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Nike Men's Run Defy Road Running Shoes

  • Based on 85 reviews
Condition: New
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Availability: Only 6 left in stock, order soon!
Fulfilled by Amazon

Arrives Jun 13 – Jun 15
Order within 18 hours and 10 minutes
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Size: 12


Color: White/Black


This product has no description

Frequently asked questions

If you place your order now, the estimated arrival date for this product is: Jun 13 – Jun 15

Yes, absolutely! You may return this product for a full refund within 30 days of receiving it.

To initiate a return, please visit our Returns Center.

View our full returns policy here.

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Leasing options through Acima may also be available during checkout.

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Top Amazon Reviews


  • Great, comfortable, nice looking sneaker.
Size: 9.5 Color: Black/White
Attractive, comfortable sneaker. Can stand all day in comfort. The black with white styling is a sharp look. Price is what is comparable to other sneakers. These are high quality, no issues with materials. Ease of cleaning. Haven’t had them long enough to deal with this issue. Did waterproof for easy cleaning. Don’t expect waterproof results due to being a mesh style. Size is true. ... show more
Reviewed in the United States on May 11, 2026 by doc

  • Great look and feel
Good looking and feel shoe. Runs a little small in size. Great and comfortable shoes for running, cross fit or walking.
Reviewed in the United States on April 7, 2026 by Puntadevista

  • Fantastic sneakers
Very comfortable and stylish, exactly what I wanted and a great value for the price!
Reviewed in the United States on April 26, 2026 by timmayyyyy

  • Nike Shoes
Size: 8.5 Color: White/Black
I really liked these Nike running shoes. They are comfortable, lightweight, and perfect for daily runs. The design looks great, and they provide very good support while running.
Reviewed in the United States on May 19, 2026 by Kattyta Jimenez

  • Great shoes!
Size: 6 Color: Black/Cool Grey/University Red/White
Love these shoes They look great, and are very comfortable. So far I've worn them to work where I'm on my feet most of the day and some light walking 1-3mi without pain after afterwards, which is great for a new shoe. They do fit a little narrow but otherwise true to size.
Reviewed in the United States on April 17, 2026 by Sarah Irie

  • Nike Run Defy Shoes....... Nike Run Defy Shoes.......
Size: 12 Color: Black/Black/Dark Hazel/Light Khaki
I purchased these Nike Men's Run Defy Road Running Shoes for my husband’s birthday. The mesh on the upper adds breathability, keeping his feet cooler during activity. The foam mid-sole provides a soft, comfortable ride, and the flex grooves create a cushioned effect while running. For reference, his normal size is 11.5, however I ordered a size 12 which made the fit roomy and perfect. He really likes the shoes and mentioned that they feel both breathable and comfortable. The waffle outer sole is made of durable, flexible material that supports movement, and the added rubber on the sole provides traction and longevity. They feel great on his feet and have made his runs and daily walks much more comfortable. My husband is meticulous about keeping his shoes clean. He utilizes a toothbrush along with Dawn Extra-Strength Foaming Power-Wash dish liquid to maintain/clean them. ... show more
Reviewed in the United States on April 5, 2026 Reviewed in the United States on April 5, 2026 by Trué

  • Nike, Nike, Nike
Size: 10 Color: Black/Cool Grey/University Red/White
I love Nike's. I love these shoes. They look good, fit good, and feel good. Price is great as well.
Reviewed in the United States on May 4, 2026 by david

  • Perfect!!!
Size: 7.5 Color: White/Pure Platinum/Black
Love them! So soft and cushiony. If you’re looking for something that makes you feel good while working out…these are it!! Seems to be very durable. Not slip-ons. You have to tie that laces, but I don’t mind. So glad that I sized a half size up, otherwise would have been too small. I could have sized up a whole size and they still wouldn’t be too big. Walking is like a dream. Material is excellent and not cheap feeling or looking like the stuff they’re using to make shoes now. They look very stylish on my feet. They don’t look long like fish heads and the bottom heal doesn’t sit up like an orthopedic shoe. Should have gotten these a long time ago! ... show more
Reviewed in the United States on May 14, 2026 by Carllotta

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