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Amazon Basics Flea and Tick Topical Treatment and Prevention for Large Dogs (45-88 lbs), Fast Acting and Long Lasting, 3 Count, Packaging May Vary

  • Based on 14,071 reviews
Condition: New
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Availability: In Stock.
Fulfilled by Amazon

Arrives Sunday, Aug 2
Order within 13 hours and 32 minutes
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Size: 3 Count


Features

  • FAST-ACTING FORMULA: Starts eliminating fleas and ticks within 24 hours of treatment
  • COMPLETE PROTECTION: Active ingredients Fipronil and (s)-methoprene prevent flea infestations by killing flea eggs, flea larvae, biting flies and chewing lice
  • LONG-LASTING COVERAGE: One application provides up to 30 days of protection against pests, including deer ticks that may transmit Lyme disease
  • WATERPROOF FORMULA: 24 hours after application your pet's treatment is protected against rain and water activities
  • PACKAGING MAY VARY: Packaging may be different than what is shown but item and quality remain the same
  • Keep out of reach of children

Description

The Amazon Basics Flea and Tick Treatment for Large Dogs is comprehensive pest control and prevention designed for dogs weighing between 45-88 pounds. This flea and tick treatment for dogs starts working within 24 hours to tackle flea and tick infestations. Formulated with active ingredients Fipronil and (s)-methoprene to target flea eggs, flea larvae, biting flies, and chewing lice, the treatment breaks the flea life cycle and eliminates ticks, including those that may carry Lyme disease. This fast-acting, long-lasting treatment for dogs offers up to 30 days of continuous protection. Quality products for happy pets. Keep out of reach of children.

Item Form: Drops


Scent: Unscented


Item Weight: 22.68 g


Active Ingredients: Fipronil, Fipronil and (s)-Methoprene, Methoprene


Item Volume: 0.27 Fluid Ounces


Unit Count: 3 Count


Age Range (Description): 8 Weeks or Older


UPC:


Product Dimensions ‏ : ‎ 0.75 x 5.75 x 4.38 inches; 0.8 ounces


Item model number ‏ : ‎ 11287


Date First Available ‏ : ‎ November 13, 2019


Best Sellers Rank: #385 in Our Brands (See Top 100 in Our Brands) #8 in Dog Flea Drops


#8 in Dog Flea Drops:


Customer Reviews: 4.0 4.0 out of 5 stars (14,071)


Age Range Description: 8 Weeks or Older


UPC: 195515005722


Manufacturer Part Number: 11287


Model Number: 11287


Unit Count: 3 Count


Included Components: Three (3) 0.091 fl. oz. waterproof topical applications for dog flea and tick control.


Item Form: Drops


Scent Name: Unscented


Target Species: Dog


Item Weight: 22.68 g


Volume: 0.27 Fluid Ounces


Active Ingredients: Fipronil, Fipronil and (s)-Methoprene, Methoprene


Frequently asked questions

If you place your order now, the estimated arrival date for this product is: Sunday, Aug 2

Yes, absolutely! You may return this product for a full refund within 30 days of receiving it.

To initiate a return, please visit our Returns Center.

View our full returns policy here.

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Top Amazon Reviews


  • great medication - read the directions and do research!
Size: 6 Count
this flea medication works! a few things to note that i’ve seen in the reviews and it doesn’t seem like people do too much research - not to be abrasive but don’t miss out on a good product because people don’t read. this product is easy to use, effective, and provides protection from all life stages of fleas when used continuously. 1. your dog is still itching after you apply the medication because they have flea bites. they will continue to itch for a few days or weeks until the bites are gone. you can use a oatmeal or anti itch shampoo to help. itching doesn’t necessarily mean continuing biting. 2. you need to get it on to their skin and follow the directions which includes continuing in a line down their back from collar to beginning of tail. 3. if you have an active infestation you should couple this product with a oral medication. it is safe to mix most oral and topical preventatives/treatments. you also need to wash their bedding and vacuum. you can treat these items with diatomaceous earth - put it on bedding or carpet and then vacuum it up. if you don’t feel like doing this just throw the stuff away. you also need to empty your vacuum canister in a bag and take it to the garbage for best results. you should also bathe your dog, it is acceptable to do this with dawn dish soap which is especially effective for fleas. 4. fleas have a life cycle so if you are struggling with an infestation you probably need to repeat the above directions in #3 every week for about 6 weeks in order to kill the fleas. you should readminister an oral medication once a week as well that kills adult fleas. 5. yes dogs die from preventative flea medication. they also die from tapeworms that they get from fleas and fleas are miserable and pesky. it is a cost benefit analysis. dogs die from all sorts of flea medication, generic, oral, topical, or collars. it is a possibility that is listed in the information on this preventative - people don’t think it’ll be their dog. one of my dogs gets seizures from oral flea medication which is why we practice prevention from everyone else in the house and we have her on topical only. 6. this is a generic version of a brand name product. it is the same dosage and ingredients as frontline. the big makers of pet medications have spent billions of dollars in advertising and litigation to make generic pet medications difficult to find and utilize. this is worth a try and it’s a great value for the price. ... show more
Reviewed in the United States on September 1, 2025 by Ana Marie Broden

  • Works great! No fleas or ticks this year yet
Size: 6 Count
Working as it should! We live in the middle of the woods and haven’t had a problem this year yet. Trust this brand. Good quality and price. Doesn’t leave any greasiness or irritation to dogs. Both are German shepherds, one long hair and one short.
Reviewed in the United States on July 5, 2026 by Elisabeth Weaver

  • Chemically burned out girl! Horrible secondary bacterial infection Chemically burned out girl! Horrible secondary bacterial infection
Size: 3 Count
I am extremely disappointed and we are going through it over her!!! due to this product, our dog was chemically burned, she is a Shepard so thick coat under coat not easily visible and stopped eating and drinking after we administered this treatment, which she had had in the past with no issues at all. I thought she was upset with us for having given her treatment as she can be short dramatic, I noticed something wasn't right when she started licking at this spot by turning her body abnormally, her skin was crawling as it was burning her when we got a closer look at her skin, we immediately put her into warm water bath and rinsed her off to stop the chemical from staying on her, she developed a secondary bacterial infection from the chemical burns being so bad we have been traumatized fir her by this. We do not understand what happened and why she's used this before with no reactions, this is extremely concerning to us, she is so much pain her entire upper neck shoulder blade area is just like this as well. Her skin and hair is falling out and off scabbing and then all her hair fell out and exposed more to flesh, shes got an in infection so it's a horrible smell, we are and have been so so worried about her and she is still struggling. We have spent so much on this, and for this to even have happened is unacceptable. A allergic reaction is one thing that was not what this was, she's had many flea treatments in the last and never ever have we went through anything of the sorts, she's even had this one! So needless to say when we realized it was burning her skin off we had a major what the heck moment, this is horrible for her and all of us, we thought we were going to lose her she is still fighting a bad bad infection and the pain is terrible her tounge was burned from having licked it which is something we usually keep her from doing but she did it at night the first evening overnight unbeknownst to us she was not tripping out from the fleas dieing off she was suffering, this has broken our hearts we are continuing to work day in and day out to keep it covered with a light layer so she doesn't lick she is on antibiotics, her hair is still falling out in giant clumps when warm water rinsed and it's traumatized all of us. Out poor dog, I don't know why this happened but we are extremely upset it did, knowing it should not have happened and didn't before this had been very hard on us for her. We just don't want another animal to suffer the way our girl did and still is. It's been two weeks and we are still fighting to keep her well. Someone please if possible reach out to us and make this right in some way if there is even a way to really right this. Our dog could still not make it and if something is wrong with the product it needs pulled from shelfs, this is the worst thing I've ever went through, and it's not acceptable. Would love a customer service representative or someone for the product management team to reach us as soon as possible. We are really struggling here. ... show more
Reviewed in the United States on May 30, 2026 Reviewed in the United States on May 30, 2026 by sarra caroussos

  • Good in a Pinch, But Not a Long-Term Solution
Size: 3 Count
I needed flea treatment fast, and this did the job. It’s affordable, works well, and was a great value for something I needed immediately. That said, for long-term use, I’d recommend looking into something less toxic for your pup’s health. It’s a solid option if you’re in a bind, and it controlled our flea outbreak before it got out of hand, but if you have time to plan, I’d invest in a gentler product for your furry friend. ... show more
Reviewed in the United States on January 12, 2025 by Marissa

  • Great product. Keeps my pug sane.
Size: 3 Count
This works fantastic. I have been using it on my dogs for two years now during heavy tick and flea season. My pug likes to cross the street to the commercial kennels and chicken ranch. Untreated he can be swarming with fleas and keeps us awake with scratching. They drive him crazy and I get the occasional bite. I have a 27 pound pug and I use a full big dog tube. Within two days the fleas are gone and he stops scratching. After about 6 weeks we see a small amount of flea return. Also gets the ticks off of him. ... show more
Reviewed in the United States on June 27, 2026 by R. P. RIBEYRE

  • On the fence….
Size: 6 Count
Only used one dose but not sure it’s working very well.
Reviewed in the United States on June 13, 2026 by Tracy

  • Cheaper Than Name Brand, Comparable Quality
Size: 6 Count
It seems to work just as well as name brand for a fraction of the cost. I’ve never found a flea or tick on either of my dogs since I switched to this brand. I used to use advantix which was like 4x the price it does the same thing.
Reviewed in the United States on June 19, 2026 by Mountainmanbrewing

  • Works great.
Size: 6 Count
I have been using this Amazon brand for two years now and it works very well. I have two small and one very large dog. Has worked well on all of them.
Reviewed in the United States on July 2, 2026 by PB in SC

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