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Advantage

Advantage XD Small Cat Flea Prevention & Treatment For Cats 1.8-9lbs. | 4-Topical Doses, 2-Months of Protection Per Dose

  • Based on 4,489 reviews
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  • – 6-month term
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Availability: In Stock.
Fulfilled by Amazon
Arrives Tuesday, Sep 8
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Style: Small Cat


Size: 4 Pack


Features

  • 8 months (4 doses) flea treatment and prevention for indoor and outdoor cats and kittens 1.8-9 lbs., 8 weeks or older
  • Longer-lasting protection vs. other topical products;* 2 months protection per dose, outlasting the typical flea life cycle *Based on label claims
  • Fast-acting treatment starts killing fleas within 30 minutes to 4 hours through contact
  • Easy-to-apply topical treatment, no prescription needed
  • Fragrance-free formula, containing a naturally derived ingredient Spinetoram - winner of a Green Chemistry award** **US EPA Presidential Green Chemistry Challenge. Designing Greener Chemicals Award. 2008.

Description

Cat lovers choose Advantage XD for double the lasting protection against fleas vs. other 1-month options. Advantage XD for small cats and kittens packs two full months of treatment and continuous protection in each dose, so your cat is protected for longer than the traditional 1-month formula. If your cat has already tousled with fleas, you’ll love that Advantage XD topical treatment starts killing fleas within 30 minutes to 4 hours through contact so they don’t have to bite and die. And with Advantage XD extended duration formula, that flea prevention remains effective for 8 weeks, outlasting the typical 6-week flea life cycle and preventing reinfestation.Find Advantage XD topical flea treatment available in a variety of pack sizes, from 2 months protection (1 dose), to 4 months protection (2 doses), or 8 months protection (4 doses). This fragrance-free formula contains Spinetoram, a naturally derived, Green Chemistry Award-winning ingredient.Advantage XD flea infestation prevention is effective on both indoor and outdoor cats. Your cat should be at least 8 weeks old and between 1.8 and 9 lbs. to use Advantage XD for small cats. Even with the squirmiest of kittens and cats, application is easy. This single, topical, spot-on application goes on the back of your cat’s neck at the base of the skull. You’ll simply place the tip of the tube on the skin and squeeze the tube to expel the entire contents directly on the skin. It's easier, there are no hard-to-swallow pills; this topical treatment goes on in seconds. See product label for more information.For the ultimate convenience in care, Advantage XD is available over the counter – no prescription needed. Once Advantage XD is applied, your cat is ready to get right back to exploring the outdoors or finding a cozy spot for a nap, while you get to enjoy peace of mind.Based on label claims US EPA Presidential Green Chemistry Challenge. Designing Greener Chemicals Award. 2008.

Brand: Advantage


Item Form: Topical


Scent: Unscented


Item Weight: 27.22 g


Active Ingredients: Spinetoram


Item Volume: 4 Milliliters


Allergen Information: Allergen-Free


Dog Breed Size: Small


Unit Count: 4 Count


Age Range (Description): 8 weeks and older


Product Dimensions ‏ : ‎ 4.75 x 4.25 x 0.88 inches; 0.96 ounces


Manufacturer recommended age ‏ : ‎ 1 month and up


Item model number ‏ : ‎ CA4241024AM


Date First Available ‏ : ‎ October 1, 2022


Manufacturer ‏ : ‎ Elanco US Inc


Best Sellers Rank: #2,324 in Pet Supplies (See Top 100 in Pet Supplies) #16 in Cat Flea Drops


#16 in Cat Flea Drops:


Customer Reviews: 4.4 4.4 out of 5 stars (4,489)


Brand Name: Advantage


Age Range Description: 8 weeks and older


UPC: 727804567507


Global Trade Identification Number: 07


Manufacturer Part Number: CA4241024AM


Model Number: CA4241024AM


Unit Count: 4 Count


Manufacturer: Elanco US Inc


Item Type Name: Topical


Item Form: Topical


Scent Name: Unscented


Dog Breed Size: Small


Target Species: Cat


Item Weight: 27.22 g


Volume: 4 Milliliters


Allergen Information: Allergen-Free


Active Ingredients: Spinetoram


Frequently asked questions

If you place your order now, the estimated arrival date for this product is: Tuesday, Sep 8

Yes, absolutely! You may return this product for a full refund within 30 days of receiving it.

To initiate a return, please visit our Returns Center.

View our full returns policy here.

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Similar Products

Top Amazon Reviews

    • Advantage XD Works - No Fleas! Advantage XD Works - No Fleas!
Style: Large Cat Size: 2 Pack
Review Image by E-PalmBeach
Review Image by E-PalmBeach
I recently rescued a male Siamese 10-month old kitten. I noticed that Jax had a few fleas and I did some research on safe, effective, flea control products. With warm year-round weather in Florida, fleas are known to thrive. Previously I have owned and loved dogs, and found out through trial and error that most over-the-counter flea products didn’t work. Trips to the vet for flea prescriptions became very expensive, so I set out to find something that worked. ... show more
Reviewed in the United States on June 13, 2026 Reviewed in the United States on June 13, 2026 by E-PalmBeach
    • The best for indoor cats
Style: Large Cat Size: 1 Pack
Works very well for indoor cats
Reviewed in the United States on June 8, 2026 by Gail Herold
    • The absolute best ive ever used !!! My girls are flea FREE !!! FREEDOM!!!
Style: Large Cat Size: 2 Pack
Definitely staying with with this flea prevention!! Let me give a big tip on how to do this Correctly!! 1st relax your cat one by one, brushing their hair whether they have short or medium or long. Just calmly gently as brushing, quietly split the section on the neck but keep dry. Dont get the section wet. If just slightly damp and I do mean SLIGHTLY, using either the mens old school comb to spread one side over then quietly the other side so not to bring attention 😉 ok? Then keeping them calm have your tube (ready and open) gently squeeze the tube with their meds smoothly throughout the open section. You don't have to rush or squeeze quick n run! Just stay calm. Squeeze upwards then the remaining back down just to be sure you got it all *meaning gently put onto their little opening.. 3 to 4 seconds Literally..Done!! ✔ they'll be curiously surprised 😆 🤣 then give them a treat .. want my advice? Ask away !! Kitty mama on the way 😍 💕 next month ill make a video showing exactly how simple this really is.. Tata 💋 ... show more
Reviewed in the United States on June 14, 2026 by Candy
    • Effective Flea Protection, But One Packaging Issue
Style: Small Cat Size: 1 Pack
Here's a positive review that also mentions the issue you experienced: ⭐⭐⭐⭐☆ Effective Flea Protection, But One Packaging Issue I've purchased Advantage XD Small Cat Flea Prevention several times for my cat, and overall I've been very happy with the product. It's easy to apply, provides long-lasting protection, and gives me peace of mind knowing my cat is protected from fleas for up to two months with a single dose. In my experience, the treatment has been effective and much more convenient than having to remember monthly applications. My cat tolerates it well, and I've continued to return to this product because of the results. The only reason I'm not giving it a full five stars is because my most recent purchase arrived with an empty Advantage box. The packaging and instructions were included, but the actual product was missing. It was disappointing, especially since I've had positive experiences with previous orders. Despite that issue, I still believe this is a quality flea treatment and will likely continue using it. I just hope the packaging and quality control issues are addressed going forward. ... show more
Reviewed in the United States on June 19, 2026 by Valerie
    • So far so good
Style: Small Cat Size: 4 Pack
FINALLY, my kittens and I have relief!! My new kittens came with unwanted guests but they were too young for the products I saw. I used a flea comb and baths with no real relief. Things got worse. I had my house and garage (where they're staying due to tenants allergies) fumigated before the fleas took hold of my house like they had the garage. I gave them both capstar while we waited. That evening I applied Frontline plus. They were still scratching. I gave another dose of capstar two days later hoping that they would finally be rid of all stages of fleas. NOPE. I gave the third dose. NOPE. Capstar works great but it only works on adult fleas for a short time. Frontline was useless. I finally applied advantage xd and finally we all have relief. No more incessant scratching. I truly hope it lasts. My kittens and I are so very grateful. I absolutely recommend this product. Don't waste money on Frontline plus. FYI, the tubes doesn't have a cap. The tops look like caps to be removed but it's the tip of the applicator. Just twist the top slightly and it's open. Nothing has to be removed. I needed YouTube to figure that out. ... show more
Reviewed in the United States on August 18, 2023 by Tanya Pearson
    • easy and it works
Style: Small Cat Size: 1 Pack
The day before the hurricane, we were rescued a mother, and two of her three babies sadly, we could not get the third she stayed hidden under a trailer. No one could seem to catch her, especially without hurting her. We were sick about it because it was quite a storm. Bittersweet we got her two days later, but she only lived two weeks. I don’t know besides being runt might’ve been going on. she took to me right away and the whole time here except to go potty she was sleep on my neck cuddled me. She ate well, but never gained weight because of the storm. There were no vets to get to right away. I don’t know if she had a seizure or what but we lost her anyway, this is about the product. I couldn’t put it on the babies. They were too small, but I put it on and what’s great is. It’s good for two months. That evening she had stopped scratching and running a flea come through. Her did not produce very much I am about to order another pack, it was also safe for her because often on they still nurse I did buy the three pack of the regular as well for the three kittens at the time. The surviving to are little chunky monkeys Free of fleas, I have another pack coming for them also. i’d love to use the one on mama on all of them, but it’s just not affordable right now we inherited a small colony of cats besides our hurricane babies Please everyone if you only have a couple of cats please get them fixed. You don’t realize how fast they pop them out most of the time they are inbred You are lucky if they live two weeks. The majority of the time the mothers will reject them almost immediately. They know the babies have problems so they tend to address the healthier. It’s a bit like triage for people you try to save the healthiest that will survive. look around there are places with low cost fees. We only have one. It’s hard to get appointments, but it’s only $35. You are going to pay a lot more than that and cat food and talk about MEDICAL. If you love animals stop them from breeding kittens are grown by about six weeks of age and become little teenagers, I love them all but for people that want kittens you don’t keep them that long and stop the madness ... show more
Reviewed in the United States on August 28, 2024 by Dawn
    • Not happy, ruined my kittens fur.
Style: Small Cat Size: 1 Pack
Advantage XD I’m am not happy with. I will not put it on my kitten again. She is 8 months old, 6-7 pounds and it made her fur sticky and hard clumps/mats at application site. I applied it directly to her skin as instructed and of course it has to spread as all the topical products do, but it’s not an oily feel on the fur when it disperses, it’s made her fur very clumpy and sticky. It made mats in her fur at the site. I tried to wet her fur down, wipe it off with a wash cloth and a baby wipe and tried brushing her, but it’s pulling and hurting her to do so. It’s like a thin layer of dried syrup on that spot of her head/neck. When I brushed her, so much fur came out of that area I worried she was going to have an allergic skin reaction like a few of the reviews said, luckily skin irritation hasn’t happened. I really am dissatisfied with the product. I have used Advantage II on my previous cats and never have had this happen. The fur on the application site would get a little oily, but not dry like this. I figured I would try the XD since it’s every other month, but this changed my mind so I will not be using it again. Her silky fur is so gross to the touch right now in that area, I am so sad and disappointed. It may be doing its job with the fleas, I really don’t know cause I wanted to use it as a precaution on her. She is strictly indoor but we have a dog (which takes a flea preventative) that goes outside and could bring one in and we don’t want one to move over to her and infest her. After the 2 months are up and she is due for another treatment, I will be looking for a different product. Thankfully I only bought one dose of this stuff. ... show more
Reviewed in the United States on March 1, 2025 by loveamazonshopping
    • Worked
Style: Large Cat Size: 2 Pack
Did the job.
Reviewed in the United States on June 22, 2026 by The Dude

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