Search  for anything...

iS CLINICAL Active Serum - Visibly evens skin tone, Excellent for acne-prone skin, Anti-Aging Face Serum

  • Based on 827 reviews
Condition: New
Checking for the best price...
$148.00 Why this price?

Buy Now, Pay Later


As low as $24.67 / mo
  • – 6-month term
  • – No impact on credit
  • – Instant approval decision
  • – Secure and straightforward checkout

Ready to go? Add this product to your cart and select a plan during checkout.

Payment plans are offered through our trusted finance partners Klarna, PayTomorrow, Affirm, Afterpay, Apple Pay, and PayPal. No-credit-needed leasing options through Acima may also be available at checkout.

Learn more about financing & leasing here.

Selected Option

Free shipping on this product

30-day refund/replacement

To qualify for a full refund, items must be returned in their original, unused condition. If an item is returned in a used, damaged, or materially different state, you may be granted a partial refund.

To initiate a return, please visit our Returns Center.

View our full returns policy here.


Availability: In Stock.
Fulfilled by LovelySkin Inc

Arrives Aug 2 – Aug 3
Order within 5 hours and 56 minutes
Available payment plans shown during checkout

Style: iS CLINICAL Active Serum, 1 fl. oz.


Skin Type: Combination, Dry, Normal


Product Benefits: Improves the appearance of uneven skin tone, wrinkles, fine lines and acne. Smooths and softens the skin See more


Use for: Face


Scent: Aloe


Special Ingredients: vitamin_a, salicylic_acid


Is Discontinued By Manufacturer ‏ : ‎ No


Product Dimensions ‏ : ‎ 2.88 x 1.63 x 4 inches; 1.06 ounces


Item model number ‏ : ‎ 1007


UPC ‏ :


Manufacturer ‏ : ‎ iS CLINICAL


Frequently asked questions

If you place your order now, the estimated arrival date for this product is: Aug 2 – Aug 3

Yes, absolutely! You may return this product for a full refund within 30 days of receiving it.

To initiate a return, please visit our Returns Center.

View our full returns policy here.

  • Klarna Financing
  • Affirm Pay in 4
  • Affirm Financing
  • Afterpay Financing
  • PayTomorrow Financing
  • Financing through Apple Pay
Leasing options through Acima may also be available during checkout.

Learn more about financing & leasing here.

Top Amazon Reviews


  • LOVE IS Clinical!
Style: 0.5 Fl Oz (Pack of 1)
I love IS clinical product. Specifically the active serum and hydra cool. Active serum is great for reducing the look of dark spots on your face and reduces the size of pores. Highly recommend as part of your daily routine. I've been using this product for years. It is pricey, but definitely worth it! ... show more
Reviewed in the United States on May 23, 2025 by Kara York

  • Holy grail
Style: iS CLINICAL Active Serum, 1 fl. oz.
This is by far the most expensive skincare product I've ever purchased, but it is so worth it. I got a sample a few months ago at an event. That sample size lasted me about a week. Maybe about 4-5 days into the week, I saw myself in the mirror and was like, whoa. My skin had never been so clear, even toned, less fine lines, and just healthy looking. I looked into the product at the time to purchase and was like, damn, that's a lot. Didn't get it, didn't think much about it but then started thinking about it the other day. I almost bought from a different vendor because they had a 30% off coupon but then when I looked at IS Clinical's website, that vendor was not an authorized seller. I wanted to make sure I was getting the authentic stuff, so I bit the bullet. Ordered from Amazon because they're an authorized seller per IS Clinical's site, and you can't beat Amazon's shipping time. Ordered it a couple nights ago and was at my door bright and early the next morning. I also ordered the face wash, which I hadn't tried before. ... show more
Reviewed in the United States on February 28, 2025 by Sarah

  • Game Changer, clear skin
Style: 0.5 Fl Oz (Pack of 1)
This serum has changed my face tremendously. I call it the magic potion.
Reviewed in the United States on May 27, 2025 by vivian

  • Acne good
Style: 0.5 Fl Oz (Pack of 1)
Clears breakout
Reviewed in the United States on May 23, 2025 by Uyi Osawe

  • Great product – works as promised!
Style: iS CLINICAL Active Serum, 1 fl. oz.
I really liked this product. I've been using it for a few days and I'm already noticing noticeable improvements – my skin is becoming more hydrated and fresher. The texture is pleasant, non-sticky and absorbs quickly. It has a light, subtle fragrance that is not too strong. The packaging is convenient, and the pump works flawlessly. I think it is suitable for both dry and normal skin. It really exceeded my expectations – I will definitely order it again! ... show more
Reviewed in the United States on March 28, 2025 by Arina

  • LOVE
Style: 0.5 Fl Oz (Pack of 1)
Love IS CLINICAL! I’ve never been disappointed with any of their products. They’re pricey, but they work. The IS CLINICAL Active Serum lives up to its name. I have acne-prone skin, I’ve never had any issues with anything from IS CLINICAL. I use it at night, it has a very thin, light consistency. If you’re on the fence about trying it, just buy it. You won’t be disappointed! ❤️ ... show more
Reviewed in the United States on December 30, 2024 by Ashley Gouner ❤️

  • IS Clinical
Great product. Already on my 3d 1 oz bottle. Lasts 3 months which is good value. I have a combination skin type with occasional break outs + areas of hyperpigmentation. I do not have many wrinkles as yet. So the main difference I saw in overall improvement of skin quality. It cleared 99% of breakouts and made hyperpigmentation slightly less visible, though no dramatic changes here. Great overnight serum as do not need to apply anything else and skin looks and feels great in the morning. Will highly recommend this product and will start trying others from the same line. ... show more
Reviewed in the United States on April 12, 2012 by Inna

  • Wonderful!
Style: 0.5 Fl Oz (Pack of 1)
This is a great product. I had been searching for a serum that wouldn't make me breakout or cause redness. My skin is super sensitive. This is the one. My skin has smoothed, evened and glows. People who have not seen me for a while , commented on how youthful I look, and me with gray hair. They tell me I look 40/45. I am 67! Thank you iS clinical! ... show more
Reviewed in the United States on September 10, 2024 by Hurting Feet

Can't find a product?

Find it on Amazon first, then paste the link below.
Checking for best price...