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SkinMedica TNS Advanced+ Face Serum - Multi Peptide Serum to Help Improve the Appearance of Wrinkles, Fine Lines, Skin Tone & Texture (1 oz)

  • Based on 196 reviews
Condition: New
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Availability: In Stock.
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Arrives Tuesday, Oct 27
Order within 15 hours and 54 minutes
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Features

  • Next-Generation, Skin Rejuvenating Formula - A powerful peptide serum that helps target the appearance of fine lines, deep wrinkles and sagging skin. Enriched with TNS-MR, an advanced formula that acts on multiple levels to help get you to your age-defying results. Suitable for all skin types.
  • Key Ingredients - In this two chamber visibly firming serum, a next-generation growth factor blend helps to support healthy skin functions while an innovative peptide complex nourishes your skin. In the second chamber, Renessensce (RSC) Advanced is specifically designed to support the results of the growth factor blend, made up of a highly active blend of Marine Extract and Green Microalgae.
  • Key Benefits - Additional benefits of this growth factor serum include smoothing the appearance of coarse wrinkles and fine lines, as well as addressing sagging skin with visibile results in just 2 weeks.
  • Our Founding Story - Our founders began a revolution in skin health that continues to fuel the scientific research, innovation, and transformative results we're known for. Our approach to product innovation relies on research and bridging the gap between biological processes, revolutionary formulations, and clinical results.

Description

AHA/BHA Cleanser TNS Advanced+ Serum Even & Correct Treatment Hydra Collagen Hydrator Mineral SPF 35 Sunscreen

Product Dimensions ‏ : ‎ 2.41 x 1.63 x 7.63 inches; 7.68 ounces


Manufacturer ‏ : ‎ SkinMedica


Best Sellers Rank: #10,351 in Beauty & Personal Care (See Top 100 in Beauty & Personal Care) #261 in Facial Serums


#261 in Facial Serums:


Customer Reviews: 4.1 4.1 out of 5 stars (196)


Skin Type: All, Combination, Sensitive


Product Benefits: TNS Advanced+ Serum is a proven facial skincare product that smooths the appearance of wrinkles and fine lines, targets sagging, and rejuvenates skin


Target Use Body Part: Face


Scent Name: Aloe


Special Ingredients: Next-generation growth factor blend — supports healthy skin functions


Item Form: Serum


Brand Name: SkinMedica


Number of Items: 1


Global Trade Identification Number: 49


Manufacturer: SkinMedica


Item Weight: 7.68 ounces


Item Volume: 2.88 kg


Unit Count: 1 Fluid Ounces


Material Features: Natural


Active Ingredients: peptides


Recommended Uses For Product: Professional Skin Care


Frequently asked questions

If you place your order now, the estimated arrival date for this product is: Tuesday, Oct 27

Yes, absolutely! You may return this product for a full refund within 30 days of receiving it.

To initiate a return, please visit our Returns Center.

View our full returns policy here.

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Top Amazon Reviews


  • One of the Best Anti-Aging Serums Available — True Long-Term Investment in Your Skin
At 52 with post-menopausal dry, mature skin, I’ve tried an enormous range of anti-aging products — from luxury Korean skincare to dermatologist-dispensed growth factors, peptides, PDRN, and exosome formulas. Very few products earn a permanent place in my routine. SkinMedica TNS Advanced+ is one of them. This is not a trendy product. It’s not flashy. And it’s definitely not cheap. But after using it consistently, I understand exactly why this has become one of the most respected anti-aging serums on the market. First, it’s important to set expectations correctly. This is not a product that gives you dramatic overnight results. You’re not going to wake up looking ten years younger after one use. What this product does — and does exceptionally well — is act as a long-term insurance policy for aging skin. It improves overall skin quality, supports elasticity, and helps maintain healthier-looking skin over time. And that’s exactly why I keep coming back to it. The texture is unique but very well formulated. The dual-chamber pump dispenses two formulas that blend into a lightweight, silky serum that spreads easily and absorbs quickly. It layers beautifully with other skincare and never feels heavy or greasy — which is important for daily, long-term use. Over time, what I notice most is improved skin quality. My skin looks smoother, more refined, and more resilient. Fine lines appear softer, and my overall tone looks healthier and more balanced. It’s subtle, gradual improvement — but it’s real and consistent. I also use this alongside the SkinMedica neck and eye cream, and I find they work beautifully together as a comprehensive anti-aging routine. These products aren’t about quick fixes — they’re about aging better over time, and that’s exactly what they deliver. The scent is mild and fades quickly. It’s slightly clinical, which is typical for growth factor-based products, but it doesn’t linger and doesn’t bother me at all. Yes, this serum is expensive. There’s no way around that. However, it lasts a long time, and you don’t need much product per application. When I look at the performance, formulation, and long-term benefits, I see it as an investment rather than a splurge. I’ve tried many products that promise dramatic results, but very few that I trust for long-term skin health. This is one of those rare products that has earned a permanent place in my routine. If you’re serious about aging well rather than chasing quick fixes, this is one of the best products available. ... show more
Reviewed in the United States on March 28, 2026 by TheFaceLadyG

  • Expensive but I believe it’s worth it!
The best, but expensive!
Reviewed in the United States on August 4, 2026 by DWo

  • Defective pump
So disappointed. I'm sure this is a great product... if you can use it. The pump stopped working after less than 2 weeks from the time I received it. They offered several suggestions to fix it, but nothing worked. I was so looking forward to seeing the great results I was expecting from this product. It was expensive, and I dont usually put out that kind of money. So I splurged a bit because I was willing to pay for good results. Now I'm out nearly $300. I dont think it deserves even 1 star, but that's my lowest option. ... show more
Reviewed in the United States on March 24, 2026 by Cindy

  • BEST STUFF!!!
Love this stuff works exactly like their ad says!! …and the greatest thing is that you can see results quickly!! It’s pricey so I tried to stretch it out, but it does work!!
Reviewed in the United States on August 20, 2026 by ABSlidell

  • Skincare Game Changer
I have been using TNS for 4 weeks now. I use it twice a day and I am already seeing very good results. My lines around my mouth have significantly faded. I also have a large brown area due to medication. It has lightened a lot. Some of the darker spots are still noticeable, but I know you have to use this for a full 6 months to see the full results. Just after 4 weeks, the lighter brown spots are almost gone. I use on my face and neck. My neck is also less "turkey" like. I can't wait to see the full 6 months results if this is what I'm seeing after 1 month. I am a 50 year old female with dry skin. Highly recommend. ... show more
Reviewed in the United States on March 12, 2026 by Beth1025

  • Only lasts 6 weeks!
I received this April 29th and have used exactly as directed: 1 pump from each side twice daily. It ran out today June 11th. So, it lasted 6 weeks - NOT 3-4 months as advertised. I can’t justify the expense for how quickly it runs out.
Reviewed in the United States on June 12, 2026 by Double H

  • Great product, high price for small quantity
a good quality product, too expensive, lightweight, non-greasy, not enough product for the size of the container
Reviewed in the United States on June 15, 2026 by Happy Days

  • Too expensive
This works but the cost is unacceptable. Using once a day, container only lasts 4 months. That said. My skin looks great and I get compliments It does not help with sunspots. Going to try The Ordinary GF and compare.
Reviewed in the United States on May 12, 2026 by Discriminating Buyer

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