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THORNE

THORNE PharmaGABA-250, 250 mg Gamma-Aminobutyric Acid (GABA), 60 Capsules | Supports Relaxation, Mental Focus & Restful Sleep*, Natural-Source GABA, Non-Habit-Forming, NSF Contents Certified

  • Based on 668 reviews
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Availability: Only 5 left in stock, order soon!
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Arrives Tuesday, Sep 22
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Features

  • Natural Source: GABA is an important brain chemical that acts like a brake during times of runaway stress*
  • Calm: Promotes a calm, relaxed, focused state of mind*
  • Sleep: Supports restful sleep*
  • 3rd Party Contents Certified: This product has been third-party tested and certified to verify what's in the package matches what's on the label
  • Trusted: Thorne is trusted by 100+ professional sports teams and the #1 most recommended clinical brand by consumers and health-care practitioners (Based on a 2026 independent survey of US supplement consumers and health-care practitioners)

Description

PharmaGABA-250 Basic Nutrients Creatine Magnesium Glycinate Super EPA Berberine Magnesium Bisglycinate What makes Thorne supplements high quality? Thorne produces high-quality supplements through rigorous testing, well-researched ingredient sourcing, and strict manufacturing standards. We avoid unnecessary additives, binders, and fillers that may interfere with nutrient absorption. How does Thorne test its supplements for quality? To confirm the purity of our ingredients, the potency of our formulas, and the absence of all contaminants, we carry out a minimum of four rounds of testing on every product we manufacture. 100+ Thorne employees are dedicated to ensuring quality. Are Thorne supplements clinically tested and safe? Thorne partners with researchers and conducts clinical trials to support the efficacy of our products. Our team of doctors and medical experts substantiate each ingredient in every formula based on extensive clinical research and medical literature. Why are Thorne products more expensive than other supplements? When it comes to the health of our customers, we never settle. Thorne products may be priced higher than some others because of our commitment to quality at every step. We don’t simply meet the standard in dietary supplements — we set the standard. Where are Thorne supplements made and where are the ingredients sourced from? Located in South Carolina, Thorne manufactures supplements in the USA using globally sourced ingredients. When it comes to ingredient sourcing, we seek out only the highest-quality ingredients, selecting each one for its purity and effectiveness.

Product Dimensions ‏ : ‎ 2.09 x 2.09 x 3.72 inches; 2.4 ounces


Item model number ‏ : ‎ SP662-R


Date First Available ‏ : ‎ January 1, 2011


Manufacturer ‏ : ‎ Thorne Research


Best Sellers Rank: #20,553 in Health & Household (See Top 100 in Health & Household) #553 in Blended Vitamin & Mineral Supplements #1,916 in Diet & Sports Nutrition


#553 in Blended Vitamin & Mineral Supplements:


#1,916 in Diet & Sports Nutrition:


Customer Reviews: 4.6 4.6 out of 5 stars (668)


Brand Name: THORNE


Primary Supplement Type: natural GABA


Item Form: Capsule


Product Benefits: Sleep Support


Age Range Description: Adult


Container Type: Bottle


Dosage Form: Capsule


Model Name: Thorne Research


UPC: 693749662013


Manufacturer: Thorne Research


Global Trade Identification Number: 13


Model Number: SP662-R


Manufacturer Part Number: SP662-R


Unit Count: 60 Count


Item Weight: 2.4 ounces


Item Dimensions: 2.09 x 2.09 x 3.72 inches


Number of Items: 1


Total Servings Per Container: 60


Flavor: natural


Material Features: Vegetarian


Allergen Information: Dairy Free, Egg Free, Fish Free, Peanut Free, Shellfish Free, Soy Free, Tree Nut Free


Frequently asked questions

If you place your order now, the estimated arrival date for this product is: Tuesday, Sep 22

This item is non-returnable:

Non-returnable due to Food safety reasons

View our full returns policy here.

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Top Amazon Reviews

    • Excellent
Excellent, helps my pain a lot
Reviewed in the United States on July 28, 2026 by Christie Teem
    • worth it
this supplement really should be looked into for health. not sure why western docs aren't familar with this. this product does work. have bought from this vendor several times
Reviewed in the United States on May 11, 2026 by Bobbie Westbrook
    • Found something that finally works
My physician recommended this for my anxiety. I had tried many other supplements on my own that all promised to calm, relax, help focus, help sleep, etc. I have struggled with insomnia, anxiety and panic attacks for the past 4 years. I am currently taking Xanax to help manage my symptoms but I do not want to stay on Xanax the rest of my life. This is the only product that I have found that actually works. It keeps the anxiety from getting out of control. I can usually just breathe through it now. And this supplement has allowed me to start dosing back on Xanax. I take PharmaGaba 3 times daily as recommended. It does not make me sleepy but rather just levels everything out. It does not feel like I took a Xanax which you definitely feel the affects of but rather I noticed that I just felt calm throughout the day. No ups and downs, no jitters, no racing heart, no fight or flight feeling. It really has given me hope that I will be able to get off of Xanax and start to manage my anxiety in a healthier way. ... show more
Reviewed in the United States on June 14, 2022 by yogachic
    • Sleep great
Sleep Great
Reviewed in the United States on May 9, 2026 by Jill P
    • Stress reducer
This helps with brain firing it relaxes you but not in the sleepy sense. I usually take one to two before I go to bed or two in the morning before I start my day. It makes me feel less stressed.
Reviewed in the United States on November 12, 2024 by Designer Girl
    • great for upside down cortisol levels + need to sleep at night
I did a sleep/stress test and learned that my cortisol was upside down. Low in the morning - so sluggish and can't get out of bed, even at 10 AM, I could only get up because I HAD TO. High in the evening - laying in bed, almost like I have a panic attack - so alert, I can't sleep. I'm taking a few supplements now and altering my diet and lifestyle to reduce my cortisol levels. I want them high in the morning, so I can spring out of bed and low in the evening to lay down and rest. This PharmaGABA-250 is one of the supplements I started taking with the guidance of a functional nutritionist after we saw my cortisol labs. I can report that I noticed the effect of this supplement. I took it with a small glass of water about 30 minutes before bedtime. Fifteen minutes in, I started to feel very heavy - like how I feel when I'm sleepy. I did my bedtime routine - put on PJs, washed my face, brushed my teeth, etc., and got into bed. I woke up the next day a few minutes BEFORE my alarm. I felt refreshed, perfect. I've been taking this every night and have had great success, except one night when I had some sugar close to bedtime (I had cocoa), that disrupted the experience. So, GABA helps a lot, but diet also impacts me. One dose-related caution I would use is that my partner wanted to try this supplement to help him sleep when stressed about work. He couldn't stop thinking about work. He took one pill (same as I do), and he slept. He felt very heavy the next day and struggled with work in the morning, which was the exact opposite effect he wanted. He might benefit from Thorne's lower (100mg) dose. We've ordered it, but he hasn't tried it yet. If you're not sure how much you need, I recommend starting with the lower dose because you can always take more of them if you find you need them. ... show more
Reviewed in the United States on July 13, 2022 by McJeeee
    • Excellent quality product that works for me!
This is my first time purchasing this dosage; pricey but cheaper than taking 2 at the lower dose. First of all, I use muscle testing to figure out what I need, how much and what brand would be best for me. Out of lots of options on Amazon, this brand has consistently tested as the best option and I have used them for various things for a couple of years. So I definitely trust their quality. I can’t compare them in any other way or give evidence, only consistent experience and what I have seen with muscle testing. The interesting part of that is that I have gone into health food stores before and muscle tested options and nothing has tested strong. And I had to look at Amazon to find something. That says a lot to me. Plus Amazon usually tends to have better prices generally than health food stores. With Prime and considering gas and time, Amazon is usually the better option if it isn’t an emergency. I have been using this for stress and anxiety issues and take it in the morning. I know others who take it at night to help with sleep. It has definitely helped. My daughter has also been taking it and feels like it really makes a difference for her as well. I also have recommended this to friends. Wish I had known about it sooner! ... show more
Reviewed in the United States on September 20, 2019 by Shannon
    • Excellent quality supplement !
Third party tested
Reviewed in the United States on April 13, 2026 by Angela

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