Differin Acne Treatment Gel, 60 Day Supply, Retinoid Treatment for Face with 0.1% Adapalene, Gentle Skin Care for Acne Prone Sensitive Skin, 15g Tube (Pack of 2) (Packaging May Vary)
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Availability:
In Stock.
Arrives
Saturday, Aug 9
Style: Tube
Size: 30g (60 Day Supply)
Features
- TARGETS ACNE: Clears breakouts where they start (Deep in pores) and prevents new acne from forming, which ultimately restores skin's texture and tone
- CLEARS, TREATS & PREVENTS: Differin works differently than other Acne treatments by normalizing skin cell turnover and effectively targets two primary causes of Acne, clogged pores and inflammation
- RX STRENGTH ACNE RETINOID: Adapalene was created for superior tolerability compared to other prescription retinoid products not containing Adapalene; It is suitable for use as part of your morning or evening regimen
- DERMATOLOGIST RECOMMENDED: Water based formula, oil free, alcohol free, fragrance free, non comedogenic; Helps reduce the risk of scarring and Hyperpigmentation by treating Acne
- REAL RESULTS: In a clinical study, Differin gel provided up to 87 percent reduction in acne breakouts after 12 weeks, which will continue to improve with further use
Description
Differin Gel Acne Treatment contains adapalene, an Rx-strength acne-fighting retinoid that helps clear breakouts where they start (works deep into pores in 5 minutes), helps prevents new acne from forming, and as a result, can restore skin's overall tone and texture. Adapalene is the first over-the-counter active ingredient for acne in more than 30 years. It clears acne with the power of an Rx without the prescription, prevents breakouts, blackheads, whiteheads, blemishes and clogged pores, and can be used to effectively treat acne, or maskne, caused by wearing face masks or facial coverings. When used as directed, you could start to see results in as little as 1 week, and when used every single day, Differin Gel can help reduce up to 87% of acne in just 12 weeks (Cunliffe et al 1998, Galderma Laboratories).
Item Form: Gel
Scent: Unscented
Brand: Differin
Product Benefits: Anti-Acne
Skin Type: Sensitive
Is Discontinued By Manufacturer : No
Product Dimensions : 4 x 5 x 7 inches; 1.06 ounces
Item model number : 0299.024060
Department : Beauty & Personal Care
UPC :
Manufacturer : Galderma
Best Sellers Rank: #40 in Beauty & Personal Care (See Top 100 in Beauty & Personal Care) #5 in Facial Masks
#5 in Facial Masks:
Customer Reviews: 4.5 4.5 out of 5 stars 84,096 ratings
Frequently asked questions
If you place your order now, the estimated arrival date for this product is:
Saturday, Aug 9
Yes, absolutely! You may return this product for a full refund within 30 days of receiving it.
To initiate a return, please visit our Returns Center.
View our full returns policy here.
To initiate a return, please visit our Returns Center.
View our full returns policy here.
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Top Amazon Reviews
I have been using Differin for over a year now (around 14 months giver or take) and did not publish a review until now. If you want an in-depth review, read on. For the tl;dr version: it works, just stick with it. Btw, I was not paid for this nor was I sent this product (although they should be sending it, given how many tubes I've bought). I had the MOST TERRIBLE acne. No, I'm not talking about a small tiny excuse of a blemish that your friend with great skin complains about when she has her "bad skin" days. My face was RED and PAINFUL. My cheeks were COVERED all the time, and I had no area on my face where acne wouldn't pop up. Nose, brows, chin, jaw, underneath the jaw, you name it. I had tried Curology and while my skin got amazing for the first 6 months, my acne returned with a VENGEANCE. I had tried so many things, clay masks, benzoyl peroxide, salicylic acid, other AHAs and BHAs, sulfur, rosehip oil, and even supplements like zinc and milk thistle, you name it. Nothing worked at all. I was so so embarrassed of my skin, but I couldn't wear makeup either since makeup made my acne SO MUCH worse. I heard about Differin and I figured "well, might as well give this a try cause it can't get any worse". Boy, I was wrong. It did get worse. Much worse. Suddenly I had SO much more acne and I felt like crap. I couldn't believe my skin could get worse, but it did. Differin was the only thing I was using so I knew this was it. I was depressed but I stuck with it, cause I wanted to test it for at least 4 months. I thought I might as well test the claim, since my skin is so bad already. The first month was really really bad. It brought all underlying acne to the surface i.e. the purge phase. It did the purging for 3-4 months, but the first month was THE WORST. Not gonna lie to you, that first month will probably be the worst skin you've had in your life. Your skin will become SO SENSITIVE! Anticipate that! My skin has never been sensitive to products but while using this, my regular moisturizers and masks would sting like crazy (get stuff with no fragrance/alcohol or acids!). It didn't affect my skin in any other way, it just stung a lot. Oh, and I used to get my upper lip and brows waxed. Not with this you can't, the wax will tear off your skin since it gets much more sensitive. I learned the hard way. ONLY do threading! However, after I waited out the terrible, terrible first month, I slowly began to see improvements. Marginal, though. I had acne, but I probably had just a tad less. And it continued that way, it kept improving. Eventually, my skin was so much clearer than before! I still had acne, mind you, it's not a miracle drug, but it was few and far in between. There would be times when I had no active acne, which was HUGE for me!! My face usually looked like a connect the dots game. However, I did hit a plateau. This worked phenomenally at reducing my ugly acne all over my face to a few zits here and there, however, my issue was deeper than that. Eventually, I went to a doctor and got on spironolactone. Now, I am both on my Spiro and this. The combo of these two have made my skin so clear! I could have never imagined this day! I still need to use this, I have noticed my Spiro is not enough to keep zits at bay and if I skip a couple of nights putting on differin, new zits come up. I am so much happier now that I don't have zillions of gross zits on my face. I still get zits if I eat sugar or near my period but man, I am a long way from before! I have a few blemishes left over from before but I honestly don't care, my skin looks wayyy better. I can hide my blemishes with a sheer foundation of spot concealing if I want. So if you've read till the end, the lesson is: be PATIENT and be realistic! Your acne did not appear overnight and will not disappear overnight. If you stick with this, it WILL work. However, your mileage may vary. My acne was extremely bad, so after I hit my "acne plateau" I went to the doctor. If your acne is not as bad, it's likely differin is all you need for clear skin! If you're on the fence, confused, depressed, frustrated and/or can't afford a doctor, it's worth a shot! Just be patient and gentle with your skin!
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Reviewed in the United States on June 9, 2018 by Biryani
Style: Single-Dose Pump
Size: 45g (90 Day Supply)
I really like Defferin. Now that it’s over the counter, it’s game over. I have extremely sensitive skin, I can’t wear certain makeup or use certain brands because of how sensitive it is. I break out or get hives with this sensitivity. I also have combo skin, with acne mostly around my chin (hormonal) with occasional T zone pimples. I have been using this on my skin, with a moisturizer, as it’s drying, and my skin is clear. I use the moisturizer-defferin-moisturizer philosophy. My skin is even clear from hormonal acne. I use it very sparingly. A little goes a long way. It doesn’t smell like anything. If you do decide to use this on its own, it can be extremely drying. It’s clear in consistency, so I don’t notice any streakiness. It’s not oily either. The bottle is very effective at getting all the product out. Definitely recommend if you are battling with mild to medium breakouts. It also really helps with pore size. I have larger pores and it’s really shrunk the appearance of them. NOTE: If you go into the sun without sunscreen (or even with) it can make your skin more susceptible to sunburn. I did learn this the hard way.
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Reviewed in the United States on July 10, 2025 by Samantha S. Samantha S.
Style: Tube
Size: 45g (Pack of 2)
I've bought this product many... MANY times, and I will be the first to tell you that I am someone who has literally tried every single product under the sun to get rid of acne, no matter the price. THIS is the ONLY product that actually WORKS!!! I have completely clear skin as a result of it. It takes a few weeks to work. It doesn't work overnight. And, you have to put this stuff all over your entire face when using it, not just on the acne spots. At first, your skin will get really dry, but the end results are WORTH IT!!! I take my makeup off at night and use the Differin face wash, then apply a thick layer of this stuff throughout my entire face. I bought it here because for a tube literally a quarter of the size of one of these tubes, it's the same exact price at my local Walmart. HIGHLY RECOMMEND! TRY IT!
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Reviewed in the United States on June 7, 2025 by Trina