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Nix

Nix Ultra Superlice Treatment, All-in-One Shampoo, 4 Fl Oz & Lice Removal Comb

  • Based on 2,469 reviews
Condition: New
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Availability: In Stock.
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Arrives Monday, Aug 24
Order within 10 hours and 42 minutes
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Size: 1 Count (Pack of 1)


Features

  • Nix Ultra All-in-One Shampoo kills head lice and eggs (nits), including hard-to-kill superlice
  • Nix Ultra Lice Comb assists in removing lice and eggs (nits) from hair after lice treatment
  • Nix Ultra All-in-One Shampoo gently treats and cleanses hair with one-step easy application; no additional shampoo needed
  • Nix Ultra Shampoo is safe for kids and is hypoallergenic, pesticide-free, non-toxic and does not contain parabens, colorants or dyes
  • Nix is the number one pediatrician-recommended lice removal brand* * Based on Pediatrician Survey December 6, 2022

Description

From the number one pediatrician-recommended lice removal brand. Nix Ultra Lice Treatment All-in-One Shampoo is specifically designed to kill superlice. Superlice are the dominant species of head lice and are resistant to traditional pesticide lice treatments. Nix Ultra treatments are pesticide-free and non-toxic. They work by killing lice and superlice through suffocation rather than using harsh chemicals. First, apply Nix Ultra All-in-One Shampoo to hair. Then, remove lice and eggs (nits) from head hair with the Nix Ultra Lice Removal Comb. Nix Ultra All-in-One Shampoo is for use on head hair and safe for use on children 1 year and older. No additional shampoo is needed-, Nix Ultra lice shampoo cleans hair while killing superlice and eggs (nits). Nix lice treatment is trusted by parents and feared by lice. Nix offers a variety of lice combs, shampoos, treatment kits, hair prevention spray and lice spray for furniture and bedding to nix out lice in your home. Based on Pediatrician Survey December 6, 2022.

Product Dimensions ‏ : ‎ 2.4 x 1.93 x 7.08 inches; 5.92 ounces


Item model number ‏ : ‎ ME00115


Date First Available ‏ : ‎ February 1, 2019


Manufacturer ‏ : ‎ Prestige Consumer Healthcare


Best Sellers Rank: #4,196 in Health & Household (See Top 100 in Health & Household) #1 in Lice Treatment Kits


#1 in Lice Treatment Kits:


Customer Reviews: 4.4 4.4 out of 5 stars (2,469)


Item Volume: 4 fluid ounces


Number of Items: 1


Unit Count: 1 Count


Size: 1 Count (Pack of 1)


Brand Name: Nix


Manufacturer: Prestige Consumer Healthcare


UPC: 363736000158


Global Trade Identification Number: 58


Item Weight: 5.92 ounces


Model Number: ME00115


Manufacturer Part Number: ME00115


Item Form: Liquid


Target Species: Humans


Frequently asked questions

If you place your order now, the estimated arrival date for this product is: Monday, Aug 24

Yes, absolutely! You may return this product for a full refund within 30 days of receiving it.

To initiate a return, please visit our Returns Center.

View our full returns policy here.

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Top Amazon Reviews


  • Gets the job done quickly and effectively!
Size: 1 Count (Pack of 1)
Super easy to use, better ingredients and doesn’t smell. I was comfortable applying this and it worked great! Totally worth the money! It goes on more like an oil than a soapy mess, so very convenient and kid friendly.
Reviewed in the United States on July 11, 2026 by Katelynn Cox

  • Works well. Child friendly. Easy to use.
Size: 1 Count (Pack of 1)
Found out my daughter had lice and purchased this immediately. Killed all adult lice on day 1. By around day 4 I saw loose nits far from scalp. After a 2nd treatment for peace of mind and several weeks of fine combing, we are nit free.
Reviewed in the United States on July 13, 2026 by Lizette

  • Nix
Size: 1 Count (Pack of 1)
Great value. Works great.
Reviewed in the United States on July 21, 2026 by Marilyn

  • Works fine. Lice didn't go away completely.
Size: 1 Count (Pack of 1)
Easy to use and safe for kids. Got few lice after the treatment was done. I have to do it again in 9 days.
Reviewed in the United States on April 30, 2026 by Mahmud Reaz

  • Works
Size: 1 Count (Pack of 1)
Here’s what you’re going to do when you have found lice in your kids hair: 1. Anxiety attack because it is one of the grossest things ever and you can’t believe your kid has it 2. Calm down a bit and search the internet for answers and have another anxiety attack as you read horror stories about other parents’ experiences with lice 3. Buy every product you can find that claims it can help with lice Now what should you do? 1. Calm down, it’s ok. Many people have been through this and they succeed. It will take work though, so prepare for it 2. Put Nix shampoo in your child’s hair as directed and watch all the little buggers die (mwahaha) 3. Rinse hair as directed 4. (Optional) have your child use regular shampoo / conditioner after 5. If your child has long hair, brush hair with a regular brush and boil that brush 6. If your child has long hair, get a clip or scrunchee or some kind of hair tie and put most of it up, leaving a lower section out 7. If your child has long hair, put cetaphil lotion on the loose hair to act as a detangler 8. Brush hair with the Terminator lice comb, it’s easiest to brush from the top down with comb over the hair touching the scalp. Brush this small section lots of times until you don’t see any weird little white or brown bits in that section of hair (those are the eggs) 9. Clean the comb with isopropyl alcohol or boiling water. 10. Let down a little more hair, if using a hair tie. Or just move to another section. 11. Repeat combing small sections until you’ve combed all hair. 12. Have child take a shower to clean out the lotion (if using) 12b. Wash everything that touches anyone’s hair in 130 degree F water. You might need to adjust your water heater, there should be a knob on it with different temp settings, so look at the directions on how to set it. And dry everything on high heat for 20+ minutes 13. Check child’s hair every day for more lice. If more lice are found, check Nix directions to see if it’s safe to repeat, but definitely do the combing procedure 14. On the 5th day, repeat combing procedure no matter if lice are found or not 15. On the 9-10th day, repeat Nix treatment and combing procedure. This is a good day to repeat treatment based on the life cycle of lice. Eggs will have hatched, but the new lice will not have laid eggs yet. 16. Keep repeating everything until no lice are found 17. Treat yourself, you deserve it ... show more
Reviewed in the United States on February 2, 2024 by K. Brisbin

  • Effective and Easy-to-Use Lice Solution
Size: 1 Count (Pack of 1)
The lice treatment kit is designed to manage and eliminate lice infestations. However, a notable flaw of the treatment is that it may not kill all lice. Some treatments have been reported to only incapacitate the lice temporarily, rather than killing them outright. This means that while the lice may be rendered inactive or “knocked up” by the treatment, they are not necessarily eradicated, and there could be a risk of the infestation persisting or recurring. It’s important to follow up with combing and possibly a second treatment to ensure all lice and nits are removed ... show more
Reviewed in the United States on June 4, 2024 by Lisandro R.

  • Triumph of branding over efficacy
Size: 1 Count (Pack of 1)
I have no idea why Nix keeps getting recommended as a top lice treatment. We tried the permethrin version (creme rinse) first, and it killed some of the lice but definitely not all of them. The Ultra All-in-One shampoo is just scented mineral oil; you might as well buy a cheap bottle of your local store brand mineral oil because there is no other active ingredient in this product. I'm trying other brands with dimethicone or sodium chloride for our next round. The packaging on all Nix products is misleading and it's wildly overpriced considering how badly it works. ... show more
Reviewed in the United States on August 5, 2024 by Joni

  • Always have a bottle in your cabinet!
Size: 1 Count (Pack of 1)
I wish we never needed this, but it is good to have on hand. We have elementary age kids and when they’ve had lice, this has done the trick.
Reviewed in the United States on May 23, 2026 by Lisa Savalli

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