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ZO SKIN HEALTH Daily Power Defense Clinically Proven 50ml, 1.7 Fl Oz

  • Based on 913 reviews
Condition: New
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$115.97 Why this price?
Save $23.03 was $139.00

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As low as $19.33 / mo
  • – 6-month term
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30-day refund/replacement

To qualify for a full refund, items must be returned in their original, unused condition. If an item is returned in a used, damaged, or materially different state, you may be granted a partial refund.

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View our full returns policy here.


Availability: In Stock.
Fulfilled by Amazon

Arrives Tuesday, May 20
Order within 17 hours and 39 minutes
Available payment plans shown during checkout

Size: 1.7 Fl Oz (Pack of 1)


Features

  • Daily Power Defense Clinically Proven 50ml 1.7 Fl OZ

Description

Powerful antioxidant serum designed to improve the appearance of lines + wrinkles and promote overall skin health.

Skin Type: Dry


Product Benefits: Antioxidant,Firming,Replenishing


Use for: Whole Body


Scent: Orange,Lemon,Peppermint,Citrus


Brand: ZO SKIN HEALTH


Is Discontinued By Manufacturer ‏ : ‎ No


Language ‏ : ‎ English


Product Dimensions ‏ : ‎ 1.57 x 1.57 x 5.12 inches; 1.8 ounces


Item model number ‏ : ‎ ZOSH003-BR


UPC ‏ :


Manufacturer ‏ : ‎ ZO SKIN HEALTH


Frequently asked questions

If you place your order now, the estimated arrival date for this product is: Tuesday, May 20

Yes, absolutely! You may return this product for a full refund within 30 days of receiving it.

To initiate a return, please visit our Returns Center.

View our full returns policy here.

  • Klarna Financing
  • Affirm Pay in 4
  • Affirm Financing
  • Afterpay Financing
  • PayTomorrow Financing
  • Financing through Apple Pay
Leasing options through Acima may also be available during checkout.

Learn more about financing & leasing here.

Top Amazon Reviews


  • Wow!
Size: 1.7 Fl Oz (Pack of 1)
Excellent product! Worth the money because you only need a small amount. As my skin is changing with age, this product provides hydration that makes my skin feel young! I love that I don't have to go to a med spa to purchase.
Reviewed in the United States on January 29, 2025 by Heather

  • My Skin Has Never Looked Better – Total Game Changer!
Size: 1.7 Fl Oz (Pack of 1)
I’ve tried a lot of skincare products over the years, but this one truly stands out. From the first few uses, I noticed my skin looking smoother, more hydrated, and just overall healthier. The formula feels luxurious but absorbs quickly—no greasiness, no weird residue—just soft, glowing skin. What really sold me are the ingredients. The combination of Ultrasomes and Roxisomes is genius—those enzymes actually support the skin’s natural repair process, which is something I didn’t even realize my routine was missing. Add in Vitamin E for antioxidant protection and Ceramide 6 to strengthen the skin barrier? Yes, please. And I LOVE that it contains Matrixyl 3000—my skin feels firmer and more plump since I started using it. It’s only been a few weeks, but the difference is already noticeable. Fine lines are softer, and my skin tone looks more even. Even makeup goes on more smoothly now. I’ll definitely be repurchasing! Highly recommend if you’re serious about taking your skincare to the next level. A little goes a long way, and the 1.7 oz bottle is well worth it. ... show more
Reviewed in the United States on April 16, 2025 by Chris & Cassidy

  • Does the job!
Size: 1 Fl Oz (Pack of 1)
Love this product. Unfortunately, instead of Zo Skin Health Daily Power Defense, I received Aveeno Skin Cream. Am returning the Aveeno and have requested the correct product be sent. Hoping I will receive what I originally ordered (Skin Health Daily Power Defense) in the next delivery.
Reviewed in the United States on December 17, 2024 by MMB

  • Product good, packaging not.
Size: 1.7 Fl Oz (Pack of 1)
The product is great, always. But for some reason, there was NO dunnage at all in the box, which was as large as a shoebox. So the small ZO box was loose and probably flying all over the place on its trip from sender to buyer. And unfortunately, the tube which the product exits from was broken. So, now I have to reinsert and hold the tiny tube when I depress the the top. Otherwise, it squirts out down into the groove. Even when I hold it, it's still a mess. Again, it's always a great product, and this has never happened before. But why wouldn't you package an expensive product more safely? ... show more
Reviewed in the United States on July 11, 2024 by Jaelpa

  • Great Product
I’ve been using this product for years and this price is better than most places
Reviewed in the United States on December 5, 2024 by GAIL RIDDELL

  • Holy Grail of Skincare
I love all of the ZO products, but especially the Daily Defense! I apply it as the last step (besides sunscreen) in my AM routine and it keeps my skin moisturized without being too heavy. I found this product on Amazon cheaper than the first time I bought it at a local med spa. I'll definitely be looking here first before I restock on my other skincare products! ... show more
Reviewed in the United States on March 17, 2024 by Kaylee Raymer

  • Something is off
Packaged was damaged when I received it. Outside and inside of box have been tampered with. Lotion smells like something over the counter. It is thicker consistency than ZO daily defense purchased from an esthetics business. After I purchased it, I am seeing that the return policy provides zero protection. I hadn’t read the reviews until now, and I am regretting the purchase. ... show more
Reviewed in the United States on January 22, 2024 by Amie J Hale Amie J Hale

  • Love this stuff!
Size: 0.5 Fl Oz (Pack of 1)
Great product! Amazing for your dry skin!
Reviewed in the United States on August 31, 2024 by Robyn

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