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Sunergetic

4-in-1 Probiotic Prebiotic & Postbiotic with Digestive Enzymes, 60 Capsules

  • Based on 1,132 reviews
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Availability: In Stock.
Fulfilled by Amazon
Arrives Tuesday, Oct 27
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Features

  • Four Parts, One Routine: Probiotics, prebiotics, postbiotics, and digestive enzymes come together in a convenient 2-capsule serving
  • DE111 & PreforPro: Features DE111 within a multi-strain probiotic blend, paired with PreforPro prebiotic and a postbiotic dried yeast fermentate
  • Gut, Digestion & Immune Health: Supports healthy digestion, gut health, regularity, and immune health as part of a consistent routine
  • Simple Daily Format: Pre-measured capsules bring the full 4-in-1 formula together with no mixing, measuring, or refrigeration required
  • 60 Capsules, 30 Servings: Adults take 2 capsules daily, preferably with a meal, or as directed by a healthcare professional; review the label for allergen information

Package Dimensions ‏ : ‎ 4.02 x 1.81 x 1.81 inches; 1.76 ounces


Date First Available ‏ : ‎ November 11, 2024


Manufacturer ‏ : ‎ Sunergetic


Best Sellers Rank: #10,164 in Health & Household (See Top 100 in Health & Household) #34 in Multi-Enzyme Nutritional Supplements


#34 in Multi-Enzyme Nutritional Supplements:


Customer Reviews: 4.4 4.4 out of 5 stars (1,132)


Brand Name: Sunergetic


Primary Supplement Type: Digestive Enzyme Blend, Dried Yeast Fermentate, PreforPro®, Probiotic Blend


Item Form: Capsule


Product Benefits: 4-in-1 probiotic supplement, Gut Health Support, Immune Support, bio complete 3


Age Range Description: Adult


Container Type: Bottle


Dosage Form: Capsule


Supplement Formulation: Multi-Supplement


UPC: 852207008729


Item Highlight: Daily tribiotic for men & women with DE111, PreforPro, dried yeast fermentate & enzymes; 30 servings, no refrigeration


Manufacturer: Sunergetic


Manufacturer Part Number: PROB-4IN1-60


Unit Count: 60 Count


Number of Items: 1


Total Servings Per Container: 30


Flavor: Unflavored


Special Ingredients: Prebiotic, Probiotic


Material Features: GMO Free, Made in USA with globally sourced ingredients, Made without synthetic ingredients


Specific Uses For Product: 4-in-1 Prebiotic Probiotic & Postbiotic for Women & Men Complete Gut & Digestive Support Supplement Colon Health Daily Probiotic Capsules 4-in-1 Symptom Defense to help defend against Occasional Gas, Bloating, Constipation, and Diarrhea 4-in-1 Probiotics for Women Daily Probiotic & Prebiotic Supplement pre pro post with digestive enzymes


Allergen Information: Milk, Soy, Wheat


Frequently asked questions

If you place your order now, the estimated arrival date for this product is: Tuesday, Oct 27

This item is non-returnable:

Non-returnable due to Food safety reasons

View our full returns policy here.

  • Klarna Financing
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  • Financing through Google Pay
Leasing options through Acima may also be available during checkout.

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Top Amazon Reviews

    • Good
Good product that helps with regularity and prevents bloating.
Reviewed in the United States on November 30, 2025 by jillian
    • Much better than any others I’ve tried
I’ve been on probiotics for a while and it improved my gut health a lot. A friend recommended this as a less expensive alternative to Bioma. She really like these. So I switched I noticed a better result and am feeling great. After 3 weeks it is now on subscribe and save. Never going back
Reviewed in the United States on October 27, 2025 by Theana L Theobald
    • Five star product⭐️⭐️⭐️⭐️⭐️
Very great product not works well on gut health, very easy to swallow, very great on digestion in the afternoon and next morning, and it works well on weight lost because of the new found energy I have to do more and be more better on my consistency.
Reviewed in the United States on October 19, 2025 by Lou
    • Probiotics
Worked well to correct digestion issues.
Reviewed in the United States on December 11, 2025 by BRETA DESBONNE
    • Great product and affordable!
This is my third bottle, and I noticed a difference since I haven't had it in about two weeks. There was a clear difference from when I started using it and I wanted to see how it was being without it for two weeks or so and I can definitely tell the difference in my midsection.
Reviewed in the United States on October 10, 2025 by Vince77
    • Better health options
More energy and better digestive health
Reviewed in the United States on November 24, 2025 by BrendaE
    • Premium 4-in-1 Probiotic Prebiotic, Postbiotic & Digestive Enzymes for Men
A Solid Supplement, But Not as Effective as Hoped. I was really looking forward to trying this 4-in-1 supplement because the idea of combining probiotics, prebiotics, postbiotics, and digestive enzymes into one formula seemed convenient and potentially very effective. I’ve been focusing more on gut health lately and wanted a well-rounded product that could support digestion, immunity, and overall well-being. Unfortunately, while this supplement isn’t bad, it didn’t quite live up to my expectations. I took the recommended dose daily for several weeks. I did notice some mild improvements—mainly less bloating after meals and a slight increase in regularity. The enzymes seem to help with digestion, particularly after heavier meals, and I appreciated that there were no unpleasant side effects like gas or stomach discomfort, which can happen with some probiotics. The capsules are easy to swallow and don’t have any bad aftertaste. However, the results were pretty subtle. I was hoping for more noticeable changes in things like energy, mood, or even skin clarity (all things I’ve experienced with other high-quality probiotic supplements). Compared to other products I’ve used that cost the same or even a little less, the impact of this one was just okay. Also, it would’ve been helpful to have more transparency on the strains of probiotics included and their CFU count—those details matter for anyone who’s serious about their gut health. All in all, it’s a decent product that might work better for someone just starting with digestive health supplements or who doesn’t need a strong formula. I’ll finish the bottle, but I’m not sure I’d repurchase unless I don’t find something more effective in the same price range. There’s potential here, but for me, it didn’t quite deliver the premium experience the label suggests. ... show more
Reviewed in the United States on May 3, 2025 by Benjamin
    • Seems to be very effective!
It seems to be working very well! For the first time in my life, I've had 2 normal bowel movements within a week!
Reviewed in the United States on November 4, 2025 by Theresa A. Strakos

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