Search  for anything...

Act+Acre Microbiome Cooling Scalp Serum - Instant Relief for Dry Itchy Scalp & Loose Flakes - Peppermint Oil & Amino Acid for Scalp Balance - Natural, Vegan, Paraben-Free Formula - 2.2 fl oz

  • Based on 38 reviews
Condition: New
Checking for the best price...

Buy Now, Pay Later


As low as $11.33 / mo
  • – 6-month term
  • – No impact on credit to apply
  • – Instant approval decision
  • – Secure and straightforward checkout

Ready to go? Add this product to your cart and select a plan during checkout.

Payment plans are offered through our trusted finance partners Klarna, Affirm, Afterpay, Apple Pay, and PayTomorrow. No-credit-needed leasing options through Acima may also be available at checkout.

Learn more about financing & leasing here.

Free shipping on this product

FREE 30-day refund/replacement

To qualify for a full refund, items must be returned in their original, unused condition. If an item is returned in a used, damaged, or materially different state, you may be granted a partial refund.

To initiate a return, please visit our Returns Center.

View our full returns policy here.


Availability: In Stock.
Fulfilled by Amazon

Arrives Thursday, May 28
Order within 8 hours and 14 minutes
Available payment plans shown during checkout

Protection Plan Protect Your Purchase
Checking for protection plans...

Features

  • VISIBLY LESS DANDRUFF: 52% reduction in the appearance of adherent dandruff at Day 30. 100% of participants showed improvement.
  • INSTANT COOLING RELIEF: Menthol and menthyl lactate soothe scalp itch on contact. Relief starts from the first application.
  • COLD PROCESSED: Made below 40C to preserve active ingredient potency. Trichologist formulated. Vegan. No rinse.
  • MICROBIOME SUPPORT: Formulated with prebiotics, postbiotics and amino acid lipids to support a balanced scalp environment
  • FREE FROM: Sulfates, silicones, parabens, synthetic fragrance. Safe for sensitive scalps.

Description

Product Features and Benefits: All-Natural, Plant-Based Ingredients Paraben- Free, Sulfate-Free, Vegan, and Cruelty-Free. The Microbiome Cooling Scalp Serum is a daily serum that balances the scalp microbiome to soothe dry scalp itch + reduce loose dandruff flakes. It is suitable for straight, curly, wavy, and coily hair types. How To Use: Apply 2-3 pipettes onto a clean scalp. Massage into the scalp. Do not rinse. Use a spot treatment on dry hair as needed for instant relief. In a clinical study, participants saw a 52% reduction in the appearance of adherent dandruff after 30 days, powered by the Amino M3 Complex. Independent ingredient clinical study by IFF / Lucas Meyer Cosmetics. Fireweed extract at 1.5%. Day 30.

Package Dimensions ‏ : ‎ 5.59 x 3.27 x 2.28 inches; 8.47 ounces


UPC ‏ :


Manufacturer ‏ : ‎ Act+ Acre


Best Sellers Rank: #86,651 in Beauty & Personal Care (See Top 100 in Beauty & Personal Care) #328 in Scalp Treatments


#328 in Scalp Treatments:


Customer Reviews: 4.2 4.2 out of 5 stars (59)


Product Benefits: Balances scalp microbiome to soothe dry scalp itch, reduce loose dandruff flakes, and provide instant cooling relief.


Hair Type: All


Scent Name: Mint


Item Form: Serum


Liquid Volume: 2.2 Fluid Ounces


Number of Items: 1


Unit Count: 2.2 Fluid Ounces


Item Volume: 2.2 Fluid Ounces


Brand Name: ACT+ ACRE


Manufacturer: Act+ Acre


UPC: 854173008970


Global Trade Identification Number: 70


Material Type Free: Paraben Free


Frequently asked questions

If you place your order now, the estimated arrival date for this product is: Thursday, May 28

Yes, absolutely! You may return this product for a full refund within 30 days of receiving it.

To initiate a return, please visit our Returns Center.

View our full returns policy here.

  • Klarna Financing
  • Affirm Pay in 4
  • Affirm Financing
  • Afterpay Financing
  • PayTomorrow Financing
  • Financing through Apple Pay
Leasing options through Acima may also be available during checkout.

Learn more about financing & leasing here.

Top Amazon Reviews


  • Concentrate on your dry patches and it'll help a lot. I didn't use it much for itching.
This worked incredibly well to cool down my scalp and reduce itchiness. I don't think I used it as described and I just kept putting more because I kept feeling crustiness so I kept putting it on. I didn't use it just for itching. I used more than I should have and I didn't let it dry in between. This worked out well for me as it completely loosened multiple layers of skin below and I was able to comb it all off and get my scalp a bit more clear when I washed my hair. It was non-greasy despite how much I excessively put on. The cost is prohibitive if I continue to use it the way I did, but I've realized that I can spot treatment the irritated patches that need to be removed. It did have a smell but for the life of me I can't remember what it was and it wasn't overpowering but I remember there being a pleasant smell that went away as it dried down. ... show more
Reviewed in the United States on April 7, 2026 by C J

  • I can wear black again
I’m on my second bottle, after more than a year of trying everything under the sun for an itchy, flaky scalp. I’m a woman in my mid-50s, menopausal, and suffering from the itching ears and scalp that can accompany the change in hormone levels. I tried various dandruff shampoos (including those that focus on the malassezia yeast), serums, and moisturizers, but nothing really worked. One day in desperation I tried putting some plain kefir on my scalp and that actually brought some relief. That seemed like a clue that my problem was related to my scalp’s microbiome. So I gave Act + Acre Microbiome serum a try and it has made a huge difference. Like I said, I’m on my second bottle. I now don’t need to apply it every day - I usually just apply after washing my hair. I also apply it to my outer ears - the itching there has abated too. ... show more
Reviewed in the United States on February 28, 2026 by RS

  • Great product in a HORRIBLE DISPENSER!
I have psoriasis and this product has really helped. I try to take a break from cortisones but my skin still needs something, and this seems to moderate the irritation. However, it has the most annoying dispenser ever. It's in a bottle with a glass dropper, but the glass is too long and not sufficiently anchored to the top, such that it's always wavering back and forth like it's about to detach from the top, so that it's impossible to put lotion on my scalp with precision, and it's hard to tell how much is coming out, which means I end up wasting a lot of product, and this stuff is not cheap. Also, the bottle top that holds the glass dropper (ie the thing you squeeze) got stuck in the indented position, and there was no way to get it unstuck to use it (though it did eventually pop up again). I noticed that their oil has a little cone top and thought, oh, I'll just swap tops, but unfortunately it didn't fit. Why don't they have a cone top on the scalp serum??? They're so much easier to use to get product onto the scalp! ... show more
Reviewed in the United States on April 13, 2026 by B.Ryan

  • I do care my scalp
helps for dry scalp. Used it and liked it so I purchased additional one.
Reviewed in the United States on December 16, 2025 by Jenny

  • A savior! No more dry and itchy scalp!
I had an itchy dry scalp and tried different oils and shampoos but nothing truly helped. Within 1 week, this product made my scalp clean. It’s so soothing and calming, and leaves my hair soft and nourished.
Reviewed in the United States on July 26, 2025 by JS

  • Horrible unpleasant strong smell
Returned, smells like mildew. Super overpowering nasty smell. Made my scalp itch worse.
Reviewed in the United States on November 24, 2025 by S. Minnich

  • feels wonderful and stays on scalp
I use gentle shampoo to protect damage and color, and once awhile I use a more harsh clarifying shampoo on my scalp leaving it tight and itchy feeling. This serum feels like heaven! I personally love the peppermint smell, but if you don't, it doesn't last long. The texture is like a liquid gel, and the migration down the hair shaft is minimal compared to a lot of serums and balms I've tried. Love it! ... show more
Reviewed in the United States on August 16, 2024 by Amazon Customer

  • Soothes hives
Works great! I’ve been battling hives all over my body for months. This is the only relief I get when they are on my scalp.
Reviewed in the United States on July 9, 2025 by Teacher Darcey

Can't find a product?

Find it on Amazon first, then paste the link below.
Checking for best price...