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Advantage II Large Cat Over 9 lbs & Advantage II Small Cat 5-9 lbs Vet-Recommended Flea Treatment & Prevention | 6-Month Supply Each

  • Based on 74,851 reviews
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Availability: In Stock.
Fulfilled by Amazon

Arrives Monday, Jun 23
Order within 11 hours and 47 minutes
Available payment plans shown during checkout

Size: 6-Pack


Style: with Small Cat


Features

  • Contains one 6-pack of Advantage II for Large Cats over 9 lbs and one 6-pack of Advantage II for Small Cats 5-9 lbs
  • Advantage II for cats is a leading brand in cat flea treatment and prevention for cats, at least 8 weeks of age
  • Vet-recommended, easy-to-apply monthly topical treatment no hard-to-swallow pills, no prescription needed
  • Delivers total flea protection kills adult fleas, flea larvae and flea eggs through contact
  • Same-day effectiveness kills fleas within 12 hours of application and keeps working for 30 days
  • Fragrance-free formula, waterproof after 24 hours of application

Description

Advantage II for cats is a vet-recommended, leading brand in cat flea protection. Advantage II for cats flea treatment and prevention kills adult fleas, flea larvae and flea eggs to deliver total flea protection to your cat or kitten. Within 12 hours of application, Advantage II for cats topical treatment gets straight to work killing fleas through contact, so they don’t have to bite your cat to die. This treatment works hard for 30 days following application, effectively breaking the flea life cycle, controlling existing flea infestations and preventing further infestations all month long. This convenient, spot-on application goes on the back of your cat’s neck at the base of the skull. It goes on in seconds! You’ll also love that Advantage II for cats is fragrance-free and waterproof after 24 hours of application. Advantage II for cats flea protection is effective on both indoor and outdoor cats. Advantage II for cats is a trademark of Elanco or its affiliates.

Brand: Advantage


Item Form: Topical


Scent: Unscented


Item Weight: 11.36 ounces


Active Ingredients: imidacloprid


Item Volume: 0.4 Milliliters


Age Range (Description): 8 weeks and old


Item Weight ‏ : ‎ 11.36 ounces


Date First Available ‏ : ‎ January 28, 2021


Manufacturer ‏ : ‎ Elanco


Best Sellers Rank: #59 in Pet Supplies (See Top 100 in Pet Supplies) #1 in Cat Flea Drops


#1 in Cat Flea Drops:


Customer Reviews: 4.5 4.5 out of 5 stars 74,851 ratings


Item Weight: 11.4 ounces


Manufacturer: Elanco


Date First Available: January 28, 2021


Item Weight: 11.36 ounces


Brand Name: Advantage


Target Audience Keyword: house-cats


Color: with Small Cat


Size: 6-Pack


Age Range Description: 8 weeks and old


Style: with Small Cat


Breed Recommendation: Large Breeds


Frequently asked questions

If you place your order now, the estimated arrival date for this product is: Monday, Jun 23

Yes, absolutely! You may return this product for a full refund within 30 days of receiving it.

To initiate a return, please visit our Returns Center.

View our full returns policy here.

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Top Amazon Reviews


  • Advantage II Large Cat Flea Treatment: Effective and Hassle-Free Protection!
Size: 4-Pack Style: Large Cat only
The Advantage II Large Cat Vet-Recommended Flea Treatment & Prevention (4-Month Supply, Cats Over 9 lbs.) has been a game-changer for my indoor-outdoor cat. This topical solution, backed by veterinarians, is super easy to apply—just a quick squeeze at the base of the skull, no pills required. The fragrance-free formula kills fleas, larvae, and eggs on contact within 12 hours, preventing bites and breaking the flea life cycle for a full 30 days per dose. My cat’s scratching stopped almost immediately, and I’ve noticed no fleas since starting the treatment. The 4-month supply is convenient and cost-effective, with no prescription needed, and the waterproof formula holds up after 24 hours, perfect for my cat who loves exploring. The active ingredients, imidacloprid and pyriproxyfen, work effectively without needing fleas to bite, reducing risks like tapeworm or dermatitis. Application is straightforward, though I ensure my cat doesn’t lick the spot initially to avoid mild salivation. While some users report rare skin irritation, my cat had no issues, but I’d suggest monitoring after the first use and consulting a vet for sensitive pets. For anyone with a cat over 9 lbs. needing reliable flea control, this is a solid, vet-trusted choice that delivers peace of mind and a happy, itch-free pet! Consult a veterinarian before use. ... show more
Reviewed in the United States on May 30, 2025 by Martin E.

  • Super easy, dries faster than other brands.
Size: 6-Pack Style: Large Cat only
Of all the flea and tick meds out there, this is by far the easiest to apply and the fastest to dry. I live on the east coast with all kinds of ticks in abundance. Just yesterday before applying, I had pulled three different kind of ticks off my one cat. Let's see if the solution is as powerful as other brands. I will post an update in a week or so. ... show more
Reviewed in the United States on June 11, 2025 by danielle moir

  • Effective and safe
Size: 4-Pack Style: Large Cat only
Reliable control of fleas for your cat(s). Might be old school product, but gets the job done. Have 2 cats (lighter weight cats) and ordering the product for large (higher weight) cats was able to save $$ by splitting a tube between cats. Ease of application and effective flea control. Put product on my cat as directed between shoulder blades and saw results quickly within hours of application. ... show more
Reviewed in the United States on June 5, 2025 by Amazon Customer

  • Works pretty good but doesn’t last a full month
Size: 6-Pack Style: Large Cat only
This works well enough if you don’t have active fleas in your yard or house but I usually have to reapply after three weeks during the warmer seasons. I use it for my cats because it’s one of the milder preventables and none of them have any problems tolerating it. It takes several hours to dry and a couple of my cats get a little bit of flakiness where I applied it that is temporary. It starts working fairly fast, within a few hours usually. One warning though, make sure you follow the directions of how and where to put it on so your cat doesn’t have access to lick it off. ... show more
Reviewed in the United States on June 5, 2025 by Janice

  • BEST flea medicine out there for cats!!! A+
Size: 2-Pack Style: Large Cat only
This brand is consistently RELIABLE! The only flea medicine I trust to use on my cats! Kills fleas and leaves them comfortable! Been using this product for years and 5 stars all the way!!! A++++ ⭐️⭐️⭐️⭐️⭐️
Reviewed in the United States on June 14, 2025 by Holly Turkovich

  • Highly recommend
Size: 1-Pack Style: Large Cat only
I have to say this worked within 2days after putting the application. After that no sign of scratching or anything! Highly recommended!! It helped!!
Reviewed in the United States on June 13, 2025 by Jasmin

  • Flea free kitty!
Size: 1-Pack Style: Large Cat only
Our kitty enjoys a flea free lifestyle after we apply this medication. We have been using this for several years and it seems to work better than other brands we have tried in the past. Within 24 hours, there is no more scratching. Now she has time to enjoy the more important things in life.
Reviewed in the United States on May 27, 2025 by Future Investments Future Investments

  • Unsatisfied
Size: 6-Pack Style: Large Cat only
Well, I'm unsatisfied overall. I have been using this flea and tick medicine for 4 months now and I have been pulling ticks off my cat. And just to be super specific i just reapplied meds to him a week ago and pulled two ticks off him today. Now, I have to say it's only around his eyes or crawling on his fur but I constantly have to check him. Unfortunately, for the price I was hoping for better results. Moving forward with another bread. ... show more
Reviewed in the United States on May 21, 2025 by Alayna

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