identification Number: 65


Item Highlight: Combines HP-Guar & Hyaluronic Acid, Multi-Dose Eye Drops for Irritation & Dryness, Moisturizing & Soothing


UPC: 300651510065


Manufacturer Part Number: 0065151006


Item Weight: 9.66 g


Item Dimensions: 1.25 x 1.75 x 3.88 inches


Number of Items: 1


Unit Count: 1 Count


Additional Features: Fast-Acting


Frequently asked questions

If you place your order now, the estimated arrival date for this product is: Saturday, Sep 26

This item is non-returnable:

Non-returnable due to Food safety reasons

View our full returns policy here.

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Top Amazon Reviews


  • Amazingly hydrating for contacts
As a person with chronic dry eye, these drops are a lifesaver. The hydration lasts all day and is safe for my contact lenses.
Reviewed in the United States on September 10, 2026 by Glow & Nest

  • Great for Dry Eyes - Long-Lasting Relief
I’ve used these drops only twice so far, and I’m already getting good results. The lubrication feels strong and lasts longer compared to other eye drops I’ve tried. I was a bit concerned about the bottle because some reviews mentioned that it’s hard to squeeze out the drops. However, I didn’t have any issues. The blue tip makes it easy to see the drop forming, so you can position it properly and let it fall into your eye. Very simple to use. Just make sure to shake the bottle before using it, as mentioned in the directions. My routine now is to use the drops early in the morning and again in the afternoon whenever I need extra moisture. Trust me, it's good for dry eyes, especially people like me who spend a lot of time in front of the screen. I also like that this is preservative-free (PF), which is better for your eyes if you use drops frequently. So far, I’m very happy with this product as a new user, and I will definitely continue using it. Highly recommended. ... show more
Reviewed in the United States on February 27, 2026 by Lewis

  • Very good eye drops!
I had chronic dry eye for about a year. The drops my doctor recommended eased it but I had to use them multiple times per day. These, I only needed twice, once in the morning and before I went to bed. After using them for a few months, I no longer needed them daily. I still used them occasionally, though. Now my eyes are getting bad again so I will definitely be using these! They are a serum consistency, so really coat your eyes & stays with you to soothe the irritation. The only things I don't like is the shape of the dropper; it's kind of difficult to tell where the drops are coming out when you're trying to put it in your eyes. Also, sometimes, towards the last of the bottle, the dropper gets clogged or gummed up because of the consistency & then the last of the drops are wasted. I'll be honest, if there is a lot left, I sterilize a needle to get it opened up. I don't like doing that, even though I sterilize, the needle because it's just not sanitary, but this stuff costs too much to waste very much of it. The quality of the eye drops is definitely worth the trouble & $. I highly recommend trying these for chronic dry eyes or just occasional use. ... show more
Reviewed in the United States on October 19, 2024 by Traceywolf 2

  • Good
Good
Reviewed in the United States on August 22, 2026 by mareyam

  • Relief in a tiny bottle!
I’ve been dealing with dry, irritated eyes—especially after long hours on the computer or in dry climates—and these Systane Hydration PF drops have truly made a difference. I love that they’re preservative-free, which feels gentler on my eyes, especially when I need to use them multiple times a day. The drops are soothing without being too thick or goopy, and they don’t leave that filmy blur some other brands do. Just a couple drops and my eyes feel refreshed and comfortable again. The bottle is easy to use and compact enough to carry in my bag. If you have sensitive or dry eyes, I’d definitely recommend giving these a try. It is a bit more expensive than some others, but for me, the comfort and relief are worth it. ... show more
Reviewed in the United States on May 12, 2025 by shjen

  • The OG of eyedrops ~
These are the best eye drops I've ever used and I've tried them all. 58-yo female suffering from dry eye, technology (multiple screens all day long) - coupled with a stressful job all pointed to a severe case of dry eyes which induced microscopic abrasions on my eyes. Went to a really good UCLA eye doc and he put my eyeball pics up on the screen and turned in his chair to me and said, "what do you do for a living?" I love it went a doctor is so good that they ask other symptomatic questions and work together to get at what might be going on. He said that blink-data on those in high-stress situations can exacerbate dry eye, as can age ... so apparently I fit the bill for all of it. Older woman in tech, parsing multiple screens all day and night long under constant deadline... not blinking enough. Never knew any of this. LOVE intelligent information. Elevated my eyedrop game to PRESERVATIVE FREE Systane Hydration PF and yes they are a little thicker drop. I have to take a 4-5 minute break for them to settle in before my eyes fully clear again, but it's a wonderful break, these make my eyes exhale and feel SO good. Not think or gummy like some of those nighttime gels, not like that, just thicker than regular eye drops. PS read the reviews on BAK eyedrop preservatives... I'm never going back to preservative drops. I love these, they're not cheap, but I use drops 4-5x a day and these are the best. jb ... show more
Reviewed in the United States on March 27, 2022 by Jb

  • Good lubricant/portability.
Love the portability, its nice not needing to carry around small individual containers for each use in your pocket and around the house. This specific one (lubricant quality wise) i find works best however the bottle design/dropper could be improved. The refresh bottle design is bette with the exeption however that i do like that this one you can twist the cap on and off feels more secured than the refresh one however with this one no matter how careful you are and ligthtly you squeeze i aways get like 1 or 2 extra drops coming down my face or in the eyes. Wish only one drop came out as intented. Its not good to overly lubricate because you wash out your natural oils when flooding the eyes with too much. So while the refresh one has a better bottle design because typically one drop comes out as intented Systanes lubricant is superior if your dry eyes require it. Just tricky trying to only get one drop in there and in most cases you will probably get 2 drops instead of 1. ... show more
Reviewed in the United States on January 20, 2023 by Chris

  • Hands down, the best
I was diagnosed with severe DES 25+ years ago, and have tried every optical lubricant there is. This blue box preservative free Systane is the best I've ever used, and have been using it for years. I am so pleased it's now available in a bottle, as the little vials have become increasingly difficult to use as my fine motor control has declined with age. My order was shipped within 24 hours of my order, though it took our dear USPS three weeks to deliver it to me. ... show more
Reviewed in the United States on August 22, 2026 by M. E. Jones

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