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medicube Exosome Shot Zero 25,000 PPM Spicule Facial Serum | Liquid Skin Booster Serum with Exosome, AHA+BHA+PHA - Pore Care, Dead Skin Cells, Skin Texture, Korean Skincare, 0.43 fl.oz

  • Based on 474 reviews
Condition: New
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Availability: In Stock.
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Arrives Saturday, Aug 22
Order within 16 hours and 44 minutes
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Size: 0.43 Fl Oz (Pack of 1)


Pattern Name: Zero 25,000 PPM


Features

  • TIKTOK VIRAL - Transform your skin with the Exosome Shot Skin Booster Serum. Featuring a micro-sized, needle-shaped design and enriched with 15M patented Exosome shots, this booster provides targeted care, delivering active ingredients to the skin for a revitalized look.
  • More powerful intensive pore care - While using the Zero Exosome Shot Serum, you may experience a slight tingling sensation, which is completely normal. This indicates skin texture improvement and proves the formula is working effectively.
  • Exosome-Coated Technology - Harness next-generation skincare with Exosome-coated Spicule and Exosome technology, designed to deliver active ingredients to the skins surface effectively. Our advanced formula addresses a range of skin concerns, from pore care to enhancing skin vitality and energy.
  • Easy to Integrate into Skincare Routine - Apply our Tingling Ampoule once a week as the first step in your skincare routine. It helps improve skin texture and provides intensive pore care.

Product Dimensions ‏ : ‎ 4.72 x 1.97 x 5.91 inches; 15.87 ounces


Manufacturer ‏ : ‎ Medicube


Best Sellers Rank: #1,367 in Beauty & Personal Care (See Top 100 in Beauty & Personal Care) #42 in Facial Serums


#42 in Facial Serums:


Customer Reviews: 4.4 4.4 out of 5 stars (474)


Skin Type: All


Product Benefits: Hydrating, Pore Treatment, Skin texture


Target Use Body Part: Face


Special Ingredients: Lacto Exosome, AHA, BHA, PHA


Item Form: Ampoule


Brand Name: medicube


Number of Items: 1


Manufacturer: Medicube


Manufacturer Part Number: PMEKR14040


Item Weight: 0.45 kg


Item Volume: 25 ml


Active Ingredients: Lacto Exosome, AHA, BHA, PHA


Frequently asked questions

If you place your order now, the estimated arrival date for this product is: Saturday, Aug 22

Yes, absolutely! You may return this product for a full refund within 30 days of receiving it.

To initiate a return, please visit our Returns Center.

View our full returns policy here.

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Top Amazon Reviews


  • Astounding Results!
Size: 0.43 Fl Oz (Pack of 1) Pattern Name: Zero 25,000 PPM
I used this product the night after receiving it. I can't say at the time of ordering that I was convinced as other reviewers mentioned, "It's as good as microneedling. I microneedle about once per month in hopes that my skincare actives with absorb deeper into the skin. I have seen slight improvements from this process. I was intrigued by the Medicube Exosome Shot. Most of the reviews were positive, and since the emphasis was on treating large pores, I finally decided to give the product a try. First of all, unlike microneedling, there was no discomfort for me. There was a mild prickly sensation that I did not find unpleasant. Quite the opposite, I found the sensation comfortable, as well as promising because it was indicative that the product was actually performing. I have the stronger 25000 shot as advised by another reviewer. First, I cleansed my face and patted dry. I followed up with low strength glycolic pads to remove any residual makeup. After rinsing and patting dry again, I proceeded with my first Exosome treatment. It did take numerous pumps before the product came out (so be patient). Upon the first very small amount, I applied to my cheeks, gently massaging in as instructed. I could feel the prickly sensation of the spicules right away. I proceeded with my entire face, avoiding the eye area. I did take the product up into the temporal area. After feeling satisfied that I had massaged enough, I applied hyaluronic acid serum. Much to my surprise, this, too, caused the prickly sensation, making me feel as though my skin was reaping full benefits of the actives. Next, I applied Resveratol serum, followed by my moisturizer with peptides and other actives. All these subsequent skin care applications caused a mild warmth along with the same prickling. Here's the most amazing part, early the next morning while washing my hands, I noticed my skin had a glowy look. I had forgotten about the Exosome treatment until I looked closer. I put on my glasses and had my nose within a couple of inches of the mirror. I couldn't see a single pore. "Too good to be true," I thought, I moved to a another mirror with different lighting. Same outcome, I couldn't see a single pore! I had always heard that pores are pores and you can't really shrink them, especially with age. I am 62. With my own eyes, I see that my pores are no longer visible after just one treatment of Medicube Exosome Shot! I will continue to use this product, as I thought there was no hope for my large pores. It's my estimation that with long-term use, the active ingredients of my additional products will better reduce my wrinkles since those spinules are a game changer. Better than microneedling? Absolutely. I can't recommend this product enough. ... show more
Reviewed in the United States on May 11, 2025 by Gin

  • Amazing stuff- simulates micro needling
Size: 0.43 Fl Oz (Pack of 1) Pattern Name: Zero 25,000 PPM
This stuff is powerful and works well. I use it to soak the collagen jelly in a bit better, before all my actives, and it's amazing. My skin looks better than it had in years
Reviewed in the United States on July 21, 2026 by April

  • Spicy but concentrated
Size: 0.43 Fl Oz (Pack of 1) Pattern Name: Zero 25,000 PPM
This is the highest concentration exosome serum I've found. My skin is not particularly sensitive but I found this serum to have a very unusual sensation. Almost as if you're rubbing tiny shards of not so sharp glass into your skin. It's not painful, more uncomfortable and it's not so bad that I can't stand it but the sensation was so weird I put it on my hand and what's even more strange is that I didn't feel it on my bad. I wonder if maybe it reacted with something I already put on my face. I didn't turn red. I'll still give it four stars based on value. ... show more
Reviewed in the United States on January 23, 2026 by Sunny Bogden

  • Incredible results for acne scars – a must-have, but be mindful of the "tingle"!
Size: 0.43 Fl Oz (Pack of 1) Pattern Name: Zero 25,000 PPM
I’ve been testing the medicube Exosome Shot Zero on my skin, and the results have been impressive. Redness Reduction: As you can see in my photos, the redness from my acne scar faded significantly in just four days, to the point where it’s barely noticeable. Targeted Use: I tested this specifically on the spot on my nose and left the spot above my lip untreated as a control. The difference is clear; this pen really works to calm redness. Application Tips & Precautions: Tingle Factor: Like the other "spicule" products, this one does tingle when you apply it. It can cause some itching and discomfort for a few minutes, though it usually feels fine by the next morning. If you have very sensitive skin, please use caution! Best Application Method: Because of the pen-like tip, I recommend applying it gently rather than rubbing it in with your hands. Use the tip to lightly massage and distribute the serum precisely where you need it. I find it works best as a targeted spot treatment. If you can handle the slight tingling sensation, this is an excellent tool for targeting specific skin concerns. Highly recommended! ... show more
Reviewed in the United States on July 8, 2026 by Can

  • I’ll give this five stars
Size: 0.43 Fl Oz (Pack of 1) Pattern Name: Zero 25,000 PPM
I cannot say enough about this product. It is wonderful and has done some awesome goodness to my skin . I would use this again. I most definitely will purchase it again..
Reviewed in the United States on July 22, 2026 by Wanda Boyd

  • Great product great price
Size: 0.43 Fl Oz (Pack of 1) Pattern Name: Zero 25,000 PPM
I definitely recommend this it is wonderful you feel it immediately on your face
Reviewed in the United States on July 18, 2026 by Joetta Jones

  • I personally wouldn't recommend
Size: 0.43 Fl Oz (Pack of 1) Pattern Name: Zero 25,000 PPM
I honestly feel like the 7500 worked just fine. This didn't provide anything more than the weaker version for me. I wouldn't purchase again.
Reviewed in the United States on July 10, 2026 by Teala Abbott

  • refreshing
Size: 0.43 Fl Oz (Pack of 1) Pattern Name: Zero 25,000 PPM
I absolutely love this. I keep it in the refrigerator. Refreshing and shrinks my eye bags.
Reviewed in the United States on July 29, 2026 by Judy R.

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