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Systane Ultra Lubricant Eye Drops, 60 Count (Pack of 1), (Packaging may vary)

  • Based on 10,157 reviews
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Availability: In Stock.
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Arrives Friday, Apr 24
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Features

  • #1 Dr Recommended Brand of Artificial Tears*
  • Extended Protection
  • Fast Long-Lasting Dry Eye Symptom Relief
  • Reduces both the signs and symptoms of dry eye
  • Single-Use Convenience. Store at room temperature

Description

Systane Ultra Lubricant Eye Drops are clinically proven to deliver extended protection and high-performance relief from your dry eye symptoms. This Ultra formula provides you with the extended relief that you need. These lubricant eye drops have been clinically proven to reduce both the signs and symptoms of dry eye, quickly. Providing immediate, long-lasting moisture and protection Systane Lubricant Eye Drops offer the relief you need to get through your day. You no longer have to suffer through burning and irritation due to your dry eyes, get temporary relief with these lubricant eye drops. Available in multiple size bottles to keep your eyes feeling moist and refreshed during your day. The Systane Family of Products is the 1 Doctor Recommended brand of artificial tears for dry eye symptom relief. Don’t let dry eyes ruin your day, Systane provides temporary relief from your symptoms.

Is Discontinued By Manufacturer ‏ : ‎ No


Product Dimensions ‏ : ‎ 2 x 3.75 x 4.34 inches; 4.69 ounces


Item model number ‏ : ‎ 0065143209


Date First Available ‏ : ‎ September 3, 2015


Manufacturer ‏ : ‎ Alcon Laboratories, Inc


Best Sellers Rank: #1,773 in Health & Household (See Top 100 in Health & Household) #13 in Moisturizing Eye Drops #46 in Vision Products #237 in Sales & Deals


#13 in Moisturizing Eye Drops:


#46 in Vision Products:


#237 in Sales & Deals:


Brand Name: Systane


Product Benefits: Eye Care, Moisturize Skin, Soothing


Specific Uses For Product: Dry Eye


Active Ingredients: Polyethylene Glycol 400 0.4%, Propylene Glycol 0.3%


Item Form: Drop


Age Range Description: All


Target Use Body Part: Eyes


Container Type: Bottle


Flavor: Unflavored


Target Audience: Unisex-Adults


Package Type Name: Box


Model Number: 0065143209


Dosage Form: Drops


Global Trade Identification Number: 53


Manufacturer: Alcon Laboratories, Inc


UPC: 300651432053


Item Weight: 0.29 Pounds


Item Dimensions: 2 x 3.75 x 4.34 inches


Number of Items: 1


Unit Count: 1.2 Fluid Ounces


Net Content Count: 60 Bottle


Additional Features: extended protection


Frequently asked questions

If you place your order now, the estimated arrival date for this product is: Friday, Apr 24

This item is non-returnable:

Non-returnable due to Food safety reasons

View our full returns policy here.

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Top Amazon Reviews


  • Post PRK Eyedrop Review Series
Configuration: Eye Drop
This is a combination review of a handful of preservative free eye drops. This is by no means extensive nor thorough. There are many others on the market that I have yet to try, but these were the ones I believed to be most relevant to my needs, which consist of relief after PRK surgery. Drops reviewed: Refresh Relieva for contacts Systane Gel Drops Systane Hydration PF Biotrue Systane Ultra PF Oasis Tears Plus I will cross post this on each of the other drops' pages. I will review the drops based on relief, perceived longevity, consistency, ease of use, and relevant features. At the time of this review, I am at exactly one month post surgery. I will be rating each of these drops 5 stars on their relevant pages because they all do exactly what they're designed to do and don't have any glaring issues that warrants fewer than 5 stars. The in-post reviews are relevant to comparing between these drops. Refresh Relieva (5 stars): These drops are fantastic. I find that I want to reach for these the most often when I'm looking for good eye lubrication. These drops spread over my eye very quickly without feeling like they stick to the edges of my eyes or eyelashes. Out of all the drops other than the gel, these drops feel like they last the longest in between drops. I use this the least often and find great relief for about half an hour before I want to use them again. These drops feel less slimy than the other drops except for Biotrue. Out of all of the other bottles, it's the most traditional dropper and easiest to use, but due to the design, it may be most susceptible to contaminants and early expiration. It's the only bottle that I'm able to fit my nanodropper onto and that will potentially mitigate the potential contamination and as a result, will prevent early expiration as well as extend the number of drops due to the smaller drops the nanodropper creates. Overall, these are my favorites drops. Systane Gel (3 stars): Out of all of the drops, I reach for these least often. I thought I might try them to see if they last longer and provide the longest lasting relief. If that's what you're looking for, these drops are great, except there are drawbacks that cause me to not use them. They're sticky. If I fall asleep with them in, my eyelids get a little glued together and I sometimes have to pick the gel out of my eyelashes and that can be very uncomfortable. They provide a great deal of relief for the longest period of time and that's the saving grace for these drops, but I'd rather not deal with the slime I get all over my face when I inevitably rub my eyes due to the uncomfortable residue that sits on the edges of my eyes and eyelashes. This dropper is very easy to use and on par with the Refresh dropper. I have no complaints about the amount it drops and the ease of use. Systane Hydration (5 stars): These drops are a very close second to Refresh overall. The relief is only noticeably less than Refresh because the Refresh feels so good. These are exactly what I would expect from a high quality drop and would not be disappointed if these were the only drops available to me. They last about 20-30 minutes and are easy to use. The consistency of these drops is pretty thin. They're only ever so slightly thicker than Biotrue, Ultra, and Refresh. The dropper produces a slight bit of waste if you don't stop squeezing at the right moment but is otherwise very easy to use. Overall, my second favorite drops to use. Biotrue (4 stars): The relief that these drops provide are comparable to Refresh except they don't last as long. I end up having to use these fairly frequently because they don't last very long. I've been using these drops just to get through the bottle. These drops just feel slightly inferior to Systane Hydration in almost every aspect. They go on very nicely and don't stick to my eyelashes or the edges of my eyes as much as Systane, but they don't last as long, provide comparable relief, and the bottle is far more difficult to use. The consistency is the thinnest out of all these drops. This bottle has a special technology that requires a great deal of force to squeeze out a drop. Despite that, the bottle creates a significant amount of waste no matter how you squeeze it, and you have to squeeze it pretty hard. This bottle is my least favorite to use even if the drops are pretty decent. Overall, these are my second to last choice only beating the gels. Systane Ultra PF (5 stars): I think that if I had gotten these in a bottle, they'd be my second favorite to use. They're my go-to for when I'm on the go and need portable drops. They provide a great deal of relief and give about 30 minutes of lubrication. I almost always grab a few of these if I'm going to be out of the house for an extended period of time. The consistency is thin and far less slimy than Hydration. I find that they coat my eye very well and don't stick to my eyelashes and the edges of my eyes. My only issue with these is that they create a significant amount of waste compared to the bottles. I also end up dropping them or losing them when they drop out of my pockets, but they serve a purpose. There's always some product that gets stuck in the twist off cap, so that's a problem too. They're great for transport though, and if I had a bottle, I'd probably prefer it over Hydration. Overall, I really like these drops but I feel bad about the waste. Oasis Tears Plus (3 stars): I feel like these drops are the standard for high quality drops. They provide a fair amount of relief, they last a fair amount of time (roughly 20 minutes), and they're the second most thick drops only less thick than the gel. I don't think I'd get these drops again with these other options. I don't dislike them, but they just don't provide the same amount of relief and longevity as some of the other options. It's also smaller than the Ultra so I get fewer drops out of them. They seem to be smaller so they produce less waste, but not by much. They're very easy to use, but all of these disposable drops produce waste of materials and some product gets stuck in the twist cap, so there's always waste there as well. The Ultra is no different. Overall, I'd probably never use these unless they serve a particular purpose that I'm unaware of. ... show more
Reviewed in the United States on July 7, 2023 by Tam

  • Gentle, Preservative-Free Relief That Really Works.
Configuration: Eye Drop
These Systane Ultra Lubricant Eye Drops have truly made a difference for us. My wife and I have both been using them for a couple of years, and they’ve brought real comfort and relief from dryness and irritation. We love that they’re preservative-free and come in convenient single-use vials — but the best part is that one vial lasts us the entire day and remains just as effective. The drops soothe instantly, keep our eyes hydrated for hours, and are perfect for home or travel. Highly recommended! ... show more
Reviewed in the United States on October 6, 2025 by J.M. Insights

  • awesome product
Configuration: Eye Drop
While the wires are more expensive than a single bottle, the vials are much better. The vials when putting it a drop in your eye it’s more accurate and easier to apply compared to a single bottle . The vile is more sterile. I will stick to the vials over the single bile, even though it might cost more. This product works excellent for dry eye. ... show more
Reviewed in the United States on January 22, 2026 by Prime Member

  • Best eye drops for post LASIK dryness
Configuration: Eye Drop
Ive been using these drops for about 6 months after getting LASIK over a year ago. I have tried many different types of Systane and Refresh eye drops. These by far have been the most refreshing and long lasting ones yet. I use it once in the morning and once before I go to bed. Throughout the day, my eyes no longer feel dry or irritated as how they would using other drops. I usually go through one dropper every 3 days. So this 60 pack lasts me 180 days. These drops are a very good deal and don’t leave any residue on my eyes either. Plus, these are one of the few droppers that I am able to get every speck of liquid out of where as with other style droppers from Systane or refresh, I felt like there was 1 more drop I couldnt get out. ... show more
Reviewed in the United States on February 10, 2026 by Brandon

  • Eye soothing drops
Configuration: Eye Drop
These eye lubricant drops are a great solution for dry, irritated eyes. They provide instant relief, leaving eyes feeling refreshed and comfortable. The formula is smooth and non-irritating, making it easy to apply without any discomfort. They have a long-lasting hydration which helps and has no need for frequent reapplication throughout the day. They deliver soothing moisture to your eyes. ... show more
Reviewed in the United States on May 1, 2025 by Critic

  • Reliable drops that really help
Configuration: Eye Drop
I have been using these for years, and they have always worked well for me. My eye doctor recommends them, and they give quick relief when my eyes feel dry or irritated. The single use vials are easy to carry around and always feel clean and gentle. A dependable product I keep on hand all the time.
Reviewed in the United States on November 22, 2025 by Michael Collins

  • Great soothing eye drops
Configuration: Eye Drop
Great eye drops, always relieves my dry eyes, very soothing.
Reviewed in the United States on January 31, 2026 by BK

  • Very Effective
Configuration: Eye Drop
Very Effective I have been using for dry eyes fo r several weeks with great results. The individual vials are easy to use and contain a VERY generous amount of fluid compared to other products
Reviewed in the United States on March 11, 2026 by Fran Willis

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