Nioxin System 4 Scalp + Hair Thickening Shampoo | For Colored, Dry, & Damaged Hair with Progressed Thinning | Maintain Vibrant Color | Nourish & Boost Hair Density with Niacinamide & Biotin | 33.8 Fl Oz
Condition: New
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Availability:
In Stock.
Arrives
Thursday, Sep 4
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Brand: NIOXIN
Scent: Sandalwood
Item Weight: 2.3 Ounces
Item Form: Drop
Active Ingredients: Niacinamide, Caffeine, Lauric Acid, and Sandalore
Package Dimensions : 6.1 x 1.65 x 1.65 inches; 2.3 ounces
Item model number : 99350182438
Manufacturer : Nioxin
Best Sellers Rank: #11,747 in Beauty & Personal Care (See Top 100 in Beauty & Personal Care) #100 in Hair Regrowth Treatments
#100 in Hair Regrowth Treatments:
Customer Reviews: 4.1 4.1 out of 5 stars 672 ratings
Frequently asked questions
If you place your order now, the estimated arrival date for this product is:
Thursday, Sep 4
This item is non-returnable:
Non-returnable. Transportation of this item is subject to hazardous materials regulation
View our full returns policy here.
Non-returnable. Transportation of this item is subject to hazardous materials regulation
View our full returns policy here.
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Top Amazon Reviews
I've been using the Nioxin Hair Fall Defense Intensive Daily Leave-In Hair Treatment, and it has made a significant difference in my hair health. After consistent use, I've noticed a substantial reduction in hair fall and breakage. My hair feels thicker, stronger, and more resilient. The application is straightforward—just a few pumps massaged into the scalp daily. The formula is lightweight and doesn't leave any greasy residue, making it perfect for everyday use. The scent is mild and pleasant, which is a bonus. Overall, this treatment has exceeded my expectations. It's become an essential part of my hair care routine, and I highly recommend it to anyone struggling with hair thinning or loss.
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Reviewed in the United States on May 17, 2025 by The review QUEEN
I wanted to wait until 2 months after use before posting my honest review. I’ve been using Nioxin hair serum consistently for about 67 days. I apply it directly to my scalp (I part my hair into sections, then spray), I then use a scalp massager massaging my scalp for 3 minutes. I’ve been doing this twice a day. My hair is fairly healthy, but I’ve been having issues with shedding since summer. I have fine hair that’s low density. What I’ve experienced since I started using is little to no shedding- definitely shedding less than the normal 50-100 strands. In the 2 plus months I have about 2 inches of hair growth (I purchased one of those hair growth tracking tshirts). I find many serums/oils boast hair growth, but few talk about growth retention. My hair is stronger and most importantly thicker. Overall I love it and find it to be very effective! Now a very small minus is the smell which takes some getting used to. The product has a sandalwood smell which I am not a fan! What I did to “lessen” the smell is I apply 1-2 small sprays closely to my scalp then I spread the serum across my scalp using my finger- I don’t smell anything doing this. The serum doesn’t make your hair oily or greasy after applying. You can use sparingly (1-2 pumps) then use a scalp massager to spread it around. I purchased for 50 USD, but I feel like this will last me 4-5 months even applying twice a day. I don’t think it has protein in it which is great because I am protein sensitive and I find many of the popular hair oils contain protein. Overall it’s a great product and I will continue to use it.
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Reviewed in the United States on December 14, 2023 by G. Brown
4 stars because I think this really works just isn’t for me. I really wanted this product as it has so many positive reviews for its intended use which is retaining existing hair and cutting down on shedding. I have caffeine sensitivity and did see it was #4 ingredient in the label so I was concerned but I had no way to know if topical application would produce similar results as ingesting caffeine. Well, it did. After 45 minutes it produced a fast heart rate over 160 and adrenaline rush similar to if I had drank too much caffeine. If only lasted an hour versus 4 hours from ingesting. Just be aware if you have this problem but otherwise I hear it works great. Disappears into the hair with no residue and does not affect styling or cause buildup. Wish I could use!
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Reviewed in the United States on December 10, 2024 by Marianne Donato
I have been using this product consistently now for about 3 months, and I have to say I absolutely love it. My hair is definitely thicker and stronger than it was before. I am also very surprised at the people who are going on about the smell. It does have a scent, but it's a very clean & minty scent that I actually really like, and have received compliments on- so it's funny to me to see people saying the smell is horrible. I completely disagree. I will also say that I do not use this product alone. I use the Nioxin Night Density Rescue Serum, the Nioxin System 2 shampoo/conditioner kit, and I also take prescription Finasteride and Minoxidil. I have found that the best way to get amazing results is to do multiple things simultaneously that are proven to get results. Sure, I'm not exactly sure which of them is doing the most help, but I think together they all do the best job. Way to go, Nioxin!
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Reviewed in the United States on July 2, 2024 by Tyson Jones
I have been using Nioxin night density rescue serum for over a year and seeing some results, but I don't like how oily it makes my hair, so I decided to try this Nioxin hair fall defense serum when it went on sale due to the good reviews. Good news is it isn't oily, but I realized quickly that I should have listened to the not so good reviews. I am apparently one of the few sensitive to topical caffeine and also the sandalwood scent. The scent is overwhelming to me and lingers all day, giving me a headache, plus when I used it at night I had trouble sleeping, I assume due to the caffeine. So it's back to the other serum for me. BTW, the reason I'm using such products is due to very fine hair that has been thinning as I age, and then 2 cases of COVID in 2 years made it worse.
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Reviewed in the United States on January 4, 2025 by AZ Native
I don't know how well this product works because I simply could not get over its pungent fragrance. Gross. Listen, I love Nioxin. I've been an avid fan and daily user of its various leave-in products for years. YEARS. But, this is the first Nioxin product I had to throw out because it just smells SO BAD. The smell is not only pungent and strong, it's just straight-up bad. It smells like an incredibly offensive men's cologne - like cigars, tobacco, whiskey, smoke, and alcohol. It's so strong that it caused an eczema flare-up on my neck!! That was the final straw for me - if it hadn't triggered that eczema flare-up, I would've done my best to ignore the fragrance and I would've continued to use this product to test its effectiveness. But, after just three (3!!) uses, my neck became super red, itchy, scaly, and inflamed. Once I stopped using the product, my skin completely calmed down. I wanted to give Nioxin the benefit of the doubt so, after a long pause, I picked this up again. Bad idea. Alas, just three (3) uses in, once again, my eczema flared-up like crazy. This is definitely a NO-GO for me. Nioxin, can you PLEASE make this fragrance-free or with a lighter fragrance?!
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Reviewed in the United States on April 14, 2025 by Darkyetlovely