Search  for anything...

Ortho Home Defense Insect Killer for Indoor and Perimeter2, Controls Ants, Roaches, Spiders and More, 1 gal

  • Based on 10,333 reviews
Condition: New
Checking for the best price...
$9.42 Why this price?
Save $4.07 was $13.49

Buy Now, Pay Later


As low as $2 / mo
  • – 4-month term
  • – No impact on credit to apply
  • – Instant approval decision
  • – Secure and straightforward checkout

Ready to go? Add this product to your cart and select a plan during checkout.

Payment plans are offered through our trusted finance partners Klarna, Affirm, Afterpay, Zip, Apple Pay, and Google Pay. No-credit-needed leasing options through Acima may also be available at checkout.

Learn more about financing & leasing here.

Selected Option

Free shipping on this product

This item is eligible for return within 30 days of receipt

To qualify for a full refund, items must be returned in their original, unused condition. If an item is returned in a used, damaged, or materially different state, you may be granted a partial refund.

To initiate a return, please visit our Returns Center.

View our full returns policy here.


Availability: Only 1 left in stock, order soon!
Fulfilled by Amazon

Arrives Tuesday, Oct 27
Order within 21 minutes
Available payment plans shown during checkout

Protection Plan Protect Your Purchase
Checking for protection plans...

Style: Trigger


Size: 1 Pack


Features

  • Ortho Home Defense Insect Killer for Indoor & Perimeter2 kills the toughest home-invading insects, including ants, cockroaches, spiders, fleas, ticks, scorpions, earwigs, silverfish and periodical cicadas (as listed)
  • This insect killer spray provides a long-lasting bug barrier of up to 12 month protection against ants, roaches and spiders indoors on non-porous surfaces
  • Use this pest control spray indoors in kitchens and bathrooms or around doors and windows, and outdoors to the perimeter of foundations, patios, decks, garages or wherever insects are a recurring problem
  • Apply this bug killer anytime as a preventative treatment or after you see evidence of insect activity
  • This 1 gal. container of Ortho Home Defense Insect Killer for Indoor & Perimeter2 comes with convenient trigger sprayer for easy application

Description

Ortho Home Defense Insect Killer for Indoor & Perimeter2 kills common household bugs such as ants, beetles, centipedes, cockroaches, crickets, fleas, flies, millipedes, mosquitoes, moths, spiders, stink bugs, ticks, termites, periodical cicadas and more (as listed). This insect killer creates a bug barrier for up to 12 months protection against ants, roaches and spiders indoors on non-porous surfaces. In addition, the Invisi-Shield Technology formula gives off no fumes, dries clear and dries fast. Use this pest control product anytime as a preventative treatment or after you see evidence of insect activity for long lasting-control. Apply indoors in kitchens and bathrooms or around doors and windows, and outdoors to the foundation perimeters, patios, decks, garages and wherever insects are a recurring problem. For indoor surfaces, hold sprayer 12 inches from surface being sprayed and apply a 4-inch wide band, or use a 12-inch wide band when applying to a home perimeter. Area should be sprayed until slightly wet without soaking. People and pets may re-enter the treated area once sprays have dried. Trust Ortho to keep bugs out of your home.

Item Form: Aerosol


Liquid Volume: 1 gallons


Brand: Ortho


Target Species: Insects


Unit Count: 128 Fluid Ounces


Brand Name: Ortho


Unit Count: 128 Fluid Ounces


UPC: 071549022082


Global Trade Identification Number: 86


Included Components: Insect Repellents


Item Type Name: Home Defense Insect Killer


Manufacturer: The Scotts Company LLC


Model Number: 0220810


Part Number: 220810


Item Form: Aerosol


Target Species: Insects


Liquid Volume: 1 gallons


Frequently asked questions

If you place your order now, the estimated arrival date for this product is: Tuesday, Oct 27

Yes, absolutely! You may return this product for a full refund within 30 days of receiving it.

To initiate a return, please visit our Returns Center.

View our full returns policy here.

  • Klarna Financing
  • Affirm Pay in 4
  • Affirm Financing
  • Afterpay Financing
  • Zip Pay in 4
  • Financing through Apple Pay
  • Financing through Google Pay
Leasing options through Acima may also be available during checkout.

Learn more about financing & leasing here.

Top Amazon Reviews


  • Excellent value, and works like a charm. Been using for years.
Style: Trigger Size: 1 Pack
This is a very good quality bug spray. I use it indoors, and outdoors for a perimeter spray. It works extremely well against ants, and spiders. It has a bit of a smell to it especially when you do your whole house in one go at it. It dries about as fast as water, and the instructions are pretty simple to follow. This particular bottle of it has a top that you have to turn in order to get the flow to work. In addition to that you need to turn the tip on the sprayer. It basically works just like a regular spray bottle. There's no pumping required. I have been using this stuff for at least 20 years. This was a very good value for the amount that I got which is one gallon. One bottle really goes a long way. If you don't want it to dry up then you have to turn off the knob on top of the bottle. Otherwise if you don't use it very often then you will come back to it, and the straw will be clogged. I always pray about one or two rooms at a time and then vacate for a while until it dries up and smell goes away. If you do your whole house all in one day then you probably want to stay out of there for several hours. Basically move everything against the wall out of the way so that you can spray along the floor and wall. I also like to do this in window sills, and anywhere that I think a bug might find a home. Once it's dry, and the air clears out then it doesn't really leave a smell after that. It also does not stain carpet, and it's completely clear. It will not leave any residue that you can actually see. When you use it make sure that your pets aren't anywhere around it, and your kids too. It only works with crawling bugs unless you can find their nest. It will get rid of bees but you want to spray it when they're not around in the morning or late in the evening. If it's dark then they won't bother you. I'm going to give it five stars. ... show more
Reviewed in the United States on August 11, 2026 by MK

  • It works!
Style: Trigger Size: 1 Pack
Edit 3/19/23: The company replied to my concern & stated that the roaches will die in 24 hours & prevent from coming in. Honestly, I have not seen one roach since I used this - prob 3 weeks ago? I just wish they had changed the name to “within 24 hours or so” instead of “kills on contact,” - inaccurate description. Otherwise, I’m satisfied & think that it’s effective. Plus it has no smell so it makes me believe it’s greener than most chemicals. Who knows. I was excited to use this because it said it works on contact so I assumed it’s powerful. I put it to the rest & a tiny roach that I drenched, almost drowned in this still kept moving after maybe 2 minutes. I had to kill it & stopped waiting for it to work because the roach was on its way to a crevice. Did I do something wrong? I shake it really well. I’m thinking I got a watered down item??? I am so disappointed & I almost never write a bad review on anything. If Amazon want to look at my reviews, I’m pretty fair & forgiving. I really want this to work & I don’t know what else to get without baiting the roach & for me to see it dead in random places. It gives me the heebie jeebies. So I want to spray ‘em on contact with something POTENT! ... show more
Reviewed in the United States on February 26, 2023 by Lesley

  • Promising Start with Ortho Home Defense Insect Killer
Style: Trigger Size: 1 Pack
I recently purchased the Ortho Home Defense Insect Killer and have been using it for a short while. While it's still too early to make a definitive judgment, I'm already seeing promising results that warrant a positive review. The trigger sprayer that comes with the product is convenient and easy to use. It provides a consistent spray, ensuring even coverage across the surfaces I'm targeting. The non-staining and odor-free formula is a big plus, as I can apply it without worrying about leaving marks or unpleasant smells around my home. In terms of effectiveness, I've noticed a decrease in the insect activity around my home. While I can't say for certain that all the targeted pests are completely gone, the reduction in sightings of ants, cockroaches, and spiders is a positive sign. Fleas and ticks have also become less of an issue for my pets, which is a relief. The long-lasting control claim is something I'm looking forward to witnessing over time. If the product continues to deliver on this front, it will definitely solidify my positive impression. The 1-gallon size is generous and should last for a good amount of time, even with repeated applications. This makes the product a cost-effective solution for indoor and perimeter insect control. While it's too early to provide a final verdict, I'm optimistic about the Ortho Home Defense Insect Killer. If the positive trends I'm seeing continue, I'll certainly consider upgrading this review to a full 5 stars in the future. ... show more
Reviewed in the United States on August 20, 2023 by Kidus Tsige

  • Works great for palmetto bugs
Style: Trigger Size: 1 Pack
When I moved in to a new rental house, I was thrilled! Until I met the palmetto bugs of south carolina. They're big, spooky, and were everywhere outside. I had to get rid of them. I had little sticky traps before and I was changing the traps every few days just from how many of these there were. I began spraying this on my screen porch and immediately sprayed one of the palmettos, and in 10 seconds it flopped on its back dead. So far so good. I started establishing a perimeter around my porch and then slowly expanding the perimeter as I moved outwards. After about 30 minutes of spraying I wasnt even close to being through the bottle but I was satisfied with my coverage. I let it dry for an hour and I was literally amazed. 4 dead palmettos already. And I wasnt terrified of going outside on the porch to just enjoy the outdoors in fear of a giant skittering creature. I then moved to the front door and began spraying there as well, putting down a good perimeter again. I noticed there were no more spiders after a day as well. I've only seen one palmetto since which I chased down with the spray and reinforced my perimeter again about a week after initial application. It most definitely works For me, its worked on stinkbugs, palmetto bugs, ants and spiders. I'm no amazing pest controller and I know there have been some holes in my perimeter but I've just sprayed a little more when I find somewhere I've missed and this stuff has been great! I do need to start in on the source of these palmettos which is the space under my porch (I suspect) and potentially the crawl space under the house which I have no access to. But I can get under the porch with a longer sprayer and I'm confident that by the end of spring, I'll be palmetto free! ... show more
Reviewed in the United States on May 2, 2022 by D. Aurora

  • Great Product!
Style: Trigger Size: 1 Pack
Protects the home as described. We have used it for several years.
Reviewed in the United States on May 7, 2026 by Edwin D.

  • Second Time Purchase
Style: Trigger Size: 1 Pack
This stuff works great. Any time I have had bug invasions (mostly roaches and ants), I just spray some of this around the sightings, and the bugs soon show up - actually belly up! Works quickly and effectively. I bought this because it is pet and child friendly which was critical for me, so I am glad it works so well too. The last jug I bought seemed to last forever (actually I think I have a little bit left in it), but with summer here, I stocked up. The sprayer is different from the last jug, and I actually had to find the directions to install the nozzle on this one, but once that was done, no problem. Incidentally, the instructions are on a sticker pressed flat on the bottle, so it seems like a label. It actually peels off and gives product information as well as instructions to attach the nozzle. Pretty easy once you read the instructions. Really happy with this again. ... show more
Reviewed in the United States on June 23, 2023 by VSL

  • NOT For Huge Pest Issue
Style: Trigger Size: 1 Pack
I waited a while before doing this review, as they say that dramatic results wouldn't be instantaneous. Had some neighbors move in above me and not long after I started to see roaches in my apartment. After using those bug foggers multiple times with no success I moved on to this product. I used this all over my apartment, including inside the vents, behind appliances, inside the cabinets, even outside along my apartment. While I started to notice a decrease in the daily critters I saw, it didn't last long. They started to come back as if I had never sprayed it. It also doesn't kill on contact. Almost as if the roach only dies because I drowned it in the product. Needless to say, this may work better for other bugs. And maybe because the people above me may be swarming in roaches and they just keep coming back. Had to call for a professional pest control service, and I use the plug-ins in my outlets that are supposed to emit wavelengths that keep them away. So I suggest only using this product for minor PREVENTATIVE measures. Not infestations. ... show more
Reviewed in the United States on October 11, 2019 by Yaya

  • Effective spray, no complaints
Style: Trigger Size: 1 Pack
I obviously recommend leaving the room after you've sprayed it for at least an hour. The smell isn't horrible, but I didn't stick around to test it out. I used a mask when spraying the area and let it sit and dry before coming back. The spray itself says that it dries in minutes for quick re-entry, but my family is sensitive to certain odors so we wanted to play it safe. I primarily used the spray inside, and it is definitely non-staining! I found a roach and tested it out directly on the bug itself -- and, yes, it did kill the cockroach! Keep in mind that cockroaches are social insects that use their pheromones to communicate with others. Waiting for the roaches to run away one by one and kill them won't work as they'll be alerted to the danger. I paired this spray with roach tape and was able to capture 4 of them running from the sprayed area in just under an hour. We've been using this spray for nearly two months now and I am nowhere near to running out. Works great! ... show more
Reviewed in the United States on June 25, 2023 by Julia Sousa

Can't find a product?

Find it on Amazon first, then paste the link below.
Checking for best price...