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Ortho

Ortho Home Defense Insect Killer for Indoor & Perimeter Refill2, 1 gal.

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Availability: In Stock.
Fulfilled by Amazon
Arrives Saturday, Oct 3
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Color: Small Refill


Features

  • INDOOR INSECT KILLER: Ortho Home Defense Insect Killer for Indoor & Perimeter2 is a pest control spray that kills the toughest home-invading insects, including ants, cockroaches, spiders, fleas, ticks, scorpions, earwigs, and more as listed
  • LONG-LASTING PROTECTION: This bug spray for homes creates an indoor bug barrier that provides up to 12 month protection against ants, roaches and spiders when applied indoors on non-porous surfaces
  • WHEN TO USE: Apply this outdoor and indoor bug spray bug killer anytime as a preventative treatment, or after you see evidence of insect activity
  • WHERE TO USE: Use this insect spray indoors in kitchens and bathrooms or around doors and windows, and outdoors to the perimeter of foundations, patios, decks, garages or wherever insects are a recurring problem
  • CONVENIENT OUTDOOR & INDOOR PEST CONTROL REFILL: This 1 gal. Ortho Home Defense Insect Killer for Indoor & Perimeter Refill2 allows you to reuse your Comfort Wand from its original container

Description

Ortho Home Defense Insect Killer for Indoor & Perimeter Refill2 kills common household bugs such as ants, beetles, centipedes, cockroaches, crickets, fleas, flies, millipedes, mosquitoes, moths, spiders, stink bugs, ticks, termites, periodical cicadas and more (as listed). This bug killer spray creates a bug barrier for up to 12 months of barrier protection against ants, roaches and spiders indoors on non-porous surfaces. Plus, the Invisi-Shield Technology formula gives off no fumes, dries clear and dries fast. DIY homeowners can use this outdoor and indoor pest control spray product anytime as a preventative treatment or after you see evidence of insect activity for long lasting-control. Apply indoors in kitchens and bathrooms or around doors and windows, and outdoors to the foundation perimeters, patios, decks, garages and wherever insects are a recurring problem. For indoor surfaces, hold sprayer 12 inches from surface being sprayed and apply a 4-inch wide band, or use a 12-inch wide band when applying outdoors to a home perimeter. Area should be sprayed until slightly wet without soaking. People and pets may re- enter the treated area once sprays have dried. Trust Ortho insect control spray with DIY pest control, home protection and indoor insect control to keep bugs out of your home.

Item Form: Liquid


Item Weight: 42.5 pounds


Liquid Volume: 1 gallons


Active Ingredients: Bifenthrin, Zeta-Cypermethrin


Brand: Ortho


Brand Name: Ortho


Unit Count: 128 Fluid Ounces


UPC: 071549000615 071549000622


Global Trade Identification Number: 15


Included Components: Insect Killer


Item Type Name: Insect Killer


Manufacturer: Scotts Miracle Gro


Model Number: 4660005


Part Number: 4660005


Item Form: Liquid


Target Species: Insects


Item Weight: 42.5 pounds


Liquid Volume: 1 gallons


Active Ingredients: Bifenthrin, Zeta-Cypermethrin


Frequently asked questions

If you place your order now, the estimated arrival date for this product is: Saturday, Oct 3

Yes, absolutely! You may return this product for a full refund within 30 days of receiving it.

To initiate a return, please visit our Returns Center.

View our full returns policy here.

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Top Amazon Reviews

    • Works Well and Easy to Apply - Good for Preventative Use
Color: Small Refill (1-Pack)
I’ve been using this as a refill for the Ortho Home Defense system, and it’s been working really well. It’s easy to use with the wand, and I like that you can apply it both indoors and around the perimeter of the house without a complicated setup. I haven’t had any issues with leakage. I mainly use it as a preventative treatment, and it does a good job keeping bugs from becoming an issue in the first place. It dries fairly quickly and doesn’t leave a strong smell, which is important when using it inside. The gallon size is a nice quantity and also lasts a while, so it’s a good value if you’re treating multiple areas. I think that this is a reliable option for home pest control that’s simple to apply, effective, and great for keeping bugs under control before they become a problem. ... show more
Reviewed in the United States on April 4, 2026 by Davira's Discoveries
    • Working good so far
Color: Small Refill (1-Pack)
Reliable and effective. This refill works perfectly with the original sprayer and provides long‑lasting protection around the home. It dries quickly, has a light scent, and noticeably reduces ants and roaches. Great value for a full gallon.
Reviewed in the United States on September 2, 2026 by C. Jasso
    • Great insect killer!
Color: Small Refill (1-Pack)
We use this product every year. Very effective. Great price!
Reviewed in the United States on August 30, 2026 by Theresa Monchunski
    • Great in the battle against bugs
Color: Small Refill (1-Pack)
By itself it might not win the war (depending on your layout and what pests you're fighting) but important to have in your arsenal for sure. It stopped ants, spiders, roaches, and stink bugs from walking under the door. You just sweep up their attempts because it works while you go on about your day/night. It works best with the Craftsman battery operated replacement sprayer cap. ... show more
Reviewed in the United States on September 4, 2026 by Sunshine
    • Effective Pest Control with Minor Drawbacks
Color: Small Refill (1-Pack)
Ortho Home Defense Insect Killer is a reliable solution for keeping common household pests at bay. It effectively targets ants, roaches, spiders, and other listed insects, providing long-lasting protection when applied correctly. The Home Depot +4 YouTube +4 Amazon +4 ✅ Pros: Effective Pest Control: Kills a wide range of insects, including ants, roaches, spiders, fleas, ticks, scorpions, beetles, silverfish, centipedes, and millipedes. Long-Lasting Protection: Provides up to 365 days of protection on non-porous surfaces. Ease of Application: Comes with a Comfort Wand that allows for easy application without bending or pumping. Amazon Amazon +1 The Home Depot +1 ⚠️ Cons: Mixed Results on Effectiveness: Some users have reported that the product is less effective on certain pests or in specific conditions. Battery Operated Wand Issues: A few customers have experienced issues with the battery-operated spray wand, including short battery life and inconsistent spray patterns. The Home Depot +1 The Home Depot +1 💡 Tips for Best Results: Apply to Entry Points: Focus on spraying around doorways, windows, and other potential entry points to create a barrier against pests. Reapply as Needed: While the product offers long-lasting protection, reapplication may be necessary in areas with high pest activity. The Spruce +7 Ortho +7 Reddit +7 Final Verdict: Ortho Home Defense Insect Killer is a solid choice for homeowners seeking an effective and easy-to-use pest control solution. While there are some minor drawbacks, its overall performance and convenience make it a worthwhile option for maintaining a pest-free home. ... show more
Reviewed in the United States on August 4, 2025 by Gregory Dornbush
    • Effective and easy
Color: Small Refill (1-Pack)
I use this in between exterminator visits and it’s effective. I use it outside by the doorways and around the perimeter of the property and inside by the doorways. It’s been safe for my pets and keeps the creepy-crawlies away. Seems less effective for spiders, because those slip through every now and then. 😭 ... show more
Reviewed in the United States on July 5, 2026 by Kathy K
    • Perfect for ants and other insects
Color: Small Refill (1-Pack)
Great product for inside and outside. Quick dry time and no odor. Works very well against ants.
Reviewed in the United States on August 23, 2026 by aravia riddick
    • The refill is considerably more economical if you already possess the sprayer
Color: Small Refill (1-Pack)
The product assists in combating the pervasive ant infestations plaguing South Texas. With ants now seemingly favoring our vehicles, it offers a somewhat temporary barrier to deter their intrusion and facilitate the relocation of their queen. We also use this around our home and it tends to keep unwanted insects away as designed. ... show more
Reviewed in the United States on July 26, 2026 by Robo

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