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THORNE - Basic B-Complex - Tissue-Ready Vitamin B Complex Supplement with Choline - Supports Cellular Energy Production, Brain Health & Red Blood Cell Formation* - Gluten-Free - 60 Servings

  • Based on 4,056 reviews
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Features

  • Complete Formula: Each capsule provides a balance of 8 water-soluble B vitamins (B1, B2, B3, B5, B6, B7, B9, and B12) plus choline in their active, tissue-ready forms to enhance bioavailability in the body*
  • Cellular Energy: B vitamins support the conversion of carbohydrates into fuel for the body, as well as the metabolism of fats and proteins, to enhance cellular energy production and healthy red blood cell formation*
  • Cognitive Health: Supports an optimally functioning nervous system, a healthy brain, and nerve cells by serving as enzymatic cofactors to help make numerous brain neurotransmitters and support a healthy mindset*
  • 4 Rounds of Testing: Our state-of-the-art laboratories enable us to conduct 4 rounds of testing on every product, from analyzing the purity of raw materials to confirming the shelf life of finished formulas
  • Trusted: Thorne is chosen by champions and trusted by 100+ professional sports teams, a proud partner of U.S. National Teams, and the #1 recommended clinical brand by health-care practitioners (2023 Health-Care Practitioner Seller Survey)

Brand: THORNE


Item Form: Capsule


Primary Supplement Type: B-Complex, Choline


Diet Type: Gluten Free


Flavor: Unflavored


Is Discontinued By Manufacturer ‏ : ‎ No


Product Dimensions ‏ : ‎ 2.09 x 2.09 x 3.72 inches; 2.4 ounces


Item model number ‏ : ‎ B104


Date First Available ‏ : ‎ October 2, 2001


Manufacturer ‏ : ‎ Thorne Research


Best Sellers Rank: #1,795 in Health & Household (See Top 100 in Health & Household) #5 in Vitamin B-Complex Supplements #152 in Diet & Sports Nutrition


#5 in Vitamin B-Complex Supplements:


#152 in Diet & Sports Nutrition:


Customer Reviews: 4.7 4.7 out of 5 stars (4,104)


Frequently asked questions

If you place your order now, the estimated arrival date for this product is: Tuesday, Dec 23

This item is non-returnable:

Non-returnable due to Food safety reasons

View our full returns policy here.

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Top Amazon Reviews


  • Improved vitamin levels
I had a B deficiency on one round of labs, and we determined the supplement I had been taking just wasn’t cutting it. These vitamins seem to absorb much better, and also have the FULL B complex, not just certain ones. Not only are my levels back up, but they are high enough that I’m having to take this supplement less frequently. Thorne makes good and reliable products, from my experience. ... show more
Reviewed in the United States on November 18, 2025 by BusyLady16

  • One of the Best Formulas For MTHFR - Also, Here's Some Other Tips:
Updated as of 10/10/2022: I have known that I have the MTHFR gene mutation for about 12 years now. Even after diagnosis, I was using a few other B-complexes which I though were o.k. for my condition, but I did not realize that the B6 was not methylated. Turns out B6 has to be in the form of Pyridoxal 5-Phosphate, NOT Pyroxidine, to be more bioavailable to those who have MTHFR and do not methylate properly. I never knew that until about 5 years ago; the doctor I tested with didn't explain that part. After this discovery, I researched various B-complex formulas, and picked this one. I also wanted a B-complex that had methylated folic acid and that did not have a super high dose of methylcobalamin (B12), since my blood was testing high for B12 already. This formula fit the bill very well. A few other tips: 1) The amount of methylated folic acid per capsule here is low (400mcg). If you only take one capsule per day, I would also recommend taking additional methyl-folate if you do not methylate. However, please first discuss with your chosen physician, if possible. 2) If you take B6 in its methylated form of Pyridoxal 5-Phosphate (a.k.a. P5P), you also need to take magnesium so that the P5P pathway will work properly. .Without at least some magnesium to work with, you may end up feeling tired and with lower energy, which is probably not what you want. 3) B6 - along with certain co-factors like magnesium, zinc, vitamin-C, and folate, is necessary for the production of certain neurotransmitters like GABA and norepinephrine, as well as for the conversion of tryptophan or 5-HTP into serotonin. So you may want to consider taking some of these additional co-factors to enhance your results with this product (only folate is included in this product, you would have to buy the rest separately). Also note: Tyrosine is also required for the synthesis of dopamine, but I have not tried taking that yet. I believe I have been low in neurotransmitter production, and my nervous system has been a mess, due to a 12-year highly stressful job and the resulting sky-high cortisol levels (Thankfully, I am no longer at that job!). It's been getting better slowly now.....it takes time and it's also very helpful to decrease your sugar and simple carb intake (e.g. white flour). 4) B6 and zinc are both needed for the production of pancreatic enzymes and hydrochloric acid, so if you have low stomach acid / poor digestion, this may help. (Zinc is not included in this formula but you may wish to add it if you are looking to help your production of digestive enzymes) In summary, this formula really helps with all the above, and it may help you too. Douglas Labs also makes a similar formula although it has some variation in it's mix. Best wishes to you. Addendum, additional updates since 2017: I had started taking this Thorne Basic B once a day plus an additional 50mg -100mg of P5P back in 2017-2018. Sometimes I would miss a day of both, I'm not perfect :). Eventually I got more disciplined and was taking the Basic B twice a day. I felt that was working better for me. Overall I can say for sure that the combo has helped to calm down my nervous system. I even went through some serious surgeries and medical procedures (extremely stressful) in 2017 and 2018, and in the past I would be a nervous wreck 24/7 and would not be able to calm down. However, I no longer get that uncontrollable anxiety anymore, although there can be some days where I can still fall into a depressive state. Magnesium powder or capsules have also helped keep me calmer (at bedtime), and I have taken some Skullcap, Ashwagandha, and/or Passionflower at times to further calm myself down as needed. Since 2018 I have also tried other methylated B-complex formulas like MethylPro, Douglas Labs, Pure Encapsulations, Nordic Naturals, and Metabolic Maintenance - just to experiment. However I keep returning to this one because it seems to work the best for my physiology. Together with the P5P, this has been like a lifeline for me. I hope it can work for you too if you decide to try it. ... show more
Reviewed in the United States on June 25, 2017 by Banyon G.

  • High quality
Good stuff. Everyone should be on a good B complex and vitamin D.
Reviewed in the United States on December 6, 2025 by Jubilee B. Estes

  • Reliable B complex for daily energy and stress support
I really like this Thorne Basic B Complex as a straightforward daily B supplement. I personally take it to support overall energy, stress resilience and a healthy nervous system, and I do feel generally better and more “even” on days I take it. It also seems to help my nail strength over time. The formula uses active forms like methylfolate and methylcobalamin, which I look for, and the ingredient list is clean with no sugar or unnecessary fillers. The capsule is a manageable size and easy to swallow, with no real taste or aftertaste. For the quality of the forms and doses you get, I think it’s good value for money, and overall it feels like a solid, well-formulated B complex from a brand I trust. ... show more
Reviewed in the United States on December 2, 2025 by S.Foxy - Real Reviews S.Foxy - Real Reviews

  • Effective supplement
Gives me energy - I’ve tried other B complex before and never notice a difference. The capsules develop an odor unless you keep them in the fridge.
Reviewed in the United States on July 20, 2025 by Hoosier Gal

  • Healthy choice
Good product
Reviewed in the United States on November 18, 2025 by Shame

  • Great product
I take this brand for about 1 year. Great product.
Reviewed in the United States on December 1, 2025 by Claudia

  • Great
I can’t believe how much adding this has helped. I have more sustained energy, My hair skin and nails have also been the healthiest theyve ever been!
Reviewed in the United States on November 12, 2025 by Allison Hart

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