Search  for anything...

Seachem Prime Fresh and Saltwater Conditioner - Chemical Remover and Detoxifier 16.9 fl. oz

  • Based on 2,234 reviews
Condition: One-time purchase
Checking for the best price...
$18.48 Why this price?
Holiday Deal · 6% off was $19.69

Buy Now, Pay Later


As low as $4 / mo
  • – 4-month term
  • – No impact on credit
  • – Instant approval decision
  • – Secure and straightforward checkout

Ready to go? Add this product to your cart and select a plan during checkout.

Payment plans are offered through our trusted finance partners Klarna, Affirm, Afterpay, Apple Pay, and PayTomorrow. No-credit-needed leasing options through Acima may also be available at checkout.

Learn more about financing & leasing here.

Free shipping on this product

Non-returnable due to Food safety reasons

View our full returns policy here.


Availability: In Stock.
Fulfilled by Amazon

Arrives Saturday, Nov 15
Order within 20 hours and 55 minutes
Available payment plans shown during checkout

Description

Complete and concentrated conditioner for both fresh and saltwater. Seachem 437 Prime Fresh and Saltwater Conditioner - Chemical Remover and Detoxifier 500ml

Brand: Seachem


Liquid Volume: 500 Milliliters


Item Weight: 0.61 Kilograms


Item Form: Liquid


Manufacturer: Seachem


Is Discontinued By Manufacturer ‏ : ‎ No


Product Dimensions ‏ : ‎ 6.6 x 2.3 x 2.5 inches; 1.34 Pounds


Item model number ‏ : ‎ SE0433


UPC ‏ :


Manufacturer ‏ : ‎ Seachem


Units ‏ : ‎ 16.9 Fluid Ounces


Best Sellers Rank: #11,625 in Pet Supplies (See Top 100 in Pet Supplies) #79 in Aquarium Water Treatments


#79 in Aquarium Water Treatments:


Customer Reviews: 4.9 4.9 out of 5 stars 2,234 ratings


Frequently asked questions

If you place your order now, the estimated arrival date for this product is: Saturday, Nov 15

This item is non-returnable:

Non-returnable due to Food safety reasons

View our full returns policy here.

  • Klarna Financing
  • Affirm Pay in 4
  • Affirm Financing
  • Afterpay Financing
  • PayTomorrow Financing
  • Financing through Apple Pay
Leasing options through Acima may also be available during checkout.

Learn more about financing & leasing here.

Top Amazon Reviews


  • Love this stuff!!
This is the best water conditioner on the market! It also lasts forever if you only have a 30 gallon tank like I do. I throw it in there if my ammonia is too high and then do a water change the following day.
Reviewed in the United States on September 28, 2025 by Steph

  • The best antichlor product.
Ive used several brands of aquarium chemicals and conditioners. Prime is the best Ive found that removes chlorine, chloromine, ammonia and some heavy metals. Its fantastic at doing this. Following the listed dosing instructions seldom leads to any issues. But, the dosing instructions are only estimates as every municipal water system has differing amounts of hazardous chemicals and can even vary hour to hour. You can safely overdose the suggested amount to treat heavily doped city water. Bit if you do overdose too much, and far exceed the amount of chemicals in the water, Prime will tend to go after oxygen in the water too. If you notice the fish at the top gasping for air after adding a large dose of Prime, youve likely overdosed Prime. You can solve this overdose within often minutes by having an air stone bubbling heavily in the tank water. This will usually get enough water and air circulated to get oxygen back into the water within minutes. Frankly most tanks can benefit from an air stone all the time anyway. But if you follow dosing instructions, youll find you can use less Prime than the other brands and save some money while protecting your fish from municipal chemicals. Prime doesnt add slimecoat to the water. So sensitive fish like Cories and Loaches are better served. You can also use Prime to clean filter media recycled with Ammonia. High doses of Prime removes the ammonia solution used to clean. It can be added at each water change or small doses can help alleviate ammonia or nitrite spikes temporarily. It can be purchased in small little 250ml bottles clear up to 2l bottles for ponds or if you use it to detoxiify ammonia soaked Purigen. It does have an expiration date but will isually at last a year or so after bottled. Just be sure its shaken and mixed before applying. Also both in the bottle and when nuetralizing chemicals, it gives off a strong sulphur odor that disipates quickly. Sniffing the bottle could make you sick. You can store it at room temperature but dont let it set out in sunlight or to freeze. This is the most important and reliable chemical treatment I use. And I use it often in my tanks, especialy during water changing days. I usually get 1L or 500ml at a time. If youve only got one small tank, the 250ml size might be better for you. I always keep it on hand. ... show more
Reviewed in the United States on September 21, 2024 by Don Gray

  • Good for pet axolotls.
This stuff is always great. I use it for my pet axolotl, and it's the exact product I would recommend for them specifically. It also works great for fish and other amphibians. It is VERY concentrated so a little goes a long way.
Reviewed in the United States on September 2, 2025 by Amanda Butler

  • Amazing chemicals from prime
Prime makes amazing pond chemicals , they are my go to brand to keep my pond water in a good state. They are very potent so the dose is small and it’s a good bang for your buck they last so long!
Reviewed in the United States on May 6, 2025 by Teresa Lima

  • A must have!
An essential for all aquarium owners!
Reviewed in the United States on August 8, 2025 by Allie

  • Good!
So far so good!! Stinks to high heavens but that’s normal apparently. No issues so far and good size! I could see this lasting a long time for my 20 gallon tank.
Reviewed in the United States on May 19, 2025 by Gracie Newsome

  • If you need a dechlorinator, this is the one you want
I like fish tanks and keeping fish alive and happy. Do you? Then you should use Prime. I haven't compared prices in a while to other dechlorinators, but even if they are a lot cheaper I'd still use Prime. I do a 10% water change every day (yes, every day... I know I know, that seems excessive... but I like doing it, that's why I have a fish tank because I like taking care of them... besides, it's only 20 gallons so it takes me like eight minutes since I'm only changing 2 gallons and it seems to stress my fish out less and make them happy more than more infrequent but larger water changes) on my 20 gallon tank and a 500mL bottle lasts me about 9 months to a year. You don't need much per gallon. In fact, I've taken to putting a small hole at opposite ends of the aluminum covering when you first get it so I can limit how much I'm putting in because when dealing with small water changes it is actually kinda hard to not put way too much in (not that it would be a problem if I did, since Prime does not immediately harm fish if you overdose, which is also nice and a selling point). In conclusion: If you need dechlorinator, get Prime. ... show more
Reviewed in the United States on July 20, 2023 by bakerwulf

  • Gotta love it!
Super reliable product. I've been using this for years.
Reviewed in the United States on June 12, 2025 by Emanon

Can't find a product?

Find it on Amazon first, then paste the link below.
Checking for best price...