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Rodale

Weightless: A Doctor's Guide to GLP-1 Medications, Sustainable Weight Loss, and the Health You Deserve

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NATIONAL BESTSELLER • A board-certified physician shares her must-have guide to using GLP-1 medications, such as Ozempic, Wegovy, Mounjaro, and Zepbound, to reverse obesity and take charge of your health, with established strategies for maximizing your results “This book is a game-changer. Dr. Salas-Whalen gives you the science and the compassion this conversation has been missing. You are not alone anymore.”—Mel Robbins, 1 New York Times bestselling author of The Let Them Theory Whether your struggle to lose weight has lasted years or started more recently, GLP-1 medications will help you finally end it. While GLP-1s have redefined how we treat obesity, the search for expert care is likely to leave you feeling confused, overwhelmed, and unheard. Misconceptions are everywhere. Many doctors are still catching up with the science. And you may find a prescription but not the medical supervision you need for the best results. In Weightless, Dr. Rocio Salas-Whalen, an expert in obesity medicine, delivers the real-world strategies that have helped thousands of patients achieve health goals that once felt out of reach. Her deeply compassionate approach sees obesity, not as a personal failure but as a chronic health condition that deserves medical treatment. Drawing on years of clinical expertise and the lived experience of her patients, she explains how to: Rethink what you know about weight management: Learn why “eat less, move more” is an outdated and ineffective prescription.Give your GLP-1 journey a strong start: Choose an experienced provider, ask the right questions at every appointment, and get better outcomes if you’re using telehealth.Preserve muscle for long-term success: Follow Dr. Salas-Whalen’s advice for increasing protein intake and optimizing your strength training.Protect your progress: Manage side effects with evidence-based care, recognize when you need a dosage change, and know what to do when GLP-1s don’t work.Adjust to life after GLP-1s: Navigate the unexpected physical, social, and psychological changes that accompany significant weight loss. Comprehensive and empowering, Weightless offers judgment-free support that ensures you never feel alone on this journey. Read more

Publisher ‏ : ‎ Rodale Books


Publication date ‏ : ‎ December 30, 2025


Language ‏ : ‎ English


Print length ‏ : ‎ 288 pages


ISBN-10 ‏ : ‎ 0593981200


ISBN-13 ‏ : ‎ 07


Item Weight ‏ : ‎ 1.25 pounds


Dimensions ‏ : ‎ 6.35 x 1 x 9.52 inches


Best Sellers Rank: #570 in Books (See Top 100 in Books) #1 in Weight Loss Diets (Books) #1 in Other Diet Books


#1 in Weight Loss Diets (Books):


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Top Amazon Reviews

    • A Guide That Removed the Fear and Gave Me Real Hope on My GLP-1 Journey A Guide That Removed the Fear and Gave Me Real Hope on My GLP-1 Journey
Format: Hardcover
Review Image by Mr. Bernardo J. Torres
This book has been an incredibly helpful guide as I began my GLP-1 journey. I was honestly nervous and unsure about what to expect, but Dr. Rocio Salas-Whalen explains everything in a clear, supportive, and practical way that immediately made me feel more confident. What made this book especially meaningful for me is how deeply understood I felt while reading it. I have been aware of my weight since I was about eight years old. For most of my life there has been a constant internal battle. I blamed myself, felt like my body was something I needed to fix, and wondered why my efforts never seemed to match the results. I have always been an active person. I run marathons. Yet the weight gain still happened, especially once perimenopause began, and it left me feeling stuck and frustrated for years. Growing up in Mexico as the oldest granddaughter in my family, my weight was often a topic of conversation. Everyone had an opinion. Over time that created a lot of shame and emotional pain around my body. Reading this book helped me begin to release some of the blame I have carried for so long. It explains in a compassionate and scientific way how hormones, metabolism, and other biological factors influence weight, and it helped me understand that this is not simply a matter of willpower. In just one month of following the guidance in this book and starting treatment, I have already lost a meaningful amount of weight after years of feeling completely stuck. More importantly, I feel like I finally understand what my body is going through and how these medications fit into a broader and thoughtful health strategy. What I appreciated most is the empathy throughout the book. It removes fear and confusion and replaces it with knowledge, compassion, and practical guidance. It helps you understand what questions to ask, what to expect, and how to approach this journey in a sustainable way. It truly feels like having a knowledgeable doctor walking you through each step. I am deeply grateful to Dr. Salas-Whalen for writing this. I can honestly say I have never felt so seen and validated by an author. For anyone considering GLP-1 medications but feeling uncertain or overwhelmed, this book can make a tremendous difference. It certainly did for me. ... show more
Reviewed in the United States on March 15, 2026 Reviewed in the United States on March 15, 2026 by Mr. Bernardo J. Torres
    • For anyone contemplating a GLP1 to lose weight, this is a MUST read!
Format: Kindle
I recently bought “Weightless” by Rocio Salas-Whalen, MD and it completely changed the way I think about weight loss and obesity. What I appreciated most was how clearly she explains the science behind weight and hormones, especially how medications like GLP-1s work in the body. It made me realize that weight struggles are not simply about willpower, but often about biology and how our bodies regulate hunger and metabolism. The book is very easy to understand, even though it covers a lot of medical information. I also loved the compassionate tone throughout—it really helps remove the shame that so many people feel about their weight. Instead of focusing on restrictive dieting, she emphasizes sustainable habits, protecting muscle, eating enough protein, and using medication responsibly when it’s appropriate. Overall, “Weightless” felt empowering and hopeful and it has definitely helped me on my own journey. It helped me understand why traditional dieting can fail and why newer treatments can be life-changing for many people. I would definitely recommend this book to anyone interested in learning more about modern weight-loss treatments and the science behind them. I truly can’t say enough positive things about this book! This information in this book and the medication are changing my life! I have had two strokes and have high blood pressure and I am now hopeful that I can be healthy again. I have bought the book for my daughter and have recommended to other family members as well. ... show more
Reviewed in the United States on April 14, 2026 by Amazon Customer
    • Book for doctors & patients both!
Format: Hardcover
As a metabolic psychiatrist, I rarely come across books that truly reflect what we see in real clinical practice— 📘 Weightless is one of them. Brilliantly written by Rocio Salas-Whalen, it captures the complexity of weight, hormones, and metabolism in a way that is both scientific and practical. Highly recommended for both patients and clinicians. ... show more
Reviewed in the United States on March 31, 2026 by saeed khan
    • Key points
Format: Hardcover
Great asset to have, key points needed by users, subjects are easy to find. Author should write more on GLP1 maintenance and not politics. Great starter book.
Reviewed in the United States on March 8, 2026 by Clove
    • This Book Changed How I See Obesity Medicine — And My Own Family's Story
Format: Kindle
I'm a chef and culinary educator with over 20 years in the food industry. My work has always been about helping people build a real relationship with food — but lately, that work has been pulling me toward something bigger: the space where food, health, and medicine actually meet. That's what brought me to this book. What I didn't expect was how personally it would land. I have people in my family whose life has been marked by obesity. For years I watched them struggle — and I watched the world tell them it was their fault. Dr. Salas-Whalen names that for what it is: wrong. Obesity is a disease. It deserves real medical treatment. Reading this book gave me something I didn't know I was missing around this topic: hope. Professionally, what resonated most was her insistence that medication alone is never enough — that protein, movement, and sustainable habits are what make the difference long-term. That's exactly what I teach. These aren't shortcuts. They're tools, and like any tool, they only work if you use them right. The sections on managing side effects, knowing when to adjust your dose, and navigating life after significant weight loss are worth the book alone. Nobody talks about that last part, and she does it with honesty and grace. If you're a patient, a caregiver, or a health professional working at this intersection — read it. — Edna Cochez | Chef & Culinary Educator | Chef Edna Cochez Digital Platform | Panama ... show more
Reviewed in the United States on April 6, 2026 by Edna Cochez
    • Practical, Encouraging, and Educational
Format: Hardcover
This encouraging book is chock full of great information and guidance from an MD specializing in obesity medicine for over 15 years. As someone who has seen it all, including the explosion of GLP-1’s in recent years, her guidance is practical and trust-worthy. I’ve been on Zepbound for around 5 months, and have been frustrated by a weight loss plateau that has lasted for weeks. This book helped me through it, calmed me down and showed me many other things to be looking at besides weight loss. Her practical advice answers any question you might have about obesity medications, whether you are thinking about them, have already started, or have been on them for some time. I considered myself pretty knowledgeable before reading this book, but I learned so much more! Dr. Salas-Whalen writes in an encouraging way, and her book includes stories from her many clients. It is so helpful and encouraging, and made me feel like I had my own personal highly trained doctor and coach. Buy it, you won’t regret it!! ... show more
Reviewed in the United States on March 10, 2026 by Lynne G.
    • Everything One Needs To Know While on a GLP
Format: Audiobook
This is a fabulous book. Rocio Salas-Whalen MD gives a thorough experience of all one needs to know about using a GLP. Among other things, she discusses the history and future of GLPs. Talks about everything a GLP patient needs to get out of their doctor who is prescribing, and everything patients need to do to have an effective experience. Wish I had this book the first time I used a GLP, would have made a huge difference. My current doctor asks her patients to read this book and we track and discuss all of the issues Salas-Whalen says to monitor. It's a much more comprehensive experience and I'm losing body fat this time, instead of fat and muscle. ... show more
Reviewed in the United States on April 22, 2026 by Julia C
    • Empowering, Informative, Must-Read for Anyone Exploring GLP-1 Medications
Format: Hardcover
Weightless by Dr. Salas-Whalen is an empowering and informative read that goes far beyond explaining GLP-1 medications. Dr. Salas-Whalen provides science-based, easy-to-understand insight into metabolic health, helping readers better understand the root causes of weight struggles and how to take control of their health and their lives. What makes this book stand out is the balance between medical expertise and compassionate guidance. The information is presented in a clear, relatable way, making complex topics accessible without feeling overwhelmed. Whether you are considering GLP-1 medications or simply want to improve your overall metabolic health, this book offers practical knowledge and hope. ... show more
Reviewed in the United States on May 23, 2026 by Jose E.

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