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Nioxin Shampoo & Conditioner Liter Duo Sets | Prepacks with Pumps Included | Systems 1-4 | For Natural, Colored, & Damaged Hair with Light to Progressed Thinning | Strengthen & Boost Hair Density

  • Based on 1,225 reviews
Condition: New
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Availability: In Stock.
Fulfilled by Amazon

Arrives Sunday, Sep 7
Order within 18 hours and 42 minutes
Available payment plans shown during checkout

Style: System 2 | Natural Hair, Progressed Thinning


Product Benefits: Formulated with a powerful blend of ingredients to help nourish the hair root and strengthen the hair. See more


Item Form: Lotion


Brand: NIOXIN


Hair Type: Thin


Scent: Mint


Product Dimensions ‏ : ‎ 9 x 3 x 11 inches; 4.59 Pounds


Item model number ‏ : ‎ RY7-KS53


Best Sellers Rank: #6,609 in Beauty & Personal Care (See Top 100 in Beauty & Personal Care) #96 in Shampoo & Conditioner Sets


#96 in Shampoo & Conditioner Sets:


Customer Reviews: 4.7 4.7 out of 5 stars 1,225 ratings


Frequently asked questions

If you place your order now, the estimated arrival date for this product is: Sunday, Sep 7

Yes, absolutely! You may return this product for a full refund within 30 days of receiving it.

To initiate a return, please visit our Returns Center.

View our full returns policy here.

  • Klarna Financing
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  • Afterpay Financing
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  • Financing through Apple Pay
Leasing options through Acima may also be available during checkout.

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Top Amazon Reviews


  • a lifelong staple – cleanses, stimulates, and delivers results for overprocessed hair
Style: System 4 | Colored Hair, Progressed Thin...
I’ve been using Nioxin System 4 for years, and despite trying numerous other shampoos and conditioners, it remains a constant fixture in my shower routine. While I don’t use it daily, as overuse can be drying and slightly color-stripping, once a week, it’s exactly what overprocessed, thinning, or fragile hair needs to reset and thrive. Performance: System 4 is meticulously designed for chemically treated, noticeably thinning hair, and it delivers on its promise. It deeply cleanses the scalp, enhances circulation, and effectively removes buildup that clogs follicles. My hair and scalp always feel balanced, invigorated, and lighter after use. The shampoo and conditioner have a smooth and creamy texture, neither runny nor heavy. Over time, I’ve noticed a noticeable improvement in hair density and scalp comfort. Fragrance & Feel: The scent is fresh, clean, and slightly minty, with a salon-quality fragrance that’s pleasant and not overpowering. There’s a pleasant cooling sensation on the scalp, which enhances the effectiveness of the product. Packaging Details: I ordered the liter duo, and they arrived perfectly sealed, with two different colored pumps. This thoughtful detail is especially helpful when you’re washing your hair with eyes full of soap. Although it may seem small, not having to guess which bottle is which is a significant advantage. Having the pumps included, without having to beg for them in-store, is a big win. Everything was wrapped securely, ensuring no leaking or issues. Value: While prices have increased, this set still offers excellent value for the quality and quantity of products you receive. It provides true salon-grade scalp and hair therapy in large bottles that last for months. It’s not a trendy product; it’s a professional staple with a proven track record. Key Ingredients (System 4): • Peppermint Oil: Cooling and stimulating circulation. • White Tea Extract: Antioxidant support. • Nettle Root Extract: Soothing scalp. • Niacinamide & Biotin: Supporting hair strength. • Sodium Laureth Sulfate: Deep cleansing agent. • Menthol: Giving that signature tingle. Nioxin System 4 is a trusted, proven, and effective hair care product that delivers results every time. Whether you’re recovering from damage, breakage, or just need a weekly detox, this set is the product you keep around when your hair needs to get back on track. ... show more
Reviewed in the United States on June 4, 2025 by VanillaPepper

  • You can FEEL IT working. Amazing shampoo for thinning and dry hair!
Style: System 4 | Colored Hair, Progressed Thin...
The shampoo and conditioner smells amazing. Works great. My hair was really dry from dye jobs. And I was getting concerned. This has helped my hair so much in the short time that I have used it. Seriously worth the price and you can almost feel it working. Amazing shampoo and I would 100 percent suggest this to anyone looking to improve hair health. The amount of shampoo/conditioner will last me quite some time as well! ... show more
Reviewed in the United States on July 5, 2025 by Pkh4027

  • Very good product
Style: System 4 | Colored Hair, Progressed Thin...
I’ve been using this product since May. I love the smell and I do think it is beginning to help me with minor hair loss. I will buy this again.
Reviewed in the United States on June 27, 2025 by Becca

  • Great shampoo
Style: System 2 | Natural Hair, Progressed Thin...
I had to take some medication about 6 years ago that made my hair very thin and brittle. I searched for a while to find a shampoo that stopped the hair loss and made what little hair I have seem thicker. The shampoo did the trick. I use it every day and my hair looks thicker and I don’t notice hair falling out anymore. I highly recommend this if you’re having hair fall or very thin hair. ... show more
Reviewed in the United States on August 1, 2025 by Laurie J. Fitzgerald

  • Thicker, Healthier Hair – Worth Every Penny!
Style: System 2 | Natural Hair, Progressed Thin...
The Nioxin Shampoo & Conditioner Liter Duo is a game-changer for thinning hair! After just a few weeks, my hair feels stronger, fuller, and healthier. The formula is refreshing and doesn’t weigh my hair down. The included pumps make dispensing easy, and the liter size lasts a long time. Whether you have natural, colored, or damaged hair, this set is a must-try for boosting hair density. Highly recommend! ... show more
Reviewed in the United States on March 27, 2025 by Marc C.

  • Feels refreshing on your scalp
Style: System 4 | Colored Hair, Progressed Thin...
I purchased this back in February and have been using it religiously, about three times a week. I love the smell, and the lather. It makes your hair feel very clean. The conditioner is also very light weight and you dont need to use alot of it. Since most of us bought it due to, were losing hair more now than before. I can tell you that I have new hair growth underneath. (Picture, is kinda sloppy but that all new hair growth) . Im not getting any new hair on the top of my head. I used to have a lot of hair. Now I know ive lost more than half. It still looks ok. I just really had high hopes for this shampoo and conditioner. I probably will still buy it, because of all the pluses. I just wished it would grow more in my part.. Anyway, I do recommend it and I hope you have better results on top than I did.. ... show more
Reviewed in the United States on June 27, 2025 by FeelinSexi@58 FeelinSexi@58

  • Love this shampoo!
Style: System 4 | Colored Hair, Progressed Thin...
Great shampoo. Leaves your scalp feeling tingly.
Reviewed in the United States on July 27, 2025 by Jennifer Grin

  • The large bottle last 4-5 months before you have to reorder the product.
Style: System 1 | Natural Hair, Light Thinning
If you have thin hair this product make your hair look fuller and shinier and healthier. It's a good product. I recommend anyone who has thin hair to give it a try.
Reviewed in the United States on May 14, 2025 by Barbara J Nearing

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