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Differin

Differin Acne Face Wash, 5% Benzoyl Peroxide Daily Cleanser, 4oz

  • Based on 13,686 reviews
Condition: New
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Availability: In Stock.
Fulfilled by Amazon
Arrives Oct 25 – Oct 26
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Size: 4 Fl Oz (Pack of 1)


Features

  • TARGET ACNE: Penetrates deep into pores with 5% benzoyl peroxide with less irritation & dryness
  • KEY INGREDIENTS: 5% benzoyl peroxide that can effectively target and treat acne
  • HOW TO USE: Apply to dampened skin and gently massage, rinse thoroughly with warm water
  • DERMATOLOGIST-DEVELOPED: Can be used to effectively treat acne or maskne caused by wearing face masks or facial coverings

Description

Differin Daily Deep Cleanser was developed by dermatologists and is effective without being abrasive. That means you get the clearer skin you want, with less redness and irritation. This unique, dual-action micronized formula works deep in pores to absorb excess oil while releasing a gentle moisturizer that won't clog pores. Differin Daily Deep Cleanser was formulated to be used as a part of your daily skincare routine, making it easy to incorporate this deep clean into your regimen, however it's formula does include benzoyl peroxide. Using more than one acne medication with Differin Gel is not recommended as it may cause irritation.

Product Dimensions ‏ : ‎ 2.38 x 2.38 x 6.5 inches; 4 pounds


Item model number ‏ : ‎ 0299.460600


UPC ‏ : ‎


Manufacturer ‏ : ‎ Galderma Laboratories, Inc


Best Sellers Rank: #1,239 in Beauty & Personal Care (See Top 100 in Beauty & Personal Care) #27 in Facial Cleansing Washes


#27 in Facial Cleansing Washes:


Customer Reviews: 4.5 4.5 out of 5 stars (13,686)


Scent Name: Unscented


Skin Type: Acne-Prone, Oily, Sensitive


Product Benefits: Non Comodogenic


Additional Features: Non Comedogenic


Active Ingredients: Benzoyl Peroxide 5%, benzoyl_peroxide


Item Form: Gel


Special Ingredients: Benzoyl Peroxide


Target Use Body Part: Face


Container Type: Bottle


Recommended Uses For Product: Face


Package Type Name: Bottle


Skin Cleaning Agent Use: Facial Cleanser


Item Weight: 4 pounds


Item Dimensions: 2.38 x 2.38 x 6.5 inches


Package Quantity: 1


Number of Items: 1


Unit Count: 4 Fluid Ounces


Net Content Weight: 4 ounces, 5.8 pounds


Net Content Volume: 4 fluid ounces


Brand Name: Differin


Age Range Description: Adult


Model Name: Acne Face Wash


Item Highlight: Gentle Acne Cleanser, Clears Breakouts, Sensitive Skin Safe, Benzoyl Peroxide Formula, Daily Use, 4 Oz


Global Trade Identification Number: 09


UPC: 302994606009


Manufacturer: Galderma Laboratories, Inc


Model Number: 0299.460600


Manufacturer Part Number: 60600


Material Features: Moisturizing


Color: white


Frequently asked questions

If you place your order now, the estimated arrival date for this product is: Oct 25 – Oct 26

Yes, absolutely! You may return this product for a full refund within 30 days of receiving it.

To initiate a return, please visit our Returns Center.

View our full returns policy here.

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Top Amazon Reviews

    • Great product for acne
Size: 4 Fl Oz (Pack of 1)
I really like this stuff. Second time buying it and it’s worth the price. I have suffered from acne in my 20s and has been the one thing that has helped control my acne even after being on Accutane. It does dry the skin and can irritate it if you use it too much so start slow but I recommend it to everyone ... show more
Reviewed in the United States on August 20, 2026 by Taylor Mohler
    • The only product I use for my acne outbreaks
Size: 4 Fl Oz (Pack of 1)
I work outside a lot, so I am constantly getting dirty and sweaty. I am also pretty prone to acne popping up at the worst time. I can use this product and within 24 hours my outbreaks are mostly cleared up. My face feels smoother and less gritty from clogged pores, and my skin doesn't feel dried out either. My teenage son also uses this product and says it helps his acne as well. This 4 oz size bottle usually lasts the two of us several weeks. A little goes a long ways. Great product, highly recommend. ... show more
Reviewed in the United States on August 13, 2026 by Amazon Customer
    • Active with acne
Size: 4 Fl Oz (Pack of 1)
I’ve been using the Differin Acne Face Wash with 5% Benzoyl Peroxide every day, and I’m really happy with the results. It leaves my skin feeling clean and refreshed without feeling overly dry. After a couple of weeks, I noticed fewer breakouts and my skin looked clearer and smoother. The cleanser has a creamy texture, rinses off easily, and works well as part of my daily skincare routine. If you’re looking for an effective acne cleanser that helps keep blemishes under control, I definitely recommend giving this one a try! ... show more
Reviewed in the United States on July 23, 2026 by WL
    • Benzoyl Peroxide-based
Size: 4 Fl Oz (Pack of 1)
Differin Acne Cleanser is one of the best facial treatments that I've used. I've had acne since I was about 13, and I'm 18 now. Throughout those five years, I have used alcohol-based cleansing pads, Proactive, and just regular hand soap products, none of which achieve the success of Differin. I have been using Differin Acne Cleansing for about a year now, and although it took my skin a couple of days to make the switch from different products, this treatment has decreased the number of breakouts I used to have, the redness in my face, and has just overall improved my skin. Differin Acne Cleanser is a Benzoyl Peroxide-based acne treatment, which is known to be one of the better products to use when treating acne, blemishes, and breakouts. When buying an acne treatment people tend to pay attention to the cost, smell, and effect. Differin is fairly cheap for what it can do. I buy my product from Walmart, and it costs me about $11.00, but each bottle can last up to a month. It also has no smell and is very effective for people with oily skin because it has a Benzoyl Peroxide-base, in which it dries out the excessive oil that causes breakouts and blemishes. This product has two counterparts: the Differin Moisturizer and the Differin Gel. The moisturizer is to help moisturize your skin, that way your oil glands don't over excrete to do the same task. This product costs about the same as the cleanser, and it lasts a long time, as I use it twice a day and it has lasted me about four months so far. The gel is an after-treatment that you only use once a day after your face is clean, and it just helps with preventing bad breaks outs. This one can be a little expensive as it is a little bottle and costs about $15.00. Although the Differin cleanser works best with the other two products, it still works great alone. If you use it twice a day, every day, it will do its job in decreasing your acne breakouts and blemishes. Some other reviewers argued that it dries their faces out or it's not effective for sensitive skin. Although everybody's skin is different, and that may have been their skin’s reaction, there are ways around these issues with this product. Since Differin is a cleanser that is meant to dry and decrease the oil from your face, it has the ability to dry your face out completely. To avoid this, be sure to only use it once or twice a day, and I would even recommend investing in the Differin Moisturizer. Overall, Differin Acne Cleanser is a great product for people with acne. It is very cost-effective, has no odor, and even provides loopholes and solutions for those having trouble using this product in the beginning. For me personally, I would recommend Differin Acne Cleanser for an over-the-counter solution, as I have been using it for a year and it has yet to let me down. ... show more
Reviewed in the United States on December 2, 2019 by Sara Hathaway
    • Great for skin care regime!
Size: 4 Fl Oz (Pack of 1)
We combine this cleanser with other Differin products and think very highly of them. They work amazingly for my two teenage boys, both of who send 3-4 hours a day in the summer wearing helmets, as well as one who wrestles. My older son was having trouble with breakouts, and started using this as part of his program and it cleared his face up quickly. This is a great step above basic cleanser before going to a dermatologist or getting on medication. You do want to keep in mind that the first couple weeks, skin will be a bit more dry and more sensitive to the sun, so finding the right balance between using lotion without clogging pores and remembering sunscreen is important! ... show more
Reviewed in the United States on August 19, 2026 by Perry Good Picks
    • The k
Size: 4 Fl Oz (Pack of 1)
This product has been a lifesaver. I was dealing with relentless hormonal adult acne. My skin had zero issues until a few months ago. I was shocked when I started getting jaw breakouts. With the stress of wedding planning, travel, and diet changes—my skin looked almost as bad as it did as a teen. Break out after break out for months. I stopped all the acid based products I was using and gave up on Tretinoin. All I use is this wash, a gentle cleanser and lotion. My skin is doing so much better. This WORKS! ... show more
Reviewed in the United States on July 15, 2026 by Frances E. Ferguson
    • Ok cleanser
Size: 4 Fl Oz (Pack of 1)
Review Image by Thawed
Doesn’t really see result, it will be better it if have more foam but at least doesn’t make me breakout. No smell so it a pro. Won’t make my skins feel tight.
Reviewed in the United States on July 30, 2026 by Thawed
    • On subscription
Size: 4 Fl Oz (Pack of 1)
We have this product on a subscription for AutoShip. Easy to use Great for my own daughter‘s skin. Great for sensitivity.
Reviewed in the United States on August 21, 2026 by Amy

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