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Desitin

Desitin Maximum Strength Baby Diaper Rash Cream, 40% Zinc Oxide for Treatment, Relief & Prevention, Hypoallergenic, Phthalate- & Paraben-Free Paste, Protects Skin For Up To 12 Hours, 16 oz

  • Based on 46,262 reviews
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Availability: In Stock.
Fulfilled by Amazon
Arrives Thursday, Mar 12
Order within 12 hours and 28 minutes
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Size: 16 Ounce (Pack of 1)


Features

  • 16-ounce jar of Desitin Maximum Strength Diaper Rash Paste with 40% zinc oxide works on contact to treat and help prevent baby diaper rash discomfort
  • Rich, thick diaper rash cream is formulated with 40% maximum-level zinc oxide and is clinically shown to protect baby's delicate skin for up to 12 hours
  • The maximum strength paste provides effective diaper rash relief by immediately forming a protective barrier on baby's skin to seal out wetness and soothe chafed skin
  • The baby diaper rash paste's hypoallergenic formula is paraben-, phthalate-, and dye-free. It is also Dermatologist- and Pediatrician-tested and is gentle enough for daily use
  • Maximum strength diaper rash paste provides 5-in-1 action to treat, heal, protect, soothe & help prevent diaper rash, for healing you can see & relief your baby can feel. Apply paste as often as needed or when exposure to wet diapers may be prolonged

Description

Desitin Maximum Strength Diaper Rash Paste works to effectively treat and help prevent infant diaper rash discomfort. Made with 40% maximum-level zinc oxide, this rich, thick diaper rash cream soothes and relieves baby's skin on contact by sealing out wetness and protecting chafed skin due to diaper rash. Dermatologist- and pediatrician-tested, it is clinically shown to protect baby's delicate skin for up to 12 hours. The hypoallergenic formula of this diaper rash treatment is gentle enough for daily use and is free of parabens, phthalates, and dyes. Desitin Maximum Strength Diaper Rash Paste provides 5-in-1 action to treat, heal, protect, soothe and prevent diaper rash, for healing you can see and relief your baby can feel. Apply diaper rash paste to skin as liberally as often as necessary, with each diaper change, especially at bedtime or any time when exposure to a wet diaper may be prolonged.

Brand: Desitin


Item Form: Cream


Item Weight: 454 Grams


Age Range (Description): Baby, Infant


Active Ingredients: Zinc Oxide


Is Discontinued By Manufacturer ‏ : ‎ No


Product Dimensions ‏ : ‎ 3.2 x 3.5 x 3.2 inches; 1 Pounds


Item model number ‏ : ‎ J&J048975


Department ‏ : ‎ Children


Date First Available ‏ : ‎ September 26, 2008


Manufacturer ‏ : ‎ Kenvue


Best Sellers Rank: #1,121 in Health & Household (See Top 100 in Health & Household) #1 in Diaper Creams #138 in Sales & Deals


#1 in Diaper Creams:


#138 in Sales & Deals:


Frequently asked questions

If you place your order now, the estimated arrival date for this product is: Thursday, Mar 12

Yes, absolutely! You may return this product for a full refund within 30 days of receiving it.

To initiate a return, please visit our Returns Center.

View our full returns policy here.

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Top Amazon Reviews

    • A household essential that heals fast and protects even better
Size: 16 Ounce (Pack of 1)
A household essential that heals fast and protects even better Desitin Maximum Strength Diaper Rash Cream has been around for decades for a reason—it simply works. The 40% zinc oxide formula is thick, soothing, and forms an instant protective barrier that seals out moisture and promotes healing. It’s the go-to for stubborn rashes that other creams can’t touch, often clearing irritation within a day or two. The cream’s texture is dense but spreads evenly, staying in place through multiple diaper changes or overnight use. It’s gentle enough for newborns yet strong enough for adults dealing with chafing or skin irritation from incontinence pads, sweat, or friction. Because it’s hypoallergenic and free of parabens, phthalates, and dyes, it rarely causes irritation even on sensitive skin. The 16-ounce tub is great value—it lasts for months and is far more economical than small tubes. The only minor drawback is that the paste can be hard to remove completely from skin or fabric if overapplied, and it has a mild medicinal scent that not everyone loves. Bottom line: a trusted, dermatologist-tested classic that lives up to its reputation. If you need fast, reliable relief for diaper rash, chafing, or general skin irritation, Desitin Maximum Strength remains the gold standard for both babies and adults alike. ... show more
Reviewed in the United States on October 19, 2025 by Everyday Reviews
    • Always reliable
Size: 16 Ounce (Pack of 1)
This is a staple in our household because it really creates a thick barrier that protects the skin. It works faster than most other brands I’ve tried, and you can usually see an improvement by the next morning. I’m giving it 4 stars because, while the thickness is what makes it effective, it is quite difficult to wash off your hands after applying it. It’s also a bit messy if it gets on clothes, but in terms of healing a stubborn rash, it’s definitely one of the most reliable products out there ... show more
Reviewed in the United States on January 27, 2026 by Mario Enrique Hernández
    • Great time-tested remedy. Cheaper at Walmart.
Size: 4.8 Ounce (Pack of 1)
This is great stuff and often the only thing that works for minor annoying thingies. My dermatologist 's recommendation . However, Walmart has their own brand of 40% zinc oxide (which is what this is) at 1/5th the price. Ah, the price of advertising.
Reviewed in the United States on January 15, 2026 by HHCCAZ
    • Thick
Size: 4.8 Ounce (Pack of 1)
Works exactly how it should. Thick, protective ointment that stops and soothes diaper rash fast. A little goes a long way, doesn’t sting, and stays put through messy changes. Reliable diaper-bag staple every parent should have.
Reviewed in the United States on January 15, 2026 by Shosh
    • Simply excellent
Size: 16 Ounce (Pack of 1)
-Desitin Maximum Strength Paste is a staple for our baby’s sensitive skin. The 40% zinc oxide formula provides an excellent protective barrier that isn’t too thick. In our experience, it makes rashes disappear in 1-2 uses. It is extremely reliable and we don’t leave the house without it. We prefer this concentration to the 13% zinc oxide (blue label). We don’t leave the house without it and the 16oz tub provides excellent value. ... show more
Reviewed in the United States on January 5, 2026 by Seth M.
    • Good quality product
Size: 16 Ounce (Pack of 1)
Excellent, does the job of preventing diaper rashes. We bought it after the diaper rash started and it helped the skin heal
Reviewed in the United States on February 15, 2026 by Amazon Customer
    • good ole diaper cream
Size: 16 Ounce (Pack of 1)
gets the job done, but the cod liver oil smell is so strong
Reviewed in the United States on February 17, 2026 by Stephanie
    • Great Product
Size: 16 Ounce (Pack of 1)
Works great! Way thicker than the normal stuff and last a lot longer. I like having the jar on the changing table. Easier to get when you only have one hand available.
Reviewed in the United States on February 13, 2026 by Amazon Customer

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