Search  for anything...

NEOCUTIS Bio Cream Firm - Smoothing and Tightening, Anti-Aging Cream - Firming, Hydrating and Soothing - for Fine Lines, Wrinkles and Improving Skin Tone and Texture - Skin Healing - 50 ml / 1.69 fl

  • Based on 182 reviews
Condition: New
Checking for the best price...
$188.00 Why this price?

Buy Now, Pay Later


As low as $31.33 / mo
  • – 6-month term
  • – No impact on credit to apply
  • – Instant approval decision
  • – Secure and straightforward checkout

Ready to go? Add this product to your cart and select a plan during checkout.

Payment plans are offered through our trusted finance partners Klarna, Affirm, Afterpay, Apple Pay, and PayTomorrow. No-credit-needed leasing options through Acima may also be available at checkout.

Learn more about financing & leasing here.

Free shipping on this product

FREE 30-day refund/replacement

To qualify for a full refund, items must be returned in their original, unused condition. If an item is returned in a used, damaged, or materially different state, you may be granted a partial refund.

To initiate a return, please visit our Returns Center.

View our full returns policy here.


Availability: In Stock.
Fulfilled by Amazon

Arrives Monday, Jul 13
Order within 13 hours and 10 minutes
Available payment plans shown during checkout

Protection Plan Protect Your Purchase
Checking for protection plans...

Features

  • Preserve with Growth Factors. See visible improvement in the look of fine lines and wrinkles with intensely revitalizing proprietary peptides. These proprietary peptides help skin look firmer and feel tighter with continued use.
  • Smooth and Tone. The included Niacinamide and Argan Kernel Oil help to improve skin tone and texture while calming acne, enhancing the feel of skin smoothness.
  • Rich Hydration. This luxury cream increases skin hydration for enhanced skin smoothness and stunning luminosity. The deeply nourishing oils moisturize skin to promote a more refined tone and texture.
  • Replenish Healing Skin. Neocutis Bio Cream Firm helps support healing skin after cosmetic or dermatological treatments such as dermaplaning and microdermabrasion.
  • How to Use. Apply in the morning and/or evening to the face, neck and decollete, or as directed by your skincare professional. If used during the day, add a broad-spectrum sunscreen like ReACTIVE+*, JOURNEE or MICRO DAY.

Description

Neo Cleanse Hyalis+ Lumiere Firm Bio Cream Firm RéACTIVE+ Over 15 years ago, NEOCUTIS was founded on the basis of extensive wound-healing research. Their wound healing technology was found to help heal skin making it appear healthier. NEOCUTIS scientists began to explore how to apply the same principles to improve the appearance of aging skin. And they accomplished just that! NEOCUTIS’s ongoing, cutting-edge research and meticulous craftsmanship delivers targeted skincare to help nourish and rejuvenate skin. Visit the Store NEOCUTIS’s Lumiere Firm Riche was the winner of the Marie Claire: Favorite for Mature Skin Award (2023)! This collection of anti-aging products is proven to rejuvenate and help improve the appearance of skin. Visit the Store NEOCUTIS’s NeoCleanse Gentle Cleanser was the winner of InStyle’s Best Cleanser for Dry and Sensitive Skin Beauty Award (2023)! Formulated with proprietary peptides, this face cream decreases signs of aging including uneven tone, wrinkles, and sagginess. This award-winning eye cream targets the delicate eye area to reduce the appearance of crow’s feet, puffiness, and under-eye darkness. This luxury serum minimizes the appearance of wrinkles, refines texture, brightens skin tone, and boosts elasticity and hydration. NEOCUTIS products are formulated for all skin types including normal, dry, oily, and combination skin. We recommend consulting your provider to learn which NEOCUTIS products are best for your skin type. No. NEOCUTIS products are formulated for skin tolerability. The skin tolerability of these products was evaluated during standard dermatological studies for cosmetic products. Speak with your healthcare provider regarding what products are safe for your skin. Based on Bio Cream, the original anti-aging, growth-factor formulation, this new combination treatment also contains our proprietary peptides. A: Based on Bio Cream, the original anti-aging, growth-factor formulation, this new combination formulation also contains our proprietary peptides. A: Bio Gel Firm is an evolution of Bio Gel, our anti-aging, growth-factor formulation, now paired with proprietary peptides to additionally support collagen and elastin. New Bio Cream Firm integrates growth factors with proprietary peptides in one effective formulation. Bio Cream Firm also contains argan oil. In a consumer perception study, users expressed high satisfaction with results after both 14 and 30 days of twice-daily use. Yes. NEOCUTIS does not test our products on animals. NEOCUTIS skincare is dermatologist-tested, non-comedogenic, and free of color additives or fragrance.

Product Dimensions ‏ : ‎ 1.4 x 1.4 x 6.6 inches; 1.6 ounces


UPC ‏ :


Best Sellers Rank: #49,058 in Beauty & Personal Care (See Top 100 in Beauty & Personal Care) #1,256 in Face Moisturizers


#1,256 in Face Moisturizers:


Customer Reviews: 4.6 4.6 out of 5 stars (182)


Brand Name: NEOCUTIS


Age Range Description: Adult


Skin Type: Combination, Normal, Oily


Number of Items: 1


Item Form: Cream


Target Use Body Part: Face


Product Benefits: Firming


Specific Uses For Product: Apply in the evening to the face, neck and décolleté, or as directed by your skincare professional.


Country as Labeled: United States


Recommended Uses For Product: Fine Lines and Wrinkles, Skin Discoloration, Sagginess, Redness


UPC: 810235030075


Global Trade Identification Number: 75


Item Type Name: Face Cream


Item Volume: 50 Milliliters


Item Dimensions: 1.4 x 1.4 x 6.6 inches


Unit Count: 1.00 Fluid Ounces


Item Weight: 1.6 ounces


Active Ingredients: peptides


Special Ingredients: Growth Factors, Proprietary Peptides, Glycerin, Argan Oil, Borage seed Oil


Material Type Free: Paraben Free


Other Special Features of the Product: Addresses signs of aging including uneven tone and texture, wrinkles, and sagginess.


Scent Name: Fragrance Free


Frequently asked questions

If you place your order now, the estimated arrival date for this product is: Monday, Jul 13

Yes, absolutely! You may return this product for a full refund within 30 days of receiving it.

To initiate a return, please visit our Returns Center.

View our full returns policy here.

  • Klarna Financing
  • Affirm Pay in 4
  • Affirm Financing
  • Afterpay Financing
  • PayTomorrow Financing
  • Financing through Apple Pay
Leasing options through Acima may also be available during checkout.

Learn more about financing & leasing here.

Top Amazon Reviews


  • Highly recommend!!
Looking for the fountain of youth? Look no further! My niece is an esthetician and uses this product on all her clients aging skin. She highly recommended Bio Cream Firm for both my mom & I and we are sold! My face feels dewy, fresh & youthful… A must in your skin care routine!
Reviewed in the United States on May 6, 2026 by LSugar

  • Fabulous Product for those of Us Lovelies over 50!
I absolutely love this product, a little truly goes a long way! My esthetician gave me a 5ml sample after a treatment in case I bruised, and that tiny sample has lasted me well over a month. I use just a small dab almost every day, and it works beautifully. Highly recommend!
Reviewed in the United States on October 7, 2025 by MommaSpice

  • Love this product
Immediate results with aging skin, if you combine with gua shua.
Reviewed in the United States on March 27, 2026 by Robert Russell

  • Absolute best!
I love this cream. I’ve been using it for two years and tried other brands but always come back. I use it for my daytime hydration and my skin looks smooth and healthy! It is pricey but it works!
Reviewed in the United States on July 2, 2024 by Amazon Customer

  • Super
Used it for years.Wonderful product.
Reviewed in the United States on February 7, 2026 by Amazon Customer

  • Rejuvenates the skin
My dermatologist recommended Neocutis Bio Cream 10 years ago. She said it helps to rejuvenate the skin. One of the reasons I love this product is because it absorbs quickly and never leaves a residue or a "greasy" feeling.
Reviewed in the United States on October 19, 2025 by Kathleen Pennell

  • skin
Great product I've been using for years
Reviewed in the United States on June 8, 2025 by Starfish

  • Good moisturization
Good moisturizer
Reviewed in the United States on April 1, 2026 by alison papazian

Can't find a product?

Find it on Amazon first, then paste the link below.
Checking for best price...