Search  for anything...
Nature's Way

Probiotic Pearls Acidophilus Once Daily Probiotic Supplement, 1 Billion Live Cultures, Survives Stomach Acid, No Refrigeration, 90 Softgels (Packaging May Vary)

  • Based on 6,868 reviews
Condition: New
Checking for the best price...
$27.30 Why this price?
Save $10.19 was $37.49

Buy Now, Pay Later

As low as $6 / mo
  • – 4-month term
  • – No impact on credit to apply
  • – Instant approval decision
  • – Secure and straightforward checkout

Ready to go? Add this product to your cart and select a plan during checkout.

Payment plans are offered through our trusted finance partners Klarna, Affirm, Afterpay, Apple Pay, and PayTomorrow. No-credit-needed leasing options through Acima may also be available at checkout.

Learn more about financing & leasing here.

Selected Option

Free shipping on this product

Non-returnable due to Food safety reasons

View our full returns policy here.

Availability: In Stock.
Fulfilled by Amazon
Arrives Friday, Mar 27
Order within 4 hours and 47 minutes
Available payment plans shown during checkout
Protection Plan Protect Your Purchase
Checking for protection plans...

Recently Viewed

Size: 90 Count (Pack of 1)


Pattern Name: Acidophilus


Features

  • A daily probiotic for digestive health: probiotic pearls acidophilus contains 2 strains and 1 billion cultures in a convenient, once-daily softgel that's small and easy to swallow. This daily probiotic formula promotes daily protection against occasional gas, bloating and constipation.
  • Product Note: Exposure to heat or sunlight may lead to melting/damage of product. Hence customers are expected to be available during the product delivery
  • Two strains for digestive balance: taking probiotic pearls acidophilus provides L. Acidophilus for the small intestine and B. Longum for the large intestine (colon) to help promote digestive balance and colon health, support your body's immune defense and protect against occasional gas, bloating and constipation.
  • The smarter probiotic: probiotic pearls acidophilus uses an advanced triple-layer soft gel that protects probiotics from heat, air, moisture and stomach acid to maximize survival and delivery to the intestine.
  • Probiotic pearls acidophilus: requires No refrigeration. This product is gluten-free and contains no sugar, salt, yeast, wheat, corn, artificial colors, flavors or preservatives.
  • Serving recommendation: take one (1) softgel daily. May be taken with or without food. Do not chew or crush. If taking any medications, consult a healthcare professional before use. Other Ingredients- palm Oil, fish gelatin (tilapia), glycerin, soy lecithin, pectin, contains Milk, soy and fish (tilapia)
  • These statements have not been evaluated by the Food & Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.

Description

Nature's Way Acidophilus Probiotic Pearls deliver Lactobacillus plus Bifidobacterium cultures to support immune and colon health, and digestive comfort. A triple-layer coating guards each softgel against heat, air, moisture, and stomach acid, allowing live microorganisms to reach the small intestine intact. This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Is Discontinued By Manufacturer ‏ : ‎ No


Product Dimensions ‏ : ‎ 1.6 x 4.3 x 4.7 inches; 1.44 ounces


Item model number ‏ : ‎ 4299


Department ‏ : ‎ Health and Beauty>Health and Wellness


Date First Available ‏ : ‎ April 21, 2004


Manufacturer ‏ : ‎ Enzymatic Therapy


Best Sellers Rank: #9,099 in Health & Household (See Top 100 in Health & Household) #49 in Acidophilus Nutritional Supplements #1,003 in Sales & Deals


#49 in Acidophilus Nutritional Supplements:


#1,003 in Sales & Deals:


Brand Name: Nature's Way


Item Form: Softgel


Product Benefits: Immune Health Support


Age Range Description: Adult


Container Type: Box


Dosage Form: Softgel


UPC: 763948042999


Manufacturer: Enzymatic Therapy


Global Trade Identification Number: 99


Unit Count: 90 Count


Item Weight: 0.09 Pounds


Item Dimensions: 1.6 x 4.3 x 4.7 inches


Number of Items: 1


Total Servings Per Container: 90


Flavor: Unflavored


Material Features: Gluten Free, No Artificial Colors, No Artificial Flavors, No Artificial Preservatives, Sugar Free, Yeast Free


Specific Uses For Product: Constipation, Digestive Balance, Intestinal Balance, Probiotics


Allergen Information: Gluten Free, Wheat Free


Frequently asked questions

If you place your order now, the estimated arrival date for this product is: Friday, Mar 27

This item is non-returnable:

Non-returnable due to Food safety reasons

View our full returns policy here.

  • Klarna Financing
  • Affirm Pay in 4
  • Affirm Financing
  • Afterpay Financing
  • PayTomorrow Financing
  • Financing through Apple Pay
Leasing options through Acima may also be available during checkout.

Learn more about financing & leasing here.

Similar Products

Top Amazon Reviews

    • Great product that works
Small, no refrigeration needed, been using for years. I take it with my first meal of the day but others may choose to take it differently. Has helped any & all of my stomach upsets. It's the acidophilus that works for me.
Reviewed in the United States on October 26, 2025 by S Price
    • Worked for me
Good product they have helped my gut health over the years
Reviewed in the United States on January 21, 2026 by GabeKentucky
    • Probiotics for the gut
Probiotics for the gut. Works wonderfully.
Reviewed in the United States on February 1, 2026 by Pam K.
    • Worth a try
Review Image by K K
I have been buying/using Nature’s Way pearls for years with efficacy comparable to higher priced options. I switch up the different varieties to get the various strains for gut health. Noticeable improvement with sugar cravings decreased. I started my “sugarholic” teen on these and it made a difference in her desire for sugar. It’s worth a try. Be consistent for a month to see if you have results. ... show more
Reviewed in the United States on January 7, 2026 by K K
    • I think they are working
The probiotic pearls are easy to swallow, not sure how they are working. I have been taking them for a couple weeks and they seem to make a differance though not dramatic.
Reviewed in the United States on September 25, 2025 by RLE
    • Effective!!!!! But guess what else it does!
With the risk of explaining a few of the taboo subjects of the female system, I will explain up front that my review isn't primarily about digestion and improved skin condition like other reviewers reported...... With that said, I was on the market to solve a little problem that would eliminate constant requests to the doctor for Fluconazole and Monistat products. All women produce yeast, some produce a bit much....thus the need for a better solution. Yogurt is the #1 most recommended food used to balance the body's natural production, so you are told "Eat more yogurt". Well, sure, why not?? However, I'm not huge fan of yogurt, nor do I intend to eat it 2 times a day or more. If that worked, I wouldn't be posting this review. When I searched and found this product, I was skeptical because no one mention it's effectiveness in balancing the body's natural production of yeast. Perhaps it's really just too much a taboo subject to actually post a review on? I'm not sure. After staring at this product in my cart for a few weeks, I finally gave in and bought it. It's a little expensive, but I decided it would be worth the money, if it works. I am happy to say that it does work! After two weeks of consistently taking this product, I'm pleased that I've found a much simpler solution than downing yogurt constantly or making embarrassing trips to the store. Plus, I found that it also does what the other reviewers reported on: regulated digestion and improved skin condition. The last one I didn't believe, but I didn't care because that wasn't what I bought it for. However, improved skin tone and fewer blemishes is a nice perk too! This product really should be sold in stores, made easily available. I'm just not sure which department it would best be marketed in (health & beauty, dairy, or feminine department?) but I intend to continue using it. 5 stars for this product. It does exactly what it promises to do. I'm happy to find a solution for really multiple reasons! ... show more
Reviewed in the United States on March 28, 2013 by M. Hudson
    • Small, coated & wonderful! No running out or driving from store to store to buy!
My daughter and I take these daily to deal with digestive issues (me) and as a counter balance to one of her medications. The pills are tiny and coated so no bitter taste in my mouth or having to swallow a horse pill! They do not have to be stored in the refrigerator which is do nice as mine is forever too full as it is. I like that this helps move things along daily. Not trying to keep extra weight on me in my weight loss journey nor develop colon cancer from not going as often as I need to! I ordered 30 to start (try out) but signed up for 90 so I don’t run out or have to keep ordering the smaller packs. Each pill is in its own little packet. Easy to open tiny packets. Easy to swallow. I like these better than the ones I bought from a different store (different brand). I was always running out of them and the stores (Target, Dollar General, Schnucks) didn’t carry an adequate supply. I need a supply I can count on do I am on the auto deliver plan. No more running out for me and my daughter! No more driving from store to store hoping they will have them in stock but finding they don’t! ... show more
Reviewed in the United States on July 4, 2021 by Chef Moi!
    • Great for gut health
Love these. Great for traveling. No refrigeration needed.
Reviewed in the United States on February 24, 2026 by Elizabeth Jeffries, Executive Coach, Author

Can't find a product?

Find it on Amazon first, then paste the link below.
Checking for best price...