Seachem 437 Prime Fresh and Saltwater Conditioner - Chemical Remover and Detoxifier 1L
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Availability:
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Tuesday, Jul 21
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Size: 1000 mL
Style: Conditioner
Features
- POWERFUL TREATMENT: Seachem Prime is a complete and concentrated conditioner for both freshwater and saltwater fish tanks, working hard to remove chlorine and chloramine.
- REMOVER: Seachem Prime immediately and permanently removes chlorine and chloramine, successfully allowing the bio filter to remove ammonia, nitrite, and nitrate while they are detoxified for 48 hours.
- DETOXIFIER: Seachem Prime effectively detoxifies ammonia, nitrite, and heavy metals found in the tap water at typical concentration levels, providing a safe environment for your betta, tetra, or other fish.
- USE: Use 1 capful (5 mL) of Seachem Prime for each 200 L (50 US gallons) of new or replacement water. For best results, add Seachem Prime to new water first. For exceptionally high chloramine concentrations, a double dose may be used safely. For smaller volumes, use 2 drops per gallon.
- SAFETY: In case of an emergency, the 5x dose of Seachem Prime may be used for both ammonia and nitrite. Use a 12 dose if the water temperature is > 30C (86F) and chlorine or ammonia levels are low.
Description
Seachem 437 Prime Fresh and Saltwater Conditioner - Chemical Remover and Detoxifier 1L
Brand: Seachem
Liquid Volume: 1 Liters
Item Weight: 33.8 Ounces
Item Form: Liquid
Number of Packs: 1
Is Discontinued By Manufacturer : No
Product Dimensions : 3.2 x 3.2 x 9 inches; 2.11 Pounds
Item model number : 437
Department : Unisex-Adult
Date First Available : December 1, 2016
Manufacturer : Seachem Laboratories, Inc.
Best Sellers Rank: #410 in Pet Supplies (See Top 100 in Pet Supplies) #1 in Aquarium Water Treatments
#1 in Aquarium Water Treatments:
Customer Reviews: 4.8 4.8 out of 5 stars (43,073)
Brand Name: Seachem
Manufacturer: Seachem Laboratories, Inc.
UPC: 000116043700
Global Trade Identification Number: 00
Model Number: 437
Manufacturer Part Number: FBA_437
Unit Count: 1 Count
Warranty Description: Warranty
Item Type Name: Seachem 437 Prime Fresh and Saltwater Conditioner - Chemical Remover and Detoxifier 1L
Included Components: Seachem 437 Prime Fresh and Saltwater Conditioner - Chemical Remover and Detoxifier 1L
Liquid Volume: 1 Liters
Item Weight: 33.8 Ounces
Item Form: Liquid
Pet Type: Fish
Target Species: Fish
Allergen Information: Yam Free
Frequently asked questions
If you place your order now, the estimated arrival date for this product is:
Tuesday, Jul 21
Yes, absolutely! You may return this product for a full refund within 30 days of receiving it.
To initiate a return, please visit our Returns Center.
View our full returns policy here.
To initiate a return, please visit our Returns Center.
View our full returns policy here.
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Top Amazon Reviews
Size: 1000 mL
Style: Conditioner
As someone who's been deeply involved in the aquarium hobby for over two decades, I can confidently say that Seachem Prime is, without a doubt, the single most essential product in my fish room. I was introduced to Prime when I first started out, and it quickly became the cornerstone of my water care routine. Twenty-plus years later, it remains the only water conditioner I trust and use in all my tanks. Prime does exactly what it promises, and it does it exceptionally well. It instantly neutralizes chlorine, chloramine, and ammonia, making tap water safe for your aquatic inhabitants. Beyond that, it detoxifies nitrite and nitrate, which is a huge bonus, especially during cycling or in emergency situations. The fact that it does all of this in a concentrated formula means a little goes a very long way, making the 1L bottle incredibly economical and long-lasting. What truly sets Prime apart, for me, is its reliability and the peace of mind it provides. I've never had a single issue with water parameters or fish health that could be attributed to Prime. It's truly a "set it and forget it" product that allows me to focus on the joy of the hobby rather than worrying about water quality. If you're new to the hobby, do yourself a favor and start with Prime. If you're a seasoned aquarist looking for the best, you already know what I'm talking about. I exclusively use Seachem products in my tanks because their quality and effectiveness are unmatched, and Prime is the shining star of their lineup. This isn't just a water conditioner; it's an investment in the health and longevity of your aquatic ecosystem. Five stars, hands down!
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Reviewed in the United States on May 29, 2025 by Alicia
Size: 500 mL
Style: Conditioner
From Cichlids to Fancy Goldfish I've been keeping fish for 30+ years.Just about every major manufacture and boutique specialty company has a water conditioning and treatment product.I can't say I've tried them all, but close too it. Some products have at the least, minimal effectiveness while others can be potentially dangerous. An example would be Stress Coat which has binding sugar strands in the Aloe. This isn't a problem unless one of your fish has a small scratch or wound.The sugar feeds the bacteria which can lead to major infection and dire consequences.I've been using Amquel for years and it's a fine conditioner, excellent at removing chlorine, and Chloramines, but like all these products - they come with limitations. Well, with one exception and that's Prime by Seachem. A few months ago, I decided to give it a try, and haven't looked back since. Prime doesn't just remove the chlorine and Chloramine it does much more: * Detoxifies any and all heavy metals in your tap water (you can call your water company directly for a list of them and PPM) * Neutralizes Ammonia * Neutralizes Nitrite * Neutralizes high Nitrate to non toxic levels * Removes toxic gases * Will not foam or change PH * Helps regenerate natural slime coat Since using Prime, I've seen a dramatic improvement in all of my fish. In 2010 one of tanks was hit with the dreaded and rare Toxic Tank Syndrome - within 48 hours I had lost nine gorgeous fish - except for one survivor, a single Broad Tail Nymph.Since that ordeal, "Roxy" became a bottom dweller spending most of her time laying in a corner. Treatments were conservative, but nothing worked. After my first 50% water change using Prime her behavior began to improve. Now she swims among her tank mates, her color is better, gill movement stabilized and her appetite ferocious. In fact I see improvements in all my fish and in every tank.There simply isn't anything like it, Prime is hands down one of the best things you can do for your fish. In addition to the outstanding, patented formula of Prime - it couldn't be more economical to use. A single 500 ml bottle treats up to a whopping 5,000 gallons of water. A tiny bit goes a long, long way.It should also be noted that in times of emergency the dose can be increased five times, Prime is harmless to fish.It's the only product of it's kind, and towers above any other water treatment on the market - period. If your an aquarium hobbyist be it novice or advanced - I would urge you to add a bottle of Prime to your arsenal of fish care products. Your finned friends will thank you for it.
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Reviewed in the United States on April 6, 2025 by James Williams
Size: 250 mL
Style: Conditioner
We used this conditioner when setting up our tank and it made the whole process much less stressful. It was reassuring knowing the water was treated properly before introducing any fish, and the tank looked clear and stable very quickly. After using it, everything tested where it should be, and when we finally added our fish they adjusted without any issues, which told us it was doing its job. I really like that a little goes a long way, so the bottle should last quite a while even with regular water changes. It gave us peace of mind during setup and made us feel confident that we weren’t putting our fish into unsafe water. The only downside is that the dosing is very concentrated, so you have to measure carefully especially with smaller tanks to avoid adding too much. Overall, this is a solid conditioner that worked exactly as advertised and helped get our tank ready the right way before adding fish.
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Reviewed in the United States on December 30, 2025 Reviewed in the United States on December 30, 2025 by One-Click Picks
Size: 500 mL
Style: Conditioner
Doing an emergency fish in cycle for my tank and this stuff is amazing. Can get me through the trials of being a new fish owner and keep him safe till healthy bacteria is established in my tank. Performing Emergency fish-in cycle with Seachem Prime Step 1: Set up your aquarium It’s time to set up your aquarium. And, that includes all the equipment – heaters, filters, air pumps… Get it in there! Don’t forget to rinse it with fresh water first! The beneficial bacteria need a surface to cling to, namely your substrate and filter media. So by setting everything up, you give your bacteria as many surfaces as possible to cling to. Add water to the tank, and don’t forget to dechlorinate it with your water conditioner first. Finally, you want to keep all electrical equipment, such as heaters, filters and bubblers, switched on throughout the entire cycling process. Not only will this keep your fish as comfortable as possible, but it will also make your tank cycle faster. Want to cycle your tank as quickly as possible? Check out FishLab’s tips for speeding up the cycling process. Step 2: Adding your fish Before you add your fish, you want to acclimate them first. This will give them the best chance of survival. You want to feed your fish throughout the cycling process… You don’t want them to starve! When feeding your fish, however, it’s important that you don’t feed them too much. The more you feed them, the more they are going to poop. And the more they poop, the faster your ammonia levels are going to rise. Also, remove any uneaten food from the tank, a good aquarium net will make this easy. Any uneaten food left behind will break down into ammonia, causing the levels to rise. If a fish dies during the cycle, remove it from the aquarium ASAP. Its decaying body will also give off ammonia. Don’t panic if one of your fish dies. It doesn’t necessarily mean that all your fish will – this one might have been extra sensitive. Step 3: Test, test, test, and test again Now, use your ammonia test kit every 24 hours. What you are looking for is any sign of ammonia. Trust me. It won’t be long before it appears. Once your test kit returns positive for ammonia, it’s time to move to the next step. Step 4: Dealing with ammonia Once you detect ammonia, it’s time to start dosing with Seachem Prime. Follow the instructions on the bottle to determine what a single dose would be for your tank – the larger the aquarium, the more Prime you will need. Fortunately, a little goes a long way, and many of you will find that a single bottle of Prime will get you through an entire cycle. For this method, Seachem Prime is the most important ingredient. You see, a dose of Prime will bind ammonia, nitrite and nitrate for 24 to 48 hours, making them harmless to your fish. Picture Seachem Prime locking up ammonia, nitrite and nitrate in a jail cell for up to 48 hours. While in the cell, these nasties cannot harm your fish. However, once their time is up, and they are released, they will once again attack your fish. It is for this reason that you need to dose regularly with Seachem Prime, to keep these nasties locked up. A single dose of Prime will treat up to 1 part per million (ppm) of ammonia. Prime can be dosed up to 5 times safely. So, 2 ppm of ammonia can be treated with two doses of Prime, 3 ppm can be treated with three doses, and so on. Anything less than 1 ppm should be treated with a single dose. Between 1 ppm and 2 ppm, two doses. You get the idea. Oh, and it goes without saying that it’s better to overdose than underdose. *Once your test kit reads 2 ppm of ammonia, you should perform a 50% water change. This should cut your ammonia levels roughly in half. Repeat this process until you notice that your ammonia levels are not rising as quickly as before. Typically, this will take a week or two. When this happens, you are ready to move to the next step. Bookmark this page so that you can easily find it when you are ready for the next step! Step 5: Nitrites start to appear Next, you need to test for nitrites. If none are present, keep repeating the previous step and testing for nitrites daily until you get a positive result. Now that nitrite has entered the equation, you need to make sure you are dosing with enough Prime to protect your fish from both ammonia and nitrites. Fortunately, working out your new dosage is pretty simple – just add your nitrite and ammonia readings together. Let’s say your test returns the following… Ammonia 0.25 ppm Nitrite 1.5 ppm Adding the two together will give you a total of 1.75 ppm. A double dose of Prime will take care of it. This time, if your combined ppm of ammonia and nitrite reaches 4, perform a 50% water change. Keep repeating this. You will eventually notice that your ammonia drops to zero. This is a good thing – bacteria are eating the ammonia as quickly as it is being produced, resulting in a zero reading. Continue daily dosing and testing for ammonia and nitrites. Once your nitrite levels stop rising as quickly, you are ready for the next step. Step 6: Nitrates appear Now, you want to test for nitrates. If none are present, keep repeating the previous step and testing for nitrates daily until you get a positive result. Once nitrates are present, you are nearing the end (woohoo!). Continue testing for ammonia, nitrites and nitrates. Your ammonia levels should still be zero, and your nitrite levels should be declining. Keep dosing with Prime until both your nitrite and ammonia levels are zero. At this stage, the beneficial bacteria are eating them as quickly as they are being produced. Congratulations! You have successfully completed a fish-in cycle.
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Reviewed in the United States on May 2, 2021 Reviewed in the United States on May 2, 2021 by Cory
Size: 250 mL
Style: Conditioner
I use this product to remove chlorine from my tap water to water my houseplants with. Keeps spider plants from getting brown tips. Lasts forever, this is the second bottle I've purchased over the years. A wonderful product. Is a little stinky before you add the water. Like a sulphur smell.
Reviewed in the United States on June 7, 2026 by Anon
Size: 250 mL
Style: Conditioner
Stinks but it works well, has two gold fish in a 40 and less then a capful was clear in hours, does have very strong sulfur smell so if sensitive to that smell then I’d avoid this stuff.. otherwise works as advertised.
Reviewed in the United States on May 25, 2026 by xXIDadIXx
Size: 500 mL
Style: Conditioner
Seachem Prime does a solid job at making tap water safe for both freshwater and saltwater tanks. It removes chlorine and chloramine and helps detoxify ammonia and nitrite, which gives some peace of mind during water changes. A little goes a long way since it’s very concentrated, so one bottle lasts quite a while. The only downside for me is the smell—it has a strong sulfur-like odor that can be unpleasant. Also, if you use too much, it might make the water a bit cloudy or cause your skimmer to react in saltwater setups. Overall, it’s a reliable and effective conditioner that most aquarists will find useful, even if it’s not the nicest-smelling product out there.
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Reviewed in the United States on November 10, 2025 by JOJO
Size: 250 mL
Style: Conditioner
this is the best product out there for dechlorination of water. it keeps my water stable! I highly recommend it
Reviewed in the United States on June 19, 2026 by Teri Vera Schneider von Marbod