HPN NAD3 Clinical NAD+ Booster, Cellular Health & Natural Energy - NAD Supplement for Healthy Aging, Metabolic Support, NRF2 & Longevity, Nicotinamide Riboside & NMN Alternative, 60ct, 30-Day Supply
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Availability:
In Stock.
Arrives
Saturday, Sep 20
Features
- WHAT IS NAD? - Nicotinamide adenine dinucleotide, or NAD+, is a coenzyme found in all living cells. It's a key component for the fundamental biological processes that make life possible. The problem is, as we age, NAD+ levels start to decline. Recent studies have verified there are tremendous health benefits to boosting NAD+
- BENEFITS OF NAD(3) - NAD(3) impacts all the key areas of cell health: It boosts NAD+ the crucial co-enzyme for Mitochondrial function. Activates Sirtuins, the healthy-aging and survival protein. Increases Telomerase activity to protect DNA. And influences NLRP3 expression to control cellular health
- THE WORLDS MOST EFFECTIVE NAD+ BOOSTER The studies are in & the research is very clear, while nicotinamide riboside is effective, it is not the best cell health product on the market. NAD(3) has advanced the science of NR - and revolutionized health from within
- THE NEXT EVOLUTION OF HPNs BEST SELLING PRODUCT - In 2013, High Performance Nutrition released a product that changed everything we thought we knew about anti aging & longevity; NAD(3) is the next, clinically superior evolution
- INDEPENDENTLY TESTED BY THE BSCG - NAD(3) is made in the USA with NSF cGMP certified manufacturing and independently tested for guaranteed purity and quality with every bottle
Brand: HPN
Flavor: Unflavored
Unit Count: 60.00 Count
Item Form: Capsule
Item Weight: 0.15 Pounds
Product Benefits: Anti-Aging, Detoxing, Energy Management
Age Range (Description): Adult
Package Information: Bottle
Number of Items: 60
Servings per Container: 30
Is Discontinued By Manufacturer : No
Package Dimensions : 5.47 x 2.72 x 2.68 inches; 2.47 ounces
Item model number : 9649671
Date First Available : June 20, 2014
Manufacturer : HPN
Best Sellers Rank: #13,973 in Health & Household (See Top 100 in Health & Household) #343 in Blended Vitamin & Mineral Supplements
#343 in Blended Vitamin & Mineral Supplements:
Customer Reviews: 4.3 4.3 out of 5 stars 4,022 ratings
Frequently asked questions
If you place your order now, the estimated arrival date for this product is:
Saturday, Sep 20
This item is non-returnable:
Non-returnable due to Food safety reasons
View our full returns policy here.
Non-returnable due to Food safety reasons
View our full returns policy here.
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Top Amazon Reviews
This is my main supplement for energy and mental clarity. I take this every day and I can feel a dramatic difference when I don’t take it. I have used many other NAD supplements and this is by far my favorite. Just solid energy and mental clarity. I trust this brand to other supplements as well.
Reviewed in the United States on July 25, 2025 by Christi L Haley Stover Christi L Haley Stover
Great product at a great price!
Reviewed in the United States on August 21, 2025 by Tom Rauscher
I'm not sure if it was Niagen or PQQ or Astaxanthin or pterostilbene I was taking, or the combination of them, but mind you I went for a run one day. The first time in over 6 months. I literally ran and ran and ran and ran. I could not get tired. I could not. I even threw a few sprints in during my run, but I could not get tired at all. Not even close. It was the weirdest feeling in my life. Weirdest good feeling. I didn't feel edgy or over stimulated, only normal and the fact that my run of 4 plus miles didn't prove to do anything to me whereas normally 2 miles would have me huffing and puffing. I guess it was a good feeling and overall I feel pretty good on Niagen. I'm not really sure if it did much, but I think it did. I mean I couldn't get tired at all. I'm sure it was doing something. I haven't really gone for a run since nor have I been taking Niagen religiously so I can't say much more. I usually pop 250 mg when I start feeling crummy, I think it works to pick me back up. I'm scared to take more because I feel like I'm just swallowing dollar bills. I had taken it for a week straight before I went said run. Other than that run, I couldn't tell much difference...I slept just fine though during the day time I was extremely detail oriented and much more particular than normal, but I attribute that to PQQ (which is also a miracle supplement). Anyways, 4 stars because it cost a fortune. Comeon guys lower the price so the world can enjoy this supplement. I really believe David Sinclair is on to something and Niagen was one of his recent discoveries as well as pterostilbene. I'm reluctant to buy more due to the exorbitant price.
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Reviewed in the United States on January 27, 2015 by SurferDude
I’ve been taking this NAD+ supplement for a few weeks and can really feel the difference. My energy is steady, my focus lasts longer through the day, and I don’t hit that afternoon slump anymore. Great addition to my routine.
Reviewed in the United States on August 21, 2025 by Amazon Customer
I am a 65 year old female who has had cancer twice, and have been in remission from stage 4 metastatic cancer for 11 years, due in part I believe to a regimen of supplements including resveratrol, quercetin, Vitamin C, Vitamin D3, and many others. I also walk 3 miles per day, and have tried to avoid sugar and refined carbs for much of that time. Throughout the years I have been following anti-aging and anti-cancer research, as a curious layperson. I have explored writings and videos by David Sinclair of Harvard, Leonard Guarente of MIT, and others, leading me to the recent reports on the postulated benefits to humans of NAD precursor, Nicotinimide Riboside. Leonard Guarente himself takes it, according to his Elyseum website. I started taking the recommended dose in early February, 2015, and can report some positive results, although I believe the dosage level is critical and probably varies widely, depending on one’s age and health status. My experience has been that the prescribed dose of 250 mg. is simply too much. It revved me up, but the rebound effect was very noticeable--exhaustion. A suitable analogy might be constantly gunning and red-lining one’s old, inefficient engine. So I cut back to a half dose every other day. Much better. I still feel energetic--and optimistic--but am not completely exhausted hours later after the initial burst of energy has waned. It would certainly seem logical that younger, healthy, and/or athletic folks already have sufficient amounts of NAD, so they probably wouldn't notice much if any improvement from supplementation with NR. However, old folks have NAD deficiency as a result of aging, and probably see a much greater benefit from supplementation with NR. which increases NAD. I am guessing that most of the folks reporting little or no benefit from NR are either younger & healthy and have plenty of NAD; or, perhaps are taking far more than they need, producing some sort of negative hormesis-like response; or are not taking complementary doses of resveratrol, or other pterostilbenes, which operate in tandem with NAD as a substrate to influence anti-aging sirtuins. An update: I am now 68 and still taking NR from various makers, who add various components along with NR (all Niagen based) and at various dosages.. The 250 mg. dose is now my standard, however, and I no longer have the exhaustion effect. I don't know why, but it is gone and I am feeling great. I always take resveratrol daily, and many other supplements as noted above. I am also considering the other NAD precursor which is starting to become available, nicotinamide mononucleotide, but the price has got to come down significantly and some major advantage over NR demonstrated. Another possible effect from taking the 250 mg. NR dose is noteworthy: my fasting blood sugar is now running in the 60's and 70's regularly, but I do not feel bad. I have been doing a form of intermittent fasting for some time, but even when I have a regular meal, a few hours later my fasting glucose is back in the 60's & 70's. I test it daily. This may in fact serve as a long-term indicator of the continued efficacy of NR. I have never had fasting glucose levels this low, before taking 250 mg. of NR daily.
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Reviewed in the United States on April 30, 2015 by Joan
Im 64, i took one capsule before breakfast and soon after i couldnt stay awake and slept for almost 2 hrs and then just lay there unable be fully awake enough to get up for another hour, a few hours later i started to feel very brief pains not in but near joint areas randomly around my body. Dont know what to make of all this, so far nothing i can call positive has happened, ive only taken the one capsule i wont be taking a second one today, ill have to decided about taking one again tomorrow. I can only give it 3 stars at this point till I learn more. I do like the new bottle though, the way you twist the top and the clear part opens up with a hole to let the capsules out, its a unique design.
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Reviewed in the United States on April 6, 2025 by Amazon Customer
Great product no stomach upset and feel great on this
Reviewed in the United States on July 15, 2025 by Colleen D. ORourke
I started this earlier in the week and the next day i had nausea and a terrible feeling. At first I didn’t associate it with this product. Then the next day i took it and felt dizzy and nausea again it would come and then go and come back. 4 days later I said to myself I have to see my doctor my son who is a medic took my blood pressure and checked my heart rate and said your vitals are normal but make an appointment with the doctor. I thought what have I eaten or introduced lately and realized the only thing was this product. Today I didn’t take it and i have no nausea or dizziness so I won’t take it anymore. Really hoped it was for me 🥺
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Reviewed in the United States on August 4, 2025 by E Haddock