Search  for anything...

Nike Women's Run Defy Road Running Shoes

  • Based on 0 reviews
Condition: New
Checking for the best price...
$65.00 Why this price?
Save $7.98 was $72.98

Buy Now, Pay Later


As low as $10.83 / mo
  • – 6-month term
  • – No impact on credit
  • – Instant approval decision
  • – Secure and straightforward checkout

Ready to go? Add this product to your cart and select a plan during checkout.

Payment plans are offered through our trusted finance partners Klarna, Affirm, Afterpay, Apple Pay, and PayTomorrow. No-credit-needed leasing options through Acima may also be available at checkout.

Learn more about financing & leasing here.

Selected Option

Free shipping on this product

FREE 30-day refund/replacement

To qualify for a full refund, items must be returned in their original, unused condition. If an item is returned in a used, damaged, or materially different state, you may be granted a partial refund.

To initiate a return, please visit our Returns Center.

View our full returns policy here.


Availability: In Stock.
Fulfilled by Amazon

Arrives Sunday, Mar 22
Order within 21 minutes
Available payment plans shown during checkout

Protection Plan Protect Your Purchase
Checking for protection plans...

Size: 8


Color: White/Black/Smoke Grey


This product has no description

Frequently asked questions

If you place your order now, the estimated arrival date for this product is: Sunday, Mar 22

Yes, absolutely! You may return this product for a full refund within 30 days of receiving it.

To initiate a return, please visit our Returns Center.

View our full returns policy here.

  • Klarna Financing
  • Affirm Pay in 4
  • Affirm Financing
  • Afterpay Financing
  • PayTomorrow Financing
  • Financing through Apple Pay
Leasing options through Acima may also be available during checkout.

Learn more about financing & leasing here.

Top Amazon Reviews


  • Great running shoes
These Nike shoes are extremely comfortable from the first wear. They feel lightweight but also very supportive, which makes them great for running, walking, and being on your feet all day. The cushioning absorbs impact well and my feet do not feel tired even after long use. They are also very well made and feel strong and durable. I love the design and how good they look with both workout clothes and casual outfits. These are some of the best athletic shoes I have owned and I would definitely buy them again. ... show more
Reviewed in the United States on February 14, 2026 by The Astronomer

  • Great buy!
I really like it, its light, confortable, true to size, good support and breathable! And more pretty than the picture!
Reviewed in the United States on January 22, 2026 by Chayil

  • Comfortable
Size: 8.5 Color: Ghost/Midnight Navy/Summit White
These are so comfortable and lightweight. I have fat feet and they were perfect. I normally wear a 7.5 in other shoes and I have bought Nikes before based on that which were too small to the point it would bruise my toenail. I got these in 8.5 and they were a perfect fit! So size up from your regular shoe size in other brands. No blisters after the first wear, laces stayed tied, and my feet weren’t exhausted after all day wear. I haven’t ran in them because let’s be honest- I don’t run, but for gym stuff and walking- they were perfect. The color is cute as well just as pictured. ... show more
Reviewed in the United States on December 13, 2025 by Jakki Jakki

  • Great Work Shoe
Great shoe definitely worth the money, fit true to size and comfortable for long standing
Reviewed in the United States on February 4, 2026 by elma washington

  • Lightweight but narrow
Wanted to love, lightweight and comfortable. Just too narrow, even a half size up.
Reviewed in the United States on January 14, 2026 by Dakota Olberding

  • Super comfortable and stylish
Size: 8.5 Color: Black/White/Wolf Grey
These are very lightweight and comfortable. I got the black ones and they look great! I bought a size 8.5 because I typically have to size up with Nike. I wear a size 8 in other brands. So for me, personally, these are not true to size and you should consider sizing up at least a half size.
Reviewed in the United States on January 18, 2026 by Elle

  • Comfortable and supportive!
Size: 11 Color: White/Pure Platinum/Black
Very comfortable and supportive. Great if you walk a lot!
Reviewed in the United States on January 29, 2026 by Rachel Roschen

  • Weakness of right side shoe
The left shoe is great, as good as all my Nike shoes have ever been. I felt something snap in the sole of the right shoe and since then, while walking, I feel an uncomfortable indentation under the center part of my foot.
Reviewed in the United States on January 3, 2026 by Gwenn Holler

Can't find a product?

Find it on Amazon first, then paste the link below.
Checking for best price...