Search  for anything...
Advil

Advil Targeted Relief Pain Relieving Cream, Up to 8 Hours of Powerful Relief of Minor Arthritis Pain, Joint Pain, Lower Back Pain and Muscle Pain - 2.3 oz

  • Based on 435 reviews
Condition: New
Checking for the best price...
$9.99 Why this price?
Save $1.00 was $10.99

Buy Now, Pay Later

As low as $2 / mo
  • – 4-month term
  • – No impact on credit to apply
  • – Instant approval decision
  • – Secure and straightforward checkout

Ready to go? Add this product to your cart and select a plan during checkout.

Payment plans are offered through our trusted finance partners Klarna, Affirm, Afterpay, Zip, Apple Pay, and Google Pay. No-credit-needed leasing options through Acima may also be available at checkout.

Learn more about financing & leasing here.

Selected Option

Free shipping on this product

Non-returnable due to Food safety reasons

View our full returns policy here.

Availability: In Stock.
Fulfilled by Amazon
Arrives Wednesday, Aug 5
Order within 8 hours and 26 minutes
Available payment plans shown during checkout
Protection Plan Protect Your Purchase
Checking for protection plans...

Recently Viewed

Size: 2.3 Ounce


Features

  • One 2.3 oz Tube of Advil Targeted Relief Pain Relieving Cream - The only topical pain reliever with 4 powerful pain-fighting ingredients (1)
  • Provides a warming & cooling sensation on contact and lasts up to 8 hours (1)
  • Designed to quickly tackle pain four ways: targets, penetrates, blocks, and relieves
  • Fast and powerful relief for minor arthritis pain, muscle, joint and back pain - the perfect addition to your college dorm room essentials
  • Doesn't leave your skin feeling dry or greasy and easily glides onto skin, ensuring comfort with every use
  • Provides both cooling and warming sensations to enhance the pain relief experience
  • Topical pain relief without needing a prescription
  • HSA and FSA eligible item. Medicare Advantage OTC (MAOTC) eligible. *OTC benefits and eligible products vary by plan. Check your plan for specific details.

Description

Advil Targeted Relief Pain Relieving Cream – Your Fast-Acting Solution for Tough Pain! Designed to quickly tackle pain four ways: targets, penetrates, blocks, and relieves. This innovative formula delivers deep penetrating relief right where it hurts. Experience quick application and relief. Our powerful pain-fighting formula starts working on contact, delivering fast relief with a cooling plus a warming sensation that you can feel during application. Also, Targeted Relief doesn't leave your skin feeling dry or greasy, ensuring comfort with every use. This cream is your go-to for deep, penetrating relief that directly targets pain at the source. Its unique formula penetrates to the nerves, working on signaling pathways receptors to provide pain relief. No prescription required. Get back to doing what you love, without the burden of pain. Get ready to head back to college with confidence and stock up ensuring you're ready for anything the academic year throws your way. Choose Advil Targeted Relief Pain Relieving Cream – your ultimate companion for fast, effective pain relief right where you need it most. (1) Among the leading pain relief brands.

Product Dimensions ‏ : ‎ 1.7 x 2.6 x 5.9 inches; 3.18 ounces


Item model number ‏ : ‎ 73


Date First Available ‏ : ‎ February 2, 2024


Manufacturer ‏ : ‎ Haleon US Services Inc.


Best Sellers Rank: #3,048 in Health & Household (See Top 100 in Health & Household) #8 in Joint & Muscle Pain Relief Rubs


#8 in Joint & Muscle Pain Relief Rubs:


Customer Reviews: 4.3 4.3 out of 5 stars (4,701)


Brand Name: Advil


Product Benefits: Pain Relief


Specific Uses For Product: Muscle Pain


Active Ingredients: Camphor 3.1% - Topical analgesic Capsaicin 0.025% - Topical analgesic Menthol 10% - Topical analgesic Methyl salicylate 15% - Topical analgesic


Item Form: Cream


Age Range Description: Adult


Target Use Body Part: Head


Package Type Name: Tube


Model Number: 73


Dosage Form: Cream


Global Trade Identification Number: 42


Manufacturer: Haleon US Services Inc.


UPC: 305736555542


Item Weight: 3.18 Ounces


Item Dimensions: 1.7 x 2.6 x 5.9 inches


Number of Items: 1


Unit Count: 2.3 Ounce


Additional Features: Fast-Acting, Targeted


Frequently asked questions

If you place your order now, the estimated arrival date for this product is: Wednesday, Aug 5

This item is non-returnable:

Non-returnable due to Food safety reasons

View our full returns policy here.

  • Klarna Financing
  • Affirm Pay in 4
  • Affirm Financing
  • Afterpay Financing
  • Zip Pay in 4
  • Financing through Apple Pay
  • Financing through Google Pay
Leasing options through Acima may also be available during checkout.

Learn more about financing & leasing here.

Similar Products

Top Amazon Reviews

    • I smell like a granny and feel like a million!
Size: 4 Ounce
I highly recommend this for sciatic nerve pain due to piriformis syndrome. It helps at 100% where other helpful products only reach 50% at best. It's such a relief that I don't mind the smell at all. There are a lot of products available to help alleviate sciatic pain and sciatic pain from piriformis syndrome in particular. There are exercises that help and lifestyle changes that can address the underlying problem as well. I've tried just about everything available that you can purchase. I do the exercises. I'm making the lifestyle changes. Most of the products and exercises that are supposed to help do help to one extent or another , but even combining a variety of them has never been sufficient to handle a really intense stretch of pain coming from the piriformis syndrome. It hurts not only as a muscle site but all down my left leg. In the calf when it gets down to that area it's mostly on the outside and a bit towards the front and back. That area of pain feels a bit like a non-stop charlie horse at times, and at other times it feels like it's on fire almost. This morning the pain was so bad even having a copper leg brace on and the kind of brace that they sell that puts pressure on the points in the calf and having taken the ibuprofen and tylenol. I couldn't get the pain reduced to a point where I could have comfort at all and I was really miserable. I used one of my massage guns and that would just address the pain in one area and then the other areas would still hurt. I opened the Advil pain cream as soon as it was delivered. The cream has a light texture and it absorbs very quickly . My skin is on the dry side which might affect this but after I apply the cream my skin doesn't feel greasy or sticky. The smell is very strong and I think it's stronger than other kinds of rubs perhaps or maybe it just seems that way at the moment. It's not bad, it just has that muscle rub smell. Within minutes of applying the cream I noticed and Improvement. At first I thought maybe it was in my head but sure enough within 15 minutes the pain was reduced to where I could get up and walk to my kitchen and back within a tolerable level of pain. Within a half hour, now I'm just feeling a little pain at the very top of my left thigh in the back and it's not severe at all. I think I'm only noticing it because I'm actively considering how my leg feels for the purpose of this review. I also still feel some tightness, similar to when I do a deep stretch, in the area of my lower leg that not that long ago felt almost like it was having an endless charlie horse. It doesn't hurt. It's just some tightness in that area. And that's it! I didn't even use a super heavy application of the cream, and within half an hour anything going on with my leg wouldn't even be worth mentioning. Of course I still have to make lifestyle Changes in order for the pain to be fully resolved the majority of the days of the year but for flare-ups and plan to continue using this Advil pain cream. It's worth the trade off in having that muscle rub smell about my person. If it's having the pain completely shut me down so there's nothing I can really do VS. smelling like muscle rub, I'll take smelling like muscle rub. Another great thing I should probably add is that I have fairly sensitive skin and the Advil pain cream did not cause any irritation or rash. I highly recommend this pain cream from Advil ... show more
Reviewed in the United States on March 3, 2026 by Jenny Rabbit 1111
    • It works
Size: 4 Ounce
The good thing about it is that it does actually work. However, the smell is overwhelming. Don't put it on if you have to go out immediately. The pain does come back but for temporary relief it is very good.
Reviewed in the United States on April 3, 2026 by Customer Review
    • Amazing pain killing cream!!
Size: 4 Ounce
I have lower back spinal stenosis & have gotten pain patches to help with pain with the same ingredients from my acupuncturist, so thought I'd try this cream. Some days it really hurts to move but I know I need to keep moving. Well, this cream is a God send. I rub a quarter size in & in moments I can move w/o pain!!! I have gotten epidural corticosteroid shots every 4-5 months & after it wears off, this cream will be my lifesaver! Note: I bought a wand to rub it on my lower back so I didn't have residue on my hands. It is strong stuff, with a strong menthol smell but as a person with sensitive skin, I didn't get any irritation! And it's not sticky. Thank you Tylenol! ... show more
Reviewed in the United States on March 11, 2026 by KareeGirl
    • Best product on the market.
Size: 4 Ounce
This is a great product. It’s one of the few things that helps for my lower back - and i have a cabinet filled with them all: icy hot, biofreeze, lidocane patches etc. The ONLY reason this isn’t 5 stars is that it has a very strong menthol smell. It’s not something i could use if i was at work. At home i don’t care about the scent and I’m pain free. ... show more
Reviewed in the United States on December 2, 2025 by Debbie
    • Husband swears by this product
Size: 4 Ounce
My husband has shoulder issues that prevents him from sleeping thru the night. I Rub his shoulder each night with this product and he says it’s effective at dulling the pain and allowing him to sleep. It’s effective for him for at least 8 hours.
Reviewed in the United States on March 21, 2026 by GrannyB
    • Great at first then started burning next morning during exercise
Size: 4 Ounce
I’ve tried many popular pain creams with similar ingredients and never had any issues or reactions. I don’t have any allergies that I’m aware of. The Advil Targeted Relief Cream worked great at first when I put it on my knees, calves and lower back before going to bed in a cold room. It was nice and icy and on the stronger side relative to other pain creams, but the next morning while working out, the areas where I used the cream the night before started burning and the skin became irritated as my body began heating up from my workout. Any exposure to heat made it worse, I went into the dry sauna and my skin was burning to the point that I had to get out. Took a cold shower and used soap to try removing any residue of the cream from my skin but it only cooled down for a little bit until my body naturally warmed up a little later. The burning sensation returned, although more tolerable and mild than earlier in morning- and even felt cooling as well- as long as I stayed in a cool environment. This cream is very strong and intense and its residual effects do not “wear off” for many hours after its intended duration. I really liked this product at first and would have definitely continued using it for pain if it didn’t have this long lasting side-effect which seems to be triggered by heat. It has a strong mentholated smell which didn't bother me since I usually apply stronger creams like this at night before bed. If you plan to use this product, I strongly recommend staying away from any heat for at least the following 12 hours. If it didn’t have these side effects, I’d give it 5 stars. ... show more
Reviewed in the United States on May 16, 2024 by FYI
    • Works very well
Size: 2.3 Ounce
This works really well. I have recommended it to several friends. This is a good buy.
Reviewed in the United States on April 4, 2026 by jeanne r

Can't find a product?

Find it on Amazon first, then paste the link below.
Checking for best price...