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Designs for Health

Designs for Health Homocysteine Supreme - Methylated Multivitamin of B Vitamins with Riboflavin, B6, B12, Folate, L-Serine & TMG for Brain Support & Healthy Inflammatory Response (120 Caps)

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Availability: In Stock.
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Arrives Wednesday, Jun 10
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Size: 120 Count (Pack of 1)


Features

  • Methylation Support - A modified methylated B complex with L-serine and TMG, which are known to facilitate the efficient metabolism of homocysteine and normal methylation processes in the body.* Intended to promote cardiovascular health, brain function, and healthy imflammatory response.
  • Promotes Heart & Brain Health - An optimally functioning homocysteine pathway plays a role in biochemical reactions, such as detoxification, healthy immune support, ideal joint and cartilage structure, brain health and cardiovascular health.*
  • Premium B Vitamins & TMG for Superior Absorption - Supplies a methylated folate and B12 supplement, along with P5P vitamin B6 and riboflavin. Includes Trimethylglycine to support normal methylation.*
  • Vegetarian & Non-GMO - Vegetarian-friendly and made without soy, gluten, GMOs or soy. Take 2 capsules per day with meals or as directed by your health-care practitioner.
  • Clinically-Trusted Care - DFH is the #1 practitioner supplement brand recommended by functional medicine professionals and the #1 practitioner supplement brand personally trusted by functional medicine professionals.**

Is Discontinued By Manufacturer ‏ : ‎ No


Product Dimensions ‏ : ‎ 3 x 3 x 5 inches; 0.04 ounces


Date First Available ‏ : ‎ July 26, 2021


Manufacturer ‏ : ‎ Designs for Health


Best Sellers Rank: #8,100 in Health & Household (See Top 100 in Health & Household) #158 in Blended Vitamin & Mineral Supplements


#158 in Blended Vitamin & Mineral Supplements:


Customer Reviews: 4.7 4.7 out of 5 stars (899)


Brand Name: Designs for Health


Item Form: Capsule


Primary Supplement Type: Methylation Support Capsules


Diet Type: Gluten Free, Vegetarian


Flavor: Unflavored


Product Benefits: Heart Health Support


Age Range Description: Adult


Specific Uses For Product: Brain


Special Ingredients: B Vitamins, TMG, L-serine


Number of Items: 1


Container Type: Bottle


Dosage Form: Tablet


UPC: 879452006683


Manufacturer: Designs for Health


Unit Count: 120 Count


Item Weight: 1000 Milligrams


Item Dimensions: 3 x 3 x 5 inches


Material Type Free: Dairy Free, GMO Free, Soy Free


Frequently asked questions

If you place your order now, the estimated arrival date for this product is: Wednesday, Jun 10

This item is non-returnable:

Non-returnable due to Food safety reasons

View our full returns policy here.

  • Klarna Financing
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  • Financing through Apple Pay
Leasing options through Acima may also be available during checkout.

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Top Amazon Reviews

    • Functional medicine recommended
Size: 120 Count (Pack of 1)
Recommended by my functional medicine doctor, and it’s been great so far! Excellent quality and value, and I don’t notice any taste when taking it—which is a big plus.
Reviewed in the United States on October 18, 2025 by Tricia C.
    • Homocysteine was requested by my Doctor. The order came in a timely fashion.
Size: 60 Count (Pack of 1)
Very good product, delivery was quick. The product was what was suggested by my Doctor.
Reviewed in the United States on February 3, 2026 by DOW STEEN
    • At last, a formulation that really brings down Homocysteine levels
Size: 120 Count (Pack of 1)
At last, a formulation with all bioavailable forms of B vitamins with added TMG. Even the B6 is in the form of P-5-P, which is important for nerve health. However, I bought this to help bring down my Homocysteine, which was elevated even when taking other B Complex formulas. This really did what it says on the label as it brought my Homocysteine level back down to a healthy as shown by my blood tests. I will keep buying this as it works. ... show more
Reviewed in the United States on January 30, 2026 by Kindle Customer Chris
    • Good quality
Size: 120 Count (Pack of 1)
This product has helped me reduce my high homocysteine due to homozygous MTHFR. I highly recommend you give it a try if you have issues with methylation.
Reviewed in the United States on October 2, 2025 by Vicky
    • Homocysteine Supreme works to lower high homocysteine levels
Size: 120 Count (Pack of 1)
Excellent product for high homocysteine levels, have had no negative side effects at all, and it does provide a small boost of energy, very smooth effect, and significantly lowered my homocysteine levels.
Reviewed in the United States on August 27, 2025 by jeremy
    • No child lock
Size: 60 Count (Pack of 1)
Helps with anxiety! Good value for money. No child lock on bottle.
Reviewed in the United States on January 15, 2026 by Hope Kloepper
    • Original product, not a copy
Size: 120 Count (Pack of 1)
Faithful fulfillment of original product ... not a foreign copy
Reviewed in the United States on January 12, 2026 by James Carey
    • Homocysteine tabs
Size: 60 Count (Pack of 1)
Works as should
Reviewed in the United States on February 17, 2026 by Nancy

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