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Nature's Way

Nature's Way Probiotic Pearls Acidophilus Softgels, 1 Billion CFU, 90 ct | Supports Digestive Balance & Gut Health*, Reduces Occasional Constipation and Bloating*, 1 Billion CFU, No Refrigeration

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Availability: In Stock.
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Arrives Thursday, Jul 30
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Size: 90 Count (Pack of 1)


Features

  • Digestive, Immune, and Colon Health Support* - Formulated with HOWARU Lactobacillus acidophilus NCFM and Bifidobacterium longum BB536 to promote digestive balance and support immune and colon health, while helping protect against occasional bloating.*
  • Advanced Triple-Layer Coating - Each pearl is protected by an advanced triple-layer coating designed to shield against heat, air, moisture, and stomach acid, helping live cultures survive the journey to the intestines where they're needed most.*
  • No Refrigeration Required - Probiotic Pearls are small, easy to swallow, and designed for life on the go. No refrigeration needed, so you can keep them in your bag, at your desk, or anywhere that fits your routine.
  • How to Take - Adults swallow 1 softgel daily. May be taken with or without food. Do not chew or crush. Contains no salt, wheat, soy, or artificial colors. Contains milk and fish (tilapia).
  • Over 50 Years of Expertise - At Nature's Way, we believe nature is the ultimate problem solver. For over 50 years, we have looked to the natural world for inspiration. Our vitamins and supplements are formulated to help you find your way to wellness.

Description

When it comes to supporting your digestive health, keeping it simple and making it a daily habit can make all the difference. Nature's Way Probiotic Pearls Acidophilus is formulated with two probiotic strains-HOWARU Lactobacillus acidophilus NCFM and Bifidobacterium longum BB536-to promote digestive balance, support immune and colon health, and help protect against occasional bloating, constipation, and digestive discomfort. HOWARU is a registered trademark of IFF and is used under license.Each tiny pearl delivers 1 billion CFU of active Lactobacillus and Bifidobacterium cultures in a once- daily softgel. What makes Probiotic Pearls stand out is their advanced triple- layer coating, engineered to protect each softgel from heat, air, moisture, and stomach acid. This protective barrier helps live cultures survive the journey through the digestive tract and reach the intestines, where probiotic support is needed most.Convenience is built into every detail. Probiotic Pearls are small and easy to swallow, making them a practical choice for adults who want consistent daily probiotic support without the hassle of refrigeration. Whether you're at home, at the office, or traveling, these pearls go where you go. Store at room temperature and avoid excessive heat and direct sunlight.Probiotic Pearls Acidophilus contains no salt, wheat, soy, or artificial colors. Contains milk and fish (tilapia).Adults swallow 1 softgel daily. May be taken with or without food. Do not chew or crush.These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Is Discontinued By Manufacturer ‏ : ‎ No


Product Dimensions ‏ : ‎ 1.6 x 4.3 x 4.7 inches; 1.44 ounces


Item model number ‏ : ‎ 04299


Department ‏ : ‎ Health and Beauty>Health and Wellness


Date First Available ‏ : ‎ April 21, 2004


Manufacturer ‏ : ‎ Nature's Way


Best Sellers Rank: #9,093 in Health & Household (See Top 100 in Health & Household) #41 in Acidophilus Nutritional Supplements #1,096 in Sales & Deals


#41 in Acidophilus Nutritional Supplements:


#1,096 in Sales & Deals:


Brand Name: Nature's Way


Primary Supplement Type: Probiotic


Item Form: Softgel


Product Benefits: Digestive Health Support


Age Range Description: Adult


Container Type: Box


Dosage Form: Softgel


Model Name: Probiotic Pearls® Acidophilus / 90 softgels


Supplement Formulation: Individual Supplement


UPC: 763948042999


Manufacturer: Nature's Way


Global Trade Identification Number: 99


Model Number: 04299


Manufacturer Part Number: 04299


Unit Count: 90.0 Count


Item Weight: 0.09 Pounds


Item Dimensions: 1.6 x 4.3 x 4.7 inches


Number of Items: 1


Total Servings Per Container: 90.0


Flavor: Unflavored


Special Ingredients: Acidophilus


Material Features: No Artificial Colors


Specific Uses For Product: Constipation, Digestive Balance, Intestinal Balance, Probiotics


Allergen Information: Gluten Free, Wheat Free


Color: Pearl


Frequently asked questions

If you place your order now, the estimated arrival date for this product is: Thursday, Jul 30

This item is non-returnable:

Non-returnable due to Food safety reasons

View our full returns policy here.

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Top Amazon Reviews

    • A daily essential for digestive health
Size: 30 Count (Pack of 1)
I've been taking these probiotic pearls for years now, and they've made a real difference in my digestive routine. I'm someone who used to struggle with irregularity, but these have kept me regular and consistent. The pearls are easy to swallow - much smaller than a lot of probiotic capsules I've tried. I take one every morning with breakfast and it's become part of my routine. No weird aftertaste or stomach upset, they just do their job quietly and effectively. What I appreciate most is the consistency. Some products work for a few weeks and then seem to lose effectiveness, but these have been reliable for me year after year. I notice when I run out or forget to take them for a few days - things just don't move as smoothly. I've tried other probiotic brands when these were out of stock, but I always come back to these pearls. They're the only ones that have worked this well for me long-term. The price is reasonable, especially when you consider I've been using them for years and they've never let me down. If you're dealing with digestive issues or just want to maintain better regularity, I'd definitely recommend giving these a try. They've earned a permanent spot in my daily routine! ... show more
Reviewed in the United States on February 9, 2026 by Rob & Natalie Martinez
    • Best Probiotic Gut Help
Size: 90 Count (Pack of 1)
I love these probiotics. Anytime I have to take antibiotics, I take one of these along with it. It helps prevent stomach upset and irritation. These are so easy to take because they are super tiny. They're a little on the pricey side but definitely worth it. You do get 30 in the box so I feel like it's a great value for your money. This is my favorite brand to use. I can't always find these at my local store so I appreciate being able to order them from Amazon. I highly recommend this probiotic supplement. ... show more
Reviewed in the United States on March 4, 2026 by S Rocky
    • Works wonderfully
Size: 90 Count (Pack of 1)
I have been taking for several years & at 62 it keeps my gut healthy. I no longer have bowel issues Cost effective & doesn't irritate my stomach.
Reviewed in the United States on April 1, 2026 by Amazon Customer
    • Use this daily
Size: 90 Count (Pack of 1)
It's a great product and it is great to have it sent automatically so I always have on hand
Reviewed in the United States on July 10, 2026 by Bonnie Guthrie
    • Love / Hate Relationship with these little pearls...
Size: 90 Count (Pack of 1)
I have a love hate relationship with these little pearls. I gave 4 stars because they're somewhere between 3 and 5. Let me explain... **TMI WARNING IN THE FOLLOWING**... Scroll to the bottom to skip the TMI portion with backstory and just get the nitty gritty! I had to start taking a blood pressure pill, which I'd never had to take before. I took one (Clonidine) and it didn't have any sort of digestive issue that I could tell but it made me extremely tired (note, it *is* a sedative) and loopy, and I had a lot of trouble focusing. I talked to the doctor about how the side effects were affecting me at work and so forth, and he prescribed me Amlodipine Besylate. It was much better, except that I became badly constipated. Despite not being one, it has a lovely diuretic effect on me making me go too much number 1 and not enough number 2. I talked to the doctor again. I had recently also changed my diet and went from having stomach aches all the time to never. This was a mixed bag because the problem is that my stomach probably has acquired the same issue as why you shouldn't take a stimulant laxative all the time - too many stomach aches seem to have made my body reliant on a stomach ache to have to go. However, I also had made similar dietary changes as when my digestion had regulated previously and at that time, everything seemed to "be moving" really well even without stomach aches. But despite my dietary changes, it wasn't enough to combat the effects of the Amlodipine. He told me I could take Miralax or the equivalent or Dulcosate Sodium, even every day if needed since they are both stimulant-free laxatives. Stool softeners. Things started to improve and I started to go every other day or so. I decided to buy these though, thinking maybe they would help (after all, I've taken plenty of laxatives and never a probiotic, I don't eat much sauerkraut and no kefir, just yogurt) and maybe I could even go off the dulcosate sodium and have all the miraculous effects that people swear by probiotics for. Nope! These made me feel constipated all over again, AND gave me more gas than I was having. Brilliant! I figured, maybe that was some random effect of my system adjusting to them but... nope. I'm over half done with one blister pack, I've taken them for a couple weeks now, and the results have remained the same. Note, I did NOT stop taking the dulcosate sodium tablets (250mg 1x/day) but suddenly it seemed to negate the benefit. I decided to keep taking them in the beginning, and although I've considered stopping a couple times because it's very irritating, but here's why I've stayed on them - when I am able to go, I go a LOT. I'm not straining, I don't have diarrhea, I just have those stools that they talk about in that infomercial that are like the guy who has the daughter who poops the length of his arm. I feel like I'm pooping out my large intestine each time. But, on the dulcosate sodium *only*, I was not straining but not always able to go much. More frequently, but not too much (better than "little marble size" though still). ***END TMI (for the most part)*** Ultimately, they have a negative effect on me of <TMI>constipation</TMI> which hit pretty much immediately (day 1), but they also have a positive effect of <TMI>going more</TMI>. I would suggest them, but I would recommend keeping your expectations reasonable. For some people they seem to work extremely well. But for others, like me, it's give and take. I think that a different kind with additional strains, and perhaps no acidophilus, The positive effect just *slightly* edges out the negative. Also, when it is time to go, it hits pretty suddenly despite not having a stomach issue. I'd say it's really up to your body. Though, it's possible that if you do have issues with diarrhea, they might be helpful? For the price it's worth a shot. They're in a blister pack and only pebble sized so if you decide you don't want them, give the rest to a neighbor or something and try something else like I probably will in the future. ... show more
Reviewed in the United States on August 29, 2016 by Heather
    • Works!
Size: 90 Count (Pack of 1)
I can tell a big difference in digestion and “regularity” when I take these
Reviewed in the United States on May 25, 2026 by TJ Geeka
    • Effective!!!!! But guess what else it does!
Size: 90 Count (Pack of 1)
With the risk of explaining a few of the taboo subjects of the female system, I will explain up front that my review isn't primarily about digestion and improved skin condition like other reviewers reported...... With that said, I was on the market to solve a little problem that would eliminate constant requests to the doctor for Fluconazole and Monistat products. All women produce yeast, some produce a bit much....thus the need for a better solution. Yogurt is the #1 most recommended food used to balance the body's natural production, so you are told "Eat more yogurt". Well, sure, why not?? However, I'm not huge fan of yogurt, nor do I intend to eat it 2 times a day or more. If that worked, I wouldn't be posting this review. When I searched and found this product, I was skeptical because no one mention it's effectiveness in balancing the body's natural production of yeast. Perhaps it's really just too much a taboo subject to actually post a review on? I'm not sure. After staring at this product in my cart for a few weeks, I finally gave in and bought it. It's a little expensive, but I decided it would be worth the money, if it works. I am happy to say that it does work! After two weeks of consistently taking this product, I'm pleased that I've found a much simpler solution than downing yogurt constantly or making embarrassing trips to the store. Plus, I found that it also does what the other reviewers reported on: regulated digestion and improved skin condition. The last one I didn't believe, but I didn't care because that wasn't what I bought it for. However, improved skin tone and fewer blemishes is a nice perk too! This product really should be sold in stores, made easily available. I'm just not sure which department it would best be marketed in (health & beauty, dairy, or feminine department?) but I intend to continue using it. 5 stars for this product. It does exactly what it promises to do. I'm happy to find a solution for really multiple reasons! ... show more
Reviewed in the United States on March 28, 2013 by M. Hudson
    • Did a good job
Size: 90 Count (Pack of 1)
My mistake he did a good job. It looked like he initially put it by the front door, but realized and put it in the garage. Thank you
Reviewed in the United States on May 30, 2026 by Ron Kainec

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