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medicube Zero Exosome Shot 2,000 PPM Spicule Facial Serum | Liquid Skin Booster Serum | Exosome, AHA+BHA+PHA | Pore Care, Dead Skin Cells, Skin Texture | Korean Skin Care 1.01 fl.oz

  • Based on 5,089 reviews
Condition: New
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Availability: In Stock.
Fulfilled by Amazon

Arrives Saturday, Oct 11
Order within 7 hours and 37 minutes
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Pattern Name: Zero 2,000


Features

  • Viral product beloved by everyone - Transform your skin with the Exosome + Shot Booster. Featuring a micro-sized, needle-shaped design and enriched with 15M patented Exosome shots for precise treatment, this booster delivers active ingredients directly to your pores to tackle various skin issues.
  • Exosome-Coated Technology - Harness the next-generation skincare with Exosome-coated Spicule and Exosome, penetrating deep into the skin to deliver active ingredients effectively. Our advanced formula is designed to address a range of skin concerns, from pore care to enhancing skin vitality and energy.
  • Superior Absorption & Hydration - Achieve unmatched hydration and absorption rates with our formula, which enhances active ingredient uptake by 242% compared to standalone use. Ingredients like Niacinamide and Panthenol boost skin barrier and improve hydration levels, ensuring your skin remains supple and radiant.
  • Clinically Proven & Gentle on Skin - Enjoy peace of mind with our clinically validated Tingling Ampoule that is non-comedogenic, tested to be low-irritating, gluten-free, and free from artificial colors. Suitable for all skin types, including sensitive skin.
  • Easy to Integrate into Skincare Routine - Apply our Tingling Ampoule easily with a three-step routine, starting with a cleansing pad, followed by the Zero One Day Exosome Shot, and finish with a water-based moisturizer like Medicubes Collagen Jelly Cream. For an added boost, use after the "Air Shot Mode" of the AGE-R Booster Pro to maximize effects.

Skin Type: All, Combination, Dry, Oily, Oily Acne Prone, Sensitive


Product Benefits: Blemishes Treatment


Use for: Face


Scent: Aloe


Special Ingredients: alpha_hydroxy, collagen, minerals


Product Dimensions ‏ : ‎ 1.77 x 1.77 x 4.53 inches; 3.53 ounces


Item model number ‏ : ‎ PMEKR14036


Manufacturer ‏ : ‎ Medicube


Best Sellers Rank: #515 in Beauty & Personal Care (See Top 100 in Beauty & Personal Care) #21 in Facial Serums


#21 in Facial Serums:


Customer Reviews: 4.5 4.5 out of 5 stars 5,089 ratings


Frequently asked questions

If you place your order now, the estimated arrival date for this product is: Saturday, Oct 11

Yes, absolutely! You may return this product for a full refund within 30 days of receiving it.

To initiate a return, please visit our Returns Center.

View our full returns policy here.

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Top Amazon Reviews


  • 7500 & No pain, love this light serum, doesn’t pill and I used shot mode first & booster mode with
Pattern Name: Zero 7,500
This is a great serum, I was kind of afraid of trying it at first since I bought the higher level version at 7500 and reading reviews saying that it hurt to put on but once I did try it I was very happily surprised. My skin had a glow to it after application and there was no pain when applying. I rubbed it on my face, cheek to check then forehead then patted it on my face to absorb better and it was more like a very light tingly feeling but only when I patted the spot I was applying the serum to. This isn’t sticky on my skin, there isn’t a scent to it and it’s not painful, it’s also very light weight and comes out of the pump looking like a thin see though gel looking serum so this is one I use first before my pdrn collagen serum or any of my other Medicube serums because this EXO serum seems to be the lightest and very helpful to your skin and pores. This 7500 EXO feels very hydrating as well, I put it on and took a nap and when I woke it felt like a moisturizer on my face but didn’t rub of onto my pillows as it went into my skin, I touched my face and could still feel the very light tingle ( I can’t think of a different name then tingle but it’s more like when you pat or rub it into your face you can feel a light sensation on you face, it’s quite pleasant though.) I am so glad I didn’t purchase the 2000 version because the 7500 it just perfect. You can feel it’s on your face but no pain, I also made sure to use the booster pro age-r on shot mode and used the pore toner pads before. I have sensitive skin and this didn’t bother my face but if you have extremely sensitive skin then maybe try the 2000 first. It really depends on your skin. Personally I wouldn’t waste on the 2000 and just buy the 7500 because it is so light feeling even though you can still feel it, it kinda feels nice when applying. This doesn’t pill on your face if you want to use the booster mode after or apply another serum over it. I used the salmon pdrn serum on booster mode after I waited about 30 minutes for the pore shot serum to dry, I then used the booster mode after for the pore shot by putting it on level 2 and moving it up towards my forehead and still no pain,. Then used the salmon pdrn serum ( highly recommend! ) over it, finishing the 5 min for booster mode and had a lovely glow with pink cheeks. I wish I tried this exosome spicule shot a long time ago, it’s lovely and not painful but you can feel and tell it’s working on your face. I finished with the cooling jelly moisturizer and a collagen liquid mask once the 2 ( patted on my face by hand ) layers of moisturizer had dried. The next day my face felt and looked great with a nice glow to it and a glasssy finish which I absolutely love about the Medicube products, they due all work and makes your face look younger, also helps get rid of fine lines. This serum is an amazing product to start with after applying the toner pad and if you have a shot mode appliance by Medicube make sure to due that first ( before toner ) because it opens your pores and helps the serum penetrate deeper as does the booster mode, it helps your products go deeper into your skin and also helps the serums dry faster as they penetrate your skin deeper, saves time when you’re doing your night routine and is now a staple for me each night. Great skincare products! I love Medicube products and they actually work as well at a great price point compared to other brands. I always update my reviews if something changes, so if my opinion changes about this product I will be updating. For now I can’t wait to try the salmon pdrn EXO shot next! ... show more
Reviewed in the United States on May 3, 2025 by LeikelaKamilla

  • Great First Layer to Enhance Skin Care Products
Pattern Name: PDRN 7,500
I love the medicube 7500 serum. I use this as Part One of my tretinoin "sandwich" (on clean skin, moisturizer, tretinoin, moisturizer). After cleaning my skin with a strong exfoliant, I apply the medicube 7500 and give it a minute or two to absorb. It absorbs quickly. I then apply my tretinoin, giving that a few minutes to absorb, and I follow that with some serious moisturizing with strong skin barrier properties. After several weeks, I am seeing an improvement in the fine lines on my cheeks near my nose, and overall skin brightening and plumpness. I do this procedure every three or four days. I have mature skin that is very dry. I'm not sure if that plays any part in me not finding the 7500 to be particularly uncomfortable. Yes, you do feel some prickles as you apply the medicube and as you apply any products on top of that. For me, that prickliness is gone in a few hours, and I don't mind it at all. I've got the 7500 on subscription. I love it. ... show more
Reviewed in the United States on September 30, 2025 by Linda C.

  • Very impressed!
Pattern Name: PDRN 7,500
I'm very into PDRN skincare, and I've been absolutely loving the reedle/spicule products I've tried. This managed to be one weird fusion of the best of both of those things. I know some people can't handle the stinging feeling of these products, and I'll be fair and say it's definitely a little more intense than 100 level spicule serums. But if you feel like you could power through it for the results, this is definitely the one. It also absorbs nicely and doesn't leave sticky residue on my face that can pill up when you add your moisturizing products (which are a MUST with these formulas. It does help that PDRN in itself seems to be somewhat hydrating, but sensitive skin and overuse of this will dry your skin out.) I will definitely be buying again, it is such a quality product. I was using this, followed by popping on a very moisturizing sheet mask, and I swear my skin has never looked better. Sometimes it'd even get that bouncy/shiny glass skin look that seems unobtainable in all the ads! ... show more
Reviewed in the United States on September 12, 2025 by Emma

  • Textura ligera que mejora la apariencia de los poros
Pattern Name: Zero 7,500
Compré este suero porque buscaba algo que ayudara a controlar los poros visibles y el exceso de grasa en la zona T. Lo he usado durante dos semanas en las mañanas, antes de mi crema hidratante, y me ha sorprendido. La textura es muy acuosa y ligera, se absorbe rápido y no deja sensación grasosa, lo cual me encanta porque tengo la piel un poco grasa. Después de unos días empecé a notar que los poros se ven más afinados y la piel queda con un acabado más uniforme. Lo que podría mejorar es que el frasco trae menos cantidad de lo que esperaba y si lo usas a diario se gasta rápido. En general, es un buen suero si tienes piel mixta o grasa y quieres trabajar la textura y apariencia de los poros. ... show more
Reviewed in the United States on September 23, 2025 by María Isabel Gomez vega

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