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Nike

Nike Women's Run Defy Road Running Shoes

  • Based on 1,026 reviews
Condition: New
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$52.97 Why this price?
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Availability: Only 7 left in stock, order soon!
Fulfilled by Amazon
Arrives Thursday, Oct 1
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Size: 7.5


Color: White/Blue Void/Football Grey/Work Blue


Description

Enhanced Traction Increased rubber on the outsole for traction and durability. Cushioned Comfort Foam midsole and flex grooves for a soft, cushioned ride. Flexible Ride Durable and flexible Waffle outsole keeps you on the move. Engineered for Every Mile Show Up Ready Make Every Rep Count Just Do It

Frequently asked questions

If you place your order now, the estimated arrival date for this product is: Thursday, Oct 1

Yes, absolutely! You may return this product for a full refund within 30 days of receiving it.

To initiate a return, please visit our Returns Center.

View our full returns policy here.

  • Klarna Financing
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  • Financing through Google Pay
Leasing options through Acima may also be available during checkout.

Learn more about financing & leasing here.

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Top Amazon Reviews

    • Great running shoes
These Nike shoes are extremely comfortable from the first wear. They feel lightweight but also very supportive, which makes them great for running, walking, and being on your feet all day. The cushioning absorbs impact well and my feet do not feel tired even after long use. They are also very well made and feel strong and durable. I love the design and how good they look with both workout clothes and casual outfits. These are some of the best athletic shoes I have owned and I would definitely buy them again. ... show more
Reviewed in the United States on February 14, 2026 by The Astronomer
    • Super comfy,supportive, and cute! Super comfy,supportive, and cute!
Review Image by Veronica Gotthard
Review Image by Veronica Gotthard
At first sight, these sneakers are even cuter than I expected! Very comfy and lightweight. They are perfect for what I bought them for ( running on treadmill) they have more cushion and support around the ankles making you feel very “locked in” to the shoe. As if the sneaker is gripping your feet which is very comfortable. For the price, this is a GREAT BUY! love this sneaker! ... show more
Reviewed in the United States on June 15, 2026 Reviewed in the United States on June 15, 2026 by Veronica Gotthard
    • Great fit
Look good and very comfortable Highly recommend
Reviewed in the United States on July 2, 2026 by movie mom
    • Great shoes at a great price
Size: 8 Color: Particle Rose/Hydrogen Blue/Sail/Tattoo
My daughter just ran a cross-country ultra-marathon with these and even though they were the wrong footwear for muddy hilly conditions they held up and helped her take 1st place. They were unrecognizable with all of the caked on mud but after cleaning them up well they look as good as new. I highly recommend these shoes! If they can handle the extreme conditions my daughter exposed them to, they can handle anything! ... show more
Reviewed in the United States on May 23, 2026 by SS
    • Comfortable sneakers Comfortable sneakers
Size: 7.5 Color: Black/White/Wolf Grey
Review Image by So-An
Review Image by So-An
These Nike sneakers are very comfortable and great for everyday wear. The cushioning feels good, and they’re lightweight and easy to walk in for long periods. It’s true to size. The top area fits a-little wide so they don’t give that snug, narrow fit I was hoping for. They still feel comfortable overall, a solid and comfortable sneaker for the price! ... show more
Reviewed in the United States on May 19, 2026 Reviewed in the United States on May 19, 2026 by So-An
    • Fashionable
This sneaker is comfortable and stylish. They fit well and easy to walk in. The color is nice and they are durable. My daughter brought these for my Mommy's Day gift.
Reviewed in the United States on May 5, 2026 by Trish Willis
    • Nike
Size: 6.5 Color: White/Black/Smoke Grey
Love these shoes, wear them for work, so comfy and stylish, I get compliments every time I wear them.
Reviewed in the United States on May 17, 2026 by Virginia Schmidt
    • I recommend these shoes! I recommend these shoes!
Review Image by loyd Oklahoma
They are VERY comfortable. They look great, & should last a long time. I'll update if there's any change. Good value for the price. I got them on sale for $50.
Reviewed in the United States on May 16, 2026 Reviewed in the United States on May 16, 2026 by loyd Oklahoma

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