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Availability:
In Stock.
Arrives
Tuesday, Nov 17
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At a glance
- Condition
- New
- Size
- 60 Count (Pack of 1)
- Dimensions
- 2 x 3.75 x 4.34 in
- Weight
- 4.64 oz
- Product Benefits
- Eye Care, Moisturize Skin, Soothing
- Item Form
- Drop
- Age Range Description
- All
Features 5
- Fast-Acting Dry Eye Relief for Dry, Irritated Eyes: Systane ULTRA Preservative-Free Lubricant Eye Drops provide rapid hydration and lasting relief for dry eyes caused by irritants like screen time, air quality, low humidity, or seasonal changes. Designed for occasional or mild dry eye sufferers
- Targets the Aqueous Layer: Formulated with Polyethylene Glycol 400 and Propylene Glycol, our moisturizing eye drops for dry eyes help hydrate and protect the ocular surface by replenishing the aqueous (water) layer of the tear film to deliver fast-acting and long-lasting dry eye relief throughout the day
- Gentle Preservative-Free Formula: Suitable for sensitive eyes, the preservative-free formula of Systane ULTRA Preservative-Free Lubricating Eye Drops helps soothe eye dryness without preservatives. Helps relieve discomfort to the eye caused by wind, dust, or extended screen exposure, making it suitable for everyday use
- Convenient & Hygienic Application: Available in an easy-to-use unit-dose vials providing a sterile, travel-friendly option. A great addition to your daily eye care routine, instill 12 drops as needed throughout the day. These lubricating eye drops help restore comfort, whether you're at your desk or on the go
- Trusted Brand, Convenient Design: Systane is a trusted name in eye care, recommended by eye care professionals for reliable dry eye relief. The single-use vials offer on-the-go hydration, keeping eyes refreshed and moisturized wherever your day takes you
Description
Systane ULTRA Preservative Free Lubricant Eye Drops, for Fast-Acting Dry Eye ReliefGet fast-acting dry eye relief from dry, irritated eyes with Systane ULTRA Preservative-free Lubricating Eye Drops, designed to hydrate, soothe, and refresh your eyes whenever you need it most. Known for providing extended protection and high-performance symptom relief, this advanced formula eye drop helps combat dryness caused by environmental factors, including screen time, air quality, seasonal changes, low humidity, high winds, and dust.Systane ULTRA Preservative-free targets the aqueous layer, helping to deliver quick hydration to the ocular surface for long-lasting comfort. It helps relieve burning, irritation, and dryness caused by everyday exposure to wind or sun, keeping your eyes feeling moisturized and refreshed. Place 1 or 2 drops in the affected eye(s) as needed and blink.Available as single-use vials, Systane ULTRA Preservative Free Eye Drops are designed for individuals with occasional or mild dry eye symptoms seeking a reliable solution. Safe for use with soft contact lenses (not a rewetting drop). It can be applied as needed throughout the day to keep your eyes feeling hydrated and protected. Systane is a trusted name in eye care, recommended by eye care professionals for reliable dry eye relief.
Specs 25
| Product Dimensions | 2 x 3.75 x 4.34 inches; 4.69 ounces |
|---|---|
| Item model number | 0065143209 |
| Manufacturer | Alcon Laboratories, Inc |
| Brand Name | Systane |
| Product Benefits | Eye Care, Moisturize Skin, Soothing |
| Specific Uses For Product | Dry Eye |
| Active Ingredients | Polyethylene Glycol 400 0.4%, Propylene Glycol 0.3% |
| Item Form | Drop |
| Age Range Description | All |
| Target Use Body Part | Eyes |
| Container Type | Bottle |
| Flavor | Unflavored |
| Target Audience | Unisex-Adults |
| Package Type Name | Box |
| Model Number | 0065143209 |
| Dosage Form | Drops |
| Global Trade Identification Number | 53 |
| Item Highlight | Single-Use Vials, Fast-Acting Relief from Irritation & Dryness, Hydrating Eye Drops for Extended Protection |
| UPC | 300651432053 |
| Item Weight | 4.64 ounces |
| Item Dimensions | 2 x 3.75 x 4.34 inches |
| Number of Items | 1 |
| Unit Count | 1.2 Fluid Ounces |
| Net Content Count | 60 bottle |
| Additional Features | Long-Lasting |
No specs match.
Frequently asked questions
If you place your order now, the estimated arrival date for this product is:
Tuesday, Nov 17
This item is non-returnable:
Non-returnable due to Food safety reasons
View our full returns policy here.
Non-returnable due to Food safety reasons
View our full returns policy here.
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Top Amazon Reviews
The BEST For My Dry Eyes
Size: 60 Count (Pack of 1)
I know these vials are expensive for daily use — and I originally got them for travel only — but I like them so much that I use them everyday. Systane’s PF drops in a container are a pain to use, especially since the instructions have you going through a ritual to ensure that the fluid doesn’t stay in the top. I much prefer paying extra to get my daily dosage in a vial. If I use them in the morning, they are good for at least 8 hours and sometimes more. Because I wear contacts, I have to administer these at least 30 minutes before I put in my lenses and then only after I remove them at the end of the day. Mostly, I don’t use these drops at the end of the day, though. That way, 30 vials last a whole month, with these 60 vials (obviously) lasting about two months, minus a day or two. These are perfect for travel since they are pre-measured for one-time use. One vial contains more than enough to use two drops in each eye. You can’t save the remainder even if you don’t use it all — they must be discarded for safety.
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Reviewed in the United States on May 16, 2026 by Debbie Lee Wesselmann
One of the Few Eye Drops Both My Ophthalmologist and Optometrist Consistently Recommend
Size: 60 Count (Pack of 1)
These were originally recommended to me by both my ophthalmologist and optometrist, especially for ongoing dryness and irritation, and they have honestly been one of the more reliable eye care products I’ve used. The preservative-free formula makes a noticeable difference for sensitive eyes or frequent daily use because the drops feel soothing without creating additional irritation over time the way some standard eye drops can. Relief is almost immediate, and they leave the eyes feeling comfortably hydrated rather than temporarily coated or blurry. I also really appreciate the individual vials. They stay clean, are easy to keep in a purse, vehicle, travel bag, desk, or nightstand, and make it much easier to use the drops throughout the day without worrying about contamination. The box arrived sealed properly, packaged well, and all of the vials were intact during shipping. While they are more expensive than some generic eye drops, the quality and comfort level absolutely feel worth it if you struggle with chronic dryness or sensitive eyes. Sometimes the products eye professionals repeatedly recommend truly are the ones that work best, and this has definitely been one of those for me. #AmazonFinds #Systane #DryEyeRelief #EyeCare #PreservativeFree #WellnessLifestyle #OphthalmologistRecommended #OptometristRecommended #DailyEssentials #SelfCare #HealthSupport #LuxeLife
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Reviewed in the United States on May 8, 2026 by VanillaPepper
Great product! & Great deal!
Size: 60 Count (Pack of 1)
I have dry eye disease (DED), Systane UlTRA PF is a great hydration without eye irritation or burning. It instantly soothes your eyes. Unscented. The single use vials are very convenient to carry with you wherever you go. Made for one time use but I most of the time get at least two. I haven’t found them any cheaper than on Amazon. So great deal!
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Reviewed in the United States on June 15, 2026 by Fatina Williard
Post PRK Eyedrop Review Series
Size: 60 Count (Pack of 1)
This is a combination review of a handful of preservative free eye drops. This is by no means extensive nor thorough. There are many others on the market that I have yet to try, but these were the ones I believed to be most relevant to my needs, which consist of relief after PRK surgery. Drops reviewed: Refresh Relieva for contacts Systane Gel Drops Systane Hydration PF Biotrue Systane Ultra PF Oasis Tears Plus I will cross post this on each of the other drops' pages. I will review the drops based on relief, perceived longevity, consistency, ease of use, and relevant features. At the time of this review, I am at exactly one month post surgery. I will be rating each of these drops 5 stars on their relevant pages because they all do exactly what they're designed to do and don't have any glaring issues that warrants fewer than 5 stars. The in-post reviews are relevant to comparing between these drops. Refresh Relieva (5 stars): These drops are fantastic. I find that I want to reach for these the most often when I'm looking for good eye lubrication. These drops spread over my eye very quickly without feeling like they stick to the edges of my eyes or eyelashes. Out of all the drops other than the gel, these drops feel like they last the longest in between drops. I use this the least often and find great relief for about half an hour before I want to use them again. These drops feel less slimy than the other drops except for Biotrue. Out of all of the other bottles, it's the most traditional dropper and easiest to use, but due to the design, it may be most susceptible to contaminants and early expiration. It's the only bottle that I'm able to fit my nanodropper onto and that will potentially mitigate the potential contamination and as a result, will prevent early expiration as well as extend the number of drops due to the smaller drops the nanodropper creates. Overall, these are my favorites drops. Systane Gel (3 stars): Out of all of the drops, I reach for these least often. I thought I might try them to see if they last longer and provide the longest lasting relief. If that's what you're looking for, these drops are great, except there are drawbacks that cause me to not use them. They're sticky. If I fall asleep with them in, my eyelids get a little glued together and I sometimes have to pick the gel out of my eyelashes and that can be very uncomfortable. They provide a great deal of relief for the longest period of time and that's the saving grace for these drops, but I'd rather not deal with the slime I get all over my face when I inevitably rub my eyes due to the uncomfortable residue that sits on the edges of my eyes and eyelashes. This dropper is very easy to use and on par with the Refresh dropper. I have no complaints about the amount it drops and the ease of use. Systane Hydration (5 stars): These drops are a very close second to Refresh overall. The relief is only noticeably less than Refresh because the Refresh feels so good. These are exactly what I would expect from a high quality drop and would not be disappointed if these were the only drops available to me. They last about 20-30 minutes and are easy to use. The consistency of these drops is pretty thin. They're only ever so slightly thicker than Biotrue, Ultra, and Refresh. The dropper produces a slight bit of waste if you don't stop squeezing at the right moment but is otherwise very easy to use. Overall, my second favorite drops to use. Biotrue (4 stars): The relief that these drops provide are comparable to Refresh except they don't last as long. I end up having to use these fairly frequently because they don't last very long. I've been using these drops just to get through the bottle. These drops just feel slightly inferior to Systane Hydration in almost every aspect. They go on very nicely and don't stick to my eyelashes or the edges of my eyes as much as Systane, but they don't last as long, provide comparable relief, and the bottle is far more difficult to use. The consistency is the thinnest out of all these drops. This bottle has a special technology that requires a great deal of force to squeeze out a drop. Despite that, the bottle creates a significant amount of waste no matter how you squeeze it, and you have to squeeze it pretty hard. This bottle is my least favorite to use even if the drops are pretty decent. Overall, these are my second to last choice only beating the gels. Systane Ultra PF (5 stars): I think that if I had gotten these in a bottle, they'd be my second favorite to use. They're my go-to for when I'm on the go and need portable drops. They provide a great deal of relief and give about 30 minutes of lubrication. I almost always grab a few of these if I'm going to be out of the house for an extended period of time. The consistency is thin and far less slimy than Hydration. I find that they coat my eye very well and don't stick to my eyelashes and the edges of my eyes. My only issue with these is that they create a significant amount of waste compared to the bottles. I also end up dropping them or losing them when they drop out of my pockets, but they serve a purpose. There's always some product that gets stuck in the twist off cap, so that's a problem too. They're great for transport though, and if I had a bottle, I'd probably prefer it over Hydration. Overall, I really like these drops but I feel bad about the waste. Oasis Tears Plus (3 stars): I feel like these drops are the standard for high quality drops. They provide a fair amount of relief, they last a fair amount of time (roughly 20 minutes), and they're the second most thick drops only less thick than the gel. I don't think I'd get these drops again with these other options. I don't dislike them, but they just don't provide the same amount of relief and longevity as some of the other options. It's also smaller than the Ultra so I get fewer drops out of them. They seem to be smaller so they produce less waste, but not by much. They're very easy to use, but all of these disposable drops produce waste of materials and some product gets stuck in the twist cap, so there's always waste there as well. The Ultra is no different. Overall, I'd probably never use these unless they serve a particular purpose that I'm unaware of.
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Reviewed in the United States on July 7, 2023 by Tam
Great Dry Eye Product
Size: 60 Count (Pack of 1)
These are the best eye drops that are over the counter, that I have used for dry eyes. The Ultra Preservative free work even better than the Systane Preservative free. I haven't had a problem with the Ultra PF, when I did have an issue with the just Preservative Free. If you have a dry eye problem, I highly recommend.
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Reviewed in the United States on August 31, 2026 by Sandra De
Love the Product, hate the Packaging
Size: 60 Count (Pack of 1)
These eye drops work wonderfully well, but the packaging is so horrible and hard to open. They are for traveling, but we do not travel much anymore. How come I order a bottle, and get this type of packaging? These single use (?) units are very hard to use.
Reviewed in the United States on December 5, 2025 by Charlene Lee
Dry eye drops better than a tissue !!!😜
Size: 60 Count (Pack of 1)
Preservative free is the best and Eye Dr. recommends it ! Easy to apply plus the vial can be used twice w the twist off and replaceable tab cap !! Soothing!
Reviewed in the United States on July 12, 2026 by linda malley
Nice and soothing drops
Size: 60 Count (Pack of 1)
Nice and soothing eye drops especially for dry eyes.
Reviewed in the United States on August 12, 2026 by KareeGirl