Differin Acne Treatment Gel, 60 Day Supply, Retinoid Treatment for Face with 0.1% Adapalene, Gentle Skin Care for Acne Prone Sensitive Skin, 15g Tube (Pack of 2) (Packaging May Vary)
Condition: New
Buy Now, Pay Later
As low as
$5
/ mo
Learn more
- – 4-month term
- – No impact on credit
- – Instant approval decision
- – Secure and straightforward checkout
Ready to go? Add this product to your cart and select a plan during checkout.
Payment plans are offered through our trusted finance partners Klarna, PayTomorrow, Affirm, Afterpay, Apple Pay, and PayPal. No-credit-needed leasing options through Acima may also be available at checkout.
Learn more about financing & leasing here.
Selected Option
Free shipping on this product
30-day returns
Learn more
FREE 30-day refund/replacement
To qualify for a full refund, items must be returned in their original, unused condition. If an item is returned in a used, damaged, or materially different state, you may be granted a partial refund.
To initiate a return, please visit our Returns Center.
View our full returns policy here.
Availability:
In Stock.
Arrives
Wednesday, Sep 24
Recently Viewed
Style: Tube
Size: 30g (60 Day Supply)
Features
- TARGETS ACNE: Clears breakouts where they start (Deep in pores) and prevents new acne from forming, which ultimately restores skin's texture and tone
- CLEARS, TREATS & PREVENTS: Differin works differently than other Acne treatments by normalizing skin cell turnover and effectively targets two primary causes of Acne, clogged pores and inflammation
- RX STRENGTH ACNE RETINOID: Adapalene was created for superior tolerability compared to other prescription retinoid products not containing Adapalene; It is suitable for use as part of your morning or evening regimen
- DERMATOLOGIST RECOMMENDED: Water based formula, oil free, alcohol free, fragrance free, non comedogenic; Helps reduce the risk of scarring and Hyperpigmentation by treating Acne
- REAL RESULTS: In a clinical study, Differin gel provided up to 87 percent reduction in acne breakouts after 12 weeks, which will continue to improve with further use
Description
Differin Gel Acne Treatment contains adapalene, an Rx-strength acne-fighting retinoid that helps clear breakouts where they start (works deep into pores in 5 minutes), helps prevents new acne from forming, and as a result, can restore skin's overall tone and texture. Adapalene is the first over-the-counter active ingredient for acne in more than 30 years. It clears acne with the power of an Rx without the prescription, prevents breakouts, blackheads, whiteheads, blemishes and clogged pores, and can be used to effectively treat acne, or maskne, caused by wearing face masks or facial coverings. When used as directed, you could start to see results in as little as 1 week, and when used every single day, Differin Gel can help reduce up to 87% of acne in just 12 weeks (Cunliffe et al 1998, Galderma Laboratories).
Item Form: Gel
Scent: Unscented
Brand: Differin
Product Benefits: Anti-Acne
Skin Type: Sensitive
Is Discontinued By Manufacturer : No
Product Dimensions : 4 x 5 x 7 inches; 1.06 ounces
Item model number : 0299.024060
Department : Beauty & Personal Care
UPC :
Manufacturer : Galderma
Best Sellers Rank: #153 in Beauty & Personal Care (See Top 100 in Beauty & Personal Care) #6 in Facial Masks
#6 in Facial Masks:
Customer Reviews: 4.4 4.4 out of 5 stars 69,079 ratings
Frequently asked questions
If you place your order now, the estimated arrival date for this product is:
Wednesday, Sep 24
Yes, absolutely! You may return this product for a full refund within 30 days of receiving it.
To initiate a return, please visit our Returns Center.
View our full returns policy here.
To initiate a return, please visit our Returns Center.
View our full returns policy here.
- Klarna Financing
- Affirm Pay in 4
- Affirm Financing
- Afterpay Financing
- PayTomorrow Financing
- Financing through Apple Pay
Learn more about financing & leasing here.
Similar Products
Top Amazon Reviews
I have been using Differin for over a year now (around 14 months giver or take) and did not publish a review until now. If you want an in-depth review, read on. For the tl;dr version: it works, just stick with it. Btw, I was not paid for this nor was I sent this product (although they should be sending it, given how many tubes I've bought). I had the MOST TERRIBLE acne. No, I'm not talking about a small tiny excuse of a blemish that your friend with great skin complains about when she has her "bad skin" days. My face was RED and PAINFUL. My cheeks were COVERED all the time, and I had no area on my face where acne wouldn't pop up. Nose, brows, chin, jaw, underneath the jaw, you name it. I had tried Curology and while my skin got amazing for the first 6 months, my acne returned with a VENGEANCE. I had tried so many things, clay masks, benzoyl peroxide, salicylic acid, other AHAs and BHAs, sulfur, rosehip oil, and even supplements like zinc and milk thistle, you name it. Nothing worked at all. I was so so embarrassed of my skin, but I couldn't wear makeup either since makeup made my acne SO MUCH worse. I heard about Differin and I figured "well, might as well give this a try cause it can't get any worse". Boy, I was wrong. It did get worse. Much worse. Suddenly I had SO much more acne and I felt like crap. I couldn't believe my skin could get worse, but it did. Differin was the only thing I was using so I knew this was it. I was depressed but I stuck with it, cause I wanted to test it for at least 4 months. I thought I might as well test the claim, since my skin is so bad already. The first month was really really bad. It brought all underlying acne to the surface i.e. the purge phase. It did the purging for 3-4 months, but the first month was THE WORST. Not gonna lie to you, that first month will probably be the worst skin you've had in your life. Your skin will become SO SENSITIVE! Anticipate that! My skin has never been sensitive to products but while using this, my regular moisturizers and masks would sting like crazy (get stuff with no fragrance/alcohol or acids!). It didn't affect my skin in any other way, it just stung a lot. Oh, and I used to get my upper lip and brows waxed. Not with this you can't, the wax will tear off your skin since it gets much more sensitive. I learned the hard way. ONLY do threading! However, after I waited out the terrible, terrible first month, I slowly began to see improvements. Marginal, though. I had acne, but I probably had just a tad less. And it continued that way, it kept improving. Eventually, my skin was so much clearer than before! I still had acne, mind you, it's not a miracle drug, but it was few and far in between. There would be times when I had no active acne, which was HUGE for me!! My face usually looked like a connect the dots game. However, I did hit a plateau. This worked phenomenally at reducing my ugly acne all over my face to a few zits here and there, however, my issue was deeper than that. Eventually, I went to a doctor and got on spironolactone. Now, I am both on my Spiro and this. The combo of these two have made my skin so clear! I could have never imagined this day! I still need to use this, I have noticed my Spiro is not enough to keep zits at bay and if I skip a couple of nights putting on differin, new zits come up. I am so much happier now that I don't have zillions of gross zits on my face. I still get zits if I eat sugar or near my period but man, I am a long way from before! I have a few blemishes left over from before but I honestly don't care, my skin looks wayyy better. I can hide my blemishes with a sheer foundation of spot concealing if I want. So if you've read till the end, the lesson is: be PATIENT and be realistic! Your acne did not appear overnight and will not disappear overnight. If you stick with this, it WILL work. However, your mileage may vary. My acne was extremely bad, so after I hit my "acne plateau" I went to the doctor. If your acne is not as bad, it's likely differin is all you need for clear skin! If you're on the fence, confused, depressed, frustrated and/or can't afford a doctor, it's worth a shot! Just be patient and gentle with your skin!
...
show more
Reviewed in the United States on June 9, 2018 by Biryani
Style: Tube
Size: 30 Day Supply
This really is a great product. I have repurchased several times. you get a great amount because you really don’t need to use a lot. It works great and as long as you are moisturizing good, it has not dried out my skin. Has been a staple in my routine and at this point i have no acne!
Reviewed in the United States on September 7, 2025 by lauren
If you don't read any further in my review, please know this: IT GETS A LOT WORSE before it GETS MUCH BETTER. HANG IN THERE. I'm posting this in hopes this helps someone. First, some history: I've struggled with moderate acne from my teenage to adult years. In my early and mid 30s, my acne has turned into painful cysts that predominantly cover my cheeks, jawline and neck. I also have breakouts on my shoulders, back and chest, though they aren't anything like my face. The areas I break out in would lead me to believe it's hormonal. Since I've also had hair loss and have had cysts on my ovaries, there was a thought it was PCOS, but dozens of blood tests and expensive doctor visits later, that was ruled out. I spend COUNTLESS, and I mean COUNTLESS hours researching about acne. It's ruined my self-esteem and confidence, I never feel attractive, and I even have trouble looking at people sometimes. My skin is PAINFUL due to the deep cysts and inflammation. So much so, some days I just wanted to cut my skin off. It's been hard not to pick, but of course even if I don't, my skin is left with red marks that are just has hard to cover up as the inflamed bumps. I've tried EVERYTHING over the years. You name it, I've tried it, and that includes Acutane (but I wouldn't stay on it due to concerns over liver damage). The only thing I haven't tried that I heard could work is Spirnolactane. I was actually prescribed it but decided not to take it, again, over concerns about what it would due to my health. I don't even know how many dermatologist, primary care and OB/GYN appts I've had to discuss the matter. One derm went so far as to tell me, "If you still have acne at this age, you'll always have acne." In other words, I'm hopeless. I hated that guy. That was told to me when I was around 22 and I've never forgotten it 13 years later. Recently, I moved to a new town and got a facial. The woman that was treating me suggested Differin Gel. She mentioned she'd seen some success with it and that it was a fairly new OTC product. I figured, what in the heck do I have to lose. Desperate, I ordered it from Amazon. And after using it for the first time, I BROKE OUT EVERYWHERE, particularly my forehead. It was AWFUL. My only patch of clear skin was now what seemed to be infinite whiteheads. Every pore was a whitehead. It was awwwwwful!!! I immediately quit the product, and was so angry that another thing failed me. It took WEEKS for the whitehead breakout to clear up. While I waited, I kept researching it. I don't know why. And I read how people talked about it "purging" the skin so people get a bad initial breakout. Ok. Well, I don't know if it was out of frustration or a little nagging gut feeling, I decided to try it again. AND MY SKIN GOT SO RED AND DRY AND BURNED SO BADLY. I mean, excruciatingly painful. And it turns out that's just because I was coating on a thick layer of it all over my skin. How embarrassing showing up for work and my whole face is just red and massive FLAKES. But after all that flaking and peeling, and using non-stop aloe on it (also borrowed my husband's thick Aveeno Eczema lotion... it seems to really work!), I had.... clear skin. I can't believe I'm typing this. It's been weeks, and my skin has cleared up 98% (I did have a couple neck and jawling cysts this period cycle, though - but they're not as hidden under the surface as they used to be). My skin doesn't get nearly as oily (overcompensating for the dryness of Differin) or as flaky (because I'm using a little bit for the whole face with a little more added onto my problem areas). It seems to have finally balanced out. I really just can't believe it, and I am so unbelievably happy and feeling so much more confident than I have in a long time. I truly hope this helps someone. Shoot me a question on here if you have one and I'll be happy to answer. For the record, after a ton of my own research, I believe I have a sensitivity to DHT. My blood test DHT levels are normal, but as I understand it, sensitivity to DHT cannot be measured, and I believe that may explain my female hair loss and cystic acne. I recently purchased Saw Palmetto Extract to see if that can help -- though it made me feel very faint so I stopped after a third day.
...
show more
Reviewed in the United States on March 29, 2018 by lkwilson06
Style: Tube
Size: 30g (60 Day Supply)
I have extremely sensitive thin skin. I saw some of the other reviews with some having little results or adverse reactions and was a little nervous about using this product. However, there were many with very good results so I tested on small area for the first week. I used small amount and within 4 days I could see it was working well. Moved on to spot treating all over face and it seems to be working well. No severe side affects so far. No redness, swelling or skin peeling. Very happy with results so far, but the box is huge compared to size of product inside. It's tiny, about the size of my finger.
...
show more
Reviewed in the United States on September 2, 2025 by Jeannie