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Osteo Bi-Flex One Per Day Vitamin D Supplement, Improve Joint Function, Support Bone and Immune Health, 130 Coated Tablets

  • Based on 7,339 reviews
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Arrives Wednesday, Jul 29
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Size: 130 Count (Pack of 1)


Features

  • DAILY JOINT AND BONE SUPPORT: This joint support supplement is formulated with Glucosamine, Vitamin D, and Joint Shield 5-LOXIN Advanced(R) for improved joint function and bone health (1)
  • NUMBER 1 PHARMACIST RECOMMENDED BRAND(3): Osteo Bi-Flex(R) has been a trusted leader in joint health for years; and our joint health supplements bring you that clinically studied Joint Shield 5-Loxin Advanced(R) in every serving (1)
  • FAST RESULTS: Osteo Bi-Flex(R) One Per Day is formulated with 5-Loxin Advanced(R), which is a highly concentrated herbal extract that improves joint comfort in as little as seven days(2)(1)
  • 5 JOINT HEALTH BENEFITS: Osteo Bi-Flex(R) One Per Day supports joint mobility, flexibility, strength, function, and comfort, so you can get back to the things that move you with science-backed support (1)
  • CELEBRATE LIFE IN MOTION: You were made to moveso move well with these One per Day Vitamin D formulated supplement designed to keep up with your active lifestyle

Description

Osteo Bi-Flex (R) One Per Day is a great and convenient way to support daily bone and joint health. From the Number 1 pharmacist recommended joint health brand(3) One Per Day is formulated with Glucosamine, Joint Shield 5-Loxin Advanced(R), and Vitamin D for five joint health benefits, including mobility, flexibility, strength, function, and comfort. (1) Glucosamine helps promote healthy joints and comfortable movement. (1) While 5-Loxin Advanced, a concentrated herbal extract is clinically shown to improve joint comfort in just 7 days (2) with Vitamin D offering added bone support. (1) Whether you're looking for joint supplements to stay active or supplements to support joint mobility, One Per Day fits seamlessly into any routine.

Product Dimensions ‏ : ‎ 2.86 x 2.86 x 5.3 inches; 10.88 ounces


Item model number ‏ : ‎ 31734


Date First Available ‏ : ‎ February 1, 2021


Manufacturer ‏ : ‎ Nature's Bounty


Best Sellers Rank: #1,533 in Health & Household (See Top 100 in Health & Household) #2 in Glucosamine Nutritional Supplement


#2 in Glucosamine Nutritional Supplement:


Customer Reviews: 4.6 4.6 out of 5 stars (7,339)


Brand Name: Osteo Bi-Flex


Primary Supplement Type: Glucosamine HCI


Item Form: Tablet


Diet Type: Gluten Free


Product Benefits: 130


Age Range Description: Adult


Container Type: Bottle


Dosage Form: Tablet


UPC: 030768003302


Manufacturer: Nature's Bounty


Manufacturer Part Number: 31734


Model Number: 31734


Unit Count: 130 Count


Item Weight: 0.68 Pounds


Item Dimensions: 2.86 x 2.86 x 5.3 inches


Number of Items: 1


Flavor: Unflavored


Special Ingredients: Joint Shield 5-LOXIN Advanced


Material Features: Gluten Free


Color: N/a


Frequently asked questions

If you place your order now, the estimated arrival date for this product is: Wednesday, Jul 29

This item is non-returnable:

Non-returnable due to Food safety reasons

View our full returns policy here.

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Top Amazon Reviews


  • Quietly Effective
Size: 130 Count (Pack of 1)
On the recommendation of my doctor for arthritic knee pain, I started taking osteo bi-flex and have now taken it for years. I have found osteo bi-flex to be quietly effective by that I mean, you don’t realize how effective it is until you stop taking it. It gradually reduced my knee pain over time to the point I thought it had gone away on its own until I decided to stop taking the osteo at which point, the pain returned with a vengeance. I like this particular supplement because it is just one pill instead of 2-4 now granted that one pill is the size of two pills but I only have to swallow it once. If you have problems getting pills down, this may be too large to swallow in which case you can use the smaller multi pill supplements. There is no taste to osteo so it won’t cause a gag-reflex but, the one dose option is much larger than a normal pill. If you have mild to moderate joint discomfort I would definitely recommend trying osteo bi-flex before a prescription medication just make sure to give it enough time to notice a change. ... show more
Reviewed in the United States on May 27, 2026 by Amazon Customer

  • It Works.
Size: 120 Count (Pack of 1)
I was skeptical of the Osteo Bi-Flex claims of benefits, particularly of the 7 day improvement , however, after using it for about a week, I can attest to the remarkable effects. Osteo Bi-Flex® is the only brand to feature the revolutionary formulation of ingredients in Joint Shield(tm), with patent-pending ingredient 5-LOXIN Advanced(tm). Taking 5-LOXIN Advanced(tm) showed improvement in joint comfort within 7 days.1 Joint Shield(tm) with 5-LOXIN Advanced(tm) works to guard against the action of enzymes that affect joint health.* 5-LOXIN Advanced(tm) is a super concentrated extract of Boswellia serrata, which helps with joint flare-ups.* Osteo Bi-Flex® self reports that it is manufactured under the strictest standards for product purity and potency. It is made exclusively with naturally sourced Glucosamine. A publication discussing the use of glucosamine sulfate and chondroitin sulfate (the most common forms of the supplements) to treat knee osteoarthritis was published in the July 14, 2003, issue of The Archives of Internal Medicine. The publication reviewed the best studies from 1980 to 2002, and concluded: "Our results demonstrated a highly significant efficacy of glucosamine on all outcomes, including joint space narrowing." The paper also found chondroitin "effective" on several outcomes measures, and added, "Safety was excellent for both compounds." One of the most discussed glucosamine study was published in a medical journal in 1999, and involved a group of Navy SEALS. The study authors noted: "Osteoarthritis is not unexpected in this occupational setting, given the history of high levels of activity and trauma." The publication presented SEALS as study subjects who all suffered from knee osteoarthritis before beginning a proper (double blind, randomized) 16-week study. Half of the subjects took a supplement containing glucosamine hydrochloride, chondroitin sulfate, and manganese ascorbate and the other half took a placebo. "The relief of knee discomfort was the most important finding of this study," the researchers concluded. "Knee osteoarthritis symptoms were relieved" for the SEALS who took the supplements, That assessment was determined by both by questioning the patients and by examining their knees. My personal experience is similar. My left knee no longer clicks (damaged meniscus) with the frequency that it did for a half-dozen years and I can do squatting and lunging exercises without pain now. As a result I can again weight train regularly to rehabilitate and strengthen my legs. I'm knocking 55 and looking forward to an upcoming week of skiing in Colorado now. If your not allergic to shellfish, try it yourself. I am confident that you will realize the value and benefits of Osteo Bi-Flex Triple Strength. Keep in mind: The U.S. Food and Drug Administration (FDA) does not regulate dietary supplements in the same way it regulates medicines. A dietary supplement can be sold with limited or no research on how well it works. Always tell your doctor if you are using a dietary supplement or if you are thinking about combining a dietary supplement with your conventional medical treatment. It may not be safe to forgo your conventional medical treatment and rely only on a dietary supplement. This is especially important for women who are pregnant or breast-feeding. When using dietary supplements, please note: Like conventional medicines, dietary supplements may cause side effects, trigger allergic reactions, or interact with prescription and nonprescription medicines or other supplements you might be taking. A side effect or interaction with another medicine or supplement may make other health conditions worse. The way dietary supplements are manufactured may not be standardized. Because of this, how well they work or any side effects they cause may differ among brands or even within different lots of the same brand. The form of supplement that you buy in health food or grocery stores may not be the same as the form used in research. Other than for vitamins and minerals, the long-term effects of most dietary supplements are not known. For further information to some research and consult your doctor. ... show more
Reviewed in the United States on January 27, 2013 by Cosmos

  • Great product
Size: 120 Count (Pack of 1)
Works great for the arthritic pain in my husbands knees.
Reviewed in the United States on June 5, 2026 by Kit Thompson

  • Provides some relief from knee joint stiffness and pain… Provides some relief from knee joint stiffness and pain…
Size: 130 Count (Pack of 1)
In my senior years, knee joint stiffness and occasional pain has haunted me. In younger years, many-many miles of running for wrestling, football, baseball and track has created worn joints. After looking for solutions to the stiffness and pain, I read about glucosamine as a dietary supplement. I started taking Osteo Bi-Flex a couple years ago. I take the one/day dosage and after a week or so, I felt quite a bit of relief. I’ve been taking it ever since. The pills are large and not the easiest to swallow. They do have a smaller tablet size available, but the cost is higher. ... show more
Reviewed in the United States on February 13, 2026 Reviewed in the United States on February 13, 2026 by Jack’s Facts

  • Osteo Bi-Flex Triple Strength Glucosamine
Size: 120 Count (Pack of 1)
I've been using these for years.. They were recommended by my doctor. There's no side effects & they're very good 4-my the relief pain in my joints. The size of the pill is quite large so I recommend that you cut it into if u can't swallow it whole. Dosage is recommended (1) a day
Reviewed in the United States on May 12, 2026 by Mary F

  • OsteoFlex
Size: 120 Count (Pack of 1)
Great price for what you get. Excellent seller and quick delivery.
Reviewed in the United States on June 13, 2026 by ValerieK

  • works fast!
Size: 130 Count (Pack of 1)
helps with my knee pain
Reviewed in the United States on April 28, 2026 by James H. Walton

  • My knee feels so much better
Size: 130 Count (Pack of 1)
Made a huge improvement
Reviewed in the United States on April 15, 2026 by Kaela L.

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