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Neutrogena On-The-Spot Acne Spot Treatment Cream with 2.5% Benzoyl Peroxide, Gentle Face Blemish Medicine for Acne-Prone Skin, Vanishing Formula, Clinically Proven Day-1 Results, 0.75-Ounce Tube

  • Based on 3,692 reviews
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Availability: In Stock.
Fulfilled by Amazon

Arrives Tuesday, Jun 2
Order within 13 hours and 10 minutes
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Size: 0.75 Ounce (Pack of 1)


Features

  • Acne spot treatment: Targets pimples with gentle 2.5% benzoyl peroxide; Effectively treats breakouts without over-drying or irritating skin, making it ideal for daily use on acne-prone and dry skin types
  • Vanishing cream formula: Lightweight, fast-absorbing, and invisible on skin; This acne treatment for face delivers lasting results and can be used up to three times daily for clearer, healthier-looking skin
  • Clinically proven results: Clears skin starting day 1 without stinging or burning; Dermatologist-tested formula goes deep down into pores to kill the acne bacteria that can cause pimples
  • Gentle for dry and acne-prone skin: Perfect for those seeking effective acne care without over dry-ing or discomfort
  • Neutrogena On-The-Spot Acne Spot Treatment cream is an effective acne treatment for face in a convenient 0.75 oz tube

Description

Neutrogena On-The-Spot Acne Spot Treatment Cream with 2.5% benzoyl peroxide is a clinically proven acne spot treatment for face that helps clear breakouts fast without over-drying, stinging, or burning. This gentle vanishing cream formula absorbs quickly, works invisibly, and is designed for acne-prone and dry skin. The lightweight cream penetrates deep into pores to kill acne bacteria that cause pimples and helps prevent new ones from forming. Suitable for daily use, this acne treatment for face can be applied up to three times a day to affected are-as. The fast working formula helps maintain skin comfort while delivering effective results, making it an ideal choice for those seeking a gentle yet effective acne spot treatment. The 0.75 oz tube is perfect for targeted application and on-the-go use. This acne spot treatment cream is formulated to address the needs of those with acne- prone and dry skin, providing a vanishing cream that absorbs quickly and leaves no residue. The clinically proven formula is designed to be gentle enough for daily use, helping to reduce the appearance of pimples and helps prevent new breakouts. With its lightweight, non-greasy texture, this acne treatment for face fits seamlessly into your skincare routine. The vanishing cream formula ensures that the treatment works invisibly, so you can use it throughout the day without noticeable residue. Neutrogena On-The-Spot Acne Spot Treatment Cream is an essential addition to your personal care products, delivering targeted acne control and supporting your skin care goals. Trust in a product that combines the power of benzoyl peroxide with a gentle, cream base for effective, visible results. Brand Story By Neutrogena

Is Discontinued By Manufacturer ‏ : ‎ Yes


Product Dimensions ‏ : ‎ 1.45 x 3.95 x 3.95 inches; 1.6 ounces


Item model number ‏ : ‎ 2620649002


UPC ‏ :


Manufacturer ‏ : ‎ Kenvue


Best Sellers Rank: #2,187 in Beauty & Personal Care (See Top 100 in Beauty & Personal Care) #69 in Facial Serums


#69 in Facial Serums:


Customer Reviews: 4.6 4.6 out of 5 stars (4,232)


Item Form: Cream


Scent Name: Unscented


Product Benefits: Hydrating


Skin Type: Dry


Special Ingredients: Benzoyl Peroxide


Target Use Body Part: Face


Active Ingredients: benzoyl_peroxide


Container Type: Tube


Brand Name: Neutrogena


Global Trade Identification Number: 06, 07


UPC: 070501017906


Manufacturer Part Number: PPAX1208410


Model Number: 2620649002


Manufacturer: Kenvue


Item Weight: 0.1 Pounds


Item Volume: 1.6 Fluid Ounces


Size: 0.75 Ounce (Pack of 1)


Package Size Name: 0.75 Oz.


Material Features: oil-free and non-comedogenic


Frequently asked questions

If you place your order now, the estimated arrival date for this product is: Tuesday, Jun 2

Yes, absolutely! You may return this product for a full refund within 30 days of receiving it.

To initiate a return, please visit our Returns Center.

View our full returns policy here.

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Top Amazon Reviews


  • Best spot treatment for the occasional pimple!
Size: 0.75 Ounce (Pack of 1)
This is the best acne spot treatment I’ve ever used. I always keep a fresh tube on hand. It works quickly and the 2.5% benzoyl peroxide is effective but a lot gentler than most acne products. The tube is designed with a small opening which is great for dispensing only the tiny amount needed to spot treat. Follow directions, be patient and you’ll be very satisfied with the results. ... show more
Reviewed in the United States on May 8, 2026 by Vivian SB

  • Works great
Size: 0.75 Ounce (Pack of 1)
Works great I get a zit once in a great while I just put it on like it says. Gets rid of zit fast I would buy again love this stuf
Reviewed in the United States on May 25, 2026 by Nancy Gilbert

  • Great stuff. Not harsh and very effective.
Size: 0.75 Ounce (Pack of 1)
This stuff is pretty darn amazing on pimples and limited breakouts. What I have found is....I'm too damn old to be getting pimples. Thanks, peri-menopause. But, if I wake up and my skin has decided to pull this nonsense on me, I simply dab some on-the-spot, on that spot. By evening, I may need a second dab but, in no time, the pimple has dried and all-but disappeared and what I find remains is typically, a dot of dry skin where a pimple once was. Wash that off with your face washing habit and, viola. No more pimple in short order. My youngest child uses it as well, with similar, efficient results. Great stuff and not at all harsh, in our experience. We love it. ... show more
Reviewed in the United States on March 9, 2026 by Sarah Wood

  • Leaves skin dry
Size: 0.75 Ounce (Pack of 1)
Great acne cream. It works to get rid of acne, but leaves skin very dry.
Reviewed in the United States on April 29, 2026 by Winnie

  • Neutrogena recommend Neutrogena recommend
Size: 0.75 Ounce (Pack of 1)
Neutrogena On-The-Spot Acne Spot Treatment Cream with 2.5% Benzoyl Peroxide, Gentle Face Blemish Medicine for Acne-Prone Skin, Vanishing Formula, Clinically Proven Day-1 Results, 0.75-Ounce Tube I’ve been using this On-the-Spot acne treatment from Neutrogena for a while now, and I’m really impressed with the results. The cream is thin and easy to apply, and it absorbs quickly without leaving my skin greasy. I’m already used to using it, and I’ve honestly never been disappointed any day I apply it on any small imperfection I have. It helps dry out pimples fast while still being gentle on my skin. A small amount goes a long way, and I would definitely recommend it to anyone dealing with breakout☺️ ... show more
Reviewed in the United States on February 16, 2026 Reviewed in the United States on February 16, 2026 by Kate Cyrise

  • Yes, it really works
Size: 0.75 Ounce (Pack of 1)
It actually works. Just be careful with opening it to not get any on your hands. I used a pimple patch before this that did absolutely nothing. This worked almost instantly. I don’t get pimples very often but when I do it’s a single stubborn one. This product took it out and back home to where it came from. Just dab a small amount on the pimple using a Q-tip and you won’t regret it. ... show more
Reviewed in the United States on May 7, 2026 by It's a good one

  • YUP YUP
Size: 0.75 Ounce (Pack of 1)
OMG I LOVE! Will never go without. Really does help those stubborn pimples go away. I can't show up to work with pimple patches on my face so I bought this product, it has been amazing. Deff worth it.
Reviewed in the United States on May 20, 2026 by RJ

  • Best acne treatment I've ever used!
Size: 0.75 Ounce (Pack of 1)
I spent $50 bucks on Il Makiage foundation after seeing countless reviews from many many people. Once I got it I used it 2x only to have my face breakout into blister like eruptions and splotches. I was mortified. Then I remembered how a long time ago I used this treatment for acne. Just like it did before it worked like a charm!! I am so so happy I remembered this product. It took 3 days and my face was completely cleared and back to normal. No stinging, no burning and no odor. It is DEFINITELY a product you want in your medicine cabinet or drawer. Could not be more relieved! ... show more
Reviewed in the United States on April 1, 2026 by Tina

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