Search  for anything...

Neutrogena On-The-Spot Acne Spot Treatment Cream, 0.75 oz | 2.5% Benzoyl Peroxide, Gentle Blemish Medicine, Acne-Prone Skin, Vanishing Formula, Clinically Proven Day-1 Results

  • Based on 4,383 reviews
Condition: New
Checking for the best price...
$8.97 Why this price?
Save $1.87 was $10.84

Buy Now, Pay Later


As low as $2 / mo
  • – 4-month term
  • – No impact on credit to apply
  • – Instant approval decision
  • – Secure and straightforward checkout

Ready to go? Add this product to your cart and select a plan during checkout.

Payment plans are offered through our trusted finance partners Klarna, Affirm, Afterpay, Zip, Apple Pay, and Google Pay. No-credit-needed leasing options through Acima may also be available at checkout.

Learn more about financing & leasing here.

Selected Option

Free shipping on this product

FREE 30-day refund/replacement

To qualify for a full refund, items must be returned in their original, unused condition. If an item is returned in a used, damaged, or materially different state, you may be granted a partial refund.

To initiate a return, please visit our Returns Center.

View our full returns policy here.


Availability: In Stock.
Fulfilled by Amazon

Arrives Sunday, Aug 23
Order within 7 hours and 16 minutes
Available payment plans shown during checkout

Protection Plan Protect Your Purchase
Checking for protection plans...

Size: 0.75 Ounce (Pack of 1)


Features

  • Acne spot treatment: Targets pimples with gentle 2.5% benzoyl peroxide; Effectively treats breakouts without over-drying or irritating skin, making it ideal for daily use on acne-prone and dry skin types
  • Vanishing cream formula: Lightweight, fast-absorbing, and invisible on skin; This acne treatment for face delivers lasting results and can be used up to three times daily for clearer, healthier-looking skin
  • Clinically proven results: Clears skin starting day 1 without stinging or burning; Dermatologist-tested formula goes deep down into pores to kill the acne bacteria that can cause pimples
  • Gentle for dry and acne-prone skin: Perfect for those seeking effective acne care without over dry-ing or discomfort
  • Neutrogena On-The-Spot Acne Spot Treatment cream is an effective acne treatment for face in a convenient 0.75 oz tube

Description

Neutrogena On-The-Spot Acne Spot Treatment Cream with 2.5% benzoyl peroxide is a clinically proven acne spot treatment for face that helps clear breakouts fast without over-drying, stinging, or burning. This gentle vanishing cream formula absorbs quickly, works invisibly, and is designed for acne-prone and dry skin. The lightweight cream penetrates deep into pores to kill acne bacteria that cause pimples and helps prevent new ones from forming. Suitable for daily use, this acne treatment for face can be applied up to three times a day to affected are-as. The fast working formula helps maintain skin comfort while delivering effective results, making it an ideal choice for those seeking a gentle yet effective acne spot treatment. The 0.75 oz tube is perfect for targeted application and on-the-go use. This acne spot treatment cream is formulated to address the needs of those with acne- prone and dry skin, providing a vanishing cream that absorbs quickly and leaves no residue. The clinically proven formula is designed to be gentle enough for daily use, helping to reduce the appearance of pimples and helps prevent new breakouts. With its lightweight, non-greasy texture, this acne treatment for face fits seamlessly into your skincare routine. The vanishing cream formula ensures that the treatment works invisibly, so you can use it throughout the day without noticeable residue. Neutrogena On-The-Spot Acne Spot Treatment Cream is an essential addition to your personal care products, delivering targeted acne control and supporting your skin care goals. Trust in a product that combines the power of benzoyl peroxide with a gentle, cream base for effective, visible results. Brand Story By Neutrogena

Product Dimensions ‏ : ‎ 1.45 x 3.95 x 3.95 inches; 1.6 ounces


Item model number ‏ : ‎ 2620649002


UPC ‏ :


Manufacturer ‏ : ‎ Kenvue


Best Sellers Rank: #1,870 in Beauty & Personal Care (See Top 100 in Beauty & Personal Care) #56 in Facial Serums


#56 in Facial Serums:


Customer Reviews: 4.6 4.6 out of 5 stars (4,383)


Item Form: Cream


Scent Name: Unscented


Product Benefits: Hydrating


Skin Type: Dry


Special Ingredients: Benzoyl Peroxide


Target Use Body Part: Face


Active Ingredients: benzoyl_peroxide


Container Type: Tube


Brand Name: Neutrogena


Global Trade Identification Number: 06, 07


UPC: 070501017906


Manufacturer: Kenvue


Model Number: 2620649002


Manufacturer Part Number: PPAX1208410


Item Weight: 1.6 ounces


Item Volume: 1.6 fluid ounces


Size: 0.75 Ounce (Pack of 1)


Package Size Name: 0.75 Oz.


Material Features: Non-Comedogenic, Oil Free


Frequently asked questions

If you place your order now, the estimated arrival date for this product is: Sunday, Aug 23

Yes, absolutely! You may return this product for a full refund within 30 days of receiving it.

To initiate a return, please visit our Returns Center.

View our full returns policy here.

  • Klarna Financing
  • Affirm Pay in 4
  • Affirm Financing
  • Afterpay Financing
  • Zip Pay in 4
  • Financing through Apple Pay
  • Financing through Google Pay
Leasing options through Acima may also be available during checkout.

Learn more about financing & leasing here.

Top Amazon Reviews


  • Simple spot treatment that works
Size: 0.75 Ounce (Pack of 1)
This is a small tube, but it worked well on a pimple on my nose. I used a very small amount in the morning and before bed. It was easy to apply and did not irritate my skin. After about a week, the spot cleared up completely. It is simple, straightforward, and effective for occasional breakouts. You do not need much product, so the tube lasts a long time. Good basic acne treatment that does what it says. ... show more
Reviewed in the United States on June 26, 2026 by JoeK

  • Fast-acting spot treatment that really works
Size: 0.75 Ounce (Pack of 1)
This has been one of the most effective spot treatments I’ve used. A small amount goes a long way, and I noticed blemishes looking smaller and less red after just a couple of applications. It dries quickly, layers well under moisturizer, and doesn’t leave my skin feeling overly dry when used as directed. It’s a product I keep on hand for the occasional breakout, and it has consistently worked well for me. ... show more
Reviewed in the United States on July 1, 2026 by Sean Bozarth

  • gentle, works
Size: 0.75 Ounce (Pack of 1)
This is gentle and seems to help (gradually) with my budding pimples so that I didn't have to pimple patch some of them. It wasn't a miracle flatten pimples within a day thing for me (took probably at least 2 days for smaller ones and more for larger ones), but that works for me because my skin can tolerate it. It does dry your skin out a bit though so moisturizing is definitely necessary. ... show more
Reviewed in the United States on July 13, 2026 by someone

  • Works great
Size: 0.75 Ounce (Pack of 1)
I’ve been using this acne cream for a few weeks and I’m very happy with the results. It helped reduce redness and breakouts without drying out my skin too much. The texture is lightweight, absorbs quickly, and doesn’t leave a greasy feeling. My skin looks clearer and smoother, and new pimples seem to heal faster. I would definitely recommend it to anyone struggling with mild to moderate acne. ... show more
Reviewed in the United States on June 8, 2026 by Alina Demydko

  • Reasonably priced.
Size: 0.75 Ounce (Pack of 1)
Works well not harsh on skin. Takes longer to work compared to a higher concentration of benzoyl. With consistent use you see improvement.
Reviewed in the United States on May 31, 2026 by MSBrown

  • Neutrogena On-The-Spot Acne Treatment
Size: 0.75 Ounce (Pack of 1)
Works fast and effectively! It reduces redness overnight and helps prevent new breakouts. The cream absorbs quickly and doesn’t dry out my skin. A must-have for anyone managing acne.
Reviewed in the United States on June 24, 2026 by Amazon Customer

  • Great spot treatment
Size: 0.75 Ounce (Pack of 1)
This stuff works well on my breakouts. I use it mostly as a spot treatment on my highly sensitive face and I like it a lot. I’m hesitant to put things on my face but this is a product I will keep using. It seems to minimize my breakouts quickly without drying out my skin.
Reviewed in the United States on June 5, 2026 by Barbie

  • Amazing Neutrogena acne treatment
Size: 0.75 Ounce (Pack of 1)
Its really works on acne. Just one night as indicated the acne was so tiny i could see anything. The top product.
Reviewed in the United States on July 14, 2026 by Lou Francois

Can't find a product?

Find it on Amazon first, then paste the link below.
Checking for best price...