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Systane Lubricant Eye Gel, Nighttime, 0.35-Ounces (package may vary)

  • Based on 6,113 reviews
Condition: New
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Availability: In Stock.
Fulfilled by Amazon

Arrives Wednesday, Dec 10
Order within 4 hours and 31 minutes
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Size: 0.35 Ounce (Pack of 1)


Features

  • Dr Recommended Brand of Artificial Tears
  • Thickest gel formulation to coat the eye with a strong layer of dry eye symptom protection.
  • Provides long-lasting, nighttime protection while you sleep.
  • For the temporary relief of burning and irritation due to dryness of the eye

Description

Systane Lubricant Eye Gel is designed to provide long-lasting, nighttime protection from dry eye symptoms while you sleep. Systane offers the thickest gel formulation to coat the eye with a strong layer of dry eye symptom protection. This strong layer of protection provides relief from even the severest symptoms of dry eye. Dry eye symptoms don’t have to keep you up at night, the nighttime protection works while you sleep, helping you get a good night’s rest. The Systane Family of Products is the 1 Doctor Recommended brand of artificial tears for dry eye symptom relief. Don’t let dry eyes ruin your day, Systane provides temporary relief from your symptoms.

Brand: Systane


Scent: Unscented


Item Form: Gel


Allergen Information: Allergen-Free


Material Feature: Fragrance Free


Is Discontinued By Manufacturer ‏ : ‎ No


Product Dimensions ‏ : ‎ 1.25 x 1.25 x 3.75 inches; 0.32 ounces


Item model number ‏ : ‎ 65047401


Date First Available ‏ : ‎ April 12, 2013


Manufacturer ‏ : ‎ Systane


Best Sellers Rank: #4,120 in Health & Household (See Top 100 in Health & Household) #15 in Dry Eye Relief Products #103 in Vision Products #556 in Sales & Deals


#15 in Dry Eye Relief Products:


#103 in Vision Products:


#556 in Sales & Deals:


Frequently asked questions

If you place your order now, the estimated arrival date for this product is: Wednesday, Dec 10

Yes, absolutely! You may return this product for a full refund within 30 days of receiving it.

To initiate a return, please visit our Returns Center.

View our full returns policy here.

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Top Amazon Reviews


  • Excellent Nighttime Relief – Truly Soothes the Entire Eye!
Size: 0.35 Ounce (Pack of 1)
Systane Lubricant Eye Gel is absolutely wonderful, especially for nighttime use. I’ve tried many eye drops over the years, but this gel stands out for its ability to coat and protect the top of the eyeball — exactly where regular drops often don’t reach or last. It provides deep, lasting moisture that stays in place throughout the night, leaving my eyes feeling refreshed and comfortable in the morning. Especially when you "stare" at a screen ALL DAY long. The texture is thick enough to truly protect but not so heavy that it feels uncomfortable. My personal opinion, if you struggle with dryness, especially on the surface or top area of your eyes, this is a must-have. Highly recommend for anyone needing reliable, soothing overnight relief! ... show more
Reviewed in the United States on October 8, 2025 by Prime User

  • Very Helpful for Dry Eyes
Size: 0.35 Ounce (Pack of 1)
I did not realize that when I am sleeping, my eyes come open just a little. That makes my eyes very dry. When I use this gel in each eye before bed, my eyes do not get dry during the night. This is NOT the same as Systane night time ointment. Only the gel helps me, and right now Amazon has the best price on it. ... show more
Reviewed in the United States on September 25, 2025 by MommaC

  • Terrific!
Size: 0.35 Ounce (Pack of 1)
This is great eye gel to use at bedtime. It feels so cool and refreshing when I put it in. All you need to do is squeeze a drop of two on the inner part of your eye, the part closest to your nose, then blink and few times, and the gel spreads over your entire eye. By the time you wake, your eyes are clear and refreshed. No hazy feeling until your eyes clear in the morning. This is especially great for people with dry eye or those who suffer eyestrain from having to work on a computer all day like I do. Even with a blue light filter on, our eyes are strained when it's dark, and winter is coming pretty fast now. The days are already getting shorter, meaning those of us who work at the computer in the evening will be subject to even more eyestrain than in the summer. Be aware, though, that this is a gel. You're going to be able to see after you put it in your eyes, but your vision will be very cloudy, so don't put it in until you're ready to lay down and go to sleep. This is a great eye gel to pair with one of the Systane brands for daytime. I've found this brand works best for me, and I stay with it. Great value for the money, too. A tube last quite a long time, even with nightly use. ... show more
Reviewed in the United States on August 12, 2024 by Coloratura Kiki

  • I haven't tried the gel yet
Size: 0.35 Ounce (Pack of 1)
I bought Systane drops, gel & ointment after betting samples from my opthalmogist. I use the drops during the day, I use the ointment at night & I'm almost out of ointment so I will try the gel next. This is the brand that my opthalmogist gave me, he's given to me 3 times so far, every time I go into the office. The drops are soothing, the ointment is really soothing & great for putting in at bedtime to keep my eye lubricated while sleeping, I use the drops during the day & since my dr gave me "PF=preservative free" this is what I buy. I'm almost out of the ointment, so I'll be using the gel, & give anothet review. Systane is a great product & if my dr recommends it then I'll use it. It cost a little more than other products but it's worth it. ... show more
Reviewed in the United States on June 13, 2024 by Bee

  • BUY IT! Best ANYWHERE
Size: Pack of 2
I suffer from severe dry eye disease. I also suffer from something called vascularization. When my eyes are dry, vascularization worsens and I lose my vision. Furthermore, when my eyes are dry, they look gray. I find that ointments exacerbate the problem. I’ve tried nighttime gels and the two best are genteel night gel and this one. If I begin to lose my vision during the day, I take out my special scleral lenses, put this in my eyes and take a nap. When I wake up, my vision is COMPLETELY restored and my eyes look a lot more vibrant and less irritated. . This does not happen with the genteel tho it’s better than nothing. Systane is, by FAR, the most superior product on the market and I can tell you that it WORKS. ... show more
Reviewed in the United States on August 8, 2025 by LMAB

  • Love this product!
Size: Pack of 2
I developed dry eye several years ago and started putting this gel in my eyes every night before bed. This product helps me sleep and provides great lubrication. It is pretty watery though and tends to seep out my eyes during the night so I wake up with it dried in my eyelashes, but I'll take that if it means I can sleep with no pain! ... show more
Reviewed in the United States on August 4, 2025 by Samantha Glenn

  • Why have they been out of stock?
Size: 0.35 Ounce (Pack of 1)
Has there been any communication as to when these drops will be back in stock? I haven’t been able to purchase them since Oct 2024. They work great in my eyes. I use them in my eyes before bedtime and it helps heal the dryness.
Reviewed in the United States on June 26, 2025 by Debbie

  • The best I've used
Size: 0.35 Ounce (Pack of 1)
This is the BEST night eye treatment I have used for major eye dryness. I was unable to get it for several months so am very pleased it has returned. ( even the Alcon website didn't have it in stock for quite a while) Better than gel drops or any ointment I have tried.
Reviewed in the United States on August 4, 2025 by Reba

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