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Critical Immune Defense for Dogs & Cats; Supports Normal Cell Growth - Turkey Tail, Reishi, Shiitake and Maitake Mushroom Formula with Patented White Turmeric Root Extract - 30-Day Supply

  • Based on 1,811 reviews
Condition: New
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Non-returnable due to Food safety reasons

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Availability: In Stock.
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Arrives Tuesday, Jul 21
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Size: Pack of 1 - Standard Size - (30-Day Supply)


Features

  • IMPORTANT STATISTIC - According to the American Veterinary Cancer Society, 47% of dogs and 32% of cats over the age of 10 are diagnosed with some form of cancer.
  • POWERFUL IMMUNE SYSTEM SUPPORT FOR DOGS & CATS - Veterinarian-developed formula that strengthens your pets immune system to help maintain health and support defense against common challenges. Ideal for dogs and cats of all breeds and ages, from active puppies and kittens to senior pets.
  • PROMOTES NORMAL CELL GROWTH - Unique blend of four powerful mushrooms, concentrated white turmeric extract, and vitamins to boost Natural Killer (NK) and T-Helper cells; supports your pets long-term health by helping good cells eliminate abnormalities.
  • REDUCES INFLAMMATION & SUPPORTS IMMUNE RESILIENCE - Formulated to promote a healthy inflammatory response and strengthen your pets natural defenses. Supports the bodys protective barrier against everyday environmental stressors that can challenge immune function. Rich in free-radical fighters to support cellular protection, enhance vitality, and promote a longer, healthier life for your pet.
  • VET-FORMULATED, PREMIUM QUALITY MADE IN THE USA Crafted by scientists and veterinarians using natural ingredients free from artificial flavors, colors, or fillers and produced under strict quality standards for results you can trust.

Brand: VetSmart Formulas


Flavor: Hypo-allergenic Chicken Flavor


Item Form: Powder


Item Weight: 6.34 Ounces


Dog Breed Size: Large


Package Dimensions ‏ : ‎ 4.88 x 2.72 x 2.68 inches; 6.34 ounces


Item model number ‏ : ‎ CID


Date First Available ‏ : ‎ November 25, 2019


Manufacturer ‏ : ‎ Pet Wellness Direct


Best Sellers Rank: #3,151 in Pet Supplies (See Top 100 in Pet Supplies) #11 in Dog Herbal Supplements


#11 in Dog Herbal Supplements:


Customer Reviews: 4.3 4.3 out of 5 stars (1,811)


Flavor: Hypo-allergenic Chicken Flavor


Item Form: Powder


Dog Breed Size: Large


Specific Uses For Product: Immune Defense


Item Weight: 6.34 Ounces


Brand Name: VetSmart Formulas


Manufacturer: Pet Wellness Direct


UPC: 691327266288


Model Number: CID


Manufacturer Part Number: CID


Warranty Description: Three Years From Manufacturing Date As Indicated On Each Jar


Unit Count: 6.34 Ounce


Target Species: Cat


Included Components: Critical Immune Defense


Frequently asked questions

If you place your order now, the estimated arrival date for this product is: Tuesday, Jul 21

This item is non-returnable:

Non-returnable due to Food safety reasons

View our full returns policy here.

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Top Amazon Reviews


  • I AM BACK TO BUY MORE!
Size: Pack of 1 - Standard Size - (30-Day Supply)
Update: We have only one bottle of powder left, so I'm reordering. I still have my grand-dog, Gus, on this supplement, and he is still running and chasing the ball during play time. My son is a firm believer in this product, and so am I. I have my younger female dogs on it as well. It is costly, but when I consider eventual vet bills that might be prevented if dogs have this stuff all their lives, I prefer to keep them healthy now so we can avoid some of the absurdly expensive health issues later in life. I can't seem to leave a vet's office without a three-hundred-dollar bill, and that is for basically nothing. Anything serious can be one or two thousand or much higher. It strikes me as being smarter to try to prevent serious issues for as long as we can, and in the meantime, our three dogs are happy, healthy, and enjoying a good playtime with the ball every day. At mealtime, they don't hesitate to eat, and if we didn't get all the powder mixed in well with their food, they lick the bowls clean, getting every last bit of the supplement. After eating, they circle around to see if another dog left any traces of anything in the bowl, and if one misses some of this supplement powder, they lick it up. So it doesn't taste icky to my dogs. I researched the ingredients and am thinking about finding a human version of this stuff. I think the company has done a stellar job of researching what will actually help our dogs--and I know there are human supplements, made of approximately the same stuff, that reviewers rave about. I'm 76, but who knows? If I get the same nutrients, maybe I'll be more energetic as well and help chase that darned ball! First post: I got this, despite the price, just to see. My son has a seven-year-old Aussie who was no longer wanting to chase the ball, who stood back and just didn't seem to care about playing anymore with our two younger dogs. It was so sad to see! He is still so young. I remembered reading about Critical Immune Defense and seeing good reviews. So, despite the cost, I decided to order some. I gave my grand-dog, Gus, his three scoops (he's a larger dog than my girls, so they only get two) on his food per meal for three days. (I did mention to my son that I was doing so. It is his dog, after all.) So we sailed along for three days, and all of a sudden, my grand-dog, Gus, began bursting forward to chase the ball and play. He was like a puppy again, all excited and racing around. It made my heart swell, because I was thinking, "That Stuff is actually Working!" My son said nothing. So, I thought, okay, fine. I can do without spending all that money on snake poison, even though I believed I was seeing a huge change in my grand-dog, Gus. My thought was, "I saw a placebo effect. I convinced myself, so I believed in the hype." My son didn't mention seeing a difference. So, hello, the stuff is expensive. I decided not to buy anymore. I'm not an idiot. So a few days later, my son calls. (We live on the same property, so our dogs all eat together.) "Mom, are you still giving Gus his supplement?" I thought I had messed up, because I wasn't giving him anything. I was, like, WHAT supplement? My son was, like, that stuff that started making him play like a puppy again! He was very upset that I had stopped giving his dog the CID. He would have been eagerly willing to continue the supplement at his own cost and trouble! The difference in the dog was huge. I popped back, saying that he'd never said a word about how it changed Gus. Why would I continue giving it to him? The stuff is costly! (I hope the company can shave away at their overhead to reduce the cost of product. ) Bottom line, this stuff DOES work! It isn't about buying it and only thinking it works. It truly does, and our Gus is suddenly running and playing like a much younger dog. It has given him a new lease on life. I have decided to also give it to my two younger dogs, hopefully as a preventative supplement. And, hello, I'm researching to find a human-grade supplement with mostly the same ingredients. I could stand a boost energy to make me feel better, too! ... show more
Reviewed in the United States on August 9, 2024 by Catherine Anderson Author

  • Great product
Size: Pack of 1 - Standard Size - (30-Day Supply)
This is a fantastic product. My 13 yr old Australian shepherd started getting bumps, like little tumors. This product helps keep them at bay and actually shrinks them. I highly recommend.
Reviewed in the United States on June 5, 2026 by Chris

  • Helped shrink mass on lymph nodes Helped shrink mass on lymph nodes
Size: Pack of 1 - Standard Size - (30-Day Supply)
I’m actually in shock that this combined with turmeric and antibiotics that weren’t working, has worked! My Labrador developed a squishy mass in neck (lymph nodes) after 24 hrs it’s started leaking and shrinking. My vet said not to use anything else except for antibiotics but I didn’t listen because natural stuff works! ... show more
Reviewed in the United States on May 21, 2026 Reviewed in the United States on May 21, 2026 by Jonelle

  • Good but Pricey
Size: Pack of 1 - Standard Size - (30-Day Supply)
This product works well for my lab, but it’s pricey for the amount you receive.
Reviewed in the United States on April 19, 2026 by Suzanne

  • Animal health
Size: Pack of 1 - Standard Size - (30-Day Supply)
I like what it does for my feral cats..keeping them healthier without colds and eye discharges...Ive noticed good change in them since Ive started using CID
Reviewed in the United States on May 30, 2026 by Amazon Customer

  • IF YOU VALUE YOUR DOGS LIFE…DO NOT BUY!!
Size: Pack of 1 - Standard Size - (30-Day Supply)
I never write reviews but Milky my Bichon Poodle almost died. After I sprinkled this product on his food, he refused to eat it. I coaxed him into eating, not realizing the danger. The next morning, he usually jumps down from my bed, but this time he was whining and needed help. When I placed him on the floor, he couldn’t walk—he couldn’t even stand on his own. I lifted him up, and he began limping across the floor. From what I could tell, only one leg was really working. Panicked, I began to pray over him olive oil mix with 2 drops of oil of oregano with black seed and gave him plenty of water to flush the product out of his system. I’m currently unemployed and was praying we wouldn’t have to go to the vet. The whole reason I bought this product was to avoid a vet visit as a preventative measure. He’s 15 yrs, but other than some possible dental issues, he’s generally fine. That entire day, he struggled to walk, limping and needing help up and down the stairs. It was a mess. I even called my pastor, who prayed for him over the phone. Then, late in the night, I heard him jump off the bed. Thank God! The next day, he was doing much better and could walk again—still a little unsteady, but by the evening, it was like nothing had happened. He was back to running around as usual. Stay clear of this stuff! I went back and read the one-star reviews, and I saw that two dogs had died after using this product. If I had seen those reviews earlier, I never would have bought it. Of course there’s no refund. If your dog refuses to eat something, trust them. Do not push it. I’m so blessed he made it through. ... show more
Reviewed in the United States on February 23, 2025 by Hollywood1021

  • My dog seemed not to mind the taste/smell My dog seemed not to mind the taste/smell
Size: Pack of 1 - Standard Size - (30-Day Supply)
I started using this product after my dog was diagnosed with lymphoma...unfortunately, after two and a half months the cancer had spread throughout her body...I'm not sure if I believe the testimonials with people saying it helped their pet fight cancer, allowing them to live for many years....I'll give 3 stars for the fact seem didn't seemed to mind the taste/smell when mixed with her food.....R.I.P. Cynder 🙏🏼💔 ... show more
Reviewed in the United States on March 25, 2026 Reviewed in the United States on March 25, 2026 by Geraldo H.

  • Keep your pet healthy..
Size: Pack of 1 - Standard Size - (30-Day Supply)
Mushrooms are a popular natural supplement... But tends to be on the expensive side, from natural stores.... I started giving my rescue dog this immediately. Even though she was only five..... All I know.Is she's a happy girl right now?And i'm hoping to keep her that way!!!
Reviewed in the United States on April 27, 2026 by roseanna

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