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medicube

medicube Exosome Shot Zero 2,000 PPM Spicule Facial Serum | Liquid Skin Booster Serum | Exosome, AHA+BHA+PHA | Pore Care, Dead Skin Cells, Skin Texture | Korean Skincare, 1.01 fl.oz

  • Based on 3,600 reviews
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Availability: Only 5 left in stock, order soon!
Fulfilled by Amazon
Arrives Tuesday, Aug 11
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Size: 1.01 Fl Oz (Pack of 1)


Pattern Name: Zero 2,000 PPM


Features

  • Viral product beloved by everyone - Transform your skin with the Exosome + Shot Booster. Featuring a micro-sized, needle-shaped design and enriched with 15M patented Exosome shots for precise treatment, this booster delivers active ingredients directly to your pores to tackle various skin issues.
  • Exosome-Coated Technology - Harness the next-generation skincare with Exosome-coated Spicule and Exosome, penetrating deep into the skin to deliver active ingredients effectively. Our advanced formula is designed to address a range of skin concerns, from pore care to enhancing skin vitality and energy.
  • Superior Absorption & Hydration - Achieve unmatched hydration and absorption rates with our formula, which enhances active ingredient uptake by 242% compared to standalone use. Ingredients like Niacinamide and Panthenol boost skin barrier and improve hydration levels, ensuring your skin remains supple and radiant.
  • Clinically Proven & Gentle on Skin - Enjoy peace of mind with our clinically validated Tingling Ampoule that is non-comedogenic, tested to be low-irritating, gluten-free, and free from artificial colors. Suitable for all skin types, including sensitive skin.
  • Easy to Integrate into Skincare Routine - Apply our Tingling Ampoule easily with a three-step routine, starting with a cleansing pad, followed by the Zero One Day Exosome Shot, and finish with a water-based moisturizer like Medicubes Collagen Jelly Cream. For an added boost, use after the "Air Shot Mode" of the AGE-R Booster Pro to maximize effects.

Description

What are exosomes? Exosomes are tiny particles, similar to miniature bubbles, that are naturally produced by almost all types of cells. They are much smaller than cells and can carry a variety of important materials such as proteins, fats, and genetic information What is the source and function of the Lacto Exosome in Zero Exosome Shot? The Lacto Exosome in Medicube Exosome Shot is sourced from Lactobacillus, a type of beneficial bacteria that helps b Is it normal for my face to tingle after application? It contains naturally derived micro-particle ingredients, which may cause a tingling sensation upon application. This is a natural reaction as the active ingredients are being delivered to the pores. Please adjust usage based on skin sensitivity. Do I simply wash it off or do I maintain my regular skincare routine afterwards? This product is not meant to be rinsed off. Instead, it acts as a pathway to enhance skincare absorption, increasing the uptake of active ingredients by 242% compared to using cosmetics alone. Will the Spicule(Hydrolyzed sponge) dissolve on the skin or be absorbed? The spicules are designed to naturally shed along with the dead skin over several days after application. Any residual product left behind will not be absorbed into your body; instead, it will naturally dissipate. Are there any ingredients that should not be used together with it? There are no restricted ingredients with this product, but those with sensitive skin should be cautious. Perform a patch test and adjust usage based on your skin's reaction I want to focus on managing my pores. Are there any synergistic products that work well together? Using Exosome Shot with One-day Serum and Cream improves pore volume by 88% and area by 85% compared to using the shot alone. Apply Exosome Shot, then Serum, and Cream for best results. Results from tests; individual outcomes may vary. Visit the Store Visit the Store Visit the Store Visit the Store Visit the Store Visit the Store

Item model number ‏ : ‎ 8


Manufacturer ‏ : ‎ Medicube


Best Sellers Rank: #799 in Beauty & Personal Care (See Top 100 in Beauty & Personal Care) #30 in Facial Serums


#30 in Facial Serums:


Customer Reviews: 4.6 4.6 out of 5 stars (3,600)


Skin Type: All, Combination, Dry, Oily, Oily Acne Prone, Sensitive


Product Benefits: Blemishes Treatment


Target Use Body Part: Face


Scent Name: Aloe


Special Ingredients: Alpha Hydroxy, Collagen, Minerals


Item Form: Ampoule


Skin Tone: All


Brand Name: medicube


Number of Items: 1


Manufacturer: Medicube


Model Number: 8


Manufacturer Part Number: PMEKR14036


Item Weight: 30 Milligrams


Item Volume: 0.4 Kilograms


Unit Count: 1.01 Fluid Ounces


Recommended Uses For Product: Dead Skin Cells,Skin Texture


Frequently asked questions

If you place your order now, the estimated arrival date for this product is: Tuesday, Aug 11

Yes, absolutely! You may return this product for a full refund within 30 days of receiving it.

To initiate a return, please visit our Returns Center.

View our full returns policy here.

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Similar Products

Top Amazon Reviews

    • Amazing Results in Just One Week! My Skin Has Never Looked Better!
Size: 1.01 Fl Oz (Pack of 1) Pattern Name: Zero 2,000 PPM
I’ve been using the Medicube Exosome Shot Zero 2,000 PPM Serum consistently, and I’m honestly blown away by how quickly it started working. I’ve tried plenty of skincare products that promise smoother texture and smaller pores, but this is one of the few that actually delivered visible results! Within about one week, I noticed a real difference in my skin. The rough patches I usually struggle with felt softer, and my overall texture looked more refined. My skin started feeling smoother to the touch, and even my makeup applied better because the surface was more even. It wasn’t a dramatic overnight change, but it was a steady, noticeable improvement that kept getting better each day. The formula is lightweight and absorbs quickly without any sticky residue. I love that it combines exosomes with AHA, BHA, and PHA, because it gently exfoliates while supporting skin renewal, all without irritation. Even with the active ingredients, I didn’t experience redness or sensitivity, which is rare for me. I definitely feel the tingling or “needles” but it wasn’t bad at all After continued use, my skin looks healthier, clearer, and more balanced. The smoothness is the biggest difference, but I also feel like my pores look tighter and my complexion has a subtle glow that wasn’t there before. Overall, this serum has earned a permanent spot in my routine. If you’re dealing with uneven texture, dullness, or just want smoother, more refined skin, this product is absolutely worth trying. It’s one of the few skincare items where I can confidently say: I saw real results. ... show more
Reviewed in the United States on July 12, 2026 by Jamie
    • Like Microneedling in a Bottle ✨
Size: 1.01 Fl Oz (Pack of 1) Pattern Name: Zero 2,000 PPM
Review Image by Renee
Review Image by Renee
I was honestly nervous to try this after reading reviews saying it has a prickly or “spicule” feeling, but I’m so glad I started with the 2000 version. The sensation is definitely noticeable at first — kind of like a very mild microneedling effect — but on my skin it was not painful or harsh like I expected. By the next morning my skin looked smoother, brighter, tighter, and almost glass-like. My pores looked more refined and my skin texture felt softer after just a few uses. I’ve struggled with uneven texture and old acne marks over the years, and this seems to help products absorb better and gives that fresh “glow from within” look. I also appreciate that it contains exfoliating acids plus soothing ingredients, so it feels effective without completely stripping my skin barrier. I use it mostly at night followed by a moisturizer and wake up with noticeably more radiant skin. This is definitely not something I would overuse, especially if you have sensitive skin, but for me it feels like an at-home treatment that gives professional-style results without needing actual microneedling. Medicube has honestly become one of my favorite skincare brands. ... show more
Reviewed in the United States on May 28, 2026 by Renee
    • Revitalize Your Skin with a Boost of Confidence
Size: 1.01 Fl Oz (Pack of 1) Pattern Name: Zero 2,000 PPM
Review Image by Joseph K
I've tried a fair share of serums in my quest for smooth, even skin, but this liquid skin booster is a standout. It’s like a mini-facial in a bottle, designed to breathe new life into tired, uneven skin. The moment I started using it, I noticed an improvement in my skin texture and tone, especially around those pesky pores that always seem to hog the spotlight. The micro-sized, needle-like design is a fascinating touch, ensuring that the active ingredients dive right into my skin where they're needed most. With an impressive 15M patented exosome shots, this serum delivers a powerhouse of goodness directly to my pores. My skin feels more energized and vibrant, which is a delightful change from the dullness I was used to. Plus, the inclusion of AHA, BHA, and PHA means it's tackling dead skin cells head-on, leaving my complexion looking fresher than ever. What I love most is how the serum feels on my skin—it absorbs quickly without leaving any sticky residue, thanks to the superior absorption technology. Ingredients like Niacinamide and Panthenol not only boost hydration but also fortify my skin barrier, making my skin feel as supple as it looks. It's a comforting thought to know that this serum is clinically proven and gentle enough for sensitive skin like mine, free from any artificial nasties. Integrating it into my skincare routine was a breeze. The simple three-step process fits seamlessly into my day, and I can genuinely say it feels like I’m giving my skin a treat every time I use it. Whether you’re looking to refine your pores or just want to add a little extra glow to your routine, this serum might just be the secret weapon you’ve been searching for. ... show more
Reviewed in the United States on July 24, 2025 by Joseph K
    • Very Good. Not a "beginner strength" product. Prepare for prickling.
Size: 1.01 Fl Oz (Pack of 1) Pattern Name: Zero 2,000 PPM
If you're familiar at all with microneedling, this is the same idea. There are little spicy led (to y dissolving needles) in this serum that make micro channels in your skin to allow products to penetrate more deeply. It also has three gentle chemical exfoliants to smooth and brighten skin. It's a fairly thick, non-sticky serum, and it prickles quite a bit when you massage it in. I bought this on a whim and found out later that this is NOT "beginner strength". A starter serum would be a 100 ppm level. 2000 is definitely more intense and I do get some irritation immediately afterward. I own a professional grade microneedling machine, but between setting it up and sterilizing, it just feels like more of a project than I want to do for shallow, frequent needling. This serum is a nice shortcut and really, really speeds up the results I see from other products, and I use it roughly o CD a week. ... show more
Reviewed in the United States on January 5, 2026 by K. Louise
    • Fast Results, But This Stuff Is Strong!
Size: 1.01 Fl Oz (Pack of 1) Pattern Name: Zero 2,000 PPM
“I’ve been using Medicube for about a week and wanted to give a real, honest review. The first few days, my skin looked AMAZING super smooth, soft, and noticeably more glowy. I was really impressed with how quickly I saw results. I’ve used the exosome shot twice so far. After the second use, I did notice a few small breakouts and some redness, but they were in my normal breakout areas and not severe. From my experience, this seems more like an adjustment phase rather than a bad reaction. This is definitely a stronger product, so I would recommend starting slow and not overusing it. Overall, my skin still feels healthy, and I’m excited to see the long-term results once everything settles. If you have sensitive skin, just ease into it but so far, I do think it’s worth trying!” ... show more
Reviewed in the United States on April 4, 2026 by Misty smith
    • It literally Works
Size: 1.01 Fl Oz (Pack of 1) Pattern Name: Zero 2,000 PPM
Has transformed my skin. I had large poors around my nose and under eyes. After using this product for about a month it have seen so much of a difference! My skin is smooth and pore less. Not going to lie it does tingle but your skin gets used to it. I was using it 2-3 times a week and its been a staple for me in my routine. ... show more
Reviewed in the United States on July 7, 2026 by Renee
    • Great Addition to My Skincare Routine!
Size: 1.01 Fl Oz (Pack of 1) Pattern Name: Zero 2,000 PPM
I've been very impressed with this serum. It absorbs quickly, feels lightweight on the skin, and layers well with the rest of my skincare products. After consistent use, my skin feels smoother, more hydrated, and appears brighter and healthier. The formula provides a gentle boost without feeling heavy or sticky. A little goes a long way, making the bottle last longer than expected. Overall, it's a high-quality serum that delivers noticeable results and is well worth trying. ✨😊⭐💧 ... show more
Reviewed in the United States on June 8, 2026 by Magda
    • Slightly irritating, not sure about the spicules over long term
Size: 1.01 Fl Oz (Pack of 1) Pattern Name: Zero 2,000 PPM
I like medicube serums and skincare products and I have tried medicube toner pads which I liked and a moisturizer which I also liked. This is my first time trying spicules so I went easy and I did a test spot on my inner arm. I did not have a reaction, but my arm felt hyper sensitive for a few hours. This absorbed quickly, stayed a little tacky which I wasn’t too excited about but it’s doable if it works. I patch tested on my chin and I did not get a reaction. I am going to use this on my chest and for spot treatment because I am still a little concerned about teeny tiny particles going into my skin…. Look what happened with hyaluronic acid filler that everyone though was a great skin plumper—- I’m going to go easy with this.. ... show more
Reviewed in the United States on April 3, 2026 by Amazon Customer

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