NOW Foods Supplements, UC-II Type II Collagen with Undenatured Type II Collagen, 120 Veg Capsules
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Tuesday, May 19
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Size: 120 Count (Pack of 1)
Pattern Name: Nutritional Supplement
Features
- WITH UNDENATURED TYPE II COLLAGEN: Derived from chicken sternum cartilage, UC-II is a patented form of collagen with undenatured (native) type II collagen that works with the immune system to support healthy joints.* Human clinical studies have found that just one 40 mg capsule of UC-II per day ca
- PROMOTES HEALTHY JOINT COMFORT AND FUNCTION*: Cartilage is one of the primary connective tissues of the body, providing flexibility and support to joints. Undenatured type II collagen is the principal structural protein in cartilage that is responsible for its tensile strength and toughness*
- CERTIFICATIONS/CLASSIFICATIONS: Non-GMO, Soy Free, Dairy Free, Egg Free, Made without Gluten, Nut Free, Sugar Free
- GMP Quality Assured: NPA A-rated GMP certification means that every aspect of the NOW manufacturing process has been examined, including our laboratory/testing methods (for stability, potency, and product formulation)
- Founded in 1968 by Elwood Richard, NOW is one of the largest independent, family- and employee-owned manufacturers of natural products
Description
Cartilage is one of the primary connective tissues of the body, providing flexibility and support to joints. Undenatured type II collagen is the principal structural protein in cartilage that is responsible for its tensile strength and toughness. Derived from chicken sternum cartilage, UC-II is a patented form of collagen with undenatured (native) type II collagen that works with the immune system to support healthy joints. Human clinical studies have found that just one 40 mg capsule of UC-II per day can help to promote joint comfort, as well as healthy joint function and flexibility. UC-II brand collagen with undenatured type II collagen (U.S. Patents 7,846,487, 7,083,820, 9,066,926 and EPO Patent EP1435906B1; Canadian patent CA 2459981C; and Japanese Patent JP 4800574B2). UC-II and logo are InterHealth N. I. trademarks. Aquamin is a registered trademark of Marigot Limited. Natural color variation may occur in this product.
Is Discontinued By Manufacturer ‏ : ‎ No
Product Dimensions ‏ : ‎ 1.95 x 1.95 x 4.3 inches; 2.96 ounces
Item model number ‏ : ‎ 3136
Date First Available ‏ : ‎ July 31, 2015
Manufacturer ‏ : ‎ NOW Sports - Nutrition and Wellness
Best Sellers Rank: #6,107 in Health & Household (See Top 100 in Health & Household) #158 in Blended Vitamin & Mineral Supplements #749 in Sales & Deals
#158 in Blended Vitamin & Mineral Supplements:
#749 in Sales & Deals:
Customer Reviews: 4.6 4.6 out of 5 stars (3,993)
Brand Name: NOW Foods
Primary Supplement Type: protein
Item Form: Capsule
Diet Type: Gluten Free
Product Benefits: Bone & Joint Support
Age Range Description: Adult
Container Type: Bottle
Dosage Form: Capsule
Model Name: UC-II Type II Collagen with Undenatured
UPC: 733739031365
Manufacturer: NOW Sports - Nutrition and Wellness
Manufacturer Part Number: 3136
Model Number: 3136
Unit Count: 120 Count
Item Weight: 2.96 ounces
Item Dimensions: 1.95 x 1.95 x 4.3 inches
Number of Items: 1
Total Servings Per Container: 120
Flavor: Unflavored
Material Features: Dairy Free, Egg Free, GMO Free, Gluten Free, Kosher Certified, Nut Free, Sugar Free
Specific Uses For Product: Joint Health
Allergen Information: Dairy Free, Egg Free, Non-GMO, Nut Free, Soy Free
Color: Off White W/Speckles
Frequently asked questions
If you place your order now, the estimated arrival date for this product is:
Tuesday, May 19
This item is non-returnable:
Non-returnable due to Food safety reasons
View our full returns policy here.
Non-returnable due to Food safety reasons
View our full returns policy here.
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Top Amazon Reviews
Size: 60 Count (Pack of 1)
Pattern Name: Nutritional Supplement
This product has been an absolute game changer for my 9year old golden retriever. she has elbow dysplasia and has had overall issues with her joints as she is a senior pup now. I wish i had started her on this sooner. i have tried other supplements for her, Wuffes, etc but NONE have been as effective as this. And we are not even done with the first bottle and already see results. The bottle recommends one tablet before bed on an empty stomach so thats what we do. WE both take one before bed. i administer the capsule with a bit of cocounut oil and she takes it easily. This product was recommended on dr judy morgan's naturally healthy pets website and it has been an amazing product. I also take it and have less joint pain. She was able to go for a mile walk yesterday after not being able to do so for 6 months or so. Amazing.
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Reviewed in the United States on February 12, 2026 by BigBoss
Size: 60 Count (Pack of 1)
Pattern Name: Nutritional Supplement
Very good product if it has an effect to deflate the knees.
Reviewed in the United States on March 26, 2026 by Sandy Galviz
Size: 60 Count (Pack of 1)
Pattern Name: Nutritional Supplement
It has helped with my right knee pain almost gone taken it at night on an empty stomach very impressed. I didn't know this worked on dogs too lol maybe vets should consider it also? 🤣
Reviewed in the United States on March 17, 2026 by Larry McCune
Size: 60 Count (Pack of 1)
Pattern Name: Nutritional Supplement
03/10/16... NOTE... they are no longer delivering the product described on this web page. On my last order (just received this week), I received this product... Now Foods UC-2 Collagen Veg Capsules, 40 mg, 120 Count ITS NOT THE SAME PRODUCT. Compare the Supplement Labels (on the back of both bottles). The only ingredient that matters is the "undenatured Type-II Collagen". All the other ingredients (including the standard chicken collagen) are of little value. You only want the product that delivers at least "10 mg of undenatured type-II collagen" but this new product delivers LESS-THAN the 10mg of the "undenatured" product (read the label). They dont state the actual amount anymore and, since that is the only ingredient that matters, you will be purchasing a product that is not up to the standard for joint support that you will hope to receive from the product. In other words, if you cant be sure that you will receive a product with "10mg of undenatured Type-II collagen", you might want to look at another sellers products (always review the Supplement Label to be sure you are getting at least the 10mg of undenatured type-II collagen... thats what you are paying for). I returned my order and bought a different sellers product. ----------------------------------------------------------------------------------------------------------- Original Review... My doctor had me on 1000MG of Nabumetone for Osteoarthritis in both hips. The Nabumetone was very effective and i went from walking back to jogging (which i've done all my life) in less than one week. Its a very effective and very inexpensive Med that really made a huge difference in my life but it does have that one problem (like so many other comparable meds), its an NSAID. There are issues with NSAID's and if there is way to avoid them, its to your benefit to do it. I tried glucosamine and chondroitin in various quantities and mixtures but they were largely ineffective against Osteoarthritis (and incomparable to the Nabumetone). Ibuprofen, Aleve and all the rest have the same or similar possible side effects so i kept looking for a better treatment. I read an article in a LifeExtension magazine about UC-II and decided to research it further. I read this article: [...] and that convinced me to try it. I can say without reservation that this product works!. It is far more effective than any OTC med and it is almost as good as the Nabumetone. Its a little more expensive than nabumetone but within 10 days of taking it, i was completely off the nabumetone. Thats a big victory to drop an NSAID for a more natural product. I don't know for how long the UC-II will remain effective but I don't want to have to go through more than one hip replacement procedure in my lifetime so im hoping i can get a few more years out of my hips before i have to rip them out for implants. I've been taking the UC-II (1 cap per day) for 9 months now and it is still working just fine so im pretty confident i wont need the new hips for a while. I cant say enough about this product other than to say if you have arthritis pain, you have nothing to lose by trying UC-II. Read the article i referenced (above) if you want more information.
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Reviewed in the United States on March 8, 2013 by not4nuthin
Size: 60 Count (Pack of 1)
Pattern Name: Nutritional Supplement
I am almost through my 1st bottle and this seems to be helping a little. I did find it odd that there is such a wide range of results in the reviews though. So after giving it some thought I came up with a couple of possibilities. Feel free to add in your opinions as to whether these might have influence on the effectiveness of this supplement in helping out our joints. 1. The directions say to take on an empty stomach. Well 1st thing is to know exactly when your stomach is empty. This varies person to person and for many supplements is more of a recommendation than a requirement. I know that if I eat a big dinner, my stomach still has food in it even 3 or 4 hours later when going to bed. Also, once I discovered why an empty stomach important for collagen I realized this could really influence its effectiveness. Collagen supposedly is destroyed by digestive enzymes. It needs to pass through your stomach intact into the small intestine. So having your stomach empty helps this happen. Also, for the same reason, you probably need to wait a while after taking the capsule before eating or drinking anything other than water in order to avoid digestive enzymes being stimulated. I have started taking mine if I wake up in the middle of the night. If I sleep through the night, I take it first thing in the morning and wait an hour or two before eating anything. 2. Many of us with joint pain take a NSAID like Aleve or Ibuprofen. I just learned that NSAIDs are collagen inhibitors. This is from The National Institute of Health: Research Paper Title -"The effects of NSAID on the matrix of human articular cartilages." A quote from the paper - "When the relative metabolic (synthetic/repair activity) of these human cartilages was compared, it was demonstrated that in osteoarthritis (OA) and rheumatoid arthritis (RA) cartilages synthetic activity was diminished by approximately 50%". So all this time I have been taking the collagen, maybe by also taking one Aleve every morning, I have been lessening the effectiveness of the collagen? I am about to start my 2nd bottle and will stop with the Aleve. (I'll use Tylenol if needed) I will see if I notice even more improvement. I would be interested in hearing other ideas on these two points. I have looked into this enough to be pretty confident these are two important things to account for in taking the collagen. However I may have overlooked something and would certainly want to hear about it if I have. Thanks! I also found the following lengthy summary of another study on the same topic. I do wonder about this though since the number one doctor recommendation for arthritis seems to be NSAID. I guess the normal caveat applies: "Talk to your doctor before changing anything"? RECOMMENDATIONS ON THE USE OF NSAIDS IN OSTEOARTHRITIS The preponderance of scientific evidence shows that NSAIDs damage articular cartilage. Various scientific papers and consensus groups have stated that there is no convincing data to show that the widely used NSAIDs and recommended selective COX-2 inhibitors have favorable effects on cartilage.129-131 Even the main consensus paper from the International Cartilage Repair Society and Osteoarthritis Research Society International stated that NSAID use has to be limited to the short term. Specifically the recommendation was as follows: In patients with symptomatic hip or knee osteoarthritis, non-steroidal anti-inflammatory drugs (NSAIDs) should be used at the lowest effective dose but their long-term use should be avoided if possible.132 They also noted that NSAIDs should not be first-line therapy for joint OA. Other groups have raised similar sentiments. The committees of the International League Against Rheumatism and the World Health Organization came up with guidelines for the testing of new drugs in osteoarthritis. The consensus from these meetings resulted in recommendations by The European Group for the Respect of Ethics and Excellence in Science (GREES) for governmental registration and approval of new drugs used in the treatment of OA and have added the requirement that the drug not have a deleterious effect on the diseased and non-diseased contra lateral joint; i.e., no deleterious effect on osteoarthritic or normal cartilage.133 If this latter recommendation were followed, the vast majority, if not all NSAIDs, would be immediately taken off the market and no new ones would get approved. While it is admirable for the various consensus and rheumatology organizations to educate doctors and the lay public about the necessity to limit NSAID use in OA, this author (RH) feels the warnings are not enough. Within the last year, for instance, the FDA has again implemented new rules requiring stronger and more extensive label warnings (in addition to the heart disease risks) regarding the risk of liver damage and stomach bleeding for people taking common over-the-counter pain relievers. As for NSAIDs, the new regulations require front labels to instruct users to see new warnings that say, “This product contains a nonsteroidal anti-inflammatory drug (NSAID), which may cause severe stomach bleeding. The chance is higher if you are age 60 or older, have had stomach ulcers or bleeding problems, take a blood thinning or steroid drug, take other drugs containing prescription or nonprescription NSAIDs, have three or more alcoholic drinks every day using this product, take more or for a longer time than directed.”134 The lay public for whom NSAIDs are prescribed and recommended by both health care professionals and drug manufacturers should be aware that long-term NSAID use is detrimental to articular cartilage. Specifically, be informed that NSAIDs will likely worsen the OA disease for which it is prescribed. Physicians, allied health care professionals, and drug manufacturers should be required to inform the lay public that NSAID use can accelerate OA articular cartilage degeneration. A strict warning label on these medications should read as follows: The use of this nonsteroidal anti-inflammatory medication has been shown in scientific studies to accelerate the articular cartilage breakdown in osteoarthritis. Use of this product poses a significant risk in accelerating osteoarthritis joint breakdown. Anyone using this product for the the pain of osteoarthritis should be under a doctor’s care and use of this product should be with the very lowest dose and for the shortest possible duration of time. One of the basic tenants of medicine is stated in the Hippocratic oath, “I will prescribe regimens for the good of my patients according to my ability and my judgment and never do harm to anyone.”135 For doctors to uphold this statement in the treatment of their OA patients, it would necessitate the almost complete banning of the use of NSAIDs for this condition. If this does not occur, then most likely the exponential rise in degenerative arthritis and subsequent musculoskeletal surgeries, including knee and hip replacements, as well as spine surgeries, will continue for decades to come. - See more at: [...]
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Reviewed in the United States on April 30, 2016 by Will
Size: 120 Count (Pack of 1)
Pattern Name: Nutritional Supplement
I love this product! Easy to take and has really helped me with neck crepitus( creaking and cracking from collapsed disc) and my back pain has improved significantly from L5 collapsed disc. I agree with another reviewer that this should be taken on an empty stomach and I take 2 a day! No side effects whatsoever and well tolerated. I will continue to purchase this! I am 55 years old and have had terrible joint problems and it runs in my family. My Mother always stressed to take collagen type 2.. I am finally listening!
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Reviewed in the United States on September 20, 2025 by Leslie M.
Size: 120 Count (Pack of 1)
Pattern Name: Nutritional Supplement
Very good product as helps with my skin nails joint health .Small capsule - easy to swallow and gets absorbed.Will continue to buy this collagen supplement.
Reviewed in the United States on January 10, 2026 by Lizzie