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SkinMedica Retinol Serum 1.0 Complex - Serum for Face, Age-Defying Advanced Retinol Cream That Renews Skin and Diminishes the Appearance of Fine Lines and Wrinkles - 1 Fl Oz

  • Based on 2,818 reviews
Condition: New
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Availability: In Stock.
Fulfilled by Amazon

Arrives Aug 31 – Sep 10
Order within 18 hours and 16 minutes
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Set name: 1.0 Complex Set


Features

  • Advanced Retinol Formula - Infused with Vitamin A derivatives, this high-potency retinol face serum helps support skin renewal and reduces the appearance of fine lines and wrinkles for a more youthful complexion.
  • Encapsulated PhytoShield Complex - Enriched with a unique antioxidant blend, this retinol serum is designed to help enhance skin texture while minimizing irritation, ensuring smoother, healthier-looking skin.
  • Improves Skin Tone & Texture - This brightening serum helps refine skin resiliency, promoting the look of a radiant and even complexion while addressing concerns like dullness.
  • The term Age Defense that is showing on the secondary packaging is referring to the product grouping this material falls within such as age defense, moisturize, etc.

Description

Revitalize your skin and reduce the appearance of fine lines with this advanced retinol formula. Designed for all skin types that have been pre-conditioned with Retinol Complex 0.25 or a similar retinoid, this product works to visibly improve skin tone, texture, and resilience. It features the exclusive PhytoShield™ Complex, an antioxidant blend that supports enhanced texture and helps minimize irritation. Powered by Retinol, it stimulates collagen production and accelerates cell renewal, effectively diminishing the appearance of fine lines and coarse wrinkles for rejuvenated, healthier-looking skin. Brand Story Improve the appearance of skin with effective formulas that help address the many factors that lead to premature aging. SkinMedica’s three varying strengths of retinols enhance skin’s radiance, tone, texture, and resiliency.

Is Discontinued By Manufacturer ‏ : ‎ No


Product Dimensions ‏ : ‎ 1.65 x 5.65 x 1.65 inches; 2 ounces


Item model number ‏ : ‎ 94926


Department ‏ : ‎ YES


UPC ‏ :


Manufacturer ‏ : ‎ SkinMedica


Best Sellers Rank: #3,313 in Beauty & Personal Care (See Top 100 in Beauty & Personal Care) #143 in Facial Serums


#143 in Facial Serums:


Customer Reviews: 4.6 4.6 out of 5 stars (2,820)


Frequently asked questions

If you place your order now, the estimated arrival date for this product is: Aug 31 – Sep 10

Yes, absolutely! You may return this product for a full refund within 30 days of receiving it.

To initiate a return, please visit our Returns Center.

View our full returns policy here.

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Top Amazon Reviews


  • Great product. Don't think it twice to get it.
Set name: 1.0 Complex Set
I was using the .5 and started with the 1.0 just a week ago. I can see the difference in just one week. I have mix skin with acne scars and sun marks. Skin got softly peeled and already got a firmer and smoother look. I highly recommend but judging for it's immediate action I would say to take breaks for sensitive skins in between usage. For the rest this product is high quality. Highly recommended. ... show more
Reviewed in the United States on March 16, 2026 by Cristina Burgos Otero

  • Effective retinol with no prescription
Set name: 1.0 Complex Set
I’ve been using SkinMedica Retinol 1.0 for several months and the results are impressive. This is definitely the best retinol you can buy without prescription. Best for people who already have experience with retinoids, not recommended for beginners . The first days I had some redness and flaking, which is normal for a 1.0% retinol. After few weeks of using my skin looked much smoother, pores appeared smaller, and my overall tone became more even. I use it only at night with a rich moisturizer. You must use sunscreen daily ... show more
Reviewed in the United States on May 10, 2026 by vincenzo

  • Seems expensive, but I took a chance and am very pleased with this product.
Set name: 1.0 Complex Set
Expensive, but worth the price. I have found it difficult to find an over the counter retinol product that works. This seems effective. I found that using it daily did dry my face and I had some minor peeling, but after that initial phase those effects resolved. I have fairly sensitive skin and I am tolerating it well. I do use a good moisturizer. If it seems to irritating starting with applications less frequently, as most retinol products recommend, should help ease your skin into it. The pump dispenses a small drop per pump and that is enough for my face and neck. I will purchase this again, although this bottle should last quite a while given the small amount used for each application. ... show more
Reviewed in the United States on April 23, 2026 by Pearl

  • Amazing product, but be careful, this is no joke
Set name: 1.0 Complex Set
This is truly an amazing product. I have used prescription Retin-A products and a handful of others and this one has them all beat hands down. It is made by the same company that makes Botox, which for me means something. This transformed my skin in a matter of days. It was extremely astonishing. It must be their delivery system encapsulated with antioxidants. Whatever it is, this stuff works. However much like most of the other reviews on here, this stuff is no joke and is very strong. I can say I had less skin irritation overall with this product over any other similar product I have tried, including prescription products. However I still experienced some redness, extreme dryness, and very little peeling. Like most retinoids, this product will dehydrate your skin like a desert. I found myself layer on moisturizer several times a day and my skin just drank it like water when using this product. So although extremely effective, be prepared to add things to your routine which deeply moisturize your skin. Eventually I moved from daily use to every other day and that seemed to help a lot with the irritation in general and over drying. The over drying isn't a normal skin drying. It makes your skin sort of the text of a porcelain doll..and it looks like one also. So just imagine having to apply moisturizer to a porcelain doll and you can see how this sort of changes your skin and demands constant nourishment. I added a moisturizing face mask, which also made a huge difference although I do not do that regularly. ... show more
Reviewed in the United States on March 22, 2016 by EtrangerDC

  • Works but beware!
Set name: 1.0 Complex Set
I’ve been using the 0.5 retinol of this brand for a few months and thought I should upgrade to the 1%. With the 1% I experienced burning around my neck and mouth that lasted 24hrs after applying. Then, I experienced peeling 3 days after application for at least a week. At first I thought I was having an eczema flair up until I realized it was the retinol. During the peeling stage I made sure to use a gentle facial cleanser, cold water, and apply creams for eczema. After the peeling faze, I had a reduction of my hyperpigmentation from acne and my skin over all looks brighter and fresh. I was using it twice a week, but I’m probably going to drop back to the 0.5 for a while. Tl;dr if you have sensitive skin your face will definitely burn and peel. Make sure to moisturize, apply that sunblock, and avoid any irritants (dust, pet hair, perfumes, makeup, ect) during the peeling faze. ... show more
Reviewed in the United States on December 25, 2024 by Amazon Customer

  • it's the best!
Set name: 0.5 Complex Set
Non-irritating when used over my normal moisturizer at night, and I was nervous about it since I just bumped up my % from 0.25 to 0.50. Product lasts a while and is worth the $.
Reviewed in the United States on May 27, 2026 by A LAW

  • Works!
Set name: 0.5 Complex Set
Solid retinol product albeit quite strong. I only use it two times a week but I'm very happy with it.
Reviewed in the United States on February 9, 2026 by S. Madonna

  • It works
Set name: 1.0 Complex Set
I think this stuff really works. My skin does seem smoother with fewer wrinkles showing. Retinol is the only chemical that's been tested to work. It's expensive, and I wouldn't recommend it for delicate skin, but it works for me.
Reviewed in the United States on April 28, 2026 by Debra B.

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