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Nike

Nike Men's Run Defy Road Running Shoes

  • Based on 2,299 reviews
Condition: New
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$48.75 Why this price?
Save $16.25 was $65.00

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As low as $8.13 / mo
  • – 6-month term
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Availability: In Stock.
Fulfilled by Amazon
Arrives Wednesday, Aug 26
Order within 6 hours and 9 minutes
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Size: 10


Color: Black/Cool Grey/University Red/White


Description

Cushioned Comfort Foam midsole and flex grooves provide a cushioned and soft ride. Flexible Ride Durable and flexible Waffle outsole helps keep you on the move. Enhanced Traction Increased rubber on the outsole for traction and durability. Engineered for Every Mile Show Up Ready Make Every Rep Count Just Do It

Frequently asked questions

If you place your order now, the estimated arrival date for this product is: Wednesday, Aug 26

Yes, absolutely! You may return this product for a full refund within 30 days of receiving it.

To initiate a return, please visit our Returns Center.

View our full returns policy here.

  • Klarna Financing
  • Affirm Pay in 4
  • Affirm Financing
  • Afterpay Financing
  • Zip Pay in 4
  • Financing through Apple Pay
  • Financing through Google Pay
Leasing options through Acima may also be available during checkout.

Learn more about financing & leasing here.

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Top Amazon Reviews

    • They look insane!
Size: 11.5 Color: Black/White
Review Image by Yohan
Review Image by Yohan
These sneakers are super comfy. Nike never lets me down. I think they’re a great deal and honestly, they look insane! They feel very light, but at the same time very high quality and durable.
Reviewed in the United States on July 18, 2026 by Yohan
    • VERY HAPPY WITH THESE SHOES!
Great price and super comfortable. Size was a little off so I used a stretcher and placed the shoes in the sun and it worked perfect! Best fit ever!!! Very happy! It is like wearing air for shoes!!!!
Reviewed in the United States on June 26, 2026 by Phil Bonafede
    • Worked well despite not being 2E shoe
Size: 11.5 Color: White/Pure Platinum/Black
Was having size issues and foot pain from other shoes and ordered these, I normally wear a 2E in my running shoes and these as a regular D still have a good width in the toe box area. I wore them to Germany we were did a lot of walking and sight seeing and the padding is comfy and the size was very accommodating ... show more
Reviewed in the United States on July 29, 2026 by Malcolm A Taylor
    • Very Comfortable
Size: 10.5 Color: White/Pure Platinum/Black
I like these sneakers because I needed white sneakers for summer fashions. They are made by Nike so I know they are well made. I get compliments and my summer fashion looks and the sneakers work well and go with just about everything
Reviewed in the United States on August 12, 2026 by Charlz Papovitch
    • Great shoes!
Size: 6 Color: Black/Cool Grey/University Red/White
Love these shoes They look great, and are very comfortable. So far I've worn them to work where I'm on my feet most of the day and some light walking 1-3mi without pain after afterwards, which is great for a new shoe. They do fit a little narrow but otherwise true to size.
Reviewed in the United States on April 17, 2026 by Sarah Irie
    • Very happy with this purchase.
My son absolutely loves these shoes! They offer fantastic comfort right out of the box with zero break-in time needed. Lightweight, supportive, and stylish enough for everyday wear or hitting the road.
Reviewed in the United States on July 26, 2026 by SP
    • Great shoes.
Size: 13 Color: Black/Cool Grey/University Red/White
These shoes are really comfortable and fit nicely.
Reviewed in the United States on August 3, 2026 by Nathanael Makool
    • Good shoes for the price
Ordered these for my husband and they fit good and he says they are comfy. They look great on him!
Reviewed in the United States on June 29, 2026 by Briana Escobedo

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