medicube Exosome Shot Zero 25,000 PPM Spicule Facial Serum | Liquid Skin Booster Serum | Exosome, AHA+BHA+PHA | Pore Care, Dead Skin Cells, Skin Texture | Korean Skincare, 0.43 fl.oz
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Availability:
In Stock.
Arrives
Thursday, Aug 13
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Pattern Name: Zero 25,000 PPM
Features
- TIKTOK VIRAL - Transform your skin with the Exosome Shot Skin Booster Serum. Featuring a micro-sized, needle-shaped design and enriched with 15M patented Exosome shots, this booster provides targeted care, delivering active ingredients to the skin for a revitalized look.
- More powerful intensive pore care - While using the Zero Exosome Shot Serum, you may experience a slight tingling sensation, which is completely normal. This indicates skin texture improvement and proves the formula is working effectively.
- Exosome-Coated Technology - Harness next-generation skincare with Exosome-coated Spicule and Exosome technology, designed to deliver active ingredients to the skins surface effectively. Our advanced formula addresses a range of skin concerns, from pore care to enhancing skin vitality and energy.
- Easy to Integrate into Skincare Routine - Apply our Tingling Ampoule once a week as the first step in your skincare routine. It helps improve skin texture and provides intensive pore care.
Product Dimensions : 4.72 x 1.97 x 5.91 inches; 15.87 ounces
Manufacturer : Medicube
Best Sellers Rank: #84 in Beauty & Personal Care (See Top 100 in Beauty & Personal Care) #5 in Facial Serums
#5 in Facial Serums:
Customer Reviews: 4.2 4.2 out of 5 stars (333)
Skin Type: All
Product Benefits: Hydrating, Pore Treatment, Skin texture
Target Use Body Part: Face
Special Ingredients: Lacto Exosome, AHA, BHA, PHA
Item Form: Ampoule
Brand Name: medicube
Number of Items: 1
Manufacturer Part Number: PMEKR14040
Manufacturer: Medicube
Item Weight: 0.45 Kilograms
Item Volume: 25 Milliliters
Active Ingredients: Lacto Exosome, AHA, BHA, PHA
Frequently asked questions
If you place your order now, the estimated arrival date for this product is:
Thursday, Aug 13
Yes, absolutely! You may return this product for a full refund within 30 days of receiving it.
To initiate a return, please visit our Returns Center.
View our full returns policy here.
To initiate a return, please visit our Returns Center.
View our full returns policy here.
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Similar Products
Top Amazon Reviews
Pattern Name: Zero 25,000 PPM
This helps dry out any blemishes over night. Works better than any pimple patches I have ever used! Great Value, and skin feels soft not dry.
Reviewed in the United States on April 16, 2026 by T. Morales
Pattern Name: Zero 25,000 PPM
I used this product the night after receiving it. I can't say at the time of ordering that I was convinced as other reviewers mentioned, "It's as good as microneedling. I microneedle about once per month in hopes that my skincare actives with absorb deeper into the skin. I have seen slight improvements from this process. I was intrigued by the Medicube Exosome Shot. Most of the reviews were positive, and since the emphasis was on treating large pores, I finally decided to give the product a try. First of all, unlike microneedling, there was no discomfort for me. There was a mild prickly sensation that I did not find unpleasant. Quite the opposite, I found the sensation comfortable, as well as promising because it was indicative that the product was actually performing. I have the stronger 25000 shot as advised by another reviewer. First, I cleansed my face and patted dry. I followed up with low strength glycolic pads to remove any residual makeup. After rinsing and patting dry again, I proceeded with my first Exosome treatment. It did take numerous pumps before the product came out (so be patient). Upon the first very small amount, I applied to my cheeks, gently massaging in as instructed. I could feel the prickly sensation of the spicules right away. I proceeded with my entire face, avoiding the eye area. I did take the product up into the temporal area. After feeling satisfied that I had massaged enough, I applied hyaluronic acid serum. Much to my surprise, this, too, caused the prickly sensation, making me feel as though my skin was reaping full benefits of the actives. Next, I applied Resveratol serum, followed by my moisturizer with peptides and other actives. All these subsequent skin care applications caused a mild warmth along with the same prickling. Here's the most amazing part, early the next morning while washing my hands, I noticed my skin had a glowy look. I had forgotten about the Exosome treatment until I looked closer. I put on my glasses and had my nose within a couple of inches of the mirror. I couldn't see a single pore. "Too good to be true," I thought, I moved to a another mirror with different lighting. Same outcome, I couldn't see a single pore! I had always heard that pores are pores and you can't really shrink them, especially with age. I am 62. With my own eyes, I see that my pores are no longer visible after just one treatment of Medicube Exosome Shot! I will continue to use this product, as I thought there was no hope for my large pores. It's my estimation that with long-term use, the active ingredients of my additional products will better reduce my wrinkles since those spinules are a game changer. Better than microneedling? Absolutely. I can't recommend this product enough.
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Reviewed in the United States on May 11, 2025 by Gin
Pattern Name: Zero 25,000 PPM
Visible Results After One Use This is a once-every-seven-days treatment for me, and I used it for the first time last night. No irritation, no issues at all during or after application. This morning, I actually received my first unsolicited compliment on my skin — what a nice surprise! My skin looks smoother, clearer, and more refreshed already. For something used only once a week, that feels like a real turnaround. Too early to speak long-term, but first impression is very promising. I’ll definitely continue using it.
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Reviewed in the United States on January 12, 2026 by Jana Dreams in Color
Pattern Name: Zero 25,000 PPM
This is the highest concentration exosome serum I've found. My skin is not particularly sensitive but I found this serum to have a very unusual sensation. Almost as if you're rubbing tiny shards of not so sharp glass into your skin. It's not painful, more uncomfortable and it's not so bad that I can't stand it but the sensation was so weird I put it on my hand and what's even more strange is that I didn't feel it on my bad. I wonder if maybe it reacted with something I already put on my face. I didn't turn red. I'll still give it four stars based on value.
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Reviewed in the United States on January 23, 2026 by Sunny Bogden
Pattern Name: Zero 25,000 PPM
I’m such a medicube fan. This is typical medicube quality, which to me, is amazing. It does sting a tiny bit when you’re putting it on, but I literally feel it for seconds and it’s more of like a tingly-stingy sensation. Not painful at all. I wake up the next morning and my skin looks incredible.
Reviewed in the United States on April 14, 2026 by Kenzie Schrock
Pattern Name: Zero 25,000 PPM
UPDATE BELOW!!!!! And ANOTHER BELOW THAT! Photos are from 3rd review. LOOK CLOSELY at my Photos of the Bottles! 1 works, 1 DOES NOT! Might be expired?!!! Wow! This stuff is legit. I randomly found this on Amazon when looking for skin care products for my 14 year old daughter. I didn’t get this for her. I got it for myself. This product is too inexpensive and good to be true, only it is true! Tbh, I didn’t really research it before I bought it and used it. It was after I used it and how amazing it worked that I started looking more into the product. The 25,000 ppm dose. After just one time of using it, I was in shock as to how soft and smooth textured my skin was. The bottle doesn’t give the best directions about how much to apply so I just started squeezing a little and rubbing it in and a little more and more and more. I probably did about 7 full pumps. It absorbs and dries in just a minute or so. It doesn’t dry sticky or anything. It’s just like a standard nice serum. Now the big thing that all the hype or fear is about is the way it feels. Some say it’s torturous and feels like you are sticking your face in fiber glass or a cactus or something. I beg to differ. Well it does feel a little prickly for sure but it feels more like something that is getting deep in your skin. It feels like it’s working basically. What I noticed now after using this maybe 5 or 6 times over the last 3 weeks is that when you put it on you have 2 options. You can let it sit or you can put your night cream on. I let it sit for about 10 minutes and it does prickle but then I put my heavy night cream on. At first, the night cream makes it feel a little more prickly but then it really starts to just fade away. The longer you leave it sitting without heavy cream the pricklier it gets. I’m pretty tough, so I decided one time to put coconut oil on instead of night cream. Now that enhanced the prickles big time because it’s a carrier oil. But honestly that time was when I got the absolute most and best results from it. I don’t think you have to be afraid of this product at all and it’s prickles. I think you just need to know your limits. If you are sensitive and don’t like the feeling, just try it on your nose or in small areas. Noses are a little more tough because they are exposed to weather more so than other areas of the face, so they aren’t as sensitive. But my nose is actually one of the areas I found that it helped me the most. Cleaned my pores out completely and whether or not it shrunk them, I’m not sure but it sure looks like it to me. The very first thing I thought after seeing results was that something was wrong because this product should be going for probably $150 now $18 or $20. It’s too reasonably priced to not try and I’m almost positive if you can handle a little prickling feeling, you will be stoked on the results. I went and bought like 5 more of them because I was worried that the price would make a huge jump since it was so good. Oh and ready for a little bit of redness that goes away the next day or 2 days and longer pricklies if you use coconut oil but no peeling at all! After the research I realized how innovative and way far beyond the science being used in the USA. Totally worth every penny and feels like you are saving hundreds on micro needling because it has very similar results. I’m so done with micro needling now! Sorry to go off but seriously! I am just in total shock how well this stuff works and how amazing my skin looks. I will post a pic but not right now because I’m in a hurry and shouldn’t even be posting but I couldn’t help it!! My update using my second bottle of medicine Exosome Shot Zero 25,000 This one is not the same as the first one. I purchased it from Medicube on Amazon and absolutely nothing happened when I put it on my face! I’m really disappointed because that first one was absolutely amazing. This one has no prickly feeling. It feels like a face lotion or serum with no active ingredients. I have done absolutely nothing different from using the first container. So sadly now I am going to have to change my review from 5 stars 100% to 1 since there is no zero stars. What a bummer! I guess it’s the luck of the draw. I’m returning this one for sure and I hope that someone sees this part of the review and does some testing or something to make sure the potency is dispersed evenly among ther bottles! So so sad because I would have continued on to buy this forever pretty much. I have 4 more. I guess I will test them all and send back any and all that don’t work. Ahhh I’m so bummed! Another Update- putting bottles bought together side by side!!! Look at the photos! The one with the BOLD FONT on the right totally works! The other one does NOT! So BEWARE! Return before opening I guess if you get one that doesn’t have the bold font on the entire top section and a little lower where it says “Read instructions and caution before use.” And the word “Directions” lower down and the distribution info at bottom! Make sure it’s in bold!!!
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Reviewed in the United States on January 28, 2026 by Monishegone