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Nike

Nike Women's Run Defy Road Running Shoes

  • Based on 1,390 reviews
Condition: New
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$65.00 Why this price?
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Availability: In Stock.
Fulfilled by Amazon
Arrives Sep 25 – Sep 26
Order within 15 hours and 29 minutes
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Size: 6.5


Color: Black/White/Wolf Grey


Description

Cushioned Comfort Foam midsole and flex grooves provide a cushioned and soft ride. Flexible Ride Durable and flexible Waffle outsole helps keep you on the move. Enhanced Traction Increased rubber on the outsole for traction and durability. Engineered for Every Mile Show Up Ready Make Every Rep Count Just Do It

Frequently asked questions

If you place your order now, the estimated arrival date for this product is: Sep 25 – Sep 26

Yes, absolutely! You may return this product for a full refund within 30 days of receiving it.

To initiate a return, please visit our Returns Center.

View our full returns policy here.

  • Klarna Financing
  • Affirm Pay in 4
  • Affirm Financing
  • Afterpay Financing
  • Zip Pay in 4
  • Financing through Apple Pay
  • Financing through Google Pay
Leasing options through Acima may also be available during checkout.

Learn more about financing & leasing here.

Similar Products

Top Amazon Reviews

    • The Perfect Shoes for Long Standing!
Size: 6 Color: Black/Anthracite
Excellent fit! Arch support! Small and narrow feet friendly! Lightweight and super comfy! My sister stands all day for work and I got her these and she’s in love with them! She says they are amazing and soft. Easy to put on and take off. Worth every penny! Don’t hesitate, buy them! For reference, my sister wears size 6 and size 6 fits her perfectly with enough wiggle room. So they are indeed true to size! ... show more
Reviewed in the United States on August 10, 2026 by Mizz Johnson
    • Super comfy,supportive, and cute!
Size: 6.5 Color: White/Pure Platinum/Black
Review Image by Veronica Gotthard
Review Image by Veronica Gotthard
At first sight, these sneakers are even cuter than I expected! Very comfy and lightweight. They are perfect for what I bought them for ( running on treadmill) they have more cushion and support around the ankles making you feel very “locked in” to the shoe. As if the sneaker is gripping your feet which is very comfortable. For the price, this is a GREAT BUY! love this sneaker! ... show more
Reviewed in the United States on June 15, 2026 by Veronica Gotthard
    • Comfortable
Size: 10.5 Color: Sail/Pink Smoke-white-pink Rise
I’m not a runner, but need some good study and comfortable all day shoes. These are just right. I usually wear size 10, but because of my prior experiences buying Nike shoes, I ordered 1/2 size bigger. They fit perfectly. If you are looking for a less bulky cushioned pair of tennis shoes, I recommend it! The color is nice! ... show more
Reviewed in the United States on August 23, 2026 by GO
    • Size up a half size- seriously!
Size: 8 Color: White/Pure Platinum/Black
These shoes are wonderful and also way small! I have been wearing them in pain for months, but I just decided that I will buy a new pair a half size up and give the others away. They look great, are light weight and very supportive. I should have returned them when I still could but somehow I though they would stretch. I love the bright white and they wash up beautifully. ... show more
Reviewed in the United States on August 2, 2026 by Bejaune
    • Worth the purchase
Size: 7 Color: Black/Anthracite
Very comfortable. I stand for 12 hrs in a warehouse and these were still holding up after I got home. They have a good amount of cushion.They are great for walking all day. The toe box is slightly narrow. These are a great value for the price.
Reviewed in the United States on August 9, 2026 by nicole tom
    • Three weeks to receive a pair of shoes
Size: 9 Color: Black/Elemental Pink/Hyper Pink
Comfortable shoe. It took 3 weeks to receive my item. Delivery was delayed twice. Finally received them today. The box was all smashed up and broken.
Reviewed in the United States on August 23, 2026 by Leticia
    • True to size
Size: 8 Color: White/Pure Platinum/Black
True to size. Nicely made. Perfect for sports activities such as cheer or dance. Will be purchasing again.
Reviewed in the United States on August 19, 2026 by Laura Aranda
    • Favorite new shoes
Love these shows very comfortable and look nice. True to size light weight lots of cushion and price was great. I typically wear a 10 and that’s what I ordered and fit perfectly.
Reviewed in the United States on July 9, 2026 by Sara Niesen

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