Search  for anything...

Life Extension Melatonin IR/XR 120 Capsules - Immediate & 7 Hour Extended-Release - Night Time Supplement - Supports Staying Asleep - Non-GMO, Gluten-Free

  • Based on 481 reviews
Condition: New
Checking for the best price...

Buy Now, Pay Later


As low as $4 / mo
  • – 4-month term
  • – No impact on credit to apply
  • – Instant approval decision
  • – Secure and straightforward checkout

Ready to go? Add this product to your cart and select a plan during checkout.

Payment plans are offered through our trusted finance partners Klarna, Affirm, Afterpay, Zip, Apple Pay, and Google Pay. No-credit-needed leasing options through Acima may also be available at checkout.

Learn more about financing & leasing here.

Free shipping on this product

Non-returnable due to Food safety reasons

View our full returns policy here.


Availability: In Stock.
Fulfilled by Amazon

Arrives Saturday, Sep 19
Order within 17 hours and 40 minutes
Available payment plans shown during checkout

Protection Plan Protect Your Purchase
Checking for protection plans...

Features

  • TWO IN ONE FORMULA - Unlike standard melatonin supplements, this premium formula delivers BOTH immediate melatonin PLUS an delayed release to help you stay asleep.
  • EXTENDED RELEASE - Melatonin IR/XR contains 1.5 mg of MicroActive Melatonin, an innovative blend of immediate-and extended-release melatonin to help you fall asleep quickly and stay asleep all night long.
  • IMMEDIATE RELEASE - Taken about 30 minutes before bed, Melatonin IR-XR helps you fall asleep quickly with fast actinng melatonin. Just one melatonin pill provides approx. seven hours of uninterrupted sleeping support, so you soundly rest throughout the night.
  • MANUFACTURERED IN THE USA - This sleeping supplement is sourced using the finest raw ingredients w/ the purity & potency your body deserves. This product is Certified Non-GMO and Gluten-Free.
  • LIVE YOUR HEALTHIEST LIFE - For over 40 years, the LE Foundation has been developing advanced, effective formulas made with the highest standards and based on the latest scientific findings. We believe the answers to a healthier, richer life are within reach and that rigorous scientific research is the path to get us there. Our formulations are created using the exact ingredients and dosages used in the studies that inspired them, ensuring that maximum bioavailability and efficacy is achieved.

Description

LifeExtension Melatonin Supplement Caps - IRXR with 1.5 mg of MicroActive Melatonins ✔ Gluten free ✔ Non-GMO TWO IN ONE SLEEP ENHANCEMENT ✔ Fast Acting, Immediate Release Melatonin ✔ Extended Release Melatonin for up to 7 hours Combined, it helps you fall asleep and stay asleep all night long. Benefits Of Micro Active Melatonin ✔ Formulated to provide approximately seven hours of support ✔ Convenient one-before-bed capsule Support To Fall Asleep & Stay Asleep, All Night Long A lack of quality, restful sleep can affect cognitive health, metabolic health and more. Poor sleep can mean that you have trouble falling asleep, but it can also mean that you wake up in the middle of the night and can't get back to sleep. Melatonin IR/XR is the perfect sleep support supplement for those who have already tried melatonin but still had trouble getting to sleep or staying asleep. Also available in 60 count I.R. E.X. bottle from LE Foundation. Do you want to fall asleep and wake refreshed? For those who sometimes have difficulty sleeping and have tried other melatonin supplements to no avail, now there’s a new formulation from Life Extension. Get the quality, restful and uninterrupted sleep your body needs. Add to your cart because you deserve feel rested in the morning.

Package Dimensions ‏ : ‎ 4.33 x 1.93 x 1.89 inches; 1.45 ounces


Date First Available ‏ : ‎ August 5, 2022


Manufacturer ‏ : ‎ Life Extension


Best Sellers Rank: #12,065 in Health & Household (See Top 100 in Health & Household) #138 in Herbal & Nutritional Sleep Supplements


#138 in Herbal & Nutritional Sleep Supplements:


Customer Reviews: 4.4 4.4 out of 5 stars (481)


Brand Name: Life Extension


Item Form: Capsule


Product Benefits: Sleep Support, Seven Hours of Healthy Sleep Support, Anti-Aging


Age Range Description: Adult


Number of Items: 1


Container Type: Bottle


Dosage Form: Capsule


UPC: 737870220114


Manufacturer: Life Extension


Manufacturer Part Number: 02201-120


Unit Count: 120 Count


Item Weight: 0.04 kg


Allergen Information: Gelatin


Frequently asked questions

If you place your order now, the estimated arrival date for this product is: Saturday, Sep 19

This item is non-returnable:

Non-returnable due to Food safety reasons

View our full returns policy here.

  • Klarna Financing
  • Affirm Pay in 4
  • Affirm Financing
  • Afterpay Financing
  • Zip Pay in 4
  • Financing through Apple Pay
  • Financing through Google Pay
Leasing options through Acima may also be available during checkout.

Learn more about financing & leasing here.

Top Amazon Reviews


  • Extended release has been a game changer
Trying the Bredesen protocol for my dad with dementia. Dr told me to use an extended release Melatonin to help him stay asleep. We were using regular melatonin before which would get him to bed but then he would wake up. This has helped let him sleep through the night. Love the dose as well. Been very hard to find lower doses of melatonin. Your body naturally only makes about ~0.3mg of melatonin. Happy with this product so far. ... show more
Reviewed in the United States on August 11, 2026 by Carmen Salem

  • Excellent Remfresh replacement. Best time release melatonin
I’ve used a lot of different brands of melatonin. For many years, I used Remfresh because it was the longest lasting melatonin I’d found. But Nestlé bought Remfresh and stopped making it. After about a year of searching for a replacement I finally found this. I think it is better than Remfresh actually. The combination of fast acting and time release is nice. But the best part is it works a full 7 hrs or even a little more. It works so well that I’ll use regular time release melatonin instead if I can only get 6 or less hrs of sleep. I highly recommend this melatonin if you have trouble going back to sleep when you wake up in the middle of the night. ... show more
Reviewed in the United States on August 10, 2026 by ethios4

  • It has way too much melatonin
It works as advertised. The dose of 1.5 mg perfectly fine. There is no reason for the melatonin in the 10mg doses. There is data that shows that the small doses are just as effective as the larger ones.
Reviewed in the United States on July 15, 2026 by Hook

  • Best Melatonin I've found
I like the combination of the extended and quick release, and it does help me sleep, but not as well as I'd like. I have intermittent insomnia and this has not eliminated it. To be fair, I take two other prescription meds and magnesium. So, I can't blame it all on the Melatonin.
Reviewed in the United States on January 8, 2026 by Paul H

  • More sound sleep.
The extended release helps me get 5-6 hours of lights-out sleep. I was only getting 4-5 hours before when I took Ashwandagha and B6.
Reviewed in the United States on August 22, 2026 by Placeholder

  • Try it. You won't regret it
It really works!
Reviewed in the United States on August 5, 2026 by Jo

  • Best melatonin I have tried
This is hands down the best melatonin product I have tried and trust me when I say I have tried many different versions from different manufacturers and a wide gamut of dosages and delivery methods. Despite it’s modest dosage compared to many other products, this melatonin is so much more stable throughout the night compared to other extended release products and causes no hangover effect as many high dosage melatonin capsules often cause. It’s more expensive per milligram than many other products, but it just works the best. ... show more
Reviewed in the United States on April 17, 2026 by P. Leblanc

  • No help for sleeping
Very disappointed in Melatonin IR/XR. I've taken regular melatonin, on and off again, thru the years. As a VN vet, I've had trouble sleeping longer than 2 to 3 hours at a time. The regular melatonin, lasts about 2.5 hours and then I'm awake. Our doctor recommended this product! It did nothing for me. Taking it by itself was like taking nothing. Fortunately, I now fall asleep relatively quick, hopeing this would keep me asleep for maybe 4 or 5 hours, but no, it didn't. I would have been thrilled if it worked and surprised, only 1.5 melatonin. ... show more
Reviewed in the United States on August 1, 2025 by Linda K.

Can't find a product?

Find it on Amazon first, then paste the link below.
Checking for best price...