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Nature's Way Probiotic Pearls Acidophilus, Supports Digestive Balance & Gut Health, Reduce Occasional Constipation and Bloating*, 1 Billion Cultures, 90 Softgels

  • Based on 6,868 reviews
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Availability: In Stock.
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Arrives Tuesday, May 19
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Size: 90 Count (Pack of 1)


Pattern Name: Acidophilus


Features

  • Acidophilus Probiotic Pearls contains 2 Lactobacillus and Bifidobacterium strains plus 1 billion cultures in a once-daily softgel that's small, easy to swallow. This daily probiotic formula helps with occasional bloating, constipation, and digestive discomfort*
  • Taking Acidophilus Probiotic Pearls provides active Lactobacillus and Bifidobacterium cultures to help promote digestive balance, support colon and immune health, and supplements for digestive health*
  • Adults take 1 softgel daily. Small probiotic pearls are easy to swallow and conveniently sized to take anywhere, with no refrigeration required
  • Contains no salt, wheat, soy, or artificial colors. Contains milk, and fish (Tilapia)
  • At Natures Way, we believe nature is the ultimate problem solver. For over 50 years, we have looked to the natural world for inspiration. Our quality vitamins and supplements are formulated to help you find your way to wellness

Description

Nature's Way Probiotic Pearls Acidophilus deliver Lactobacillus plus Bifidobacterium cultures to support immune and colon health, and digestive comfort. A triple-layer coating guards each softgel against heat, air, moisture, and stomach acid, allowing live microorganisms to reach the small intestine intact.This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Is Discontinued By Manufacturer ‏ : ‎ No


Product Dimensions ‏ : ‎ 1.6 x 4.3 x 4.7 inches; 0.71 ounces


Item model number ‏ : ‎ 04299


Department ‏ : ‎ Health and Beauty>Health and Wellness


Date First Available ‏ : ‎ April 21, 2004


Manufacturer ‏ : ‎ Nature's Way


Best Sellers Rank: #10,445 in Health & Household (See Top 100 in Health & Household) #50 in Acidophilus Nutritional Supplements #1,076 in Sales & Deals


#50 in Acidophilus Nutritional Supplements:


#1,076 in Sales & Deals:


Brand Name: Nature's Way


Item Form: Softgel


Product Benefits: Nutritional Support


Age Range Description: Adult


Container Type: Box


Dosage Form: Softgel


Model Name: Probiotic Pearls® Acidophilus


UPC: 763948042999


Manufacturer: Nature's Way


Global Trade Identification Number: 99


Manufacturer Part Number: 04299


Model Number: 04299


Unit Count: 90 Count


Item Weight: 0.02 Kilograms


Item Dimensions: 1.6 x 4.3 x 4.7 inches


Number of Items: 1


Total Servings Per Container: 90


Flavor: Unflavored


Special Ingredients: Probiotic


Material Features: No Artificial Colors


Specific Uses For Product: Constipation, Digestive Balance, Intestinal Balance, Probiotics


Allergen Information: Gluten Free, Wheat Free


Frequently asked questions

If you place your order now, the estimated arrival date for this product is: Tuesday, May 19

This item is non-returnable:

Non-returnable due to Food safety reasons

View our full returns policy here.

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Top Amazon Reviews


  • Best Probiotic Gut Help
I love these probiotics. Anytime I have to take antibiotics, I take one of these along with it. It helps prevent stomach upset and irritation. These are so easy to take because they are super tiny. They're a little on the pricey side but definitely worth it. You do get 30 in the box so I feel like it's a great value for your money. This is my favorite brand to use. I can't always find these at my local store so I appreciate being able to order them from Amazon. I highly recommend this probiotic supplement. ... show more
Reviewed in the United States on March 4, 2026 by S Rocky

  • Works wonderfully
I have been taking for several years & at 62 it keeps my gut healthy. I no longer have bowel issues Cost effective & doesn't irritate my stomach.
Reviewed in the United States on April 1, 2026 by Amazon Customer

  • The BEST!
They are great! Easy to take!
Reviewed in the United States on March 11, 2026 by Doug Voight

  • Great product that works
Small, no refrigeration needed, been using for years. I take it with my first meal of the day but others may choose to take it differently. Has helped any & all of my stomach upsets. It's the acidophilus that works for me.
Reviewed in the United States on October 26, 2025 by S Price

  • Probiotics for the gut
Probiotics for the gut. Works wonderfully.
Reviewed in the United States on February 1, 2026 by Pam K.

  • Love / Hate Relationship with these little pearls...
I have a love hate relationship with these little pearls. I gave 4 stars because they're somewhere between 3 and 5. Let me explain... **TMI WARNING IN THE FOLLOWING**... Scroll to the bottom to skip the TMI portion with backstory and just get the nitty gritty! I had to start taking a blood pressure pill, which I'd never had to take before. I took one (Clonidine) and it didn't have any sort of digestive issue that I could tell but it made me extremely tired (note, it *is* a sedative) and loopy, and I had a lot of trouble focusing. I talked to the doctor about how the side effects were affecting me at work and so forth, and he prescribed me Amlodipine Besylate. It was much better, except that I became badly constipated. Despite not being one, it has a lovely diuretic effect on me making me go too much number 1 and not enough number 2. I talked to the doctor again. I had recently also changed my diet and went from having stomach aches all the time to never. This was a mixed bag because the problem is that my stomach probably has acquired the same issue as why you shouldn't take a stimulant laxative all the time - too many stomach aches seem to have made my body reliant on a stomach ache to have to go. However, I also had made similar dietary changes as when my digestion had regulated previously and at that time, everything seemed to "be moving" really well even without stomach aches. But despite my dietary changes, it wasn't enough to combat the effects of the Amlodipine. He told me I could take Miralax or the equivalent or Dulcosate Sodium, even every day if needed since they are both stimulant-free laxatives. Stool softeners. Things started to improve and I started to go every other day or so. I decided to buy these though, thinking maybe they would help (after all, I've taken plenty of laxatives and never a probiotic, I don't eat much sauerkraut and no kefir, just yogurt) and maybe I could even go off the dulcosate sodium and have all the miraculous effects that people swear by probiotics for. Nope! These made me feel constipated all over again, AND gave me more gas than I was having. Brilliant! I figured, maybe that was some random effect of my system adjusting to them but... nope. I'm over half done with one blister pack, I've taken them for a couple weeks now, and the results have remained the same. Note, I did NOT stop taking the dulcosate sodium tablets (250mg 1x/day) but suddenly it seemed to negate the benefit. I decided to keep taking them in the beginning, and although I've considered stopping a couple times because it's very irritating, but here's why I've stayed on them - when I am able to go, I go a LOT. I'm not straining, I don't have diarrhea, I just have those stools that they talk about in that infomercial that are like the guy who has the daughter who poops the length of his arm. I feel like I'm pooping out my large intestine each time. But, on the dulcosate sodium *only*, I was not straining but not always able to go much. More frequently, but not too much (better than "little marble size" though still). ***END TMI (for the most part)*** Ultimately, they have a negative effect on me of <TMI>constipation</TMI> which hit pretty much immediately (day 1), but they also have a positive effect of <TMI>going more</TMI>. I would suggest them, but I would recommend keeping your expectations reasonable. For some people they seem to work extremely well. But for others, like me, it's give and take. I think that a different kind with additional strains, and perhaps no acidophilus, The positive effect just *slightly* edges out the negative. Also, when it is time to go, it hits pretty suddenly despite not having a stomach issue. I'd say it's really up to your body. Though, it's possible that if you do have issues with diarrhea, they might be helpful? For the price it's worth a shot. They're in a blister pack and only pebble sized so if you decide you don't want them, give the rest to a neighbor or something and try something else like I probably will in the future. ... show more
Reviewed in the United States on August 29, 2016 by Heather

  • Great for gut health
Love these. Great for traveling. No refrigeration needed.
Reviewed in the United States on February 24, 2026 by Elizabeth Jeffries, Executive Coach, Author

  • Worked for me
Good product they have helped my gut health over the years
Reviewed in the United States on January 21, 2026 by GabeKentucky

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