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Frontline

FRONTLINE Plus Flea & Tick Spot Treatment for Medium Breed Dogs 23-44 lbs. (Blue) Count of 8

  • Based on 24,157 reviews
Condition: New
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Availability: In Stock.
Fulfilled by Amazon
Arrives Monday, Oct 26
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Style: 8 Count


Features

  • The #1 name in flea and tick protection
  • Trusted by pet owners for over 20 years**
  • Fast-acting, long-lasting flea and tick treatment thats waterproof 24 hours after application
  • Protects from fleas and ticks for a full month
  • Kills adult fleas, flea eggs, flea larvae, ticks, and chewing lice
  • Aids in the control of sarcoptic mange infestations
  • Stops existing flea infestations and prevents establishment of new infestations

Description

Keep your dog protected with the number 1 name in flea & tick protection (1), FRONTLINE. FRONTLINE Plus for Dogs is a fast-acting, long-lasting waterproof flea & tick topical that's proven to kill fleas, flea eggs, flea larvae, chewing lice, and ticks that can transmit Lyme disease. Break the flea life cycle — FRONTLINE Plus for Dogs is specially formulated with fipronil and (S)-methoprene to kill existing adult fleas, flea eggs and flea larvae to guard against further infestations for flea control. Trusted by pet owners for over 20 years (2) — FRONTLINE Plus for Dogs can be used on puppies as young as eight weeks old, weighing 5 pounds or more, and is easy to apply. Applied to a single point on your pet, the flea and tick control treatment covers your dog's entire body and deposits in the sebaceous glands. These glands act as a reservoir, continuously replenishing the treatment onto your pet, working even if your dog gets wet. Just one dose of FRONTLINE Plus each month protects against fleas & ticks for a full 30 days. FRONTLINE Plus also comes in a formula designed for cats and kittens eight weeks of age and older, 1.5lbs. and over so you can protect the dogs or cats in your house from fleas and ticks with FRONTLINE Brand Products. Appropriately treat all pets in your household monthly to effectively control fleas and ticks and prevent the establishment of new flea infestations. Subscribe and save today to make it easier to keep your dogs or cats protected year-round and make sure you never run out of FRONTLINE Plus. Be sure to visit our brand store and follow us to stay up to date on new FRONTLINE products, features, tips and more. References: (1) BI Marketing Excellence Survey performed by Kynetec, November 2023. (2) 20 years of trust in killing fleas and ticks demonstrated by various studies in the past 20 years including a 2002 Pet Owner Brand Awareness and Attitude Tracking Study performed by Bruno and Ridgway Research Associates and the 2023 BrandSpark© American Trust Study where FRONTLINE Brand Products were voted most trusted for brand for flea & tick prevention.

Brand: Frontline


Item Form: Liquid


Scent: Unscented


Item Weight: 9.07 g


Active Ingredients: fipronil and (S)-methoprene


Item Volume: 6 ml


Allergen Information: Gluten Free


Dog Breed Size: Medium


Unit Count: 1 Count


Color: Blue


Product Dimensions ‏ : ‎ 0.63 x 5.75 x 4.5 inches; 0.32 ounces


Item model number ‏ : ‎ 72218


Date First Available ‏ : ‎ February 7, 2019


Manufacturer ‏ : ‎ Boehringer Ingelheim Animal Health


Best Sellers Rank: #1,001 in Pet Supplies (See Top 100 in Pet Supplies) #10 in Dog Flea Drops


#10 in Dog Flea Drops:


Customer Reviews: 4.4 4.4 out of 5 stars (24,157)


Brand Name: Frontline


Unit Count: 1 Count


Age Range Description: All Life Stages


UPC: 611030624557 350604062455


Included Components: Applicator


Item Type Name: Topical


Manufacturer: Boehringer Ingelheim Animal Health


Model Number: 72218


Manufacturer Part Number: 65331-5


Warranty Description: If you are not satisfied with Frontline Plus for any reason, please contact the Boehringer-Ingelheim Animal Health Customer Care Team at .


Item Form: Liquid


Scent Name: Unscented


Dog Breed Size: Medium


Target Species: Medium Dog, 23-44 Pounds


Item Weight: 9.07 g


Volume: 6 ml


Allergen Information: Gluten Free


Active Ingredients: fipronil and (S)-methoprene


Frequently asked questions

If you place your order now, the estimated arrival date for this product is: Monday, Oct 26

This item is non-returnable:

Non-returnable. Transportation of this item is subject to hazardous materials regulation

View our full returns policy here.

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Top Amazon Reviews

    • Tick and flea repellent
Style: 8 Count
It really works! Never used one before. I found 2 dead ticks laying on the floor at first. No ticks or fleas afterwards!! Great product. My dogs will not be without it!!
Reviewed in the United States on September 3, 2026 by Placeholder
    • Excellent product, BUT...
Style: 6 Count
This is an excleent product, but it is not a miracle worker. In other words, you need to use the stuff properly. (1) this product is water resistant...not soap resistant. So if you use this stuff then go and use some of that heavily perfumes soapy shampoo that msot people use..then you are washign it right off. (2) if you chose to bathe your dog..bathe him/her first then wait 2-3 days THEN apply the product so that it will be distrubited properly. (3) Remember that if you have a heavy flea problem that you need to treat the pet and the environment. You can't jsut put it on the dog and not get rid of the fleas in your house, car, yard, etc.. Yeah it will kill the fleas on him/her, but they will get reinfested with fleas everytime they go back into the flea filled environment. This is the only product that I use for my dog. Of you purchase ANYTHING over the counter (biospot, hartz ::shudders::, etc) then you are wasting your money. Flea dips work, but they only kill the fleas that are on the dog when you bathe him/her. Frontline PLUS is great becasue it keeps killing for up to a month. Also, Frontline Plus has a better range of killing fleas than plain ole' Frontline. The "PLUS" means that it kills larvae and eggs and so much more than adult fleas. IF USED CORRECTLY and ROUTINELY this is an EXCELLENT product!!! I highly recommend it. This product also kills ticks. ... show more
Reviewed in the United States on December 17, 2008 by Brina
    • Great for dogs with allergies.
Style: 6 Count
Works great!! I have a dog with allergies and she quits scratching as soon as I apply the Frontline.
Reviewed in the United States on August 29, 2026 by Dawn
    • Trusted protection, but effectiveness can vary by region
Style: 3 Count
This is a well-known and trusted flea & tick treatment that’s easy to use and works as part of a monthly routine. Each application provides about 30 days of protection, and the formula is designed to kill adult fleas, eggs, larvae, ticks, and even chewing lice. Application is simple—just apply it to the back of your dog’s neck, and it spreads through the oils in the skin for full-body protection. It’s also waterproof after drying, which is helpful for active dogs. In terms of performance, it works well for many dogs and can kill adult fleas within about 12 hours and ticks within 48 hours, helping break the flea life cycle. On the downside, effectiveness can vary depending on your area—some users report it’s not as strong as it used to be, especially in high-flea regions. It can also take a full day or so to start working, and you’ll need to stay consistent with monthly use. ... show more
Reviewed in the United States on April 13, 2026 by Amanda D.
    • Nothing to tick about
Style: 3 Count
Excellent for the summer issues down south works like a charm. Would definitely recommend buying this product for your four legged family members.
Reviewed in the United States on September 5, 2026 by Antonio's
    • Frontline flea protection
Style: 3 Count
Good product! It works!
Reviewed in the United States on September 4, 2026 by Wilda Bisesi-Hahn
    • Bad batch
Style: 3 Count
Didn't work. I have bought front line for years for my dogs and it's always done me good in the past. This batch didn't. This time when I applied it, it didnt do anything and i ended up with the worst fleas I've ever had. I decided to wait a few days, I know in some cases it takes time for the medication to work. After a few days I couldn't take it anymore, the fleas were out of control. Had to pull the combination of dawn dish soap and coconut oil out to get rid of them. Normally you would buy this stuff as a deterrent or treatment but I felt like it attracted them. Now I'm wondering if I should hope that I got a bad box or maybe it's time to switch to a different flea deterrent.. ... show more
Reviewed in the United States on June 15, 2026 by Valerie
    • Did the job
Style: 3 Count
Did the job for my dog
Reviewed in the United States on September 15, 2026 by Sherry

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